Compile Data Set for Download or QSAR

Found 338 hits with Last Name = 'garzya' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50347782 (CHEMBL1802360) Show SMILES Fc1ccc(OCCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1 Show InChI InChI=1S/C21H24FN3O2/c22-16-6-8-18(9-7-16)27-15-3-12-24-13-10-17(11-14-24)25-20-5-2-1-4-19(20)23-21(25)26/h1-2,4-9,17H,3,10-15H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to dopamine D2 receptor				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50347782 (CHEMBL1802360) Show SMILES Fc1ccc(OCCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1 Show InChI InChI=1S/C21H24FN3O2/c22-16-6-8-18(9-7-16)27-15-3-12-24-13-10-17(11-14-24)25-20-5-2-1-4-19(20)23-21(25)26/h1-2,4-9,17H,3,10-15H2,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to dopamine D3 receptor				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50347782 (CHEMBL1802360) Show SMILES Fc1ccc(OCCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1 Show InChI InChI=1S/C21H24FN3O2/c22-16-6-8-18(9-7-16)27-15-3-12-24-13-10-17(11-14-24)25-20-5-2-1-4-19(20)23-21(25)26/h1-2,4-9,17H,3,10-15H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50391743 (CHEMBL2146597) Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C18H25N3O/c22-18-19-16-8-4-5-9-17(16)21(18)15-10-12-20(13-11-15)14-6-2-1-3-7-14/h4-5,8-9,14-15H,1-3,6-7,10-13H2,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to dopamine D3 receptor				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50391743 (CHEMBL2146597) Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C18H25N3O/c22-18-19-16-8-4-5-9-17(16)21(18)15-10-12-20(13-11-15)14-6-2-1-3-7-14/h4-5,8-9,14-15H,1-3,6-7,10-13H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to dopamine D2 receptor				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50391743 (CHEMBL2146597) Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C18H25N3O/c22-18-19-16-8-4-5-9-17(16)21(18)15-10-12-20(13-11-15)14-6-2-1-3-7-14/h4-5,8-9,14-15H,1-3,6-7,10-13H2,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416151 (CHEMBL1084850) Show SMILES OC(CCC1CCNCC1)c1ccccc1-c1cccc(Cl)c1 Show InChI InChI=1S/C20H24ClNO/c21-17-5-3-4-16(14-17)18-6-1-2-7-19(18)20(23)9-8-15-10-12-22-13-11-15/h1-7,14-15,20,22-23H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483163 (CHEMBL1630067) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(nn2c1C)-c1cccs1 Show InChI InChI=1S/C18H16N4O3S/c1-11-15(12(2)24-18(23)19-13-7-4-3-5-8-13)25-17-20-16(21-22(11)17)14-9-6-10-26-14/h3-10,12H,1-2H3,(H,19,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483149 (CHEMBL1630065) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(Cl)nn2c1C Show InChI InChI=1S/C14H13ClN4O3/c1-8-11(22-13-17-12(15)18-19(8)13)9(2)21-14(20)16-10-6-4-3-5-7-10/h3-7,9H,1-2H3,(H,16,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483151 (CHEMBL1630068) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(nn2c1C)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17FN4O3/c1-12-17(13(2)27-20(26)22-16-6-4-3-5-7-16)28-19-23-18(24-25(12)19)14-8-10-15(21)11-9-14/h3-11,13H,1-2H3,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416152 (CHEMBL1084851) Show SMILES Clc1cccc(c1)-c1ccccc1\C=C\CC1CCNCC1 Show InChI InChI=1S/C20H22ClN/c21-19-9-4-8-18(15-19)20-10-2-1-6-17(20)7-3-5-16-11-13-22-14-12-16/h1-4,6-10,15-16,22H,5,11-14H2/b7-3+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483150 (CHEMBL1630066) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(nn2c1C)C1CC1 Show InChI InChI=1S/C17H18N4O3/c1-10-14(24-16-19-15(12-8-9-12)20-21(10)16)11(2)23-17(22)18-13-6-4-3-5-7-13/h3-7,11-12H,8-9H2,1-2H3,(H,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483155 (CHEMBL1630076) Show SMILES CC(OC(=O)Nc1ccccc1)c1sc2nccn2c1C Show InChI InChI=1S/C15H15N3O2S/c1-10-13(21-14-16-8-9-18(10)14)11(2)20-15(19)17-12-6-4-3-5-7-12/h3-9,11H,1-2H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416164 (CHEMBL1083402) Show SMILES Clc1cccc(c1)-c1ccccc1S(=O)(=O)CCC1CCNCC1 Show InChI InChI=1S/C19H22ClNO2S/c20-17-5-3-4-16(14-17)18-6-1-2-7-19(18)24(22,23)13-10-15-8-11-21-12-9-15/h1-7,14-15,21H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Mus musculus)	BDBM50483145 (CHEMBL1630080) Show SMILES C[C@@H](OC(=O)Nc1cccc(F)c1)c1sc2nncn2c1C |r| Show InChI InChI=1S/C14H13FN4O2S/c1-8-12(22-13-18-16-7-19(8)13)9(2)21-14(20)17-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,17,20)/t9-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assay				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Mus musculus)	BDBM50483144 (CHEMBL1630057 | GSK2210875) Show SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C |r| Show InChI InChI=1S/C14H14N4O2S/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)/t10-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assay				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416141 (CHEMBL1083925) Show SMILES C[C@H]1CNCC[C@@H]1CNC(=O)c1c(F)cccc1-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H22ClFN2O/c1-13-11-23-9-8-15(13)12-24-20(25)19-17(6-3-7-18(19)22)14-4-2-5-16(21)10-14/h2-7,10,13,15,23H,8-9,11-12H2,1H3,(H,24,25)/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483153 (CHEMBL1630070) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(nn2c1C)C(F)(F)F Show InChI InChI=1S/C15H13F3N4O3/c1-8-11(25-13-20-12(15(16,17)18)21-22(8)13)9(2)24-14(23)19-10-6-4-3-5-7-10/h3-7,9H,1-2H3,(H,19,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483152 (CHEMBL1630069) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(C)nn2c1C Show InChI InChI=1S/C15H16N4O3/c1-9-13(22-14-16-11(3)18-19(9)14)10(2)21-15(20)17-12-7-5-4-6-8-12/h4-8,10H,1-3H3,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483147 (CHEMBL1630061) Show SMILES CC(OC(=O)Nc1cccc(Cl)c1)c1oc2ncnn2c1C Show InChI InChI=1S/C14H13ClN4O3/c1-8-12(22-13-16-7-17-19(8)13)9(2)21-14(20)18-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483144 (CHEMBL1630057 | GSK2210875) Show SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C |r| Show InChI InChI=1S/C14H14N4O2S/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483145 (CHEMBL1630080) Show SMILES C[C@@H](OC(=O)Nc1cccc(F)c1)c1sc2nncn2c1C |r| Show InChI InChI=1S/C14H13FN4O2S/c1-8-12(22-13-18-16-7-19(8)13)9(2)21-14(20)17-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,17,20)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483160 (CHEMBL1630064) Show SMILES CC(OC(=O)Nc1cccc(F)c1)c1oc2ncnn2c1C Show InChI InChI=1S/C14H13FN4O3/c1-8-12(22-13-16-7-17-19(8)13)9(2)21-14(20)18-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483157 (CHEMBL1630079) Show SMILES CC(OC(=O)Nc1cccc(F)c1)c1sc2nncn2c1C Show InChI InChI=1S/C14H13FN4O2S/c1-8-12(22-13-18-16-7-19(8)13)9(2)21-14(20)17-11-5-3-4-10(15)6-11/h3-7,9H,1-2H3,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483146 (CHEMBL1630059) Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2ncnn2c1C Show InChI InChI=1S/C14H14N4O3/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50347782 (CHEMBL1802360) Show SMILES Fc1ccc(OCCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1 Show InChI InChI=1S/C21H24FN3O2/c22-16-6-8-18(9-7-16)27-15-3-12-24-13-10-17(11-14-24)25-20-5-2-1-4-19(20)23-21(25)26/h1-2,4-9,17H,3,10-15H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to human ERG				ACS Med Chem Lett 1: 244-248 (2010) Article DOI: 10.1021/ml100105x BindingDB Entry DOI: 10.7270/Q20R9QGK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416159 (CHEMBL1084804) Show SMILES Clc1cccc(c1)-c1ccccc1CC(=O)NC1CCNCC1 Show InChI InChI=1S/C19H21ClN2O/c20-16-6-3-5-14(12-16)18-7-2-1-4-15(18)13-19(23)22-17-8-10-21-11-9-17/h1-7,12,17,21H,8-11,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483158 (CHEMBL1630077) Show SMILES CC(OC(=O)Nc1ccccc1)c1sc2nncn2c1C Show InChI InChI=1S/C14H14N4O2S/c1-9-12(21-13-17-15-8-18(9)13)10(2)20-14(19)16-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50416141 (CHEMBL1083925) Show SMILES C[C@H]1CNCC[C@@H]1CNC(=O)c1c(F)cccc1-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H22ClFN2O/c1-13-11-23-9-8-15(13)12-24-20(25)19-17(6-3-7-18(19)22)14-4-2-5-16(21)10-14/h2-7,10,13,15,23H,8-9,11-12H2,1H3,(H,24,25)/t13-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M4 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50416141 (CHEMBL1083925) Show SMILES C[C@H]1CNCC[C@@H]1CNC(=O)c1c(F)cccc1-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H22ClFN2O/c1-13-11-23-9-8-15(13)12-24-20(25)19-17(6-3-7-18(19)22)14-4-2-5-16(21)10-14/h2-7,10,13,15,23H,8-9,11-12H2,1H3,(H,24,25)/t13-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416240 (CHEMBL1083723) Show SMILES Cc1ccc(cc1Cl)-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C20H23ClN2O/c1-14-6-7-16(12-19(14)21)17-4-2-3-5-18(17)20(24)23-13-15-8-10-22-11-9-15/h2-7,12,15,22H,8-11,13H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483156 (CHEMBL1630078) Show SMILES CC(OC(=O)Nc1cccnc1)c1sc2ncnn2c1C Show InChI InChI=1S/C13H13N5O2S/c1-8-11(21-12-15-7-16-18(8)12)9(2)20-13(19)17-10-4-3-5-14-6-10/h3-7,9H,1-2H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50416240 (CHEMBL1083723) Show SMILES Cc1ccc(cc1Cl)-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C20H23ClN2O/c1-14-6-7-16(12-19(14)21)17-4-2-3-5-18(17)20(24)23-13-15-8-10-22-11-9-15/h2-7,12,15,22H,8-11,13H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M4 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50416240 (CHEMBL1083723) Show SMILES Cc1ccc(cc1Cl)-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C20H23ClN2O/c1-14-6-7-16(12-19(14)21)17-4-2-3-5-18(17)20(24)23-13-15-8-10-22-11-9-15/h2-7,12,15,22H,8-11,13H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES CCCCc1ccc(cc1)S(=O)(=O)Nc1ccc2CCN(C)CCc2c1 Show InChI InChI=1S/C21H28N2O2S/c1-3-4-5-17-6-10-21(11-7-17)26(24,25)22-20-9-8-18-12-14-23(2)15-13-19(18)16-20/h6-11,16,22H,3-5,12-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP2C19				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483166 (CHEMBL1630060) Show SMILES CC(OC(=O)Nc1ccccc1Cl)c1oc2ncnn2c1C Show InChI InChI=1S/C14H13ClN4O3/c1-8-12(22-13-16-7-17-19(8)13)9(2)21-14(20)18-11-6-4-3-5-10(11)15/h3-7,9H,1-2H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50416141 (CHEMBL1083925) Show SMILES C[C@H]1CNCC[C@@H]1CNC(=O)c1c(F)cccc1-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H22ClFN2O/c1-13-11-23-9-8-15(13)12-24-20(25)19-17(6-3-7-18(19)22)14-4-2-5-16(21)10-14/h2-7,10,13,15,23H,8-9,11-12H2,1H3,(H,24,25)/t13-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50416240 (CHEMBL1083723) Show SMILES Cc1ccc(cc1Cl)-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C20H23ClN2O/c1-14-6-7-16(12-19(14)21)17-4-2-3-5-18(17)20(24)23-13-15-8-10-22-11-9-15/h2-7,12,15,22H,8-11,13H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416244 (CHEMBL1083108) Show SMILES Fc1ccc(Cl)cc1-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C19H20ClFN2O/c20-14-5-6-18(21)17(11-14)15-3-1-2-4-16(15)19(24)23-12-13-7-9-22-10-8-13/h1-6,11,13,22H,7-10,12H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416249 (CHEMBL1084993) Show SMILES CC1CNCCC1CNC(=O)c1ccccc1-c1cccc(Cl)c1 Show InChI InChI=1S/C20H23ClN2O/c1-14-12-22-10-9-16(14)13-23-20(24)19-8-3-2-7-18(19)15-5-4-6-17(21)11-15/h2-8,11,14,16,22H,9-10,12-13H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416142 (CHEMBL1083404) Show SMILES Fc1cccc(-c2cc(Cl)ccc2Cl)c1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C19H19Cl2FN2O/c20-13-4-5-16(21)15(10-13)14-2-1-3-17(22)18(14)19(25)24-11-12-6-8-23-9-7-12/h1-5,10,12,23H,6-9,11H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50416140 (CHEMBL1083618) Show SMILES Fc1cccc(-c2cccc(Cl)c2)c1C(=O)NCC1=CCNCC1 |t:20| Show InChI InChI=1S/C19H18ClFN2O/c20-15-4-1-3-14(11-15)16-5-2-6-17(21)18(16)19(24)23-12-13-7-9-22-10-8-13/h1-7,11,22H,8-10,12H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416150 (CHEMBL1085985) Show SMILES Fc1cccc(-c2cccc(Cl)c2)c1C(=O)NCC1(F)CCNCC1 Show InChI InChI=1S/C19H19ClF2N2O/c20-14-4-1-3-13(11-14)15-5-2-6-16(21)17(15)18(25)24-12-19(22)7-9-23-10-8-19/h1-6,11,23H,7-10,12H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50197858 (4'-chloro-biphenyl-4-sulfonic acid (3-methyl-2,3,4...) Show SMILES CN1CCc2ccc(NS(=O)(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 Show InChI InChI=1S/C23H23ClN2O2S/c1-26-14-12-19-4-9-22(16-20(19)13-15-26)25-29(27,28)23-10-5-18(6-11-23)17-2-7-21(24)8-3-17/h2-11,16,25H,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50416140 (CHEMBL1083618) Show SMILES Fc1cccc(-c2cccc(Cl)c2)c1C(=O)NCC1=CCNCC1 |t:20| Show InChI InChI=1S/C19H18ClFN2O/c20-15-4-1-3-14(11-15)16-5-2-6-17(21)18(16)19(24)23-12-13-7-9-22-10-8-13/h1-7,11,22H,8-10,12H2,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50416244 (CHEMBL1083108) Show SMILES Fc1ccc(Cl)cc1-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C19H20ClFN2O/c20-14-5-6-18(21)17(11-14)15-3-1-2-4-16(15)19(24)23-12-13-7-9-22-10-8-13/h1-6,11,13,22H,7-10,12H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M4 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50197859 (4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]...) Show SMILES CCCCc1ccc(cc1)S(=O)(=O)Nc1ccc2CCN(C)CCc2c1 Show InChI InChI=1S/C21H28N2O2S/c1-3-4-5-17-6-10-21(11-7-17)26(24,25)22-20-9-8-18-12-14-23(2)15-13-19(18)16-20/h6-11,16,22H,3-5,12-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
UK. Vinc Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 17: 400-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.036 BindingDB Entry DOI: 10.7270/Q2668CVB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416157 (CHEMBL1085556) Show SMILES Clc1cccc(c1)-c1ccccc1CNC(=O)C1CCNCC1 Show InChI InChI=1S/C19H21ClN2O/c20-17-6-3-5-15(12-17)18-7-2-1-4-16(18)13-22-19(23)14-8-10-21-11-9-14/h1-7,12,14,21H,8-11,13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50416244 (CHEMBL1083108) Show SMILES Fc1ccc(Cl)cc1-c1ccccc1C(=O)NCC1CCNCC1 Show InChI InChI=1S/C19H20ClFN2O/c20-14-5-6-18(21)17(11-14)15-3-1-2-4-16(15)19(24)23-12-13-7-9-22-10-8-13/h1-6,11,13,22H,7-10,12H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3540-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.128 BindingDB Entry DOI: 10.7270/Q2KP83DF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50416145 (CHEMBL1083926) Show SMILES C[C@H]1CNCC[C@H]1CNC(=O)c1c(F)cccc1-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H22ClFN2O/c1-13-11-23-9-8-15(13)12-24-20(25)19-17(6-3-7-18(19)22)14-4-2-5-16(21)10-14/h2-7,10,13,15,23H,8-9,11-12H2,1H3,(H,24,25)/t13-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 3545-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.127 BindingDB Entry DOI: 10.7270/Q2QF8V4S
					More data for this Ligand-Target Pair

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