Affinity Data by PubMed id=22482720

PubMed code 22482720

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM92753 (2,6-Dichlorophenol \| 2,6-Dichlorophenol (2,6-DCP)) Show SMILES Oc1c(Cl)cccc1Cl Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	4.55E+4	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM36301 (2-Chlorophenol (2-CP) \| 2-chlorophenol) Show SMILES Oc1ccccc1Cl Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM92749 (Pentachlorophenol (PCP)) Show SMILES Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM92754 (3,5-Dichlorphenol (3,5-DCP)) Show SMILES Oc1cc(Cl)cc(Cl)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM92751 (Tetrachlorohydroquinone (TCHQ)) Show SMILES Oc1c(Cl)c(Cl)c(O)c(Cl)c1Cl Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM92752 (2,4,6-Trichlorophenol (2,4,6-TriCP)) Show SMILES Oc1c(Cl)cc(Cl)cc1Cl Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM91350 (3,4,5-trichlorophenol \| 3,4,5-tris(chloranyl)pheno...) Show SMILES Oc1cc(Cl)c(Cl)c(Cl)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair
Pentachlorophenol 4-monooxygenase (Sphingobium chlorophenolicum)	BDBM92750 (2,3,4,6-Tetrachlorophenol (TCP)) Show SMILES Oc1c(Cl)c(Cl)cc(Cl)c1Cl Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a
University of Colorado Boulder					Assay Description Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.				Biochemistry 51: 3848-60 (2012) Article DOI: 10.1021/bi300261p BindingDB Entry DOI: 10.7270/Q24T6H0M
University of Colorado Boulder					More data for this Ligand-Target Pair

* indicates data uncertainty>20%