Compile Data Set for Download or QSAR

Found 690 hits with Last Name = 'cooper' and Initial = 'cb'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50341977 (2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-hydroxybenzoic a...) Show SMILES Cc1ccc(C)n1-c1ccc(O)cc1C(O)=O |(5.57,-.15,;4.1,-.62,;3.62,-2.09,;2.08,-2.09,;1.61,-.62,;.14,-.15,;2.86,.28,;2.85,1.82,;1.51,2.59,;1.51,4.14,;2.84,4.91,;2.84,6.45,;4.18,4.14,;4.18,2.59,;5.66,2.2,;6.75,3.29,;6.06,.71,)| Show InChI InChI=1S/C13H13NO3/c1-8-3-4-9(2)14(8)12-6-5-10(15)7-11(12)13(16)17/h3-7,15H,1-2H3,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Global Alliance for TB Drug Development (TB Alliance) Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PtpA				J Med Chem 56: 7755-60 (2013) Article DOI: 10.1021/jm400381v BindingDB Entry DOI: 10.7270/Q2000514
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32522 (pyridine amide, 30) Show SMILES Cc1ccc(cc1F)-c1cccc(n1)C(=O)N1CCCC(C)(C)C1 Show InChI InChI=1S/C20H23FN2O/c1-14-8-9-15(12-16(14)21)17-6-4-7-18(22-17)19(24)23-11-5-10-20(2,3)13-23/h4,6-9,12H,5,10-11,13H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (crystal)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32520 (pyridine amide, 28) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(2)11-4-12-22(13-19)18(23)17-6-3-5-16(21-17)14-7-9-15(20)10-8-14/h3,5-10H,4,11-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32521 (pyridine amide, 29) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(n1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N2O2/c1-19(2)11-4-12-25(13-19)18(26)17-6-3-5-16(24-17)14-7-9-15(10-8-14)27-20(21,22)23/h3,5-10H,4,11-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32527 (pyridine amide, 35) Show SMILES [H][C@]12C[C@](C)(CN1C(=O)c1cncc(COc3c(Cl)cccc3Cl)c1)CC(C)(C)C2 |r| Show InChI InChI=1S/C23H26Cl2N2O2/c1-22(2)8-17-9-23(3,13-22)14-27(17)21(28)16-7-15(10-26-11-16)12-29-20-18(24)5-4-6-19(20)25/h4-7,10-11,17H,8-9,12-14H2,1-3H3/t17-,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32526 (pyridine amide, 34) Show SMILES Clc1cccc(Cl)c1OCc1cncc(c1)C(=O)N1CCCCC1c1cccnc1 Show InChI InChI=1S/C23H21Cl2N3O2/c24-19-6-3-7-20(25)22(19)30-15-16-11-18(14-27-12-16)23(29)28-10-2-1-8-21(28)17-5-4-9-26-13-17/h3-7,9,11-14,21H,1-2,8,10,15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32523 (pyridine amide, 31) Show SMILES [O-][N+](=O)c1ccccc1-c1cccc(n1)C(=O)N1CCCC2CCCCC12 Show InChI InChI=1S/C21H23N3O3/c25-21(23-14-6-8-15-7-1-3-12-19(15)23)18-11-5-10-17(22-18)16-9-2-4-13-20(16)24(26)27/h2,4-5,9-11,13,15,19H,1,3,6-8,12,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32508 (pyridine amide, 23) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCCCCC1 Show InChI InChI=1S/C21H24Cl2N2O3S/c22-18-8-7-9-19(23)20(18)29(27,28)15-16-12-17(14-24-13-16)21(26)25-10-5-3-1-2-4-6-11-25/h7-9,12-14H,1-6,10-11,15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32519 (pyridine amide, 27) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(n1)-c1ccccc1Cl Show InChI InChI=1S/C19H21ClN2O/c1-19(2)11-6-12-22(13-19)18(23)17-10-5-9-16(21-17)14-7-3-4-8-15(14)20/h3-5,7-10H,6,11-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES O[C@H](CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F Show InChI InChI=1S/C24H20F7NO3/c25-22(26)24(30,31)35-20-11-4-6-16(12-20)14-32(15-21(33)23(27,28)29)17-7-5-10-19(13-17)34-18-8-2-1-3-9-18/h1-13,21-22,33H,14-15H2/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32524 (pyridine amide, 32) Show SMILES FC(F)(F)c1ccc(cc1)-c1cccc(n1)C(=O)N1CCCC2CCCCC12 Show InChI InChI=1S/C22H23F3N2O/c23-22(24,25)17-12-10-15(11-13-17)18-7-3-8-19(26-18)21(28)27-14-4-6-16-5-1-2-9-20(16)27/h3,7-8,10-13,16,20H,1-2,4-6,9,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32529 (pyridine amide, 37) Show SMILES Clc1cccc(Cl)c1OCc1cccc(n1)C(=O)N1CCCC2CCCCC12 Show InChI InChI=1S/C22H24Cl2N2O2/c23-17-9-4-10-18(24)21(17)28-14-16-8-3-11-19(25-16)22(27)26-13-5-7-15-6-1-2-12-20(15)26/h3-4,8-11,15,20H,1-2,5-7,12-14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32525 (pyridine amide, 33) Show SMILES O=C(N1CCCC2CCCCC12)c1cccc(n1)-c1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H28N2O/c30-27(29-19-9-13-21-12-4-7-18-26(21)29)25-17-8-16-24(28-25)23-15-6-5-14-22(23)20-10-2-1-3-11-20/h1-3,5-6,8,10-11,14-17,21,26H,4,7,9,12-13,18-19H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155213 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-8-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2ccncc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)12-4-1-5-12)20-14-6-2-3-11-7-8-18-9-13(11)14/h2-3,6-10,12H,1,4-5H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32528 (pyridine amide, 36) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(COc2c(Cl)cc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H21Cl3N2O2/c1-20(2)7-4-8-25(12-20)19(26)17-6-3-5-14(24-17)11-27-18-15(22)9-13(21)10-16(18)23/h3,5-6,9-10H,4,7-8,11-12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50392512 (CHEMBL2152165) Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H25ClF5N3O2/c28-19-10-11-23(34-16-19)26(15-17-6-2-1-3-7-17,36-25(37)35-21-8-4-5-9-21)18-12-20(29)14-22(13-18)38-27(32,33)24(30)31/h1-3,6-7,10-14,16,21,24H,4-5,8-9,15H2,(H2,35,36,37)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assay				J Med Chem 55: 6162-75 (2012) Article DOI: 10.1021/jm300611v BindingDB Entry DOI: 10.7270/Q2KH0PF5
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM50302339 (CHEMBL567281 | N-(1-(4'-(4-phenoxyphenoxy)biphenyl...) Show SMILES CC(NC(C)=O)c1ccc(cc1)-c1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C28H25NO3/c1-20(29-21(2)30)22-8-10-23(11-9-22)24-12-14-26(15-13-24)32-28-18-16-27(17-19-28)31-25-6-4-3-5-7-25/h3-20H,1-2H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155231 (2-(1H-Benzoimidazol-5-yl)-N-(5-cyclobutyl-thiazol-...) Show SMILES O=C(Cc1ccc2nc[nH]c2c1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C16H16N4OS/c21-15(7-10-4-5-12-13(6-10)19-9-18-12)20-16-17-8-14(22-16)11-2-1-3-11/h4-6,8-9,11H,1-3,7H2,(H,18,19)(H,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32512 (pyridine amide, 6) Show SMILES CC1CCN(CC1)C(=O)c1cccc(CSc2c(Cl)cccc2Cl)n1 Show InChI InChI=1S/C19H20Cl2N2OS/c1-13-8-10-23(11-9-13)19(24)17-7-2-4-14(22-17)12-25-18-15(20)5-3-6-16(18)21/h2-7,13H,8-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM50302369 ((S)-N-(1-(4-(6-(4-propoxyphenoxy)pyridin-3-yl)phen...) Show SMILES CCCOc1ccc(Oc2ccc(cn2)-c2ccc(cc2)[C@H](C)NC(C)=O)cc1 |r| Show InChI InChI=1S/C24H26N2O3/c1-4-15-28-22-10-12-23(13-11-22)29-24-14-9-21(16-25-24)20-7-5-19(6-8-20)17(2)26-18(3)27/h5-14,16-17H,4,15H2,1-3H3,(H,26,27)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155209 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-5-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2cnccc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-3-1-4-11)20-14-6-2-5-12-9-18-8-7-13(12)14/h2,5-11H,1,3-4H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155236 (CHEMBL363954 | N-(5-Cyclobutyl-thiazol-2-yl)-2-qui...) Show SMILES O=C(Cc1ccc2ncccc2c1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C18H17N3OS/c22-17(21-18-20-11-16(23-18)13-3-1-4-13)10-12-6-7-15-14(9-12)5-2-8-19-15/h2,5-9,11,13H,1,3-4,10H2,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376718 (CHEMBL261502) Show SMILES Cc1c(Cl)ccc(OCC(=O)Nc2ccc(cc2)-c2nc3cc(ccc3o2)C#N)c1C Show InChI InChI=1S/C24H18ClN3O3/c1-14-15(2)21(10-8-19(14)25)30-13-23(29)27-18-6-4-17(5-7-18)24-28-20-11-16(12-26)3-9-22(20)31-24/h3-11H,13H2,1-2H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376712 (CHEMBL259502) Show SMILES Cc1cc(Br)ccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N Show InChI InChI=1S/C23H16BrN3O3/c1-14-10-17(24)5-9-20(14)29-13-22(28)26-18-6-3-16(4-7-18)23-27-19-11-15(12-25)2-8-21(19)30-23/h2-11H,13H2,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32507 (pyridine amide, 22) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCCCC1 Show InChI InChI=1S/C20H22Cl2N2O3S/c21-17-7-6-8-18(22)19(17)28(26,27)14-15-11-16(13-23-12-15)20(25)24-9-4-2-1-3-5-10-24/h6-8,11-13H,1-5,9-10,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155235 (CHEMBL186470 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-...) Show SMILES Cc1nc2ccc(CC(=O)Nc3ncc(s3)C3CCC3)cc2s1 Show InChI InChI=1S/C17H17N3OS2/c1-10-19-13-6-5-11(7-14(13)22-10)8-16(21)20-17-18-9-15(23-17)12-3-2-4-12/h5-7,9,12H,2-4,8H2,1H3,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM50302368 (CHEMBL567291 | N-(1-(4'-(3-propoxyphenoxy)biphenyl...) Show SMILES CCCOc1cccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)c1 Show InChI InChI=1S/C25H27NO3/c1-4-16-28-24-6-5-7-25(17-24)29-23-14-12-22(13-15-23)21-10-8-20(9-11-21)18(2)26-19(3)27/h5-15,17-18H,4,16H2,1-3H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155230 (CHEMBL187903 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,...) Show SMILES Cc1cc2ncn(CC(=O)Nc3ncc(s3)C3CCC3)c2cc1C Show InChI InChI=1S/C18H20N4OS/c1-11-6-14-15(7-12(11)2)22(10-20-14)9-17(23)21-18-19-8-16(24-18)13-4-3-5-13/h6-8,10,13H,3-5,9H2,1-2H3,(H,19,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155237 (CHEMBL184404 | N-(5-Cyclobutyl-thiazol-2-yl)-2-iso...) Show SMILES O=C(Cc1cccc2cnccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C18H17N3OS/c22-17(21-18-20-11-16(23-18)12-3-1-4-12)9-13-5-2-6-14-10-19-8-7-15(13)14/h2,5-8,10-12H,1,3-4,9H2,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (Homo sapiens (Human))	BDBM50302368 (CHEMBL567291 | N-(1-(4'-(3-propoxyphenoxy)biphenyl...) Show SMILES CCCOc1cccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)c1 Show InChI InChI=1S/C25H27NO3/c1-4-16-28-24-6-5-7-25(17-24)29-23-14-12-22(13-15-23)21-10-8-20(9-11-21)18(2)26-19(3)27/h5-15,17-18H,4,16H2,1-3H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155207 (1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-5-yl-urea...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2ncccc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-4-1-5-11)20-14-8-2-7-13-12(14)6-3-9-18-13/h2-3,6-11H,1,4-5H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (Homo sapiens (Human))	BDBM50302339 (CHEMBL567281 | N-(1-(4'-(4-phenoxyphenoxy)biphenyl...) Show SMILES CC(NC(C)=O)c1ccc(cc1)-c1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C28H25NO3/c1-20(29-21(2)30)22-8-10-23(11-9-22)24-12-14-26(15-13-24)32-28-18-16-27(17-19-28)31-25-6-4-3-5-7-25/h3-20H,1-2H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM50302337 (CHEMBL567935 | N-(1-(4'-(4-propoxyphenoxy)biphenyl...) Show SMILES CCCOc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-4-17-28-23-13-15-25(16-14-23)29-24-11-9-22(10-12-24)21-7-5-20(6-8-21)18(2)26-19(3)27/h5-16,18H,4,17H2,1-3H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50394941 (CHEMBL2165719) Show SMILES COc1ccc(cn1)[C@@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1cc(F)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C27H27F4N3O2/c1-36-24-12-11-19(17-32-24)26(16-18-7-3-2-4-8-18,34-25(35)33-23-9-5-6-10-23)20-13-21(27(29,30)31)15-22(28)14-20/h2-4,7-8,11-15,17,23H,5-6,9-10,16H2,1H3,(H2,33,34,35)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assay				J Med Chem 55: 6162-75 (2012) Article DOI: 10.1021/jm300611v BindingDB Entry DOI: 10.7270/Q2KH0PF5
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376713 (CHEMBL259710) Show SMILES Clc1ccc(OCC(=O)Nc2ccc(cc2)-c2nc3cc(ccc3o2)C#N)c2CCCc12 Show InChI InChI=1S/C25H18ClN3O3/c26-20-9-11-22(19-3-1-2-18(19)20)31-14-24(30)28-17-7-5-16(6-8-17)25-29-21-12-15(13-27)4-10-23(21)32-25/h4-12H,1-3,14H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155235 (CHEMBL186470 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-...) Show SMILES Cc1nc2ccc(CC(=O)Nc3ncc(s3)C3CCC3)cc2s1 Show InChI InChI=1S/C17H17N3OS2/c1-10-19-13-6-5-11(7-14(13)22-10)8-16(21)20-17-18-9-15(23-17)12-3-2-4-12/h5-7,9,12H,2-4,8H2,1H3,(H,18,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50394932 (CHEMBL2165691) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1F)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H23ClF5N3O/c27-19-9-10-23(33-15-19)25(14-16-5-1-4-8-22(16)29,35-24(36)34-21-6-2-3-7-21)17-11-18(26(30,31)32)13-20(28)12-17/h1,4-5,8-13,15,21H,2-3,6-7,14H2,(H2,34,35,36)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assay				J Med Chem 55: 6162-75 (2012) Article DOI: 10.1021/jm300611v BindingDB Entry DOI: 10.7270/Q2KH0PF5
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (Homo sapiens (Human))	BDBM50302355 (CHEMBL565818 | N-(1-(4'-(4-isopropoxyphenoxy)-2'-m...) Show SMILES CC(C)Oc1ccc(Oc2ccc(c(C)c2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C26H29NO3/c1-17(2)29-23-10-12-24(13-11-23)30-25-14-15-26(18(3)16-25)22-8-6-21(7-9-22)19(4)27-20(5)28/h6-17,19H,1-5H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM50302366 (CHEMBL585885 | N-(1-(4'-(3-phenoxyphenoxy)biphenyl...) Show SMILES CC(NC(C)=O)c1ccc(cc1)-c1ccc(Oc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C28H25NO3/c1-20(29-21(2)30)22-11-13-23(14-12-22)24-15-17-26(18-16-24)32-28-10-6-9-27(19-28)31-25-7-4-3-5-8-25/h3-20H,1-2H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155214 (CHEMBL186240 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H...) Show SMILES O=C(Cc1c[nH]c2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(8-12-9-18-14-7-2-1-6-13(12)14)20-17-19-10-15(22-17)11-4-3-5-11/h1-2,6-7,9-11,18H,3-5,8H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32518 (pyridine amide, 9) Show SMILES CC1CCN(CC1)C(=O)c1cccc(n1)-c1ccccc1Cl Show InChI InChI=1S/C18H19ClN2O/c1-13-9-11-21(12-10-13)18(22)17-8-4-7-16(20-17)14-5-2-3-6-15(14)19/h2-8,13H,9-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
Acetyl-CoA carboxylase 1 (Homo sapiens (Human))	BDBM50302337 (CHEMBL567935 | N-(1-(4'-(4-propoxyphenoxy)biphenyl...) Show SMILES CCCOc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-4-17-28-23-13-15-25(16-14-23)29-24-11-9-22(10-12-24)21-7-5-20(6-8-21)18(2)26-19(3)27/h5-16,18H,4,17H2,1-3H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (Homo sapiens (Human))	BDBM50302338 (CHEMBL567936 | N-(1-(4'-(4-isopropoxyphenoxy)biphe...) Show SMILES CC(C)Oc1ccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C25H27NO3/c1-17(2)28-23-13-15-25(16-14-23)29-24-11-9-22(10-12-24)21-7-5-20(6-8-21)18(3)26-19(4)27/h5-18H,1-4H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376719 (CHEMBL258795) Show SMILES FC(F)(F)c1cc(OCC(=O)Nc2ccc(cc2)-c2nc3cc(ccc3o2)C#N)ccc1Cl Show InChI InChI=1S/C23H13ClF3N3O3/c24-18-7-6-16(10-17(18)23(25,26)27)32-12-21(31)29-15-4-2-14(3-5-15)22-30-19-9-13(11-28)1-8-20(19)33-22/h1-10H,12H2,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (Homo sapiens (Human))	BDBM50302351 (CHEMBL585578 | N-(1-(4-6-(4-propoxyphenoxy)pyridin...) Show SMILES CCCOc1ccc(Oc2ccc(cn2)-c2ccc(cc2)C(C)NC(C)=O)cc1 Show InChI InChI=1S/C24H26N2O3/c1-4-15-28-22-10-12-23(13-11-22)29-24-14-9-21(16-25-24)20-7-5-19(6-8-20)17(2)26-18(3)27/h5-14,16-17H,4,15H2,1-3H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376711 (CHEMBL259503) Show SMILES COC(=O)c1c(Cl)ccc(OCC(=O)Nc2ccc(cc2)-c2nc3cc(ccc3o2)C#N)c1C Show InChI InChI=1S/C25H18ClN3O5/c1-14-20(10-8-18(26)23(14)25(31)32-2)33-13-22(30)28-17-6-4-16(5-7-17)24-29-19-11-15(12-27)3-9-21(19)34-24/h3-11H,13H2,1-2H3,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50392499 (CHEMBL2152152) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H24ClF4N3O/c27-20-10-11-23(32-16-20)25(15-17-6-2-1-3-7-17,34-24(35)33-22-8-4-5-9-22)18-12-19(26(29,30)31)14-21(28)13-18/h1-3,6-7,10-14,16,22H,4-5,8-9,15H2,(H2,33,34,35)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assay				J Med Chem 55: 6162-75 (2012) Article DOI: 10.1021/jm300611v BindingDB Entry DOI: 10.7270/Q2KH0PF5
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32506 (pyridine amide, 21) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCCC1 Show InChI InChI=1S/C19H20Cl2N2O3S/c20-16-6-5-7-17(21)18(16)27(25,26)13-14-10-15(12-22-11-14)19(24)23-8-3-1-2-4-9-23/h5-7,10-12H,1-4,8-9,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32500 (pyridine amide, 15) Show SMILES CC1CCN(CC1)C(=O)c1cncc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-5-7-23(8-6-13)19(24)15-9-14(10-22-11-15)12-27(25,26)18-16(20)3-2-4-17(18)21/h2-4,9-11,13H,5-8,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376693 (CHEMBL409318) Show SMILES Cc1cc(C)c2oc(nc2c1)-c1ccc(NC(=O)COc2ccc(F)cc2C)cc1 Show InChI InChI=1S/C24H21FN2O3/c1-14-10-16(3)23-20(11-14)27-24(30-23)17-4-7-19(8-5-17)26-22(28)13-29-21-9-6-18(25)12-15(21)2/h4-12H,13H2,1-3H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair

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