Affinity Data by PubMed id=10354408

PubMed code 10354408

Found 58 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077548 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50072215 (1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...) Show SMILES CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1 \|c:4\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50072233 (1-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...) Show SMILES C(Oc1nsnc1C12CN3CC1C2C3)C#Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50003359 (5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...) Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1 \|t:13\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro Muscarinic acetylcholine receptor M2 binding was evaluated in rat brain membranes by using [3H]- Oxo-M				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077557 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Fc1ccc(cc1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077559 (1-{4-[3-(3-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1cccc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077547 (1-{4-[3-(3-Fluoro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Fc1cccc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077558 (1-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,2,5]thiadia...) Show SMILES C(Sc1nsnc1C12CN3CC1C2C3)C#Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077554 (1-{4-[3-(3,5-Difluoro-phenyl)-prop-2-ynylsulfanyl]...) Show SMILES Fc1cc(F)cc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077550 (1-{4-[3-(3,5-Difluoro-phenyl)-prop-2-ynyloxy]-[1,2...) Show SMILES Fc1cc(F)cc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro Muscarinic acetylcholine receptor M2 binding was evaluated in rat brain membranes by using [3H]- Oxo-M				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077551 (1-{4-[3-(3-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Clc1cccc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077562 (1-{4-[3-(3-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Clc1cccc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077549 (1-{4-[3-(4-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Clc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077556 (1-{4-[3-(3-Chloro-5-fluoro-phenyl)-prop-2-ynyloxy]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077552 (1-{4-[3-(3-Chloro-5-fluoro-phenyl)-prop-2-ynylsulf...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50065223 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...) Show SMILES COc1cccc(c1)C#CCO\N=C1/CN2CCC1C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro Muscarinic acetylcholine receptor M2 binding was evaluated in rat brain membranes by using [3H]- Oxo-M				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077561 (1-{4-[3-(4-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Clc1ccc(cc1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077553 (1-{4-[3-(3,5-Dichloro-phenyl)-prop-2-ynylsulfanyl]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	788	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077555 (3-[3-(3,5-Dichloro-phenyl)-prop-2-ynyloxy]-4-tricy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077558 (1-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,2,5]thiadia...) Show SMILES C(Sc1nsnc1C12CN3CC1C2C3)C#Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	853	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077554 (1-{4-[3-(3,5-Difluoro-phenyl)-prop-2-ynylsulfanyl]...) Show SMILES Fc1cc(F)cc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077559 (1-{4-[3-(3-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1cccc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	683	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50003359 (5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...) Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1 \|t:13\| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	135	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077562 (1-{4-[3-(3-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Clc1cccc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	673	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50072233 (1-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...) Show SMILES C(Oc1nsnc1C12CN3CC1C2C3)C#Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	779	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at Muscarinic acetylcholine receptor M2 by inhibiting forskolin induced c-AMP formation in CHO-M2 cells				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077556 (1-{4-[3-(3-Chloro-5-fluoro-phenyl)-prop-2-ynyloxy]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077552 (1-{4-[3-(3-Chloro-5-fluoro-phenyl)-prop-2-ynylsulf...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077551 (1-{4-[3-(3-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Clc1cccc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077553 (1-{4-[3-(3,5-Dichloro-phenyl)-prop-2-ynylsulfanyl]...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077559 (1-{4-[3-(3-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1cccc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its ability to stimulate phosphoinositol (PI) hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acety...				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077561 (1-{4-[3-(4-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Clc1ccc(cc1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077550 (1-{4-[3-(3,5-Difluoro-phenyl)-prop-2-ynyloxy]-[1,2...) Show SMILES Fc1cc(F)cc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50072215 (1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...) Show SMILES CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1 \|c:4\| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	111	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077556 (1-{4-[3-(3-Chloro-5-fluoro-phenyl)-prop-2-ynyloxy]...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077561 (1-{4-[3-(4-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Clc1ccc(cc1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077562 (1-{4-[3-(3-Chloro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Clc1cccc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077550 (1-{4-[3-(3,5-Difluoro-phenyl)-prop-2-ynyloxy]-[1,2...) Show SMILES Fc1cc(F)cc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077557 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Fc1ccc(cc1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077552 (1-{4-[3-(3-Chloro-5-fluoro-phenyl)-prop-2-ynylsulf...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	763	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077558 (1-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,2,5]thiadia...) Show SMILES C(Sc1nsnc1C12CN3CC1C2C3)C#Cc1ccccc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50003359 (5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...) Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1 \|t:13\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency towards Muscarinic acetylcholine receptor M2 by inhibiting forskolin induced c-AMP formation in CHO-M2 cells				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077554 (1-{4-[3-(3,5-Difluoro-phenyl)-prop-2-ynylsulfanyl]...) Show SMILES Fc1cc(F)cc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency towards Muscarinic acetylcholine receptor M2 by inhibiting forskolin induced c-AMP formation in CHO-M2 cells				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077551 (1-{4-[3-(3-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Clc1cccc(c1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50065223 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...) Show SMILES COc1cccc(c1)C#CCO\N=C1/CN2CCC1C2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.67E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency towards Muscarinic acetylcholine receptor M2 by inhibiting forskolin induced c-AMP formation in CHO-M2 cells				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077553 (1-{4-[3-(3,5-Dichloro-phenyl)-prop-2-ynylsulfanyl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	528	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077548 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	791	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077547 (1-{4-[3-(3-Fluoro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Fc1cccc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50072233 (1-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...) Show SMILES C(Oc1nsnc1C12CN3CC1C2C3)C#Cc1ccccc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077555 (3-[3-(3,5-Dichloro-phenyl)-prop-2-ynyloxy]-4-tricy...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50072215 (1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...) Show SMILES CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1 \|c:4\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	241	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077557 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Fc1ccc(cc1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077549 (1-{4-[3-(4-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Clc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50077548 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50065223 (1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-p...) Show SMILES COc1cccc(c1)C#CCO\N=C1/CN2CCC1C2 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.12E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of phosphoinositol hydrolysis in the mouse fibroblast cell line A9L-M1 expressing Muscarinic acetylcholine receptor M1.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077547 (1-{4-[3-(3-Fluoro-phenyl)-prop-2-ynylsulfanyl]-[1,...) Show SMILES Fc1cccc(c1)C#CCSc1nsnc1C12CN3CC1C2C3 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	904	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%