Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM254888 (US9493472, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254889 (US9493472, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254905 (US9493472, 27) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254904 (US9493472, 26) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254886 (US9493472, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254896 (US9493472, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254895 (US9493472, 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254911 (US9493472, 33) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254894 (US9493472, 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254907 (US9493472, 29 | US9493472, 30 | US9493472, 31) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254910 (US9493472, 32) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254892 (US9493472, 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.720 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254897 (US9493472, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254882 (US9493472, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254907 (US9493472, 29 | US9493472, 30 | US9493472, 31) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254890 (US9493472, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254898 (US9493472, 20) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254899 (US9493472, 21) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254900 (US9493472, 22) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254881 (US9493472, 4 | US9493472, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254901 (US9493472, 23) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254891 (US9493472, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091927 (1-(2,6-Dichloro-phenyl)-1-(4'-fluoro-6-hydroxymeth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli. | Bioorg Med Chem Lett 10: 2047-50 (2000) BindingDB Entry DOI: 10.7270/Q2FB526H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254906 (US9493472, 28) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254880 (US9493472, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254878 (US9493472, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254903 (US9493472, 25) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254902 (US9493472, 24) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254884 (US9493472, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254907 (US9493472, 29 | US9493472, 30 | US9493472, 31) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50139601 (1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory activity against human Raf-1 kinase | Bioorg Med Chem Lett 14: 783-6 (2004) BindingDB Entry DOI: 10.7270/Q2TM79JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase [305-648] (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 8.2 | 32 |
Bayer Pharmaceuticals Corporation | Assay Description The biochemical activity of compound was determined by incubation with Raf kinases and substrate MEK-1 in the presence of 1-10 uM ATP/ [gamma-32P] AT... | Cancer Res 64: 7099-109 (2004) Article DOI: 10.1158/0008-5472.CAN-04-1443 BindingDB Entry DOI: 10.7270/Q2H70D2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254881 (US9493472, 4 | US9493472, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091931 (1-[5-tert-Butyl-2-(3-nitro-phenyl)-2H-pyrazol-3-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254885 (US9493472, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory activity against human Raf-1 kinase | Bioorg Med Chem Lett 14: 783-6 (2004) BindingDB Entry DOI: 10.7270/Q2TM79JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091935 (1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Mus musculus) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Bayer Pharmaceuticals Corporation | Assay Description Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono... | Cancer Res 64: 7099-109 (2004) Article DOI: 10.1158/0008-5472.CAN-04-1443 BindingDB Entry DOI: 10.7270/Q2H70D2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 3 (Mus musculus (mouse)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Bayer Pharmaceuticals Corporation | Assay Description Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono... | Cancer Res 64: 7099-109 (2004) Article DOI: 10.1158/0008-5472.CAN-04-1443 BindingDB Entry DOI: 10.7270/Q2H70D2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli. | Bioorg Med Chem Lett 10: 2047-50 (2000) BindingDB Entry DOI: 10.7270/Q2FB526H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254913 (US9493472, 34) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [409-765] (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 8.2 | 32 |
Bayer Pharmaceuticals Corporation | Assay Description The biochemical activity of compound was determined by incubation with Raf kinases and substrate MEK-1 in the presence of 1-10 uM ATP/ [gamma-32P] AT... | Cancer Res 64: 7099-109 (2004) Article DOI: 10.1158/0008-5472.CAN-04-1443 BindingDB Entry DOI: 10.7270/Q2H70D2J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50139614 (4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory activity against human Raf-1 kinase | Bioorg Med Chem Lett 14: 783-6 (2004) BindingDB Entry DOI: 10.7270/Q2TM79JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50139618 (4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory activity against human Raf-1 kinase | Bioorg Med Chem Lett 14: 783-6 (2004) BindingDB Entry DOI: 10.7270/Q2TM79JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091954 (1-[2-(4-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091951 (1-(5-tert-Butyl-2-phenyl-2H-pyrazol-3-yl)-3-(2,3-d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM254879 (US9493472, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s... | US Patent US9493472 (2016) BindingDB Entry DOI: 10.7270/Q2B56HPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091933 (1-[5-tert-Butyl-2-(4-methanesulfonyl-phenyl)-2H-py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50091939 (1-[5-tert-Butyl-2-(3-fluoro-phenyl)-2H-pyrazol-3-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2 | Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS | |||||||||||
More data for this Ligand-Target Pair |
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