Compile Data Set for Download or QSAR

Found 194 hits with Last Name = 'yokoi' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130611 (2-Amino-N-{4-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C Show InChI InChI=1S/C26H38N4O4/c1-15-9-19(31)10-16(2)21(15)13-23(27)25(33)29-7-5-6-8-30-26(34)24(28)14-22-17(3)11-20(32)12-18(22)4/h9-12,23-24,31-32H,5-8,13-14,27-28H2,1-4H3,(H,29,33)(H,30,34)/t23-,24+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221787 (CHEMBL3216418) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCc1nc(O)c(CCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C33H46N6O5.2ClH/c1-18-12-23(40)13-19(2)25(18)16-27(34)31(42)36-10-6-8-29-22(5)38-30(33(44)39-29)9-7-11-37-32(43)28(35)17-26-20(3)14-24(41)15-21(26)4;;/h12-15,27-28,40-41H,6-11,16-17,34-35H2,1-5H3,(H,36,42)(H,37,43)(H,39,44);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for Opioid receptor mu 1 agonism in isolated tissues from guinea pig ileum				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130617 (2-Amino-N-{6-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C Show InChI InChI=1S/C28H42N4O4/c1-17-11-21(33)12-18(2)23(17)15-25(29)27(35)31-9-7-5-6-8-10-32-28(36)26(30)16-24-19(3)13-22(34)14-20(24)4/h11-14,25-26,33-34H,5-10,15-16,29-30H2,1-4H3,(H,31,35)(H,32,36)/t25-,26+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149389 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2ncccc12 Show InChI InChI=1S/C34H37N5O4/c1-21-17-24(40)18-22(2)26(21)20-27(35)34(43)39-16-8-14-31(39)33(42)38-30(19-23-9-4-3-5-10-23)32(41)37-29-13-6-12-28-25(29)11-7-15-36-28/h3-7,9-13,15,17-18,27,30-31,40H,8,14,16,19-20,35H2,1-2H3,(H,37,41)(H,38,42)/t27-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221778 (CHEMBL3216392) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1nc(O)c(CCCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C35H50N6O5.2ClH/c1-20-14-25(42)15-21(2)27(20)18-29(36)33(44)38-12-8-6-10-31-24(5)40-32(35(46)41-31)11-7-9-13-39-34(45)30(37)19-28-22(3)16-26(43)17-23(28)4;;/h14-17,29-30,42-43H,6-13,18-19,36-37H2,1-5H3,(H,38,44)(H,39,45)(H,41,46);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards Opioid receptor mu 1 by displacing [3H]DAGO radioligand in rat brain P2 synaptosomes membranes.				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221781 (CHEMBL3215968) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCc1nc(O)c(CCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C31H42N6O5.2ClH/c1-16-10-21(38)11-17(2)23(16)14-25(32)29(40)34-8-6-27-20(5)36-28(31(42)37-27)7-9-35-30(41)26(33)15-24-18(3)12-22(39)13-19(24)4;;/h10-13,25-26,38-39H,6-9,14-15,32-33H2,1-5H3,(H,34,40)(H,35,41)(H,37,42);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for Opioid receptor mu 1 agonism in isolated tissues from guinea pig ileum				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149381 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C25H32N4O4/c1-15-11-18(30)12-16(2)19(15)14-20(26)25(33)29-10-6-9-22(29)24(32)28-21(23(27)31)13-17-7-4-3-5-8-17/h3-5,7-8,11-12,20-22,30H,6,9-10,13-14,26H2,1-2H3,(H2,27,31)(H,28,32)/t20-,21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221423 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(CCc2ccccc2)[nH]c1=O Show InChI InChI=1S/C28H36N4O3/c1-18-15-22(33)16-19(2)23(18)17-24(29)27(34)30-14-8-7-11-26-28(35)32-25(20(3)31-26)13-12-21-9-5-4-6-10-21/h4-6,9-10,15-16,24,33H,7-8,11-14,17,29H2,1-3H3,(H,30,34)(H,32,35)/t24-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149398 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccn1 Show InChI InChI=1S/C30H35N5O4/c1-19-15-22(36)16-20(2)23(19)18-24(31)30(39)35-14-8-11-26(35)29(38)33-25(17-21-9-4-3-5-10-21)28(37)34-27-12-6-7-13-32-27/h3-7,9-10,12-13,15-16,24-26,36H,8,11,14,17-18,31H2,1-2H3,(H,33,38)(H,32,34,37)/t24-,25-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149384 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C34H41N5O5/c1-21-16-25(40)17-22(2)26(21)20-27(35)34(44)39-15-9-14-30(39)33(43)38-29(19-24-12-7-4-8-13-24)32(42)37-28(31(36)41)18-23-10-5-3-6-11-23/h3-8,10-13,16-17,27-30,40H,9,14-15,18-20,35H2,1-2H3,(H2,36,41)(H,37,42)(H,38,43)/t27-,28-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149396 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C30H35N5O4/c1-19-14-23(36)15-20(2)24(19)17-25(31)30(39)35-13-7-11-27(35)29(38)34-26(16-21-8-4-3-5-9-21)28(37)33-22-10-6-12-32-18-22/h3-6,8-10,12,14-15,18,25-27,36H,7,11,13,16-17,31H2,1-2H3,(H,33,37)(H,34,38)/t25-,26-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130619 (2-Amino-N-{8-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C Show InChI InChI=1S/C30H46N4O4/c1-19-13-23(35)14-20(2)25(19)17-27(31)29(37)33-11-9-7-5-6-8-10-12-34-30(38)28(32)18-26-21(3)15-24(36)16-22(26)4/h13-16,27-28,35-36H,5-12,17-18,31-32H2,1-4H3,(H,33,37)(H,34,38)/t27-,28+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149375 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2cnccc12 Show InChI InChI=1S/C34H37N5O4/c1-21-16-25(40)17-22(2)27(21)19-28(35)34(43)39-15-7-12-31(39)33(42)38-30(18-23-8-4-3-5-9-23)32(41)37-29-11-6-10-24-20-36-14-13-26(24)29/h3-6,8-11,13-14,16-17,20,28,30-31,40H,7,12,15,18-19,35H2,1-2H3,(H,37,41)(H,38,42)/t28-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149374 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccc2ncccc2c1 Show InChI InChI=1S/C34H37N5O4/c1-21-16-26(40)17-22(2)27(21)20-28(35)34(43)39-15-7-11-31(39)33(42)38-30(18-23-8-4-3-5-9-23)32(41)37-25-12-13-29-24(19-25)10-6-14-36-29/h3-6,8-10,12-14,16-17,19,28,30-31,40H,7,11,15,18,20,35H2,1-2H3,(H,37,41)(H,38,42)/t28-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149394 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C35H38N4O4/c1-22-18-26(40)19-23(2)28(22)21-29(36)35(43)39-17-9-16-32(39)34(42)38-31(20-24-10-4-3-5-11-24)33(41)37-30-15-8-13-25-12-6-7-14-27(25)30/h3-8,10-15,18-19,29,31-32,40H,9,16-17,20-21,36H2,1-2H3,(H,37,41)(H,38,42)/t29-,31-,32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149386 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C34H37N5O4/c1-21-15-26(40)16-22(2)27(21)19-28(35)34(43)39-14-8-13-31(39)33(42)38-30(17-23-9-4-3-5-10-23)32(41)37-25-18-24-11-6-7-12-29(24)36-20-25/h3-7,9-12,15-16,18,20,28,30-31,40H,8,13-14,17,19,35H2,1-2H3,(H,37,41)(H,38,42)/t28-,30-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149378 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccncc1 Show InChI InChI=1S/C30H35N5O4/c1-19-15-23(36)16-20(2)24(19)18-25(31)30(39)35-14-6-9-27(35)29(38)34-26(17-21-7-4-3-5-8-21)28(37)33-22-10-12-32-13-11-22/h3-5,7-8,10-13,15-16,25-27,36H,6,9,14,17-18,31H2,1-2H3,(H,34,38)(H,32,33,37)/t25-,26-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130613 (2-Amino-N-{4-[2-amino-3-(4-hydroxy-phenyl)-propion...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCNC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C24H34N4O4/c1-15-11-19(30)12-16(2)20(15)14-22(26)24(32)28-10-4-3-9-27-23(31)21(25)13-17-5-7-18(29)8-6-17/h5-8,11-12,21-22,29-30H,3-4,9-10,13-14,25-26H2,1-2H3,(H,27,31)(H,28,32)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221419 ((S)-2-amino-N-(4-(5-benzyl-6-methyl-3-oxo-3,4-dihy...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(Cc2ccccc2)[nH]c1=O Show InChI InChI=1S/C27H34N4O3/c1-17-13-21(32)14-18(2)22(17)16-23(28)26(33)29-12-8-7-11-24-27(34)31-25(19(3)30-24)15-20-9-5-4-6-10-20/h4-6,9-10,13-14,23,32H,7-8,11-12,15-16,28H2,1-3H3,(H,29,33)(H,31,34)/t23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149382 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C34H37N5O4/c1-21-17-25(40)18-22(2)26(21)20-27(35)34(43)39-16-8-14-30(39)33(42)38-29(19-23-9-4-3-5-10-23)32(41)37-28-13-6-11-24-12-7-15-36-31(24)28/h3-7,9-13,15,17-18,27,29-30,40H,8,14,16,19-20,35H2,1-2H3,(H,37,41)(H,38,42)/t27-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149385 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C33H40N4O4/c1-22-18-26(38)19-23(2)27(22)21-28(34)33(41)37-17-9-14-30(37)32(40)36-29(20-25-12-7-4-8-13-25)31(39)35-16-15-24-10-5-3-6-11-24/h3-8,10-13,18-19,28-30,38H,9,14-17,20-21,34H2,1-2H3,(H,35,39)(H,36,40)/t28-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149376 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C32H38N4O4/c1-21-16-25(37)17-22(2)26(21)19-27(33)32(40)36-15-9-14-29(36)31(39)35-28(18-23-10-5-3-6-11-23)30(38)34-20-24-12-7-4-8-13-24/h3-8,10-13,16-17,27-29,37H,9,14-15,18-20,33H2,1-2H3,(H,34,38)(H,35,39)/t27-,28-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130612 (2-Amino-N-[4-(2-amino-3-phenyl-propionylamino)-but...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCNC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C24H34N4O3/c1-16-12-19(29)13-17(2)20(16)15-22(26)24(31)28-11-7-6-10-27-23(30)21(25)14-18-8-4-3-5-9-18/h3-5,8-9,12-13,21-22,29H,6-7,10-11,14-15,25-26H2,1-2H3,(H,27,30)(H,28,31)/t21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221429 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(3-...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(CCc2ccccc2)[nH]c1=O Show InChI InChI=1S/C27H34N4O3/c1-17-14-21(32)15-18(2)22(17)16-23(28)26(33)29-13-7-10-25-27(34)31-24(19(3)30-25)12-11-20-8-5-4-6-9-20/h4-6,8-9,14-15,23,32H,7,10-13,16,28H2,1-3H3,(H,29,33)(H,31,34)/t23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221420 ((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-...) Show SMILES Cc1c[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)n1 Show InChI InChI=1S/C20H28N4O3/c1-12-8-15(25)9-13(2)16(12)10-17(21)19(26)22-7-5-4-6-18-20(27)23-11-14(3)24-18/h8-9,11,17,25H,4-7,10,21H2,1-3H3,(H,22,26)(H,23,27)/t17-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221418 ((S)-N-(4-(5-(2,6-dimethylbenzyl)-6-methyl-3-oxo-3,...) Show SMILES Cc1cccc(C)c1Cc1[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C29H38N4O3/c1-17-9-8-10-18(2)24(17)16-27-21(5)32-26(29(36)33-27)11-6-7-12-31-28(35)25(30)15-23-19(3)13-22(34)14-20(23)4/h8-10,13-14,25,34H,6-7,11-12,15-16,30H2,1-5H3,(H,31,35)(H,33,36)/t25-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50139013 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221424 ((S)-2-amino-N-(3-(5-benzyl-6-methyl-3-oxo-3,4-dihy...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(Cc2ccccc2)[nH]c1=O Show InChI InChI=1S/C26H32N4O3/c1-16-12-20(31)13-17(2)21(16)15-22(27)25(32)28-11-7-10-23-26(33)30-24(18(3)29-23)14-19-8-5-4-6-9-19/h4-6,8-9,12-13,22,31H,7,10-11,14-15,27H2,1-3H3,(H,28,32)(H,30,33)/t22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149391 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C31H36N4O4/c1-20-16-24(36)17-21(2)25(20)19-26(32)31(39)35-15-9-14-28(35)30(38)34-27(18-22-10-5-3-6-11-22)29(37)33-23-12-7-4-8-13-23/h3-8,10-13,16-17,26-28,36H,9,14-15,18-19,32H2,1-2H3,(H,33,37)(H,34,38)/t26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221780 (CHEMBL3217089) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCc1nc(O)c(CNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C29H38N6O5.2ClH/c1-14-6-19(36)7-15(2)21(14)10-23(30)27(38)32-12-25-18(5)34-26(29(40)35-25)13-33-28(39)24(31)11-22-16(3)8-20(37)9-17(22)4;;/h6-9,23-24,36-37H,10-13,30-31H2,1-5H3,(H,32,38)(H,33,39)(H,35,40);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards Opioid receptor mu 1 by displacing [3H]DAGO radioligand in rat brain P2 synaptosomes membranes.				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130614 (2-Amino-N-{2-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C Show InChI InChI=1S/C24H34N4O4/c1-13-7-17(29)8-14(2)19(13)11-21(25)23(31)27-5-6-28-24(32)22(26)12-20-15(3)9-18(30)10-16(20)4/h7-10,21-22,29-30H,5-6,11-12,25-26H2,1-4H3,(H,27,31)(H,28,32)/t21-,22+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149377 (1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyr...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C33H34N4O4/c34-27(20-23-15-17-25(38)18-16-23)33(41)37-19-7-14-30(37)32(40)36-29(21-22-8-2-1-3-9-22)31(39)35-28-13-6-11-24-10-4-5-12-26(24)28/h1-6,8-13,15-18,27,29-30,38H,7,14,19-21,34H2,(H,35,39)(H,36,40)/t27-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149402 (1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyr...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2ncccc12 Show InChI InChI=1S/C32H33N5O4/c33-25(19-22-13-15-23(38)16-14-22)32(41)37-18-6-12-29(37)31(40)36-28(20-21-7-2-1-3-8-21)30(39)35-27-11-4-10-26-24(27)9-5-17-34-26/h1-5,7-11,13-17,25,28-29,38H,6,12,18-20,33H2,(H,35,39)(H,36,40)/t25-,28-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221428 ((S)-2-amino-N-(4-(5,6-dimethyl-3-oxo-3,4-dihydropy...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(C)[nH]c1=O Show InChI InChI=1S/C21H30N4O3/c1-12-9-16(26)10-13(2)17(12)11-18(22)20(27)23-8-6-5-7-19-21(28)25-15(4)14(3)24-19/h9-10,18,26H,5-8,11,22H2,1-4H3,(H,23,27)(H,25,28)/t18-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50221418 ((S)-N-(4-(5-(2,6-dimethylbenzyl)-6-methyl-3-oxo-3,...) Show SMILES Cc1cccc(C)c1Cc1[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C29H38N4O3/c1-17-9-8-10-18(2)24(17)16-27-21(5)32-26(29(36)33-27)11-6-7-12-31-28(35)25(30)15-23-19(3)13-22(34)14-20(23)4/h8-10,13-14,25,34H,6-7,11-12,15-16,30H2,1-5H3,(H,31,35)(H,33,36)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin 2 from delta opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149397 (1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyr...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C29H38N4O4/c30-24(18-21-13-15-23(34)16-14-21)29(37)33-17-7-12-26(33)28(36)32-25(19-20-8-3-1-4-9-20)27(35)31-22-10-5-2-6-11-22/h1,3-4,8-9,13-16,22,24-26,34H,2,5-7,10-12,17-19,30H2,(H,31,35)(H,32,36)/t24-,25-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149379 (1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyr...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NC1C2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |wU:20.21,38.40,1.0,wD:16.18,34.43,36.39,TLB:39:38:40:34.33.35,30:31:33:36.40.35,30:31:40:34.33.35,THB:35:34:31:36.37.40,35:36:31:34.33.39,37:38:33:36.40.35,(-1.86,-8.18,;-1.85,-9.72,;-.51,-10.48,;.8,-9.72,;.8,-8.16,;2.13,-7.39,;3.48,-8.16,;4.8,-7.39,;3.48,-9.71,;2.15,-10.48,;-3.19,-10.48,;-4.52,-9.73,;-3.18,-12.04,;-4.42,-12.95,;-3.95,-14.41,;-2.41,-14.39,;-1.93,-12.93,;-.47,-12.45,;.45,-11.09,;.68,-13.49,;2.14,-13,;2.45,-11.48,;3.92,-11.01,;4.24,-9.51,;5.7,-9.02,;6.85,-10.04,;6.53,-11.55,;5.06,-12.04,;3.29,-14.02,;2.98,-15.53,;4.75,-13.53,;6.25,-13.22,;6.82,-11.9,;7.01,-13.51,;8.19,-14.58,;9.57,-13.93,;9.31,-12.31,;8.62,-13.58,;7.36,-14.22,;7.48,-15.98,;8.19,-11.27,)| Show InChI InChI=1S/C33H42N4O4/c34-27(18-21-8-10-26(38)11-9-21)33(41)37-12-4-7-29(37)32(40)35-28(19-20-5-2-1-3-6-20)31(39)36-30-24-14-22-13-23(16-24)17-25(30)15-22/h1-3,5-6,8-11,22-25,27-30,38H,4,7,12-19,34H2,(H,35,40)(H,36,39)/t22-,23+,24-,25?,27-,28-,29-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50221781 (CHEMBL3215968) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCc1nc(O)c(CCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C31H42N6O5.2ClH/c1-16-10-21(38)11-17(2)23(16)14-25(32)29(40)34-8-6-27-20(5)36-28(31(42)37-27)7-9-35-30(41)26(33)15-24-18(3)12-22(39)13-19(24)4;;/h10-13,25-26,38-39H,6-9,14-15,32-33H2,1-5H3,(H,34,40)(H,35,41)(H,37,42);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards opioid receptor delta 1 by displacing [3H]DPDPE radioligand in rat brain P2 synaptosomes membranes.				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50221419 ((S)-2-amino-N-(4-(5-benzyl-6-methyl-3-oxo-3,4-dihy...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(Cc2ccccc2)[nH]c1=O Show InChI InChI=1S/C27H34N4O3/c1-17-13-21(32)14-18(2)22(17)16-23(28)26(33)29-12-8-7-11-24-27(34)31-25(19(3)30-24)15-20-9-5-4-6-10-20/h4-6,9-10,13-14,23,32H,7-8,11-12,15-16,28H2,1-3H3,(H,29,33)(H,31,34)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin 2 from delta opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221422 ((S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropy...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(C)[nH]c1=O Show InChI InChI=1S/C20H28N4O3/c1-11-8-15(25)9-12(2)16(11)10-17(21)19(26)22-7-5-6-18-20(27)24-14(4)13(3)23-18/h8-9,17,25H,5-7,10,21H2,1-4H3,(H,22,26)(H,24,27)/t17-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149399 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C31H36N4O4/c32-26(20-24-13-15-25(36)16-14-24)31(39)35-19-7-12-28(35)30(38)34-27(21-23-10-5-2-6-11-23)29(37)33-18-17-22-8-3-1-4-9-22/h1-6,8-11,13-16,26-28,36H,7,12,17-21,32H2,(H,33,37)(H,34,38)/t26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50221787 (CHEMBL3216418) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCc1nc(O)c(CCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C33H46N6O5.2ClH/c1-18-12-23(40)13-19(2)25(18)16-27(34)31(42)36-10-6-8-29-22(5)38-30(33(44)39-29)9-7-11-37-32(43)28(35)17-26-20(3)14-24(41)15-21(26)4;;/h12-15,27-28,40-41H,6-11,16-17,34-35H2,1-5H3,(H,36,42)(H,37,43)(H,39,44);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description pA2 is the negative log of the molar concentration required to double the agonism of opioid receptor delta 1				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50149376 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C32H38N4O4/c1-21-16-25(37)17-22(2)26(21)19-27(33)32(40)36-15-9-14-29(36)31(39)35-28(18-23-10-5-3-6-11-23)30(38)34-20-24-12-7-4-8-13-24/h3-8,10-13,16-17,27-29,37H,9,14-15,18-20,33H2,1-2H3,(H,34,38)(H,35,39)/t27-,28-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain opioid receptor delta 1 using [3H]-DPDPE radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221425 ((S)-2-amino-N-(4-(3,5-dimethyl-6-oxo-1,6-dihydropy...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1[nH]c(=O)c(C)nc1C Show InChI InChI=1S/C21H30N4O3/c1-12-9-16(26)10-13(2)17(12)11-18(22)21(28)23-8-6-5-7-19-14(3)24-15(4)20(27)25-19/h9-10,18,26H,5-8,11,22H2,1-4H3,(H,23,28)(H,25,27)/t18-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor				Bioorg Med Chem Lett 17: 5768-71 (2007) Article DOI: 10.1016/j.bmcl.2007.08.058 BindingDB Entry DOI: 10.7270/Q2N29WPB
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50130619 (2-Amino-N-{8-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C Show InChI InChI=1S/C30H46N4O4/c1-19-13-23(35)14-20(2)25(19)17-27(31)29(37)33-11-9-7-5-6-8-10-12-34-30(38)28(32)18-26-21(3)15-24(36)16-22(26)4/h13-16,27-28,35-36H,5-12,17-18,31-32H2,1-4H3,(H,33,37)(H,34,38)/t27-,28+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50221780 (CHEMBL3217089) Show SMILES Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCc1nc(O)c(CNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C Show InChI InChI=1S/C29H38N6O5.2ClH/c1-14-6-19(36)7-15(2)21(14)10-23(30)27(38)32-12-25-18(5)34-26(29(40)35-25)13-33-28(39)24(31)11-22-16(3)8-20(37)9-17(22)4;;/h6-9,23-24,36-37H,10-13,30-31H2,1-5H3,(H,32,38)(H,33,39)(H,35,40);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards opioid receptor delta 1 by displacing [3H]DPDPE radioligand in rat brain P2 synaptosomes membranes.				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50149385 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C33H40N4O4/c1-22-18-26(38)19-23(2)27(22)21-28(34)33(41)37-17-9-14-30(37)32(40)36-29(20-25-12-7-4-8-13-25)31(39)35-16-15-24-10-5-3-6-11-24/h3-8,10-13,18-19,28-30,38H,9,14-17,20-21,34H2,1-2H3,(H,35,39)(H,36,40)/t28-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain opioid receptor delta 1 using [3H]-DPDPE radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50149383 (1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyr...) Show SMILES CC(C)(C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C27H36N4O4/c1-27(2,3)30-24(33)22(17-18-8-5-4-6-9-18)29-25(34)23-10-7-15-31(23)26(35)21(28)16-19-11-13-20(32)14-12-19/h4-6,8-9,11-14,21-23,32H,7,10,15-17,28H2,1-3H3,(H,29,34)(H,30,33)/t21-,22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50149394 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C35H38N4O4/c1-22-18-26(40)19-23(2)28(22)21-29(36)35(43)39-17-9-16-32(39)34(42)38-31(20-24-10-4-3-5-11-24)33(41)37-30-15-8-13-25-12-6-7-14-27(25)30/h3-8,10-15,18-19,29,31-32,40H,9,16-17,20-21,36H2,1-2H3,(H,37,41)(H,38,42)/t29-,31-,32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain opioid receptor delta 1 using [3H]-DPDPE radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50149391 (1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C31H36N4O4/c1-20-16-24(36)17-21(2)25(20)19-26(32)31(39)35-15-9-14-28(35)30(38)34-27(18-22-10-5-3-6-11-22)29(37)33-23-12-7-4-8-13-23/h3-8,10-13,16-17,26-28,36H,9,14-15,18-19,32H2,1-2H3,(H,33,37)(H,34,38)/t26-,27-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity against rat brain opioid receptor delta 1 using [3H]-DPDPE radioligand				J Med Chem 47: 3591-9 (2004) Article DOI: 10.1021/jm030649p BindingDB Entry DOI: 10.7270/Q2W095DJ
					More data for this Ligand-Target Pair

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