Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM21130
(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
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MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50000296
(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
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CHEMBL
KEGG
PC cid
PC sid
UniChem
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| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 4.63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101309
(CHEMBL3326360)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(OC)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C21H23NO5/c1-20(14-7-5-9-16(11-14)24-3)18-22-17(12-25-18)26-21(2,19(22)27-20)13-6-4-8-15(23)10-13/h4-11,17-19,23H,12H2,1-3H3/t17-,18-,19-,20+,21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101314
(CHEMBL3326355)Show SMILES CC1(OC2N3C(COC13)OC2(C)c1cccc(O)c1)c1cccc(O)c1 Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 293 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101314
(CHEMBL3326355)Show SMILES CC1(OC2N3C(COC13)OC2(C)c1cccc(O)c1)c1cccc(O)c1 Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 651 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101326
(CHEMBL3326350)Show SMILES [H][C@]12O[C@@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26-,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 652 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101326
(CHEMBL3326350)Show SMILES [H][C@]12O[C@@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26-,27+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 667 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101316
(CHEMBL3326352)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19-,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 735 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101316
(CHEMBL3326352)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19-,20-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 793 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101325
(CHEMBL3326351)Show SMILES [H][C@]12O[C@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 928 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101313
(CHEMBL3326356)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101308
(CHEMBL3326361)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(OC)c1 |r| Show InChI InChI=1S/C21H23NO5/c1-20(13-6-4-8-15(23)10-13)18-22-17(12-25-18)26-21(2,19(22)27-20)14-7-5-9-16(11-14)24-3/h4-11,17-19,23H,12H2,1-3H3/t17-,18-,19-,20+,21-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101326
(CHEMBL3326350)Show SMILES [H][C@]12O[C@@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26-,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50000296
(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM21130
(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101314
(CHEMBL3326355)Show SMILES CC1(OC2N3C(COC13)OC2(C)c1cccc(O)c1)c1cccc(O)c1 Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101308
(CHEMBL3326361)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(OC)c1 |r| Show InChI InChI=1S/C21H23NO5/c1-20(13-6-4-8-15(23)10-13)18-22-17(12-25-18)26-21(2,19(22)27-20)14-7-5-9-16(11-14)24-3/h4-11,17-19,23H,12H2,1-3H3/t17-,18-,19-,20+,21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101327
(CHEMBL3326349)Show SMILES [H][C@]12O[C@@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26-,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101315
(CHEMBL3326353)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@@]3(C)c1cccc(O)c1)[C@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19-,20+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101313
(CHEMBL3326356)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101310
(CHEMBL3326359)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(OC)c1)[C@@](C)(O2)c1cccc(OC)c1 |r| Show InChI InChI=1S/C22H25NO5/c1-21(14-7-5-9-16(11-14)24-3)19-23-18(13-26-19)27-22(2,20(23)28-21)15-8-6-10-17(12-15)25-4/h5-12,18-20H,13H2,1-4H3/t18-,19-,20-,21+,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101310
(CHEMBL3326359)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(OC)c1)[C@@](C)(O2)c1cccc(OC)c1 |r| Show InChI InChI=1S/C22H25NO5/c1-21(14-7-5-9-16(11-14)24-3)19-23-18(13-26-19)27-22(2,20(23)28-21)15-8-6-10-17(12-15)25-4/h5-12,18-20H,13H2,1-4H3/t18-,19-,20-,21+,22-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101309
(CHEMBL3326360)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(OC)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C21H23NO5/c1-20(14-7-5-9-16(11-14)24-3)18-22-17(12-25-18)26-21(2,19(22)27-20)13-6-4-8-15(23)10-13/h4-11,17-19,23H,12H2,1-3H3/t17-,18-,19-,20+,21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101327
(CHEMBL3326349)Show SMILES [H][C@]12O[C@@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26-,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101315
(CHEMBL3326353)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@@]3(C)c1cccc(O)c1)[C@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19-,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101327
(CHEMBL3326349)Show SMILES [H][C@]12O[C@@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26-,27-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101313
(CHEMBL3326356)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101315
(CHEMBL3326353)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@@]3(C)c1cccc(O)c1)[C@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19-,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50000296
(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101312
(CHEMBL3326357)Show SMILES [H][C@]12CO[C@]3([H])N1[C@]([H])(CO2)O[C@@]3(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-13(8-3-2-4-9(15)5-8)12-14-10(6-17-12)16-7-11(14)18-13/h2-5,10-12,15H,6-7H2,1H3/t10-,11-,12-,13-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM21130
(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101316
(CHEMBL3326352)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19-,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101325
(CHEMBL3326351)Show SMILES [H][C@]12O[C@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26+,27+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101308
(CHEMBL3326361)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(OC)c1 |r| Show InChI InChI=1S/C21H23NO5/c1-20(13-6-4-8-15(23)10-13)18-22-17(12-25-18)26-21(2,19(22)27-20)14-7-5-9-16(11-14)24-3/h4-11,17-19,23H,12H2,1-3H3/t17-,18-,19-,20+,21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101310
(CHEMBL3326359)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(OC)c1)[C@@](C)(O2)c1cccc(OC)c1 |r| Show InChI InChI=1S/C22H25NO5/c1-21(14-7-5-9-16(11-14)24-3)19-23-18(13-26-19)27-22(2,20(23)28-21)15-8-6-10-17(12-15)25-4/h5-12,18-20H,13H2,1-4H3/t18-,19-,20-,21+,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101312
(CHEMBL3326357)Show SMILES [H][C@]12CO[C@]3([H])N1[C@]([H])(CO2)O[C@@]3(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-13(8-3-2-4-9(15)5-8)12-14-10(6-17-12)16-7-11(14)18-13/h2-5,10-12,15H,6-7H2,1H3/t10-,11-,12-,13-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101311
(CHEMBL3326358)Show SMILES [H][C@]12CO[C@]3([H])N1[C@]([H])(CO2)O[C@]3(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-13(8-3-2-4-9(15)5-8)12-14-10(6-17-12)16-7-11(14)18-13/h2-5,10-12,15H,6-7H2,1H3/t10-,11-,12-,13+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50101325
(CHEMBL3326351)Show SMILES [H][C@]12O[C@](C)(c3cccc(O)c3)[C@]3([H])O[C@@](C)(c4cccc(O)c4)[C@]([H])(O[C@]1(C)c1cccc(O)c1)N23 |r| Show InChI InChI=1S/C27H27NO6/c1-25(16-7-4-10-19(29)13-16)22-28-23(32-25)26(2,17-8-5-11-20(30)14-17)34-24(28)27(3,33-22)18-9-6-12-21(31)15-18/h4-15,22-24,29-31H,1-3H3/t22-,23-,24-,25-,26+,27+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101311
(CHEMBL3326358)Show SMILES [H][C@]12CO[C@]3([H])N1[C@]([H])(CO2)O[C@]3(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-13(8-3-2-4-9(15)5-8)12-14-10(6-17-12)16-7-11(14)18-13/h2-5,10-12,15H,6-7H2,1H3/t10-,11-,12-,13+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(MOUSE) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101309
(CHEMBL3326360)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(OC)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C21H23NO5/c1-20(14-7-5-9-16(11-14)24-3)18-22-17(12-25-18)26-21(2,19(22)27-20)13-6-4-8-15(23)10-13/h4-11,17-19,23H,12H2,1-3H3/t17-,18-,19-,20+,21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101311
(CHEMBL3326358)Show SMILES [H][C@]12CO[C@]3([H])N1[C@]([H])(CO2)O[C@]3(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-13(8-3-2-4-9(15)5-8)12-14-10(6-17-12)16-7-11(14)18-13/h2-5,10-12,15H,6-7H2,1H3/t10-,11-,12-,13+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50101312
(CHEMBL3326357)Show SMILES [H][C@]12CO[C@]3([H])N1[C@]([H])(CO2)O[C@@]3(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-13(8-3-2-4-9(15)5-8)12-14-10(6-17-12)16-7-11(14)18-13/h2-5,10-12,15H,6-7H2,1H3/t10-,11-,12-,13-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 50.3 | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM21130
(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50101307
(CHEMBL3326354)Show SMILES [H][C@]12CO[C@]3([H])N1[C@@]([H])(O[C@]3(C)c1cccc(O)c1)[C@@](C)(O2)c1cccc(O)c1 |r| Show InChI InChI=1S/C20H21NO5/c1-19(12-5-3-7-14(22)9-12)17-21-16(11-24-17)25-20(2,18(21)26-19)13-6-4-8-15(23)10-13/h3-10,16-18,22-23H,11H2,1-2H3/t16-,17-,18-,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 84 | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding |
ACS Med Chem Lett 5: 868-72 (2014)
Article DOI: 10.1021/ml5000542
BindingDB Entry DOI: 10.7270/Q218388Q |
More data for this
Ligand-Target Pair | |
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