Compile Data Set for Download or QSAR

Found 76 hits with Last Name = 'nuth' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208055 (3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c(CC(N)=O)[nH]c2c1 Show InChI InChI=1S/C17H14Cl2N2OS/c1-9-2-3-13-14(4-9)21-15(8-16(20)22)17(13)23-12-6-10(18)5-11(19)7-12/h2-7,21H,8H2,1H3,(H2,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208056 (2-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(N)=O Show InChI InChI=1S/C16H12Cl2N2OS/c1-8-2-3-12-13(4-8)20-14(16(19)21)15(12)22-11-6-9(17)5-10(18)7-11/h2-7,20H,1H3,(H2,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208057 ( 4-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c(CCCC(N)=O)[nH]c2c1 Show InChI InChI=1S/C19H18Cl2N2OS/c1-11-5-6-15-17(7-11)23-16(3-2-4-18(22)24)19(15)25-14-9-12(20)8-13(21)10-14/h5-10,23H,2-4H2,1H3,(H2,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208058 (3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c(CCC(N)=O)[nH]c2c1 Show InChI InChI=1S/C18H16Cl2N2OS/c1-10-2-3-14-16(6-10)22-15(4-5-17(21)23)18(14)24-13-8-11(19)7-12(20)9-13/h2-3,6-9,22H,4-5H2,1H3,(H2,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM33154 (4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmet...) Show SMILES Oc1ccc(NCc2ccccc2OCc2ccccc2)cc1 Show InChI InChI=1S/C20H19NO2/c22-19-12-10-18(11-13-19)21-14-17-8-4-5-9-20(17)23-15-16-6-2-1-3-7-16/h1-13,21-22H,14-15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208048 ( 3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indole-2...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-2-3-12-13(4-8)19-14(16(20)21)15(12)22-11-6-9(17)5-10(18)7-11/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208049 (3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...) Show SMILES CCc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-2-9-3-4-13-14(5-9)20-15(17(21)22)16(13)23-12-7-10(18)6-11(19)8-12/h3-8,20H,2H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208051 (6-Methyl-3-(phenylthio)-1H-indole-2-carboxylate |...) Show SMILES COC(=O)c1[nH]c2cc(C)ccc2c1Sc1ccccc1 Show InChI InChI=1S/C17H15NO2S/c1-11-8-9-13-14(10-11)18-15(17(19)20-2)16(13)21-12-6-4-3-5-7-12/h3-10,18H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208054 (4-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...) Show SMILES Cc1cccc2[nH]c(C(O)=O)c(Sc3cc(Cl)c(Cl)cc3Cl)c12 Show InChI InChI=1S/C16H10Cl3NO2S/c1-7-3-2-4-11-13(7)15(14(20-11)16(21)22)23-12-6-9(18)8(17)5-10(12)19/h2-6,20H,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208038 (Methyl 3-((4-chlorophenyl)thio)-6-methyl-1H-indole...) Show SMILES COC(=O)c1[nH]c2cc(C)ccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-3-8-13-14(9-10)19-15(17(20)21-2)16(13)22-12-6-4-11(18)5-7-12/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208053 (7-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...) Show SMILES Cc1cccc2c(Sc3cc(Cl)c(Cl)cc3Cl)c([nH]c12)C(O)=O Show InChI InChI=1S/C16H10Cl3NO2S/c1-7-3-2-4-8-13(7)20-14(16(21)22)15(8)23-12-6-10(18)9(17)5-11(12)19/h2-6,20H,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208040 (Methyl 3-((4-chlorophenyl)thio)-4-methyl-1H-indole...) Show SMILES COC(=O)c1[nH]c2cccc(C)c2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-4-3-5-13-14(10)16(15(19-13)17(20)21-2)22-12-8-6-11(18)7-9-12/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208039 (Methyl 3-((4-chlorophenyl)thio)-7-methyl-1H-indole...) Show SMILES COC(=O)c1[nH]c2c(C)cccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-4-3-5-13-14(10)19-15(17(20)21-2)16(13)22-12-8-6-11(18)7-9-12/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208052 (6-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...) Show SMILES Cc1ccc2c(Sc3cc(Cl)c(Cl)cc3Cl)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H10Cl3NO2S/c1-7-2-3-8-12(4-7)20-14(16(21)22)15(8)23-13-6-10(18)9(17)5-11(13)19/h2-6,20H,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208043 (6-Methyl-3-((4-(trifluoromethyl)phenyl)thio)-1H-in...) Show SMILES Cc1ccc2c(Sc3ccc(cc3)C(F)(F)F)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H12F3NO2S/c1-9-2-7-12-13(8-9)21-14(16(22)23)15(12)24-11-5-3-10(4-6-11)17(18,19)20/h2-8,21H,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208045 (3-((3,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...) Show SMILES Cc1ccc2c(Sc3ccc(Cl)c(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-2-4-10-13(6-8)19-14(16(20)21)15(10)22-9-3-5-11(17)12(18)7-9/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343395 (10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15...) Show SMILES OCCN=C1CC(NC2CCCCC2)c2c(O)c3ccccc3c3onc1c23 |w:3.2| Show InChI InChI=1S/C22H25N3O3/c26-11-10-23-17-12-16(24-13-6-2-1-3-7-13)18-19-20(17)25-28-22(19)15-9-5-4-8-14(15)21(18)27/h4-5,8-9,13,16,24,26-27H,1-3,6-7,10-12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208046 (3-((3,4-Dichlorophenyl)thio)-7-methyl-1H-indole-2-...) Show SMILES Cc1cccc2c(Sc3ccc(Cl)c(Cl)c3)c([nH]c12)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-3-2-4-10-13(8)19-14(16(20)21)15(10)22-9-5-6-11(17)12(18)7-9/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208032 (3-((4-Chlorophenyl)thio)-6-ethyl-1H-indole-2-carbo...) Show SMILES CCc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H14ClNO2S/c1-2-10-3-8-13-14(9-10)19-15(17(20)21)16(13)22-12-6-4-11(18)5-7-12/h3-9,19H,2H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208044 (3-((2,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...) Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3Cl)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-2-4-10-12(6-8)19-14(16(20)21)15(10)22-13-5-3-9(17)7-11(13)18/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM80984 (4-chloranyl-2-(5-chloranyl-2-oxidanyl-phenyl)sulfa...) Show SMILES Oc1ccc(Cl)cc1Sc1cc(Cl)ccc1O Show InChI InChI=1S/C12H8Cl2O2S/c13-7-1-3-9(15)11(5-7)17-12-6-8(14)2-4-10(12)16/h1-6,15-16H	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208037 (Methyl 3-((4-chlorophenyl)thio)-1-ethyl-5-methyl-1...) Show SMILES CCn1c(C(=O)OC)c(Sc2ccc(Cl)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C19H18ClNO2S/c1-4-21-16-10-5-12(2)11-15(16)18(17(21)19(22)23-3)24-14-8-6-13(20)7-9-14/h5-11H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208031 (6-Fluoro-3-((4-chlorophenyl)thio)-1H-indole-2-carb...) Show SMILES OC(=O)c1[nH]c2cc(F)ccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C15H9ClFNO2S/c16-8-1-4-10(5-2-8)21-14-11-6-3-9(17)7-12(11)18-13(14)15(19)20/h1-7,18H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208047 (3-((3,4-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...) Show SMILES CCc1ccc2c(Sc3ccc(Cl)c(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-2-9-3-5-11-14(7-9)20-15(17(21)22)16(11)23-10-4-6-12(18)13(19)8-10/h3-8,20H,2H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208050 (3-((3,5-Dichlorophenyl)thio)-1H-indole-2-carboxyli...) Show SMILES OC(=O)c1[nH]c2ccccc2c1Sc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C15H9Cl2NO2S/c16-8-5-9(17)7-10(6-8)21-14-11-3-1-2-4-12(11)18-13(14)15(19)20/h1-7,18H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208027 (3-((4-Chlorophenyl)thio)-5-methyl-1H-indole-2-carb...) Show SMILES Cc1ccc2[nH]c(C(O)=O)c(Sc3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C16H12ClNO2S/c1-9-2-7-13-12(8-9)15(14(18-13)16(19)20)21-11-5-3-10(17)4-6-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208029 (6-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carb...) Show SMILES OC(=O)c1[nH]c2cc(Cl)ccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C15H9Cl2NO2S/c16-8-1-4-10(5-2-8)21-14-11-6-3-9(17)7-12(11)18-13(14)15(19)20/h1-7,18H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208033 ( 3-((4-chlorophenyl)thio)-4,7-dimethyl-1H-indole-2...) Show SMILES Cc1ccc(C)c2c(Sc3ccc(Cl)cc3)c([nH]c12)C(O)=O Show InChI InChI=1S/C17H14ClNO2S/c1-9-3-4-10(2)14-13(9)16(15(19-14)17(20)21)22-12-7-5-11(18)6-8-12/h3-8,19H,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208030 ( 6-Bromo-3-((4-chlorophenyl)thio)-1H-indole-2-carb...) Show SMILES OC(=O)c1[nH]c2cc(Br)ccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C15H9BrClNO2S/c16-8-1-6-11-12(7-8)18-13(15(19)20)14(11)21-10-4-2-9(17)3-5-10/h1-7,18H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208041 (3-((3-Chlorophenyl)thio)-6-methyl-1H-indole-2-carb...) Show SMILES Cc1ccc2c(Sc3cccc(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H12ClNO2S/c1-9-5-6-12-13(7-9)18-14(16(19)20)15(12)21-11-4-2-3-10(17)8-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208042 (3-((3-Fluorophenyl)thio)-6-methyl-1H-indole-2-carb...) Show SMILES Cc1ccc2c(Sc3cccc(F)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H12FNO2S/c1-9-5-6-12-13(7-9)18-14(16(19)20)15(12)21-11-4-2-3-10(17)8-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208028 (3-((4-Chlorophenyl)thio)-7-methyl-1H-indole-2-carb...) Show SMILES Cc1cccc2c(Sc3ccc(Cl)cc3)c([nH]c12)C(O)=O Show InChI InChI=1S/C16H12ClNO2S/c1-9-3-2-4-12-13(9)18-14(16(19)20)15(12)21-11-7-5-10(17)6-8-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM196157 (US9211296, Table 6, 11 | US9233921, 1) Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H12ClNO2S/c1-9-2-7-12-13(8-9)18-14(16(19)20)15(12)21-11-5-3-10(17)4-6-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208035 (3-((4-Chlorophenyl)thio)-1-ethyl-5-methyl-1H-indol...) Show SMILES CCn1c(C(O)=O)c(Sc2ccc(Cl)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C18H16ClNO2S/c1-3-20-15-9-4-11(2)10-14(15)17(16(20)18(21)22)23-13-7-5-12(19)6-8-13/h4-10H,3H2,1-2H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208026 (3-((4-Chlorophenyl)thio)-4-methyl-1H-indole-2-carb...) Show SMILES Cc1cccc2[nH]c(C(O)=O)c(Sc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C16H12ClNO2S/c1-9-3-2-4-12-13(9)15(14(18-12)16(19)20)21-11-7-5-10(17)6-8-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343412 (4-[5-(4-bromophenyl)-4-phenyl-1H-imidazol-2-yl]-2,...) Show SMILES COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccc(Br)cc1)-c1ccccc1 Show InChI InChI=1S/C23H19BrN2O3/c1-28-18-12-16(13-19(29-2)22(18)27)23-25-20(14-6-4-3-5-7-14)21(26-23)15-8-10-17(24)11-9-15/h3-13,27H,1-2H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343393 (CHEMBL1397338 | N-(9-(3,4-dimethoxyphenylamino)-5,...) Show SMILES CCOc1ccccc1C(=O)Nc1ccc2nc3CCCCc3c(Nc3ccc(OC)c(OC)c3)c2c1 Show InChI InChI=1S/C30H31N3O4/c1-4-37-26-12-8-6-10-22(26)30(34)32-19-13-15-25-23(17-19)29(21-9-5-7-11-24(21)33-25)31-20-14-16-27(35-2)28(18-20)36-3/h6,8,10,12-18H,4-5,7,9,11H2,1-3H3,(H,31,33)(H,32,34)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343399 (CHEMBL1609632 | N-[6-(benzylamino)-1,3-dimethyl-2-...) Show SMILES Cn1c2cc(NCc3ccccc3)c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc2n(C)c1=O Show InChI InChI=1S/C26H30N4O3S/c1-26(2,3)19-11-13-20(14-12-19)34(32,33)28-22-16-24-23(29(4)25(31)30(24)5)15-21(22)27-17-18-9-7-6-8-10-18/h6-16,27-28H,17H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208034 (3-((4-Chlorophenyl)thio)-1,5-dimethyl-1H-indole-2-...) Show SMILES Cc1ccc2n(C)c(C(O)=O)c(Sc3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-3-8-14-13(9-10)16(15(17(20)21)19(14)2)22-12-6-4-11(18)5-7-12/h3-9H,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343400 ((4-tert-butyl-6-{2-methyl-5H,6H-pyrazolo[1,5-c]qui...) Show SMILES Cc1cc2-c3ccccc3NC(c3cc(c(O)cc3O)C(C)(C)C)n2n1 Show InChI InChI=1S/C21H23N3O2/c1-12-9-17-13-7-5-6-8-16(13)22-20(24(17)23-12)14-10-15(21(2,3)4)19(26)11-18(14)25/h5-11,20,22,25-26H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343396 (CHEMBL1551959 | ethyl 4-(4-(dimethylamino)phenylam...) Show SMILES CCOC(=O)c1cnc2c(ccc3ccccc23)c1Nc1ccc(cc1)N(C)C Show InChI InChI=1S/C24H23N3O2/c1-4-29-24(28)21-15-25-22-19-8-6-5-7-16(19)9-14-20(22)23(21)26-17-10-12-18(13-11-17)27(2)3/h5-15H,4H2,1-3H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343402 (CHEMBL1599158 | N-(4-(dimethylamino)phenyl)-2-(4-(...) Show SMILES CN(C)c1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)-c2ccco2)cc1 Show InChI InChI=1S/C19H17F3N4O2S/c1-26(2)13-7-5-12(6-8-13)23-17(27)11-29-18-24-14(15-4-3-9-28-15)10-16(25-18)19(20,21)22/h3-10H,11H2,1-2H3,(H,23,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343388 (7-((2-fluorophenyl)(4-methylpyridin-2-ylamino)meth...) Show SMILES Cc1ccnc(NC(c2ccccc2F)c2ccc3cccnc3c2O)c1 Show InChI InChI=1S/C22H18FN3O/c1-14-10-12-24-19(13-14)26-21(16-6-2-3-7-18(16)23)17-9-8-15-5-4-11-25-20(15)22(17)27/h2-13,21,27H,1H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208036 (Methyl 3-((4-chlorophenyl)thio)-1,5-dimethyl-1H-in...) Show SMILES COC(=O)c1c(Sc2ccc(Cl)cc2)c2cc(C)ccc2n1C Show InChI InChI=1S/C18H16ClNO2S/c1-11-4-9-15-14(10-11)17(16(20(15)2)18(21)22-3)23-13-7-5-12(19)6-8-13/h4-10H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.63E+5	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343403 (4-methoxy-N-(1-(2-(4-methoxyphenoxy)ethyl)-1H-benz...) Show SMILES COc1ccc(OCCn2c(NC(=O)c3ccc(OC)cc3)nc3ccccc23)cc1 Show InChI InChI=1S/C24H23N3O4/c1-29-18-9-7-17(8-10-18)23(28)26-24-25-21-5-3-4-6-22(21)27(24)15-16-31-20-13-11-19(30-2)12-14-20/h3-14H,15-16H2,1-2H3,(H,25,26,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.69E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
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Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343411 (CHEMBL1488419 | N-(2-methoxy-5-methylphenyl)-4-met...) Show SMILES COc1ccc(C)cc1N(CC(=O)N1CCC(C)CC1)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C23H30N2O4S/c1-17-5-8-20(9-6-17)30(27,28)25(21-15-19(3)7-10-22(21)29-4)16-23(26)24-13-11-18(2)12-14-24/h5-10,15,18H,11-14,16H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343391 (2-(4-chlorophenyl)-3-hydroxy-6-methyl-4H-chromen-4...) Show SMILES Cc1ccc2oc(-c3ccc(Cl)cc3)c(O)c(=O)c2c1 Show InChI InChI=1S/C16H11ClO3/c1-9-2-7-13-12(8-9)14(18)15(19)16(20-13)10-3-5-11(17)6-4-10/h2-8,19H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343387 (6-chloro-N-(4-fluorophenyl)-2-(pyridin-2-yl)imidaz...) Show SMILES Fc1ccc(Nc2c(nc3ccc(Cl)cn23)-c2ccccn2)cc1 Show InChI InChI=1S/C18H12ClFN4/c19-12-4-9-16-23-17(15-3-1-2-10-21-15)18(24(16)11-12)22-14-7-5-13(20)6-8-14/h1-11,22H	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343389 (6-(2-(4-fluorophenylamino)-4-(4-(pyrrolidin-1-ylsu...) Show SMILES OCCCCCCN1C(Nc2ccc(F)cc2)SC=C1c1ccc(cc1)S(=O)(=O)N1CCCC1 |c:19| Show InChI InChI=1S/C25H32FN3O3S2/c26-21-9-11-22(12-10-21)27-25-29(17-3-1-2-6-18-30)24(19-33-25)20-7-13-23(14-8-20)34(31,32)28-15-4-5-16-28/h7-14,19,25,27,30H,1-6,15-18H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343410 (7-(4-chlorobenzyl)-8-((4-(4-methoxyphenyl)piperazi...) Show SMILES COc1ccc(cc1)N1CCN(Cc2nc3n(C)c(=O)[nH]c(=O)c3n2Cc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H27ClN6O3/c1-29-23-22(24(33)28-25(29)34)32(15-17-3-5-18(26)6-4-17)21(27-23)16-30-11-13-31(14-12-30)19-7-9-20(35-2)10-8-19/h3-10H,11-16H2,1-2H3,(H,28,33,34)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair

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