Compile Data Set for Download or QSAR

Found 70 hits with Last Name = 'bergmann' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032539 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((Z)-styryl...) Show SMILES CN1C2CCC1[C@@H](\C=C/c1ccccc1)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.15.16:4.3| Show InChI InChI=1S/C22H24ClN/c1-24-19-12-14-22(24)20(13-7-16-5-3-2-4-6-16)21(15-19)17-8-10-18(23)11-9-17/h2-11,13,19-22H,12,14-15H2,1H3/b13-7-/t19?,20-,21+,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding constant for the ability to displace [3H]mazindol to dopamine receptor was calculated from the Cheng-Prusoff relationship				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032536 ((2R,3S)-3-(4-Chloro-phenyl)-2-((Z)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C/Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8-/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032539 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((Z)-styryl...) Show SMILES CN1C2CCC1[C@@H](\C=C/c1ccccc1)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.15.16:4.3| Show InChI InChI=1S/C22H24ClN/c1-24-19-12-14-22(24)20(13-7-16-5-3-2-4-6-16)21(15-19)17-8-10-18(23)11-9-17/h2-11,13,19-22H,12,14-15H2,1H3/b13-7-/t19?,20-,21+,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032534 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((E)-styryl...) Show SMILES CN1C2CCC1[C@@H](\C=C\c1ccccc1)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.15.16:4.3| Show InChI InChI=1S/C22H24ClN/c1-24-19-12-14-22(24)20(13-7-16-5-3-2-4-6-16)21(15-19)17-8-10-18(23)11-9-17/h2-11,13,19-22H,12,14-15H2,1H3/b13-7+/t19?,20-,21+,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50004169 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-vinyl-8-aza...) Show SMILES CN1C2CCC1[C@@H](C=C)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:11:9:1:4.3,0:1:6.9.10:4.3| Show InChI InChI=1S/C16H20ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h3-7,13-16H,1,8-10H2,2H3/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032534 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((E)-styryl...) Show SMILES CN1C2CCC1[C@@H](\C=C\c1ccccc1)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.15.16:4.3| Show InChI InChI=1S/C22H24ClN/c1-24-19-12-14-22(24)20(13-7-16-5-3-2-4-6-16)21(15-19)17-8-10-18(23)11-9-17/h2-11,13,19-22H,12,14-15H2,1H3/b13-7+/t19?,20-,21+,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032538 ((2S,3S)-2-Butyl-3-(4-chloro-phenyl)-8-methyl-8-aza...) Show SMILES CCCC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:19:18:10.4.9:6.7,THB:3:4:18:6.7| Show InChI InChI=1S/C18H26ClN/c1-3-4-5-16-17(13-6-8-14(19)9-7-13)12-15-10-11-18(16)20(15)2/h6-9,15-18H,3-5,10-12H2,1-2H3/t15?,16-,17+,18?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding constant for [3H]dopamine uptake was calculated from the Cheng-Prusoff relationship				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032536 ((2R,3S)-3-(4-Chloro-phenyl)-2-((Z)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C/Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8-/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032532 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-propyl-8-az...) Show SMILES CCC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:18:17:9.3.8:5.6,THB:2:3:17:5.6| Show InChI InChI=1S/C17H24ClN/c1-3-4-15-16(12-5-7-13(18)8-6-12)11-14-9-10-17(15)19(14)2/h5-8,14-17H,3-4,9-11H2,1-2H3/t14?,15-,16+,17?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032532 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-propyl-8-az...) Show SMILES CCC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:18:17:9.3.8:5.6,THB:2:3:17:5.6| Show InChI InChI=1S/C17H24ClN/c1-3-4-15-16(12-5-7-13(18)8-6-12)11-14-9-10-17(15)19(14)2/h5-8,14-17H,3-4,9-11H2,1-2H3/t14?,15-,16+,17?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032538 ((2S,3S)-2-Butyl-3-(4-chloro-phenyl)-8-methyl-8-aza...) Show SMILES CCCC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:19:18:10.4.9:6.7,THB:3:4:18:6.7| Show InChI InChI=1S/C18H26ClN/c1-3-4-5-16-17(13-6-8-14(19)9-7-13)12-15-10-11-18(16)20(15)2/h6-9,15-18H,3-5,10-12H2,1-2H3/t15?,16-,17+,18?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032535 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-phenethyl-8...) Show SMILES CN1C2CCC1[C@@H](CCc1ccccc1)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.15.16:4.3| Show InChI InChI=1S/C22H26ClN/c1-24-19-12-14-22(24)20(13-7-16-5-3-2-4-6-16)21(15-19)17-8-10-18(23)11-9-17/h2-6,8-11,19-22H,7,12-15H2,1H3/t19?,20-,21+,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032535 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-phenethyl-8...) Show SMILES CN1C2CCC1[C@@H](CCc1ccccc1)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,0:1:6.15.16:4.3| Show InChI InChI=1S/C22H26ClN/c1-24-19-12-14-22(24)20(13-7-16-5-3-2-4-6-16)21(15-19)17-8-10-18(23)11-9-17/h2-6,8-11,19-22H,7,12-15H2,1H3/t19?,20-,21+,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032537 ((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...) Show SMILES CCC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C |TLB:17:16:9.3.8:5.6,THB:2:3:16:5.6| Show InChI InChI=1S/C17H25N/c1-3-7-15-16(13-8-5-4-6-9-13)12-14-10-11-17(15)18(14)2/h4-6,8-9,14-17H,3,7,10-12H2,1-2H3/t14?,15-,16+,17?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032537 ((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...) Show SMILES CCC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C |TLB:17:16:9.3.8:5.6,THB:2:3:16:5.6| Show InChI InChI=1S/C17H25N/c1-3-7-15-16(13-8-5-4-6-9-13)12-14-10-11-17(15)18(14)2/h4-6,8-9,14-17H,3,7,10-12H2,1-2H3/t14?,15-,16+,17?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032533 ((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...) Show SMILES CC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:9:8:16:4.5,THB:1:2:16:4.5,17:16:8.2.7:4.5| Show InChI InChI=1S/C16H22ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h4-7,13-16H,3,8-10H2,1-2H3/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032533 ((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...) Show SMILES CC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:9:8:16:4.5,THB:1:2:16:4.5,17:16:8.2.7:4.5| Show InChI InChI=1S/C16H22ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h4-7,13-16H,3,8-10H2,1-2H3/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50004169 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-vinyl-8-aza...) Show SMILES CN1C2CCC1[C@@H](C=C)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:11:9:1:4.3,0:1:6.9.10:4.3| Show InChI InChI=1S/C16H20ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h3-7,13-16H,1,8-10H2,2H3/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50037521 ((2R,3S,8S)-3-Benzoyloxy-8-isocyanatosulfonyl-8-aza...) Show SMILES [H][C@@]12CCC(N1S(=O)(=O)N=C=O)[C@]([H])([C@H](C2)OC(=O)c1ccccc1)C(=O)OC |TLB:6:5:12.14.15:3.2,THB:16:14:5:3.2,25:12:5:3.2| Show InChI InChI=1S/C17H18N2O7S/c1-25-17(22)15-13-8-7-12(19(13)27(23,24)18-10-20)9-14(15)26-16(21)11-5-3-2-4-6-11/h2-6,12-15H,7-9H2,1H3/t12-,13?,14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032531 ((2S,3S)-3-(4-Chloro-phenyl)-2-hexyl-8-methyl-8-aza...) Show SMILES CCCCCC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:21:20:12.6.11:8.9,THB:5:6:20:8.9| Show InChI InChI=1S/C20H30ClN/c1-3-4-5-6-7-18-19(15-8-10-16(21)11-9-15)14-17-12-13-20(18)22(17)2/h8-11,17-20H,3-7,12-14H2,1-2H3/t17?,18-,19+,20?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50032531 ((2S,3S)-3-(4-Chloro-phenyl)-2-hexyl-8-methyl-8-aza...) Show SMILES CCCCCC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:21:20:12.6.11:8.9,THB:5:6:20:8.9| Show InChI InChI=1S/C20H30ClN/c1-3-4-5-6-7-18-19(15-8-10-16(21)11-9-15)14-17-12-13-20(18)22(17)2/h8-11,17-20H,3-7,12-14H2,1-2H3/t17?,18-,19+,20?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	271	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporter				J Med Chem 38: 3086-93 (1995) BindingDB Entry DOI: 10.7270/Q2KS6S69
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22418 (Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...) Show SMILES [H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c1ccccc1)C(=O)OC)N2C |TLB:18:6:22:3.2| Show InChI InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50037523 ((2R,3S,8S)-3-Benzoyloxy-8-trifluoromethanesulfonyl...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2S(=O)(=O)C(F)(F)F |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C17H18F3NO6S/c1-26-16(23)14-12-8-7-11(21(12)28(24,25)17(18,19)20)9-13(14)27-15(22)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3/t11?,12?,13-,14+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]-mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283380 (3-Benzoyloxy-8-carboxymethyl-8-aza-bicyclo[3.2.1]o...) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2CC(O)=O |THB:2:4:20:6.7| Show InChI InChI=1S/C18H21NO6/c1-24-18(23)16-13-8-7-12(19(13)10-15(20)21)9-14(16)25-17(22)11-5-3-2-4-6-11/h2-6,12-14,16H,7-10H2,1H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283377 (3-Benzoyloxy-8-methoxycarbonylmethyl-8-aza-bicyclo...) Show SMILES COC(=O)CN1C2CCC1C(C(C2)OC(=O)c1ccccc1)C(=O)OC |TLB:22:10:5:8.7| Show InChI InChI=1S/C19H23NO6/c1-24-16(21)11-20-13-8-9-14(20)17(19(23)25-2)15(10-13)26-18(22)12-6-4-3-5-7-12/h3-7,13-15,17H,8-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283376 (3-Benzoyloxy-8-(2-hydroxy-ethyl)-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2CCO |THB:2:4:20:6.7| Show InChI InChI=1S/C18H23NO5/c1-23-18(22)16-14-8-7-13(19(14)9-10-20)11-15(16)24-17(21)12-5-3-2-4-6-12/h2-6,13-16,20H,7-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50037519 ((2R,3S,8R)-3-Benzoyloxy-8-methanesulfonyl-8-aza-bi...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2S(C)(=O)=O |THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C17H21NO6S/c1-23-17(20)15-13-9-8-12(18(13)25(2,21)22)10-14(15)24-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12?,13?,14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50037518 ((2R,3S,8S)-3-Benzoyloxy-8-(4-nitro-benzenesulfonyl...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2S(=O)(=O)c1ccc(cc1)[N+]([O-])=O |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C22H22N2O8S/c1-31-22(26)20-18-12-9-16(13-19(20)32-21(25)14-5-3-2-4-6-14)23(18)33(29,30)17-10-7-15(8-11-17)24(27)28/h2-8,10-11,16,18-20H,9,12-13H2,1H3/t16?,18?,19-,20+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]-mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50037520 ((2R,3S,8S)-3-Benzoyloxy-8-(4-methoxy-benzenesulfon...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2S(=O)(=O)c1ccc(OC)cc1 |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C23H25NO7S/c1-29-17-9-11-18(12-10-17)32(27,28)24-16-8-13-19(24)21(23(26)30-2)20(14-16)31-22(25)15-6-4-3-5-7-15/h3-7,9-12,16,19-21H,8,13-14H2,1-2H3/t16?,19?,20-,21+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]-mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283381 (3-Benzoyloxy-8-nitro-8-aza-bicyclo[3.2.1]octane-2-...) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2[N+]([O-])=O |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C16H18N2O6/c1-23-16(20)14-12-8-7-11(17(12)18(21)22)9-13(14)24-15(19)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50037522 ((2R,3S,8S)-8-Benzenesulfonyl-3-benzoyloxy-8-aza-bi...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2S(=O)(=O)c1ccccc1 |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C22H23NO6S/c1-28-22(25)20-18-13-12-16(23(18)30(26,27)17-10-6-3-7-11-17)14-19(20)29-21(24)15-8-4-2-5-9-15/h2-11,16,18-20H,12-14H2,1H3/t16?,18?,19-,20+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.08E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trophix Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity was tested by measuring its ability to displace [3H]-mazindol binding against dopamine transporter (DAT) of rat striatal membranes				J Med Chem 37: 3440-2 (1994) BindingDB Entry DOI: 10.7270/Q2GB24PS
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283378 (Benzoic acid 5-oxo-6,7-diaza-tricyclo[5.3.0.0*4,8*...) Show SMILES O=C(OC1CC2CCC3C1C(=O)NN23)c1ccccc1 |TLB:7:8:12.10:3.5.4,THB:12:13:9.3.4:7.6,10:9:13:7.6,2:3:13:7.6| Show InChI InChI=1S/C15H16N2O3/c18-14-13-11-7-6-10(17(11)16-14)8-12(13)20-15(19)9-4-2-1-3-5-9/h1-5,10-13H,6-8H2,(H,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.49E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283375 (3-Benzoyloxy-8-nitroso-8-aza-bicyclo[3.2.1]octane-...) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2N=O |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C16H18N2O5/c1-22-16(20)14-12-8-7-11(18(12)17-21)9-13(14)23-15(19)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	9.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50283379 (8-Acetylamino-3-benzoyloxy-8-aza-bicyclo[3.2.1]oct...) Show SMILES COC(=O)C1C2CCC(CC1OC(=O)c1ccccc1)N2NC(C)=O |TLB:21:20:4.10.9:6.7,THB:11:10:20:6.7,2:4:20:6.7| Show InChI InChI=1S/C18H22N2O5/c1-11(21)19-20-13-8-9-14(20)16(18(23)24-2)15(10-13)25-17(22)12-6-4-3-5-7-12/h3-7,13-16H,8-10H2,1-2H3,(H,19,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to inhibit [3H]mazindol binding in rat corpus striatum P2 synaptosomes				Bioorg Med Chem Lett 4: 303-308 (1994) Article DOI: 10.1016/S0960-894X(01)80133-5 BindingDB Entry DOI: 10.7270/Q2F47PNG
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]dopamine uptake				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]mazindol from dopamine transporter				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]dopamine uptake				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004167 ((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...) Show SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:12:10:1:4.3,0:1:6.10.11:4.3| Show InChI InChI=1S/C16H19Cl2N/c1-19-13-6-7-16(19)14(8-9-17)15(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-16H,6-7,10H2,1H3/b9-8+/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]dopamine uptake				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50004169 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-vinyl-8-aza...) Show SMILES CN1C2CCC1[C@@H](C=C)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:11:9:1:4.3,0:1:6.9.10:4.3| Show InChI InChI=1S/C16H20ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h3-7,13-16H,1,8-10H2,2H3/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]-Mazindol from dopamine receptor				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50004169 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-vinyl-8-aza...) Show SMILES CN1C2CCC1[C@@H](C=C)[C@H](C2)c1ccc(Cl)cc1 |TLB:7:6:1:4.3,THB:11:9:1:4.3,0:1:6.9.10:4.3| Show InChI InChI=1S/C16H20ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h3-7,13-16H,1,8-10H2,2H3/t13?,14-,15+,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]mazindol from dopamine transporter				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50032533 ((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...) Show SMILES CC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:9:8:16:4.5,THB:1:2:16:4.5,17:16:8.2.7:4.5| Show InChI InChI=1S/C16H22ClN/c1-3-14-15(11-4-6-12(17)7-5-11)10-13-8-9-16(14)18(13)2/h4-7,13-16H,3,8-10H2,1-2H3/t13?,14-,15+,16?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]dopamine uptake				Bioorg Med Chem Lett 3: 1327-1332 (1993) Article DOI: 10.1016/S0960-894X(00)80341-8 BindingDB Entry DOI: 10.7270/Q2RJ4JZN
					More data for this Ligand-Target Pair

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