new BindingDB logo
myBDB logout

PubMed code 18077160

Compile data set for download or QSAR
Found 126 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372295
PNG
(CHEMBL429914)
Show SMILES C[C@@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.390n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372292
PNG
(CHEMBL441903)
Show SMILES C[C@@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372290
PNG
(CHEMBL269951)
Show SMILES C[C@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372322
PNG
(CHEMBL271898)
Show SMILES COc1ccc(CCN2CCC[C@H]2C)cc1
Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372294
PNG
(CHEMBL402187)
Show SMILES C[C@@H]1CCCN1CCc1nc(oc1C)-c1ccccc1
Show InChI InChI=1S/C17H22N2O/c1-13-7-6-11-19(13)12-10-16-14(2)20-17(18-16)15-8-4-3-5-9-15/h3-5,8-9,13H,6-7,10-12H2,1-2H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372295
PNG
(CHEMBL429914)
Show SMILES C[C@@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372291
PNG
(CHEMBL271661)
Show SMILES C(Cc1ccc(OCc2ccccc2)cc1)N1CCCC1
Show InChI InChI=1S/C19H23NO/c1-2-6-18(7-3-1)16-21-19-10-8-17(9-11-19)12-15-20-13-4-5-14-20/h1-3,6-11H,4-5,12-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372304
PNG
(CHEMBL257915)
Show SMILES C[C@@H]1CCCN1CCc1cccc(C)c1
Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372303
PNG
(CHEMBL403052)
Show SMILES C[C@@H]1CCCN1CCc1ccc(C)cc1
Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372290
PNG
(CHEMBL269951)
Show SMILES C[C@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372335
PNG
(CHEMBL402872)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)N(C)C
Show InChI InChI=1S/C15H24N2/c1-13-5-4-11-17(13)12-10-14-6-8-15(9-7-14)16(2)3/h6-9,13H,4-5,10-12H2,1-3H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372292
PNG
(CHEMBL441903)
Show SMILES C[C@@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.10n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372323
PNG
(CHEMBL404532)
Show SMILES COc1ccc(CCN2CCC[C@@H]2C)cc1
Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
8.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372305
PNG
(CHEMBL272141)
Show SMILES C[C@H]1CCCN1CCc1c(C)cc(C)cc1C
Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
10n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372329
PNG
(CHEMBL270630)
Show SMILES C[C@@H]1CCCN1CCc1c(C)cc(C)cc1C
Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
11n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372322
PNG
(CHEMBL271898)
Show SMILES COc1ccc(CCN2CCC[C@H]2C)cc1
Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
12n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372296
PNG
(CHEMBL402377)
Show SMILES C[C@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
14n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372318
PNG
(CHEMBL402220)
Show SMILES COc1ccc2[nH]c(CCN3CCC[C@H]3C)cc2c1
Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
15n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372324
PNG
(CHEMBL439429)
Show SMILES COc1cccc(CCN2CCC[C@H]2C)c1
Show InChI InChI=1S/C14H21NO/c1-12-5-4-9-15(12)10-8-13-6-3-7-14(11-13)16-2/h3,6-7,11-12H,4-5,8-10H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
16n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372339
PNG
(CHEMBL255141)
Show SMILES C[C@@H]1CCCN1CCc1ccns1
Show InChI InChI=1S/C10H16N2S/c1-9-3-2-7-12(9)8-5-10-4-6-11-13-10/h4,6,9H,2-3,5,7-8H2,1H3/t9-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
17n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372321
PNG
(CHEMBL272988)
Show SMILES C[C@H]1CCCN1CCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C15H20N2/c1-12-5-4-9-17(12)10-8-14-11-13-6-2-3-7-15(13)16-14/h2-3,6-7,11-12,16H,4-5,8-10H2,1H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
18n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372334
PNG
(CHEMBL257235)
Show SMILES C[C@H]1CCCN1CCc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C13H18N2O2/c1-11-3-2-9-14(11)10-8-12-4-6-13(7-5-12)15(16)17/h4-7,11H,2-3,8-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372331
PNG
(CHEMBL404834)
Show SMILES C[C@@H]1CCCN1CCc1ccccc1O
Show InChI InChI=1S/C13H19NO/c1-11-5-4-9-14(11)10-8-12-6-2-3-7-13(12)15/h2-3,6-7,11,15H,4-5,8-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
21n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372317
PNG
(CHEMBL271237)
Show SMILES Cc1oc(nc1CCN1CCCC1)-c1ccccc1
Show InChI InChI=1S/C16H20N2O/c1-13-15(9-12-18-10-5-6-11-18)17-16(19-13)14-7-3-2-4-8-14/h2-4,7-8H,5-6,9-12H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
26n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372313
PNG
(CHEMBL257911)
Show SMILES C[C@H]1CCCN1CCc1ccc(C)cc1
Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
27n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372298
PNG
(CHEMBL402415)
Show SMILES C[C@H]1CCCN1CCc1nc(oc1C)-c1ccccc1
Show InChI InChI=1S/C17H22N2O/c1-13-7-6-11-19(13)12-10-16-14(2)20-17(18-16)15-8-4-3-5-9-15/h3-5,8-9,13H,6-7,10-12H2,1-2H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
28n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372304
PNG
(CHEMBL257915)
Show SMILES C[C@@H]1CCCN1CCc1cccc(C)c1
Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372293
PNG
(CHEMBL270410)
Show SMILES C(Cc1ccc2ccccc2c1)N1CCCC1
Show InChI InChI=1S/C16H19N/c1-2-6-16-13-14(7-8-15(16)5-1)9-12-17-10-3-4-11-17/h1-2,5-8,13H,3-4,9-12H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372327
PNG
(CHEMBL404912)
Show SMILES COc1ccccc1CCN1CCC[C@@H]1C
Show InChI InChI=1S/C14H21NO/c1-12-6-5-10-15(12)11-9-13-7-3-4-8-14(13)16-2/h3-4,7-8,12H,5-6,9-11H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
31n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372315
PNG
(CHEMBL257914)
Show SMILES C[C@H]1CCCN1CCc1cccc(C)c1
Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
32n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372340
PNG
(CHEMBL406698)
Show SMILES C[C@H]1CCCN1CCc1ccns1
Show InChI InChI=1S/C10H16N2S/c1-9-3-2-7-12(9)8-5-10-4-6-11-13-10/h4,6,9H,2-3,5,7-8H2,1H3/t9-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
33n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372337
PNG
(CHEMBL402873)
Show SMILES C[C@@H]1CCCN1CCc1cccs1
Show InChI InChI=1S/C11H17NS/c1-10-4-2-7-12(10)8-6-11-5-3-9-13-11/h3,5,9-10H,2,4,6-8H2,1H3/t10-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
34n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372310
PNG
(CHEMBL408259)
Show SMILES CCc1ccc(CCN2CCC[C@H]2C)nc1
Show InChI InChI=1S/C14H22N2/c1-3-13-6-7-14(15-11-13)8-10-16-9-4-5-12(16)2/h6-7,11-12H,3-5,8-10H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
34n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372302
PNG
(CHEMBL404375)
Show SMILES COc1ccccc1CCN1CCC[C@H]1C
Show InChI InChI=1S/C14H21NO/c1-12-6-5-10-15(12)11-9-13-7-3-4-8-14(13)16-2/h3-4,7-8,12H,5-6,9-11H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
35n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372329
PNG
(CHEMBL270630)
Show SMILES C[C@@H]1CCCN1CCc1c(C)cc(C)cc1C
Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
35n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372303
PNG
(CHEMBL403052)
Show SMILES C[C@@H]1CCCN1CCc1ccc(C)cc1
Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
37n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372291
PNG
(CHEMBL271661)
Show SMILES C(Cc1ccc(OCc2ccccc2)cc1)N1CCCC1
Show InChI InChI=1S/C19H23NO/c1-2-6-18(7-3-1)16-21-19-10-8-17(9-11-19)12-15-20-13-4-5-14-20/h1-3,6-11H,4-5,12-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372318
PNG
(CHEMBL402220)
Show SMILES COc1ccc2[nH]c(CCN3CCC[C@H]3C)cc2c1
Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
41n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372301
PNG
(CHEMBL272307)
Show SMILES COc1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C13H19NO/c1-15-13-6-4-12(5-7-13)8-11-14-9-2-3-10-14/h4-7H,2-3,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
41n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372336
PNG
(CHEMBL271489)
Show SMILES C[C@H]1CCCN1CCc1ccc(cc1)N(C)C
Show InChI InChI=1S/C15H24N2/c1-13-5-4-11-17(13)12-10-14-6-8-15(9-7-14)16(2)3/h6-9,13H,4-5,10-12H2,1-3H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
43n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372335
PNG
(CHEMBL402872)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)N(C)C
Show InChI InChI=1S/C15H24N2/c1-13-5-4-11-17(13)12-10-14-6-8-15(9-7-14)16(2)3/h6-9,13H,4-5,10-12H2,1-3H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
43n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372294
PNG
(CHEMBL402187)
Show SMILES C[C@@H]1CCCN1CCc1nc(oc1C)-c1ccccc1
Show InChI InChI=1S/C17H22N2O/c1-13-7-6-11-19(13)12-10-16-14(2)20-17(18-16)15-8-4-3-5-9-15/h3-5,8-9,13H,6-7,10-12H2,1-2H3/t13-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
62n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372323
PNG
(CHEMBL404532)
Show SMILES COc1ccc(CCN2CCC[C@@H]2C)cc1
Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
63n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372325
PNG
(CHEMBL272306)
Show SMILES COc1cccc(CCN2CCC[C@@H]2C)c1
Show InChI InChI=1S/C14H21NO/c1-12-5-4-9-15(12)10-8-13-6-3-7-14(11-13)16-2/h3,6-7,11-12H,4-5,8-10H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
65n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372311
PNG
(CHEMBL271722)
Show SMILES C[C@@H]1CCCN1CCc1ccncc1
Show InChI InChI=1S/C12H18N2/c1-11-3-2-9-14(11)10-6-12-4-7-13-8-5-12/h4-5,7-8,11H,2-3,6,9-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
70n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372305
PNG
(CHEMBL272141)
Show SMILES C[C@H]1CCCN1CCc1c(C)cc(C)cc1C
Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
72n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372339
PNG
(CHEMBL255141)
Show SMILES C[C@@H]1CCCN1CCc1ccns1
Show InChI InChI=1S/C10H16N2S/c1-9-3-2-7-12(9)8-5-10-4-6-11-13-10/h4,6,9H,2-3,5,7-8H2,1H3/t9-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
81n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372314
PNG
(CHEMBL257912)
Show SMILES Cc1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C13H19N/c1-12-4-6-13(7-5-12)8-11-14-9-2-3-10-14/h4-7H,2-3,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
81n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372296
PNG
(CHEMBL402377)
Show SMILES C[C@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
89n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372306
PNG
(CHEMBL408617)
Show SMILES C[C@H]1CCCN1CCc1ccccc1O
Show InChI InChI=1S/C13H19NO/c1-11-5-4-9-14(11)10-8-12-6-2-3-7-13(12)15/h2-3,6-7,11,15H,4-5,8-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
96n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372333
PNG
(CHEMBL440996)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C13H18N2O2/c1-11-3-2-9-14(11)10-8-12-4-6-13(7-5-12)15(16)17/h4-7,11H,2-3,8-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
96n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372299
PNG
(CHEMBL403736)
Show SMILES COc1ccc2[nH]c(CCN3CCC[C@@H]3C)cc2c1
Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
100n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372338
PNG
(CHEMBL271492)
Show SMILES C[C@H]1CCCN1CCc1cccs1
Show InChI InChI=1S/C11H17NS/c1-10-4-2-7-12(10)8-6-11-5-3-9-13-11/h3,5,9-10H,2,4,6-8H2,1H3/t10-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
110n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372302
PNG
(CHEMBL404375)
Show SMILES COc1ccccc1CCN1CCC[C@H]1C
Show InChI InChI=1S/C14H21NO/c1-12-6-5-10-15(12)11-9-13-7-3-4-8-14(13)16-2/h3-4,7-8,12H,5-6,9-11H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
110n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372320
PNG
(CHEMBL271252)
Show SMILES C[C@@H]1CCCN1CCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C15H20N2/c1-12-5-4-9-17(12)10-8-14-11-13-6-2-3-7-15(13)16-14/h2-3,6-7,11-12,16H,4-5,8-10H2,1H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
132n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372337
PNG
(CHEMBL402873)
Show SMILES C[C@@H]1CCCN1CCc1cccs1
Show InChI InChI=1S/C11H17NS/c1-10-4-2-7-12(10)8-6-11-5-3-9-13-11/h3,5,9-10H,2,4,6-8H2,1H3/t10-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
140n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372344
PNG
(CHEMBL405069)
Show SMILES C[C@H]1CCCN1CCc1ccncc1
Show InChI InChI=1S/C12H18N2/c1-11-3-2-9-14(11)10-6-12-4-7-13-8-5-12/h4-5,7-8,11H,2-3,6,9-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
140n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372310
PNG
(CHEMBL408259)
Show SMILES CCc1ccc(CCN2CCC[C@H]2C)nc1
Show InChI InChI=1S/C14H22N2/c1-3-13-6-7-14(15-11-13)8-10-16-9-4-5-12(16)2/h6-7,11-12H,3-5,8-10H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
150n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372343
PNG
(CHEMBL271300)
Show SMILES CCc1ccc(CCN2CCCC2)nc1
Show InChI InChI=1S/C13H20N2/c1-2-12-5-6-13(14-11-12)7-10-15-8-3-4-9-15/h5-6,11H,2-4,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
160n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372340
PNG
(CHEMBL406698)
Show SMILES C[C@H]1CCCN1CCc1ccns1
Show InChI InChI=1S/C10H16N2S/c1-9-3-2-7-12(9)8-5-10-4-6-11-13-10/h4,6,9H,2-3,5,7-8H2,1H3/t9-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
160n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372324
PNG
(CHEMBL439429)
Show SMILES COc1cccc(CCN2CCC[C@H]2C)c1
Show InChI InChI=1S/C14H21NO/c1-12-5-4-9-15(12)10-8-13-6-3-7-14(11-13)16-2/h3,6-7,11-12H,4-5,8-10H2,1-2H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
160n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372325
PNG
(CHEMBL272306)
Show SMILES COc1cccc(CCN2CCC[C@@H]2C)c1
Show InChI InChI=1S/C14H21NO/c1-12-5-4-9-15(12)10-8-13-6-3-7-14(11-13)16-2/h3,6-7,11-12H,4-5,8-10H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
170n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372341
PNG
(CHEMBL272131)
Show SMILES C(Cc1ccns1)N1CCCC1
Show InChI InChI=1S/C9H14N2S/c1-2-7-11(6-1)8-4-9-3-5-10-12-9/h3,5H,1-2,4,6-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
190n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372348
PNG
(CHEMBL270807)
Show SMILES C[C@@H]1CCCN1CCc1ccccn1
Show InChI InChI=1S/C12H18N2/c1-11-5-4-9-14(11)10-7-12-6-2-3-8-13-12/h2-3,6,8,11H,4-5,7,9-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
200n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372316
PNG
(CHEMBL257919)
Show SMILES Cc1cccc(CCN2CCCC2)c1
Show InChI InChI=1S/C13H19N/c1-12-5-4-6-13(11-12)7-10-14-8-2-3-9-14/h4-6,11H,2-3,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
200n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372317
PNG
(CHEMBL271237)
Show SMILES Cc1oc(nc1CCN1CCCC1)-c1ccccc1
Show InChI InChI=1S/C16H20N2O/c1-13-15(9-12-18-10-5-6-11-18)17-16(19-13)14-7-3-2-4-8-14/h2-4,7-8H,5-6,9-12H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
210n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372300
PNG
(CHEMBL271899)
Show SMILES C(Cc1cc2ccccc2[nH]1)N1CCCC1
Show InChI InChI=1S/C14H18N2/c1-2-6-14-12(5-1)11-13(15-14)7-10-16-8-3-4-9-16/h1-2,5-6,11,15H,3-4,7-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
219n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372306
PNG
(CHEMBL408617)
Show SMILES C[C@H]1CCCN1CCc1ccccc1O
Show InChI InChI=1S/C13H19NO/c1-11-5-4-9-14(11)10-8-12-6-2-3-7-13(12)15/h2-3,6-7,11,15H,4-5,8-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
220n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372336
PNG
(CHEMBL271489)
Show SMILES C[C@H]1CCCN1CCc1ccc(cc1)N(C)C
Show InChI InChI=1S/C15H24N2/c1-13-5-4-11-17(13)12-10-14-6-8-15(9-7-14)16(2)3/h6-9,13H,4-5,10-12H2,1-3H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
230n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372319
PNG
(CHEMBL403264)
Show SMILES COc1ccc2[nH]c(CCN3CCCC3)cc2c1
Show InChI InChI=1S/C15H20N2O/c1-18-14-4-5-15-12(11-14)10-13(16-15)6-9-17-7-2-3-8-17/h4-5,10-11,16H,2-3,6-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
230n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372343
PNG
(CHEMBL271300)
Show SMILES CCc1ccc(CCN2CCCC2)nc1
Show InChI InChI=1S/C13H20N2/c1-2-12-5-6-13(14-11-12)7-10-15-8-3-4-9-15/h5-6,11H,2-4,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
230n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372330
PNG
(CHEMBL272140)
Show SMILES Cc1cc(C)c(CCN2CCCC2)c(C)c1
Show InChI InChI=1S/C15H23N/c1-12-10-13(2)15(14(3)11-12)6-9-16-7-4-5-8-16/h10-11H,4-9H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
230n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372331
PNG
(CHEMBL404834)
Show SMILES C[C@@H]1CCCN1CCc1ccccc1O
Show InChI InChI=1S/C13H19NO/c1-11-5-4-9-14(11)10-8-12-6-2-3-7-13(12)15/h2-3,6-7,11,15H,4-5,8-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
240n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372327
PNG
(CHEMBL404912)
Show SMILES COc1ccccc1CCN1CCC[C@@H]1C
Show InChI InChI=1S/C14H21NO/c1-12-6-5-10-15(12)11-9-13-7-3-4-8-14(13)16-2/h3-4,7-8,12H,5-6,9-11H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
240n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372315
PNG
(CHEMBL257914)
Show SMILES C[C@H]1CCCN1CCc1cccc(C)c1
Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
240n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372293
PNG
(CHEMBL270410)
Show SMILES C(Cc1ccc2ccccc2c1)N1CCCC1
Show InChI InChI=1S/C16H19N/c1-2-6-16-13-14(7-8-15(16)5-1)9-12-17-10-3-4-11-17/h1-2,5-8,13H,3-4,9-12H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>240n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372326
PNG
(CHEMBL404911)
Show SMILES COc1cccc(CCN2CCCC2)c1
Show InChI InChI=1S/C13H19NO/c1-15-13-6-4-5-12(11-13)7-10-14-8-2-3-9-14/h4-6,11H,2-3,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
260n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372328
PNG
(CHEMBL257913)
Show SMILES COc1ccccc1CCN1CCCC1
Show InChI InChI=1S/C13H19NO/c1-15-13-7-3-2-6-12(13)8-11-14-9-4-5-10-14/h2-3,6-7H,4-5,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
260n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372334
PNG
(CHEMBL257235)
Show SMILES C[C@H]1CCCN1CCc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C13H18N2O2/c1-11-3-2-9-14(11)10-8-12-4-6-13(7-5-12)15(16)17/h4-7,11H,2-3,8-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
260n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372332
PNG
(CHEMBL273002)
Show SMILES Oc1ccccc1CCN1CCCC1
Show InChI InChI=1S/C12H17NO/c14-12-6-2-1-5-11(12)7-10-13-8-3-4-9-13/h1-2,5-6,14H,3-4,7-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
270n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372333
PNG
(CHEMBL440996)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C13H18N2O2/c1-11-3-2-9-14(11)10-8-12-4-6-13(7-5-12)15(16)17/h4-7,11H,2-3,8-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
280n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372346
PNG
(CHEMBL271226)
Show SMILES C[C@@H]1CCCN1CCc1cccnc1
Show InChI InChI=1S/C12H18N2/c1-11-4-3-8-14(11)9-6-12-5-2-7-13-10-12/h2,5,7,10-11H,3-4,6,8-9H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
300n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372342
PNG
(CHEMBL271504)
Show SMILES CCc1ccc(CCN2CCC[C@@H]2C)nc1
Show InChI InChI=1S/C14H22N2/c1-3-13-6-7-14(15-11-13)8-10-16-9-4-5-12(16)2/h6-7,11-12H,3-5,8-10H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
300n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372297
PNG
(CHEMBL272951)
Show SMILES C[C@H]1CCCN1CCc1cccnc1
Show InChI InChI=1S/C12H18N2/c1-11-4-3-8-14(11)9-6-12-5-2-7-13-10-12/h2,5,7,10-11H,3-4,6,8-9H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372346
PNG
(CHEMBL271226)
Show SMILES C[C@@H]1CCCN1CCc1cccnc1
Show InChI InChI=1S/C12H18N2/c1-11-4-3-8-14(11)9-6-12-5-2-7-13-10-12/h2,5,7,10-11H,3-4,6,8-9H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372344
PNG
(CHEMBL405069)
Show SMILES C[C@H]1CCCN1CCc1ccncc1
Show InChI InChI=1S/C12H18N2/c1-11-3-2-9-14(11)10-6-12-4-7-13-8-5-12/h4-5,7-8,11H,2-3,6,9-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372289
PNG
(CHEMBL270595)
Show SMILES C(Cc1ccccn1)N1CCCC1
Show InChI InChI=1S/C11H16N2/c1-2-7-12-11(5-1)6-10-13-8-3-4-9-13/h1-2,5,7H,3-4,6,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372341
PNG
(CHEMBL272131)
Show SMILES C(Cc1ccns1)N1CCCC1
Show InChI InChI=1S/C9H14N2S/c1-2-7-11(6-1)8-4-9-3-5-10-12-9/h3,5H,1-2,4,6-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372347
PNG
(CHEMBL272950)
Show SMILES C(Cc1cccnc1)N1CCCC1
Show InChI InChI=1S/C11H16N2/c1-2-8-13(7-1)9-5-11-4-3-6-12-10-11/h3-4,6,10H,1-2,5,7-9H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372311
PNG
(CHEMBL271722)
Show SMILES C[C@@H]1CCCN1CCc1ccncc1
Show InChI InChI=1S/C12H18N2/c1-11-3-2-9-14(11)10-6-12-4-7-13-8-5-12/h4-5,7-8,11H,2-3,6,9-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372342
PNG
(CHEMBL271504)
Show SMILES CCc1ccc(CCN2CCC[C@@H]2C)nc1
Show InChI InChI=1S/C14H22N2/c1-3-13-6-7-14(15-11-13)8-10-16-9-4-5-12(16)2/h6-7,11-12H,3-5,8-10H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372345
PNG
(CHEMBL405070)
Show SMILES C(Cc1ccncc1)N1CCCC1
Show InChI InChI=1S/C11H16N2/c1-2-9-13(8-1)10-5-11-3-6-12-7-4-11/h3-4,6-7H,1-2,5,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372348
PNG
(CHEMBL270807)
Show SMILES C[C@@H]1CCCN1CCc1ccccn1
Show InChI InChI=1S/C12H18N2/c1-11-5-4-9-14(11)10-7-12-6-2-3-8-13-12/h2-3,6,8,11H,4-5,7,9-10H2,1H3/t11-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>320n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372326
PNG
(CHEMBL404911)
Show SMILES COc1cccc(CCN2CCCC2)c1
Show InChI InChI=1S/C13H19NO/c1-15-13-6-4-5-12(11-13)7-10-14-8-2-3-9-14/h4-6,11H,2-3,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>330n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372313
PNG
(CHEMBL257911)
Show SMILES C[C@H]1CCCN1CCc1ccc(C)cc1
Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
330n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372297
PNG
(CHEMBL272951)
Show SMILES C[C@H]1CCCN1CCc1cccnc1
Show InChI InChI=1S/C12H18N2/c1-11-4-3-8-14(11)9-6-12-5-2-7-13-10-12/h2,5,7,10-11H,3-4,6,8-9H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>330n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372312
PNG
(CHEMBL429740)
Show SMILES C[C@H]1CCCN1CCc1ccccn1
Show InChI InChI=1S/C12H18N2/c1-11-5-4-9-14(11)10-7-12-6-2-3-8-13-12/h2-3,6,8,11H,4-5,7,9-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>330n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372312
PNG
(CHEMBL429740)
Show SMILES C[C@H]1CCCN1CCc1ccccn1
Show InChI InChI=1S/C12H18N2/c1-11-5-4-9-14(11)10-7-12-6-2-3-8-13-12/h2-3,6,8,11H,4-5,7,9-10H2,1H3/t11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372347
PNG
(CHEMBL272950)
Show SMILES C(Cc1cccnc1)N1CCCC1
Show InChI InChI=1S/C11H16N2/c1-2-8-13(7-1)9-5-11-4-3-6-12-10-11/h3-4,6,10H,1-2,5,7-9H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372309
PNG
(CHEMBL404835)
Show SMILES C(Cc1cccs1)N1CCCC1
Show InChI InChI=1S/C10H15NS/c1-2-7-11(6-1)8-5-10-4-3-9-12-10/h3-4,9H,1-2,5-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372300
PNG
(CHEMBL271899)
Show SMILES C(Cc1cc2ccccc2[nH]1)N1CCCC1
Show InChI InChI=1S/C14H18N2/c1-2-6-14-12(5-1)11-13(15-14)7-10-16-8-3-4-9-16/h1-2,5-6,11,15H,3-4,7-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372308
PNG
(CHEMBL271490)
Show SMILES CN(C)c1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C14H22N2/c1-15(2)14-7-5-13(6-8-14)9-12-16-10-3-4-11-16/h5-8H,3-4,9-12H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372321
PNG
(CHEMBL272988)
Show SMILES C[C@H]1CCCN1CCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C15H20N2/c1-12-5-4-9-17(12)10-8-14-11-13-6-2-3-7-15(13)16-14/h2-3,6-7,11-12,16H,4-5,8-10H2,1H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372320
PNG
(CHEMBL271252)
Show SMILES C[C@@H]1CCCN1CCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C15H20N2/c1-12-5-4-9-17(12)10-8-14-11-13-6-2-3-7-15(13)16-14/h2-3,6-7,11-12,16H,4-5,8-10H2,1H3/t12-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372328
PNG
(CHEMBL257913)
Show SMILES COc1ccccc1CCN1CCCC1
Show InChI InChI=1S/C13H19NO/c1-15-13-7-3-2-6-12(13)8-11-14-9-4-5-10-14/h2-3,6-7H,4-5,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372338
PNG
(CHEMBL271492)
Show SMILES C[C@H]1CCCN1CCc1cccs1
Show InChI InChI=1S/C11H17NS/c1-10-4-2-7-12(10)8-6-11-5-3-9-13-11/h3,5,9-10H,2,4,6-8H2,1H3/t10-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372316
PNG
(CHEMBL257919)
Show SMILES Cc1cccc(CCN2CCCC2)c1
Show InChI InChI=1S/C13H19N/c1-12-5-4-6-13(11-12)7-10-14-8-2-3-9-14/h4-6,11H,2-3,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372332
PNG
(CHEMBL273002)
Show SMILES Oc1ccccc1CCN1CCCC1
Show InChI InChI=1S/C12H17NO/c14-12-6-2-1-5-11(12)7-10-13-8-3-4-9-13/h1-2,5-6,14H,3-4,7-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372307
PNG
(CHEMBL273004)
Show SMILES [O-][N+](=O)c1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C12H16N2O2/c15-14(16)12-5-3-11(4-6-12)7-10-13-8-1-2-9-13/h3-6H,1-2,7-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372314
PNG
(CHEMBL257912)
Show SMILES Cc1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C13H19N/c1-12-4-6-13(7-5-12)8-11-14-9-2-3-10-14/h4-7H,2-3,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>340n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372289
PNG
(CHEMBL270595)
Show SMILES C(Cc1ccccn1)N1CCCC1
Show InChI InChI=1S/C11H16N2/c1-2-7-12-11(5-1)6-10-13-8-3-4-9-13/h1-2,5,7H,3-4,6,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>350n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372345
PNG
(CHEMBL405070)
Show SMILES C(Cc1ccncc1)N1CCCC1
Show InChI InChI=1S/C11H16N2/c1-2-9-13(8-1)10-5-11-3-6-12-7-4-11/h3-4,6-7H,1-2,5,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
350n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372319
PNG
(CHEMBL403264)
Show SMILES COc1ccc2[nH]c(CCN3CCCC3)cc2c1
Show InChI InChI=1S/C15H20N2O/c1-18-14-4-5-15-12(11-14)10-13(16-15)6-9-17-7-2-3-8-17/h4-5,10-11,16H,2-3,6-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>360n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372308
PNG
(CHEMBL271490)
Show SMILES CN(C)c1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C14H22N2/c1-15(2)14-7-5-13(6-8-14)9-12-16-10-3-4-11-16/h5-8H,3-4,9-12H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>360n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372307
PNG
(CHEMBL273004)
Show SMILES [O-][N+](=O)c1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C12H16N2O2/c15-14(16)12-5-3-11(4-6-12)7-10-13-8-1-2-9-13/h3-6H,1-2,7-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
360n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372309
PNG
(CHEMBL404835)
Show SMILES C(Cc1cccs1)N1CCCC1
Show InChI InChI=1S/C10H15NS/c1-2-7-11(6-1)8-5-10-4-3-9-12-10/h3-4,9H,1-2,5-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>360n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372299
PNG
(CHEMBL403736)
Show SMILES COc1ccc2[nH]c(CCN3CCC[C@@H]3C)cc2c1
Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>360n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372301
PNG
(CHEMBL272307)
Show SMILES COc1ccc(CCN2CCCC2)cc1
Show InChI InChI=1S/C13H19NO/c1-15-13-6-4-12(5-7-13)8-11-14-9-2-3-10-14/h4-7H,2-3,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
370n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50372330
PNG
(CHEMBL272140)
Show SMILES Cc1cc(C)c(CCN2CCCC2)c(C)c1
Show InChI InChI=1S/C15H23N/c1-12-10-13(2)15(14(3)11-12)6-9-16-7-4-5-8-16/h10-11H,4-9H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
400n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50372298
PNG
(CHEMBL402415)
Show SMILES C[C@H]1CCCN1CCc1nc(oc1C)-c1ccccc1
Show InChI InChI=1S/C17H22N2O/c1-13-7-6-11-19(13)12-10-16-14(2)20-17(18-16)15-8-4-3-5-9-15/h3-5,8-9,13H,6-7,10-12H2,1-2H3/t13-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
440n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50372295
PNG
(CHEMBL429914)
Show SMILES C[C@@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H4 receptor by [35S]GTP-gamma-S binding assay


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50372296
PNG
(CHEMBL402377)
Show SMILES C[C@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H1 receptor by [35S]GTP-gamma-S binding assay


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H2 Receptor


(Homo sapiens (Human))
BDBM50372296
PNG
(CHEMBL402377)
Show SMILES C[C@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H2 receptor by [35S]GTP-gamma-S binding assay


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50372295
PNG
(CHEMBL429914)
Show SMILES C[C@@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H1 receptor by [35S]GTP-gamma-S binding assay


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50372296
PNG
(CHEMBL402377)
Show SMILES C[C@H]1CCCN1CCc1ccc2ccccc2c1
Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H4 receptor by [35S]GTP-gamma-S binding assay


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
Histamine H2 Receptor


(Homo sapiens (Human))
BDBM50372295
PNG
(CHEMBL429914)
Show SMILES C[C@@H]1CCCN1CCc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at histamine H2 receptor by [35S]GTP-gamma-S binding assay


Bioorg Med Chem Lett 18: 355-9 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.067
BindingDB Entry DOI: 10.7270/Q2VM4D4V
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%