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41 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28218840 38 Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis.EBI East China University of Science and Technology
28065501 38 Synthesis, docking, cytotoxicity, and LTAEBI Mansoura University
27651294 25 Thermodynamic properties of leukotriene AEBI Goethe-University Frankfurt
24125851 48 Novel acetamidothiazole derivatives: synthesis and in vitro anticancer evaluation.EBI University of Mansoura
23260350 49 Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.EBI Janssen Research and Development
23220644 50 Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase.EBI Peking University
23127888 56 Azabenzthiazole inhibitors of leukotriene A4 hydrolase.EBI Janssen Research and Development
22796349 34 Rapid and efficient synthesis of a novel series of substituted aminobenzosuberone derivatives as potent, selective, non-peptidic neutral aminopeptidase inhibitors.EBI Universit£
12139459 74 Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid.EBI Pfizer
10691697 133 Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase.EBI Searle Research and Development
 38 Kelatorphan and related analogs: potent and selective inhibitors of leukotriene A4 hydrolaseEBI TBA
 8 Probing the inhibition of leukotriene A4 hydrolase based on its aminopeptidase activityEBI TBA
22059882 206 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor.EBI Amira Pharmaceuticals
21542630 135 Discovery of dual target inhibitors against cyclooxygenases and leukotriene A4 hydrolyase.EBI Peking University
21377770 26 Pharmacophore-based virtual screening and Bayesian model for the identification of potential human leukotriene A4 hydrolase inhibitors.EBI Gyeongsang National University (Gnu)
21292493 23 Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13.EBI Merck Sharpe and Dohme
20371179 37 Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds.EBI Decode Chemistry
19950900 18 Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.EBI Decode Chemistry
19618939 36 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.EBI Decode Biostructures
8904845 3 Isolation and structure of leukotriene-A4 hydrolase inhibitor: 8(S)-amino-2(R)-methyl-7-oxononanoic acid produced by Streptomyces diastaticus.EBI Searle Research and Development
19090779 12 Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching.EBI Peking University
18952425 8 Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives.EBI Peking University
18674901 32 Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.EBI Santen Pharmaceutical
18590959 61 Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.EBI Berlex Biosciences
18586492 81 Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.EBI Berlex Biosciences
12643929 18 Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase.EBI Pfizer
12419366 27 Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase.EBI Pharmacia
32551007 19 Computer-Aided Fragment Growing Strategies to Design Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase.EBI Goethe-University
31751136 6 Effect of Modifier Structure on the Activation of Leukotriene AEBI George Mason University
32184960 34 Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTAEBI Goethe University Frankfurt
30846252 23 Recent developments in the synthesis and applications of phosphinic peptide analogs.EBI Wroclaw University of Technology
8423594 39 Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.EBI Scripps Research Institute
29630364 63 Design of Aminopeptidase N Inhibitors as Anti-cancer Agents.EBI Jadavpur University
10926521 15 Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design.BDB Max-Planck-Institut Fuer Biochemie