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PubMed code 27836196

Compile data set for download or QSAR
Found 26 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231998
PNG
(CHEMBL4085835)
Show SMILES CCCCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC
Show InChI InChI=1S/C21H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)18(22)16-19(24-2)21(17)25-3/h16,22-23H,4-15H2,1-3H3
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n/an/a 28n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231991
PNG
(CHEMBL4093584)
Show SMILES CCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC
Show InChI InChI=1S/C19H32O4/c1-4-5-6-7-8-9-10-11-12-13-15-18(21)16(20)14-17(22-2)19(15)23-3/h14,20-21H,4-13H2,1-3H3
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n/an/a 30n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231998
PNG
(CHEMBL4085835)
Show SMILES CCCCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC
Show InChI InChI=1S/C21H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)18(22)16-19(24-2)21(17)25-3/h16,22-23H,4-15H2,1-3H3
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n/an/a 60n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231999
PNG
(CHEMBL4103758)
Show SMILES CCCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC
Show InChI InChI=1S/C20H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(23-2)20(16)24-3/h15,21-22H,4-14H2,1-3H3
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n/an/a 90n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231991
PNG
(CHEMBL4093584)
Show SMILES CCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC
Show InChI InChI=1S/C19H32O4/c1-4-5-6-7-8-9-10-11-12-13-15-18(21)16(20)14-17(22-2)19(15)23-3/h14,20-21H,4-13H2,1-3H3
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n/an/a 100n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232002
PNG
(CHEMBL4095644)
Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCCCCO)=C1OC |c:20,t:2|
Show InChI InChI=1S/C19H30O5/c1-23-17-14-16(21)18(22)15(19(17)24-2)12-10-8-6-4-3-5-7-9-11-13-20/h14,20H,3-13H2,1-2H3
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n/an/a 120n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231996
PNG
(CHEMBL4069339)
Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCO)=C1OC |c:17,t:2|
Show InChI InChI=1S/C16H24O5/c1-20-14-11-13(18)15(19)12(16(14)21-2)9-7-5-3-4-6-8-10-17/h11,17H,3-10H2,1-2H3
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n/an/a 150n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231993
PNG
(CHEMBL4088278)
Show SMILES COC1=CC(=O)C(OC)=C(CCCCCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C19H30O5/c1-23-17-14-16(21)19(24-2)15(18(17)22)12-10-8-6-4-3-5-7-9-11-13-20/h14,20H,3-13H2,1-2H3
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n/an/a 200n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231996
PNG
(CHEMBL4069339)
Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCO)=C1OC |c:17,t:2|
Show InChI InChI=1S/C16H24O5/c1-20-14-11-13(18)15(19)12(16(14)21-2)9-7-5-3-4-6-8-10-17/h11,17H,3-10H2,1-2H3
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n/an/a 220n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231999
PNG
(CHEMBL4103758)
Show SMILES CCCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC
Show InChI InChI=1S/C20H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(23-2)20(16)24-3/h15,21-22H,4-14H2,1-3H3
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n/an/a 240n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231997
PNG
(CHEMBL4089216)
Show SMILES CCCCCCCCCCCCCc1c(O)c(OC)cc(O)c1OC
Show InChI InChI=1S/C21H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)19(24-2)16-18(22)21(17)25-3/h16,22-23H,4-15H2,1-3H3
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n/an/a 260n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232003
PNG
(CHEMBL4061044)
Show SMILES CCCCCCCCCCCCCc1c(O)c(O)cc(OC)c1O
Show InChI InChI=1S/C20H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(24-2)20(16)23/h15,21-23H,3-14H2,1-2H3
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n/an/a 290n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231997
PNG
(CHEMBL4089216)
Show SMILES CCCCCCCCCCCCCc1c(O)c(OC)cc(O)c1OC
Show InChI InChI=1S/C21H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)19(24-2)16-18(22)21(17)25-3/h16,22-23H,4-15H2,1-3H3
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n/an/a 310n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232001
PNG
(CHEMBL4096012)
Show SMILES COC1=CC(=O)C(OC)=C(CCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C16H24O5/c1-20-14-11-13(18)16(21-2)12(15(14)19)9-7-5-3-4-6-8-10-17/h11,17H,3-10H2,1-2H3
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n/an/a 330n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231995
PNG
(CHEMBL4075247)
Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCCCO)=C1OC |c:19,t:2|
Show InChI InChI=1S/C18H28O5/c1-22-16-13-15(20)17(21)14(18(16)23-2)11-9-7-5-3-4-6-8-10-12-19/h13,19H,3-12H2,1-2H3
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n/an/a 360n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232000
PNG
(CHEMBL4065980)
Show SMILES COC1=CC(=O)C(OC)=C(C(CCCCCCCCCO)OC(C)=O)C1=O |t:2,8|
Show InChI InChI=1S/C20H30O7/c1-14(22)27-16(11-9-7-5-4-6-8-10-12-21)18-19(24)17(25-2)13-15(23)20(18)26-3/h13,16,21H,4-12H2,1-3H3
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n/an/a 490n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231994
PNG
(CHEMBL4077966)
Show SMILES COC1=CC(=O)C(OC)=C(CCCCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C18H28O5/c1-22-16-13-15(20)18(23-2)14(17(16)21)11-9-7-5-3-4-6-8-10-12-19/h13,19H,3-12H2,1-2H3
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n/an/a 550n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231992
PNG
(CHEMBL4067007)
Show SMILES COC1=CC(=O)C(OC)=C(C(O)CCCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C18H28O6/c1-23-15-12-14(21)18(24-2)16(17(15)22)13(20)10-8-6-4-3-5-7-9-11-19/h12-13,19-20H,3-11H2,1-2H3
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n/an/a 660n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231995
PNG
(CHEMBL4075247)
Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCCCO)=C1OC |c:19,t:2|
Show InChI InChI=1S/C18H28O5/c1-22-16-13-15(20)17(21)14(18(16)23-2)11-9-7-5-3-4-6-8-10-12-19/h13,19H,3-12H2,1-2H3
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n/an/a 1.08E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231992
PNG
(CHEMBL4067007)
Show SMILES COC1=CC(=O)C(OC)=C(C(O)CCCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C18H28O6/c1-23-15-12-14(21)18(24-2)16(17(15)22)13(20)10-8-6-4-3-5-7-9-11-19/h12-13,19-20H,3-11H2,1-2H3
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n/an/a 1.46E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231993
PNG
(CHEMBL4088278)
Show SMILES COC1=CC(=O)C(OC)=C(CCCCCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C19H30O5/c1-23-17-14-16(21)19(24-2)15(18(17)22)12-10-8-6-4-3-5-7-9-11-13-20/h14,20H,3-13H2,1-2H3
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n/an/a 1.51E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232003
PNG
(CHEMBL4061044)
Show SMILES CCCCCCCCCCCCCc1c(O)c(O)cc(OC)c1O
Show InChI InChI=1S/C20H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(24-2)20(16)23/h15,21-23H,3-14H2,1-2H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232000
PNG
(CHEMBL4065980)
Show SMILES COC1=CC(=O)C(OC)=C(C(CCCCCCCCCO)OC(C)=O)C1=O |t:2,8|
Show InChI InChI=1S/C20H30O7/c1-14(22)27-16(11-9-7-5-4-6-8-10-12-21)18-19(24)17(25-2)13-15(23)20(18)26-3/h13,16,21H,4-12H2,1-3H3
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n/an/a 1.62E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50231994
PNG
(CHEMBL4077966)
Show SMILES COC1=CC(=O)C(OC)=C(CCCCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C18H28O5/c1-22-16-13-15(20)18(23-2)14(17(16)21)11-9-7-5-3-4-6-8-10-12-19/h13,19H,3-12H2,1-2H3
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n/an/a 1.75E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232001
PNG
(CHEMBL4096012)
Show SMILES COC1=CC(=O)C(OC)=C(CCCCCCCCO)C1=O |t:2,8|
Show InChI InChI=1S/C16H24O5/c1-20-14-11-13(18)16(21-2)12(15(14)19)9-7-5-3-4-6-8-10-17/h11,17H,3-10H2,1-2H3
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n/an/a 1.84E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50232002
PNG
(CHEMBL4095644)
Show SMILES COC1=CC(=O)C(=O)C(CCCCCCCCCCCO)=C1OC |c:20,t:2|
Show InChI InChI=1S/C19H30O5/c1-23-17-14-16(21)18(22)15(19(17)24-2)12-10-8-6-4-3-5-7-9-11-13-20/h14,20H,3-13H2,1-2H3
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n/an/a 1.96E+3n/an/an/an/an/an/a



Second University of Naples

Curated by ChEMBL


Assay Description
Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...


Eur J Med Chem 127: 715-726 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.046
BindingDB Entry DOI: 10.7270/Q2DR2XQ8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%