Found 66 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110470
(CHEMBL3605798)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCCc1ccccc1 Show InChI InChI=1S/C24H29N3/c1-19-11-13-21(14-12-19)22-18-25-23(27-22)24(15-5-6-16-24)26-17-7-10-20-8-3-2-4-9-20/h2-4,8-9,11-14,18,26H,5-7,10,15-17H2,1H3,(H,25,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110461
(CHEMBL3605789)Show SMILES Fc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C23H23FN4/c24-18-9-7-16(8-10-18)21-15-26-22(28-21)23(11-3-4-12-23)27-14-17-13-25-20-6-2-1-5-19(17)20/h1-2,5-10,13,15,25,27H,3-4,11-12,14H2,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110440
(CHEMBL3605785)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C24H26N4/c1-17-8-10-18(11-9-17)22-16-26-23(28-22)24(12-4-5-13-24)27-15-19-14-25-21-7-3-2-6-20(19)21/h2-3,6-11,14,16,25,27H,4-5,12-13,15H2,1H3,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110467
(CHEMBL3605795)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cc2ccccc2[nH]1 Show InChI InChI=1S/C24H26N4/c1-17-8-10-18(11-9-17)22-16-25-23(28-22)24(12-4-5-13-24)26-15-20-14-19-6-2-3-7-21(19)27-20/h2-3,6-11,14,16,26-27H,4-5,12-13,15H2,1H3,(H,25,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110441
(CHEMBL3605786)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C25H28N4/c1-18-9-11-19(12-10-18)23-17-27-24(29-23)25(13-5-2-6-14-25)28-16-20-15-26-22-8-4-3-7-21(20)22/h3-4,7-12,15,17,26,28H,2,5-6,13-14,16H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110460
(CHEMBL3605788)Show SMILES C(NC1(CCCC1)c1nc(c[nH]1)-c1ccccc1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H24N4/c1-2-8-17(9-3-1)21-16-25-22(27-21)23(12-6-7-13-23)26-15-18-14-24-20-11-5-4-10-19(18)20/h1-5,8-11,14,16,24,26H,6-7,12-13,15H2,(H,25,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110477
(CHEMBL3605805)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(F)cc1 Show InChI InChI=1S/C22H24FN3/c1-16-4-8-18(9-5-16)20-15-24-21(26-20)22(12-2-3-13-22)25-14-17-6-10-19(23)11-7-17/h4-11,15,25H,2-3,12-14H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110466
(CHEMBL3605794)Show SMILES COc1cccc2c(CNC3(CCCC3)c3nc(c[nH]3)-c3ccc(C)cc3)c[nH]c12 Show InChI InChI=1S/C25H28N4O/c1-17-8-10-18(11-9-17)21-16-27-24(29-21)25(12-3-4-13-25)28-15-19-14-26-23-20(19)6-5-7-22(23)30-2/h5-11,14,16,26,28H,3-4,12-13,15H2,1-2H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110465
(CHEMBL3605793)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2cccnc12 Show InChI InChI=1S/C23H25N5/c1-16-6-8-17(9-7-16)20-15-26-22(28-20)23(10-2-3-11-23)27-14-18-13-25-19-5-4-12-24-21(18)19/h4-9,12-13,15,25,27H,2-3,10-11,14H2,1H3,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110463
(CHEMBL3605791)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H28N4/c1-18-9-11-19(12-10-18)22-16-26-24(28-22)25(13-5-6-14-25)27-15-20-17-29(2)23-8-4-3-7-21(20)23/h3-4,7-12,16-17,27H,5-6,13-15H2,1-2H3,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110490
(CHEMBL3605812)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCC1CCCCC1 Show InChI InChI=1S/C22H31N3/c1-17-9-11-19(12-10-17)20-16-23-21(25-20)22(13-5-6-14-22)24-15-18-7-3-2-4-8-18/h9-12,16,18,24H,2-8,13-15H2,1H3,(H,23,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110462
(CHEMBL3605790)Show SMILES C(NC1(CCCC1)c1nc(c[nH]1)-c1ccc(cc1)-c1ccccc1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C29H28N4/c1-2-8-21(9-3-1)22-12-14-23(15-13-22)27-20-31-28(33-27)29(16-6-7-17-29)32-19-24-18-30-26-11-5-4-10-25(24)26/h1-5,8-15,18,20,30,32H,6-7,16-17,19H2,(H,31,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110474
(CHEMBL3605802)Show SMILES COc1ccc(CNC2(CCCC2)c2nc(c[nH]2)-c2ccc(C)cc2)cc1 Show InChI InChI=1S/C23H27N3O/c1-17-5-9-19(10-6-17)21-16-24-22(26-21)23(13-3-4-14-23)25-15-18-7-11-20(27-2)12-8-18/h5-12,16,25H,3-4,13-15H2,1-2H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110475
(CHEMBL3605803)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClN3/c1-16-4-8-18(9-5-16)20-15-24-21(26-20)22(12-2-3-13-22)25-14-17-6-10-19(23)11-7-17/h4-11,15,25H,2-3,12-14H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110472
(CHEMBL3605800)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCC(C)(C)C Show InChI InChI=1S/C21H31N3/c1-16-7-9-17(10-8-16)18-15-22-19(24-18)21(11-5-6-12-21)23-14-13-20(2,3)4/h7-10,15,23H,5-6,11-14H2,1-4H3,(H,22,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110469
(CHEMBL3605797)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCc1ccccc1 Show InChI InChI=1S/C23H27N3/c1-18-9-11-20(12-10-18)21-17-24-22(26-21)23(14-5-6-15-23)25-16-13-19-7-3-2-4-8-19/h2-4,7-12,17,25H,5-6,13-16H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110439
(CHEMBL3605784)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C23H24N4/c1-16-7-9-17(10-8-16)21-15-25-22(27-21)23(11-4-12-23)26-14-18-13-24-20-6-3-2-5-19(18)20/h2-3,5-10,13,15,24,26H,4,11-12,14H2,1H3,(H,25,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110459
(CHEMBL3605787)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCNCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C24H27N5/c1-17-6-8-18(9-7-17)22-16-27-23(29-22)24(10-12-25-13-11-24)28-15-19-14-26-21-5-3-2-4-20(19)21/h2-9,14,16,25-26,28H,10-13,15H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110478
(CHEMBL3605806)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cccc(F)c1 Show InChI InChI=1S/C22H24FN3/c1-16-7-9-18(10-8-16)20-15-24-21(26-20)22(11-2-3-12-22)25-14-17-5-4-6-19(23)13-17/h4-10,13,15,25H,2-3,11-12,14H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110464
(CHEMBL3605792)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C25H28N4/c1-18-8-10-19(11-9-18)23-17-27-24(29-23)25(13-4-5-14-25)28-15-12-20-16-26-22-7-3-2-6-21(20)22/h2-3,6-11,16-17,26,28H,4-5,12-15H2,1H3,(H,27,29) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110468
(CHEMBL3605796)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccccc1 Show InChI InChI=1S/C22H25N3/c1-17-9-11-19(12-10-17)20-16-23-21(25-20)22(13-5-6-14-22)24-15-18-7-3-2-4-8-18/h2-4,7-12,16,24H,5-6,13-15H2,1H3,(H,23,25) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110488
(CHEMBL3605810)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H29N3/c1-21-9-13-25(14-10-21)26-20-29-27(31-26)28(17-5-6-18-28)30-19-22-11-15-24(16-12-22)23-7-3-2-4-8-23/h2-4,7-16,20,30H,5-6,17-19H2,1H3,(H,29,31) | Reactome pathway
KEGG
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antibodypedia
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PC sid
UniChem
Similars
| Article
PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110437
(CHEMBL3605782)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C(C)(C)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C22H24N4/c1-15-8-10-16(11-9-15)20-14-24-21(26-20)22(2,3)25-13-17-12-23-19-7-5-4-6-18(17)19/h4-12,14,23,25H,13H2,1-3H3,(H,24,26) | Reactome pathway
KEGG
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PC sid
UniChem
Patents
Similars
| Article
PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110476
(CHEMBL3605804)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N3/c1-16-4-8-18(9-5-16)20-15-27-21(29-20)22(12-2-3-13-22)28-14-17-6-10-19(11-7-17)23(24,25)26/h4-11,15,28H,2-3,12-14H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
Similars
| Article
PubMed
| 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110471
(CHEMBL3605799)Show InChI InChI=1S/C18H25N3/c1-3-12-20-18(10-4-5-11-18)17-19-13-16(21-17)15-8-6-14(2)7-9-15/h6-9,13,20H,3-5,10-12H2,1-2H3,(H,19,21) | Reactome pathway
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110487
(CHEMBL3605809)Show SMILES COC(=O)c1ccc(CNC2(CCCC2)c2nc(c[nH]2)-c2ccc(C)cc2)cc1 Show InChI InChI=1S/C24H27N3O2/c1-17-5-9-19(10-6-17)21-16-25-23(27-21)24(13-3-4-14-24)26-15-18-7-11-20(12-8-18)22(28)29-2/h5-12,16,26H,3-4,13-15H2,1-2H3,(H,25,27) | Reactome pathway
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| 830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110491
(CHEMBL3605813)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCC1CCOCC1 Show InChI InChI=1S/C21H29N3O/c1-16-4-6-18(7-5-16)19-15-22-20(24-19)21(10-2-3-11-21)23-14-17-8-12-25-13-9-17/h4-7,15,17,23H,2-3,8-14H2,1H3,(H,22,24) | Reactome pathway
KEGG
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PC sid
UniChem
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Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110489
(CHEMBL3605811)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc2ncccc2c1 Show InChI InChI=1S/C25H26N4/c1-18-6-9-20(10-7-18)23-17-27-24(29-23)25(12-2-3-13-25)28-16-19-8-11-22-21(15-19)5-4-14-26-22/h4-11,14-15,17,28H,2-3,12-13,16H2,1H3,(H,27,29) | Reactome pathway
KEGG
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UniChem
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110438
(CHEMBL3605783)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C22H22N4/c1-15-6-8-16(9-7-15)20-14-24-21(26-20)22(10-11-22)25-13-17-12-23-19-5-3-2-4-18(17)19/h2-9,12,14,23,25H,10-11,13H2,1H3,(H,24,26) | Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110473
(CHEMBL3605801)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCC(F)(F)F Show InChI InChI=1S/C18H22F3N3/c1-13-4-6-14(7-5-13)15-12-22-16(24-15)17(8-2-3-9-17)23-11-10-18(19,20)21/h4-7,12,23H,2-3,8-11H2,1H3,(H,22,24) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110492
(CHEMBL3605814)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cnn(C)c1 Show InChI InChI=1S/C20H25N5/c1-15-5-7-17(8-6-15)18-13-21-19(24-18)20(9-3-4-10-20)22-11-16-12-23-25(2)14-16/h5-8,12-14,22H,3-4,9-11H2,1-2H3,(H,21,24) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110479
(CHEMBL3605807)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccncc1 Show InChI InChI=1S/C21H24N4/c1-16-4-6-18(7-5-16)19-15-23-20(25-19)21(10-2-3-11-21)24-14-17-8-12-22-13-9-17/h4-9,12-13,15,24H,2-3,10-11,14H2,1H3,(H,23,25) | Reactome pathway
KEGG
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| CHEMBL
PC cid
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UniChem
Similars
| Article
PubMed
| 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110493
(CHEMBL3605815)Show SMILES CCn1cncc1CNC1(CCCC1)c1nc(c[nH]1)-c1ccc(C)cc1 Show InChI InChI=1S/C21H27N5/c1-3-26-15-22-12-18(26)13-24-21(10-4-5-11-21)20-23-14-19(25-20)17-8-6-16(2)7-9-17/h6-9,12,14-15,24H,3-5,10-11,13H2,1-2H3,(H,23,25) | Reactome pathway
KEGG
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PC sid
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Similars
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PubMed
| 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells after 60 to 90 mins |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110461
(CHEMBL3605789)Show SMILES Fc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C23H23FN4/c24-18-9-7-16(8-10-18)21-15-26-22(28-21)23(11-3-4-12-23)27-14-17-13-25-20-6-2-1-5-19(17)20/h1-2,5-10,13,15,25,27H,3-4,11-12,14H2,(H,26,28) | Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110470
(CHEMBL3605798)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCCc1ccccc1 Show InChI InChI=1S/C24H29N3/c1-19-11-13-21(14-12-19)22-18-25-23(27-22)24(15-5-6-16-24)26-17-7-10-20-8-3-2-4-9-20/h2-4,8-9,11-14,18,26H,5-7,10,15-17H2,1H3,(H,25,27) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110474
(CHEMBL3605802)Show SMILES COc1ccc(CNC2(CCCC2)c2nc(c[nH]2)-c2ccc(C)cc2)cc1 Show InChI InChI=1S/C23H27N3O/c1-17-5-9-19(10-6-17)21-16-24-22(26-21)23(13-3-4-14-23)25-15-18-7-11-20(27-2)12-8-18/h5-12,16,25H,3-4,13-15H2,1-2H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 96 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110473
(CHEMBL3605801)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCC(F)(F)F Show InChI InChI=1S/C18H22F3N3/c1-13-4-6-14(7-5-13)15-12-22-16(24-15)17(8-2-3-9-17)23-11-10-18(19,20)21/h4-7,12,23H,2-3,8-11H2,1H3,(H,22,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110491
(CHEMBL3605813)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCC1CCOCC1 Show InChI InChI=1S/C21H29N3O/c1-16-4-6-18(7-5-16)19-15-22-20(24-19)21(10-2-3-11-21)23-14-17-8-12-25-13-9-17/h4-7,15,17,23H,2-3,8-14H2,1H3,(H,22,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110437
(CHEMBL3605782)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C(C)(C)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C22H24N4/c1-15-8-10-16(11-9-15)20-14-24-21(26-20)22(2,3)25-13-17-12-23-19-7-5-4-6-18(17)19/h4-12,14,23,25H,13H2,1-3H3,(H,24,26) | Reactome pathway
KEGG
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| Article
PubMed
| n/a | n/a | n/a | n/a | 390 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110466
(CHEMBL3605794)Show SMILES COc1cccc2c(CNC3(CCCC3)c3nc(c[nH]3)-c3ccc(C)cc3)c[nH]c12 Show InChI InChI=1S/C25H28N4O/c1-17-8-10-18(11-9-17)21-16-27-24(29-21)25(12-3-4-13-25)28-15-19-14-26-23-20(19)6-5-7-22(23)30-2/h5-11,14,16,26,28H,3-4,12-13,15H2,1-2H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110494
(CHEMBL3605808)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cncnc1 Show InChI InChI=1S/C20H23N5/c1-15-4-6-17(7-5-15)18-13-23-19(25-18)20(8-2-3-9-20)24-12-16-10-21-14-22-11-16/h4-7,10-11,13-14,24H,2-3,8-9,12H2,1H3,(H,23,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110488
(CHEMBL3605810)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H29N3/c1-21-9-13-25(14-10-21)26-20-29-27(31-26)28(17-5-6-18-28)30-19-22-11-15-24(16-12-22)23-7-3-2-4-8-23/h2-4,7-16,20,30H,5-6,17-19H2,1H3,(H,29,31) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110489
(CHEMBL3605811)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc2ncccc2c1 Show InChI InChI=1S/C25H26N4/c1-18-6-9-20(10-7-18)23-17-27-24(29-23)25(12-2-3-13-25)28-16-19-8-11-22-21(15-19)5-4-14-26-22/h4-11,14-15,17,28H,2-3,12-13,16H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110492
(CHEMBL3605814)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cnn(C)c1 Show InChI InChI=1S/C20H25N5/c1-15-5-7-17(8-6-15)18-13-21-19(24-18)20(9-3-4-10-20)22-11-16-12-23-25(2)14-16/h5-8,12-14,22H,3-4,9-11H2,1-2H3,(H,21,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110439
(CHEMBL3605784)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C23H24N4/c1-16-7-9-17(10-8-16)21-15-25-22(27-21)23(11-4-12-23)26-14-18-13-24-20-6-3-2-5-19(18)20/h2-3,5-10,13,15,24,26H,4,11-12,14H2,1H3,(H,25,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110441
(CHEMBL3605786)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C25H28N4/c1-18-9-11-19(12-10-18)23-17-27-24(29-23)25(13-5-2-6-14-25)28-16-20-15-26-22-8-4-3-7-21(20)22/h3-4,7-12,15,17,26,28H,2,5-6,13-14,16H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110471
(CHEMBL3605799)Show InChI InChI=1S/C18H25N3/c1-3-12-20-18(10-4-5-11-18)17-19-13-16(21-17)15-8-6-14(2)7-9-15/h6-9,13,20H,3-5,10-12H2,1-2H3,(H,19,21) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 770 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110487
(CHEMBL3605809)Show SMILES COC(=O)c1ccc(CNC2(CCCC2)c2nc(c[nH]2)-c2ccc(C)cc2)cc1 Show InChI InChI=1S/C24H27N3O2/c1-17-5-9-19(10-6-17)21-16-25-23(27-21)24(13-3-4-14-24)26-15-18-7-11-20(12-8-18)22(28)29-2/h5-12,16,26H,3-4,13-15H2,1-2H3,(H,25,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 970 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110490
(CHEMBL3605812)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCC1CCCCC1 Show InChI InChI=1S/C22H31N3/c1-17-9-11-19(12-10-17)20-16-23-21(25-20)22(13-5-6-14-22)24-15-18-7-3-2-4-8-18/h9-12,16,18,24H,2-8,13-15H2,1H3,(H,23,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110493
(CHEMBL3605815)Show SMILES CCn1cncc1CNC1(CCCC1)c1nc(c[nH]1)-c1ccc(C)cc1 Show InChI InChI=1S/C21H27N5/c1-3-26-15-22-12-18(26)13-24-21(10-4-5-11-21)20-23-14-19(25-20)17-8-6-16(2)7-9-17/h6-9,12,14-15,24H,3-5,10-11,13H2,1-2H3,(H,23,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110460
(CHEMBL3605788)Show SMILES C(NC1(CCCC1)c1nc(c[nH]1)-c1ccccc1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H24N4/c1-2-8-17(9-3-1)21-16-25-22(27-21)23(12-6-7-13-23)26-15-18-14-24-20-11-5-4-10-19(18)20/h1-5,8-11,14,16,24,26H,6-7,12-13,15H2,(H,25,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110465
(CHEMBL3605793)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2cccnc12 Show InChI InChI=1S/C23H25N5/c1-16-6-8-17(9-7-16)20-15-26-22(28-20)23(10-2-3-11-23)27-14-18-13-25-19-5-4-12-24-21(18)19/h4-9,12-13,15,25,27H,2-3,10-11,14H2,1H3,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110472
(CHEMBL3605800)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCC(C)(C)C Show InChI InChI=1S/C21H31N3/c1-16-7-9-17(10-8-16)18-15-22-19(24-18)21(11-5-6-12-21)23-14-13-20(2,3)4/h7-10,15,23H,5-6,11-14H2,1-4H3,(H,22,24) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110476
(CHEMBL3605804)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H24F3N3/c1-16-4-8-18(9-5-16)20-15-27-21(29-20)22(12-2-3-13-22)28-14-17-6-10-19(11-7-17)23(24,25)26/h4-11,15,28H,2-3,12-14H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110469
(CHEMBL3605797)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCc1ccccc1 Show InChI InChI=1S/C23H27N3/c1-18-9-11-20(12-10-18)21-17-24-22(26-21)23(14-5-6-15-23)25-16-13-19-7-3-2-4-8-19/h2-4,7-12,17,25H,5-6,13-16H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 103 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110477
(CHEMBL3605805)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(F)cc1 Show InChI InChI=1S/C22H24FN3/c1-16-4-8-18(9-5-16)20-15-24-21(26-20)22(12-2-3-13-22)25-14-17-6-10-19(23)11-7-17/h4-11,15,25H,2-3,12-14H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110478
(CHEMBL3605806)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cccc(F)c1 Show InChI InChI=1S/C22H24FN3/c1-16-7-9-18(10-8-16)20-15-24-21(26-20)22(11-2-3-12-22)25-14-17-5-4-6-19(23)13-17/h4-10,13,15,25H,2-3,11-12,14H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 93 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110463
(CHEMBL3605791)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cn(C)c2ccccc12 Show InChI InChI=1S/C25H28N4/c1-18-9-11-19(12-10-18)22-16-26-24(28-22)25(13-5-6-14-25)27-15-20-17-29(2)23-8-4-3-7-21(20)23/h3-4,7-12,16-17,27H,5-6,13-15H2,1-2H3,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 54 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110468
(CHEMBL3605796)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccccc1 Show InChI InChI=1S/C22H25N3/c1-17-9-11-19(12-10-17)20-16-23-21(25-20)22(13-5-6-14-22)24-15-18-7-3-2-4-8-18/h2-4,7-12,16,24H,5-6,13-15H2,1H3,(H,23,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 61 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110475
(CHEMBL3605803)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClN3/c1-16-4-8-18(9-5-16)20-15-24-21(26-20)22(12-2-3-13-22)25-14-17-6-10-19(23)11-7-17/h4-11,15,25H,2-3,12-14H2,1H3,(H,24,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110479
(CHEMBL3605807)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1ccncc1 Show InChI InChI=1S/C21H24N4/c1-16-4-6-18(7-5-16)19-15-23-20(25-19)21(10-2-3-11-21)24-14-17-8-12-22-13-9-17/h4-9,12-13,15,24H,2-3,10-11,14H2,1H3,(H,23,25) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110440
(CHEMBL3605785)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C24H26N4/c1-17-8-10-18(11-9-17)22-16-26-23(28-22)24(12-4-5-13-24)27-15-19-14-25-21-7-3-2-6-20(19)21/h2-3,6-11,14,16,25,27H,4-5,12-13,15H2,1H3,(H,26,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110459
(CHEMBL3605787)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCNCC1)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C24H27N5/c1-17-6-8-18(9-7-17)22-16-27-23(29-22)24(10-12-25-13-11-24)28-15-19-14-26-21-5-3-2-4-20(19)21/h2-9,14,16,25-26,28H,10-13,15H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110462
(CHEMBL3605790)Show SMILES C(NC1(CCCC1)c1nc(c[nH]1)-c1ccc(cc1)-c1ccccc1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C29H28N4/c1-2-8-21(9-3-1)22-12-14-23(15-13-22)27-20-31-28(33-27)29(16-6-7-17-29)32-19-24-18-30-26-11-5-4-10-25(24)26/h1-5,8-15,18,20,30,32H,6-7,16-17,19H2,(H,31,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110464
(CHEMBL3605792)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C25H28N4/c1-18-8-10-19(11-9-18)23-17-27-24(29-23)25(13-4-5-14-25)28-15-12-20-16-26-22-7-3-2-6-21(20)22/h2-3,6-11,16-17,26,28H,4-5,12-15H2,1H3,(H,27,29) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50110467
(CHEMBL3605795)Show SMILES Cc1ccc(cc1)-c1c[nH]c(n1)C1(CCCC1)NCc1cc2ccccc2[nH]1 Show InChI InChI=1S/C24H26N4/c1-17-8-10-18(11-9-17)22-16-25-23(28-22)24(12-4-5-13-24)26-15-20-14-19-6-2-3-7-21(19)27-20/h2-3,6-11,14,16,26-27H,4-5,12-13,15H2,1H3,(H,25,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist activity at human SSTR3 expressed in CHO cells assessed as intracellular cAMP level after 45 mins by time-resolved fluorescence assay |
Bioorg Med Chem Lett 25: 3520-5 (2015)
Article DOI: 10.1016/j.bmcl.2015.06.087
BindingDB Entry DOI: 10.7270/Q29W0H9M |
More data for this
Ligand-Target Pair | |
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