Compile Data Set for Download or QSAR

Found 173 hits with Last Name = 'cauwenberghs' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Dog)	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS method				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM310197 (US10945994, Compound 2a | US9603836, Compound 2a |...) Show SMILES Fc1ccc2[nH]cc([C@@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312073 (3-(6-bromo-5-fluoro- 1H-indol-3-yl)- pyrrolidine-2...) Show SMILES Fc1cc2c(c[nH]c2cc1Br)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312073 (3-(6-bromo-5-fluoro- 1H-indol-3-yl)- pyrrolidine-2...) Show SMILES Fc1cc2c(c[nH]c2cc1Br)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339961 (5-(6-fluoro-1H-indol-3-yl)-N- methylpyridin-2-amin...) Show SMILES CNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H12FN3/c1-16-14-5-2-9(7-18-14)12-8-17-13-6-10(15)3-4-11(12)13/h2-8,17H,1H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312073 (3-(6-bromo-5-fluoro- 1H-indol-3-yl)- pyrrolidine-2...) Show SMILES Fc1cc2c(c[nH]c2cc1Br)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312076 (3-(5-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...) Show SMILES Brc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339928 (6-fluoro-3-(6-methylpyridin-3- yl)-1H-indole | US9...) Show SMILES Cc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H11FN2/c1-9-2-3-10(7-16-9)13-8-17-14-6-11(15)4-5-12(13)14/h2-8,17H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312076 (3-(5-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...) Show SMILES Brc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312076 (3-(5-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...) Show SMILES Brc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339940 (5-(6-fluoro-1H-indol-3-yl)- N,N-dimethylpyridin-2-...) Show SMILES CN(C)c1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C15H14FN3/c1-19(2)15-6-3-10(8-18-15)13-9-17-14-7-11(16)4-5-12(13)14/h3-9,17H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS method				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312084 (3-(6-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...) Show SMILES Brc1ccc2c(c[nH]c2c1)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312084 (3-(6-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...) Show SMILES Brc1ccc2c(c[nH]c2c1)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312084 (3-(6-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...) Show SMILES Brc1ccc2c(c[nH]c2c1)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312072 (3-(6-chloro-5-fluoro-1H- indol-3-yl)pyrrolidine- 2...) Show SMILES Fc1cc2c(c[nH]c2cc1Cl)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339957 (2-((5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)amino)...) Show SMILES OCCNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C15H14FN3O/c16-11-2-3-12-13(9-18-14(12)7-11)10-1-4-15(19-8-10)17-5-6-20/h1-4,7-9,18,20H,5-6H2,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312072 (3-(6-chloro-5-fluoro-1H- indol-3-yl)pyrrolidine- 2...) Show SMILES Fc1cc2c(c[nH]c2cc1Cl)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312072 (3-(6-chloro-5-fluoro-1H- indol-3-yl)pyrrolidine- 2...) Show SMILES Fc1cc2c(c[nH]c2cc1Cl)C1CC(=O)NC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339941 (4-(5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)morphol...) Show SMILES Fc1ccc2c(c[nH]c2c1)-c1ccc(nc1)N1CCOCC1 Show InChI InChI=1S/C17H16FN3O/c18-13-2-3-14-15(11-19-16(14)9-13)12-1-4-17(20-10-12)21-5-7-22-8-6-21/h1-4,9-11,19H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339955 (N1-(5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)-N2,N2...) Show SMILES CN(C)CCNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C17H19FN4/c1-22(2)8-7-19-17-6-3-12(10-21-17)15-11-20-16-9-13(18)4-5-14(15)16/h3-6,9-11,20H,7-8H2,1-2H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339929 (6-fluoro-3-(6-(piperidin-4- yloxy)pyridin-3-yl)-1H...) Show SMILES Fc1ccc2c(c[nH]c2c1)-c1ccc(OC2CCNCC2)nc1 Show InChI InChI=1S/C18H18FN3O/c19-13-2-3-15-16(11-21-17(15)9-13)12-1-4-18(22-10-12)23-14-5-7-20-8-6-14/h1-4,9-11,14,20-21H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM389161 ((R)-3-(6-chloro-5- fluoro-1H-indol-3-yl) pyrrolidi...) Show SMILES Fc1cc2c(c[nH]c2cc1Cl)[C@H]1CC(=O)NC1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Dog)	BDBM309529 (3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312074 ((R)-3-(6-bromo-5- fluoro-1H-indol-3-yl)- pyrrolidi...) Show SMILES Fc1cc2c(c[nH]c2cc1Br)[C@H]1CC(=O)NC1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere					Assay Description The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...				J Med Chem 52: 646-54 (2009) BindingDB Entry DOI: 10.7270/Q2959KW7
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312074 ((R)-3-(6-bromo-5- fluoro-1H-indol-3-yl)- pyrrolidi...) Show SMILES Fc1cc2c(c[nH]c2cc1Br)[C@H]1CC(=O)NC1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339953 (N-(3-((5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)ami...) Show SMILES CS(=O)(=O)NCCCNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C17H19FN4O2S/c1-25(23,24)22-8-2-7-19-17-6-3-12(10-21-17)15-11-20-16-9-13(18)4-5-14(15)16/h3-6,9-11,20,22H,2,7-8H2,1H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312074 ((R)-3-(6-bromo-5- fluoro-1H-indol-3-yl)- pyrrolidi...) Show SMILES Fc1cc2c(c[nH]c2cc1Br)[C@H]1CC(=O)NC1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
ITEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US9603836 (2017) BindingDB Entry DOI: 10.7270/Q2MK6FZ8
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339950 (5-(6-fluoro-1H-indol-3-yl)-N- (1-(methylsulfonyl)p...) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C19H21FN4O2S/c1-27(25,26)24-8-6-15(7-9-24)23-19-5-2-13(11-22-19)17-12-21-18-10-14(20)3-4-16(17)18/h2-5,10-12,15,21H,6-9H2,1H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339943 (2-amino-1-(4-(5-(6-fluoro-1H- indol-3-yl)pyridin-2...) Show SMILES NCC(=O)N1CCN(CC1)c1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C19H20FN5O/c20-14-2-3-15-16(12-22-17(15)9-14)13-1-4-18(23-11-13)24-5-7-25(8-6-24)19(26)10-21/h1-4,9,11-12,22H,5-8,10,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339956 (N-(2-((5-(6-fluoro-1H-indol-3- yl)pyridin-2-yl)ami...) Show SMILES CS(=O)(=O)NCCNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C16H17FN4O2S/c1-24(22,23)21-7-6-18-16-5-2-11(9-20-16)14-10-19-15-8-12(17)3-4-13(14)15/h2-5,8-10,19,21H,6-7H2,1H3,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339942 (6-fluoro-3-(6-(4- methylpiperazin-1-yl)pyridin- 3-...) Show SMILES CN1CCN(CC1)c1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C18H19FN4/c1-22-6-8-23(9-7-22)18-5-2-13(11-21-18)16-12-20-17-10-14(19)3-4-15(16)17/h2-5,10-12,20H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM310195 ((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...) Show SMILES Fc1ccc2[nH]cc([C@H]3CC(=O)NC3=O)c2c1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc.; iTEOS THERAPEUTICS US Patent					Assay Description To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...				US Patent US10945994 (2021) BindingDB Entry DOI: 10.7270/Q25D8W03
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339938 (6-fluoro-3-(6-methoxypyridin- 3-yl)-1H-indole | US...) Show SMILES COc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C14H11FN2O/c1-18-14-5-2-9(7-17-14)12-8-16-13-6-10(15)3-4-11(12)13/h2-8,16H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339960 (2-((5-(6-fluoro-1H-indol-3- yl)pyridin-2- yl)amino...) Show SMILES NC(=O)CNc1ccc(cn1)-c1c[nH]c2cc(F)ccc12 Show InChI InChI=1S/C15H13FN4O/c16-10-2-3-11-12(7-18-13(11)5-10)9-1-4-15(19-6-9)20-8-14(17)21/h1-7,18H,8H2,(H2,17,21)(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM312069 (3-(5-chloro-1H-indol-3- yl)pyrrolidine-2,5-dione |...) Show SMILES Clc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assay				J Med Chem 60: 9617-9629 (2017) Article DOI: 10.1021/acs.jmedchem.7b00974 BindingDB Entry DOI: 10.7270/Q2ZP48M3
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM339963 (6-fluoro-3-(pyridin-3-yl)-1H- indole | US9758505, ...) Show SMILES Fc1ccc2c(c[nH]c2c1)-c1cccnc1 Show InChI InChI=1S/C13H9FN2/c14-10-3-4-11-12(8-16-13(11)6-10)9-2-1-5-15-7-9/h1-8,16H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
iTeos Therapeutics US Patent					Assay Description The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...				US Patent US9758505 (2017) BindingDB Entry DOI: 10.7270/Q20V8FW9
					More data for this Ligand-Target Pair

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