Compile Data Set for Download or QSAR

Found 173 hits with Last Name = 'bull' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine--tRNA ligase (Haemophilus influenzae (strain ATCC 51907 / DSM 11...)	BDBM50333116 (2-(3-((4-bromo-5-(1-fluorovinyl)-3-methylthiophen-...) Show SMILES Cc1c(Br)c(sc1CNCCCNc1cc(O)c2ccccc2n1)C(F)=C Show InChI InChI=1S/C20H21BrFN3OS/c1-12-17(27-20(13(2)22)19(12)21)11-23-8-5-9-24-18-10-16(26)14-6-3-4-7-15(14)25-18/h3-4,6-7,10,23H,2,5,8-9,11H2,1H3,(H2,24,25,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Replidyne, Inc Curated by ChEMBL					Assay Description Inhibition of Haemophilus influenzae MetRS				Antimicrob Agents Chemother 53: 86-94 (2008) Article DOI: 10.1128/AAC.00275-08 BindingDB Entry DOI: 10.7270/Q2MP53JD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93073 (ACS No 172) Show SMILES [O-]C(=O)c1ccccc1Nc1ccccc1C([O-])=O Show InChI InChI=1S/C14H11NO4/c16-13(17)9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)14(18)19/h1-8,15H,(H,16,17)(H,18,19)/p-2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93074 (ACS No 142) Show SMILES Cc1cc(C)c(N)c(c1)C([O-])=O Show InChI InChI=1S/C9H11NO2/c1-5-3-6(2)8(10)7(4-5)9(11)12/h3-4H,10H2,1-2H3,(H,11,12)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Salicylate synthase (Mycobacterium tuberculosis)	BDBM92747 (cyclopropyl-AMT) Show SMILES Oc1c(OC(=CC2CC2)C([O-])=O)cccc1C([O-])=O |w:5.5| Show InChI InChI=1S/C13H12O6/c14-11-8(12(15)16)2-1-3-9(11)19-10(13(17)18)6-7-4-5-7/h1-3,6-7,14H,4-5H2,(H,15,16)(H,17,18)/p-2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Auckland					Assay Description The thermal stability of MbtI in the absence and presence of inhibitors was measured using a fluorescence-based thermal shift assay.				Biochemistry 51: 4868-79 (2012) Article DOI: 10.1021/bi3002067 BindingDB Entry DOI: 10.7270/Q28K77PG
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93075 (ACS No 145) Show SMILES COc1cc(N)c(cc1OC)C([O-])=O Show InChI InChI=1S/C9H11NO4/c1-13-7-3-5(9(11)12)6(10)4-8(7)14-2/h3-4H,10H2,1-2H3,(H,11,12)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93076 (ACS No 174) Show SMILES [O-]C(=O)c1ccccc1Cc1ccccc1 Show InChI InChI=1S/C14H12O2/c15-14(16)13-9-5-4-8-12(13)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,15,16)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93077 (ACS No 179) Show SMILES COc1cccc2c1cc([N+]([O-])=O)c1c(cc3OCOc3c21)C([O-])=O Show InChI InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93078 (ACS No 126) Show SMILES COc1ccc(cc1N)C([O-])=O Show InChI InChI=1S/C8H9NO3/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4H,9H2,1H3,(H,10,11)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93079 (ACS No 165) Show SMILES NC(CCCNc1ccc(cc1N(=O)=O)[N+]([O-])=O)CC([O-])=O Show InChI InChI=1S/C12H16N4O6/c13-8(6-12(17)18)2-1-5-14-10-4-3-9(15(19)20)7-11(10)16(21)22/h3-4,7-8,14H,1-2,5-6,13H2,(H,17,18)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM85513 (ACS No 10 | CAS_54-21-7 | NSC_5900 | Sodium salicy...) Show SMILES Oc1ccccc1C([O-])=O Show InChI InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401890 (CHEMBL2206606) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(C)C23CC4CC(CC(C4)C2)C3)cc1 |r,TLB:28:31:34:38.37.36,THB:32:33:36:40.31.39,32:31:34.33.38:36,39:31:34:38.37.36,39:37:34:40.32.31| Show InChI InChI=1S/C34H46N4O5/c1-22(2)43-32(41)27-7-9-28(10-8-27)36-33(42)37-30(18-23-5-11-29(39)12-6-23)31(40)35-13-14-38(3,4)34-19-24-15-25(20-34)17-26(16-24)21-34/h5-12,22,24-26,30H,13-21H2,1-4H3,(H3-,35,36,37,39,40,41,42)/p+1/t24?,25?,26?,30-,34?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401881 (CHEMBL2206587) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](C)(Cc3ccc4OCOc4c3)CC2)cc1 |r| Show InChI InChI=1S/C33H38N4O7/c1-22(2)44-32(40)25-7-9-26(10-8-25)34-33(41)35-28(18-23-4-11-27(38)12-5-23)31(39)36-14-16-37(3,17-15-36)20-24-6-13-29-30(19-24)43-21-42-29/h4-13,19,22,28H,14-18,20-21H2,1-3H3,(H2-,34,35,38,40,41)/p+1/t28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401890 (CHEMBL2206606) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(C)C23CC4CC(CC(C4)C2)C3)cc1 |r,TLB:28:31:34:38.37.36,THB:32:33:36:40.31.39,32:31:34.33.38:36,39:31:34:38.37.36,39:37:34:40.32.31| Show InChI InChI=1S/C34H46N4O5/c1-22(2)43-32(41)27-7-9-28(10-8-27)36-33(42)37-30(18-23-5-11-29(39)12-6-23)31(40)35-13-14-38(3,4)34-19-24-15-25(20-34)17-26(16-24)21-34/h5-12,22,24-26,30H,13-21H2,1-4H3,(H3-,35,36,37,39,40,41,42)/p+1/t24?,25?,26?,30-,34?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50401890 (CHEMBL2206606) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(C)C23CC4CC(CC(C4)C2)C3)cc1 |r,TLB:28:31:34:38.37.36,THB:32:33:36:40.31.39,32:31:34.33.38:36,39:31:34:38.37.36,39:37:34:40.32.31| Show InChI InChI=1S/C34H46N4O5/c1-22(2)43-32(41)27-7-9-28(10-8-27)36-33(42)37-30(18-23-5-11-29(39)12-6-23)31(40)35-13-14-38(3,4)34-19-24-15-25(20-34)17-26(16-24)21-34/h5-12,22,24-26,30H,13-21H2,1-4H3,(H3-,35,36,37,39,40,41,42)/p+1/t24?,25?,26?,30-,34?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401898 (CHEMBL2207177) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H](C2)[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-23(2)44-33(42)26-11-15-28(16-12-26)36-34(43)37-31(20-24-9-17-30(40)18-10-24)32(41)38-19-5-6-29(21-38)39(3,4)22-25-7-13-27(35)14-8-25/h7-18,23,29,31H,5-6,19-22H2,1-4H3,(H2-,36,37,40,42,43)/p+1/t29-,31+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401891 (CHEMBL2206605) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(Cc2ccc3ccccc3c2)Cc2ccc3ccccc3c2)cc1 |r| Show InChI InChI=1S/C45H46N4O5/c1-31(2)54-44(52)37-18-20-40(21-19-37)47-45(53)48-42(28-32-14-22-41(50)23-15-32)43(51)46-24-25-49(3,29-33-12-16-35-8-4-6-10-38(35)26-33)30-34-13-17-36-9-5-7-11-39(36)27-34/h4-23,26-27,31,42H,24-25,28-30H2,1-3H3,(H3-,46,47,48,50,51,52,53)/p+1/t42-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401879 (CHEMBL2206589) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](Cc3ccc(Cl)cc3)(CC2)C(C)C)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-23(2)39(22-26-5-11-28(35)12-6-26)19-17-38(18-20-39)32(41)31(21-25-7-15-30(40)16-8-25)37-34(43)36-29-13-9-27(10-14-29)33(42)44-24(3)4/h5-16,23-24,31H,17-22H2,1-4H3,(H2-,36,37,40,42,43)/p+1/t31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401888 (CHEMBL2206608) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(Cc3ccc(Cl)cc3)CCCCC2)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-24(2)44-33(42)27-10-14-29(15-11-27)37-34(43)38-31(22-25-8-16-30(40)17-9-25)32(41)36-18-21-39(19-4-3-5-20-39)23-26-6-12-28(35)13-7-26/h6-17,24,31H,3-5,18-23H2,1-2H3,(H3-,36,37,38,40,41,42,43)/p+1/t31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401877 (CHEMBL2206591) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](CC3CCc4ccccc4C3)(Cc3ccc(Cl)cc3)CC2)cc1 |r| Show InChI InChI=1S/C42H47ClN4O5/c1-29(2)52-41(50)34-13-17-37(18-14-34)44-42(51)45-39(26-30-10-19-38(48)20-11-30)40(49)46-21-23-47(24-22-46,27-31-8-15-36(43)16-9-31)28-32-7-12-33-5-3-4-6-35(33)25-32/h3-6,8-11,13-20,29,32,39H,7,12,21-28H2,1-2H3,(H2-,44,45,48,50,51)/p+1/t32?,39-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41.2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401889 (CHEMBL2206607) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(Cc3ccc(Cl)cc3)CCCC2)cc1 |r| Show InChI InChI=1S/C33H39ClN4O5/c1-23(2)43-32(41)26-9-13-28(14-10-26)36-33(42)37-30(21-24-7-15-29(39)16-8-24)31(40)35-17-20-38(18-3-4-19-38)22-25-5-11-27(34)12-6-25/h5-16,23,30H,3-4,17-22H2,1-2H3,(H3-,35,36,37,39,40,41,42)/p+1/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401897 (CHEMBL2206599) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@@H](C2)[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-23(2)44-33(42)26-11-15-28(16-12-26)36-34(43)37-31(20-24-9-17-30(40)18-10-24)32(41)38-19-5-6-29(21-38)39(3,4)22-25-7-13-27(35)14-8-25/h7-18,23,29,31H,5-6,19-22H2,1-4H3,(H2-,36,37,40,42,43)/p+1/t29-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45.3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401880 (CHEMBL2206588) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](C)(CC3CCCCC3)CC2)cc1 |r| Show InChI InChI=1S/C32H44N4O5/c1-23(2)41-31(39)26-11-13-27(14-12-26)33-32(40)34-29(21-24-9-15-28(37)16-10-24)30(38)35-17-19-36(3,20-18-35)22-25-7-5-4-6-8-25/h9-16,23,25,29H,4-8,17-22H2,1-3H3,(H2-,33,34,37,39,40)/p+1/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401873 (CHEMBL2206595) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCc2n(Cc3ccc(Cl)cc3)cc[n+]2Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C38H37Cl2N5O5/c1-25(2)50-37(48)29-9-15-32(16-10-29)42-38(49)43-34(21-26-7-17-33(46)18-8-26)36(47)41-22-35-44(23-27-3-11-30(39)12-4-27)19-20-45(35)24-28-5-13-31(40)14-6-28/h3-20,25,34H,21-24H2,1-2H3,(H3-,41,42,43,46,47,48,49)/p+1/t34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401878 (CHEMBL2206590) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](CC3CCCCC3)(Cc3ccc(Cl)cc3)CC2)cc1 |r| Show InChI InChI=1S/C38H47ClN4O5/c1-27(2)48-37(46)31-12-16-33(17-13-31)40-38(47)41-35(24-28-10-18-34(44)19-11-28)36(45)42-20-22-43(23-21-42,25-29-6-4-3-5-7-29)26-30-8-14-32(39)15-9-30/h8-19,27,29,35H,3-7,20-26H2,1-2H3,(H2-,40,41,44,46,47)/p+1/t35-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401896 (CHEMBL2206600) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC(CC2)[N+]2(Cc3ccc(Cl)cc3)CCCC2)cc1 |r| Show InChI InChI=1S/C36H43ClN4O5/c1-25(2)46-35(44)28-9-13-30(14-10-28)38-36(45)39-33(23-26-7-15-32(42)16-8-26)34(43)40-19-17-31(18-20-40)41(21-3-4-22-41)24-27-5-11-29(37)12-6-27/h5-16,25,31,33H,3-4,17-24H2,1-2H3,(H2-,38,39,42,44,45)/p+1/t33-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401894 (CHEMBL2206602) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(Cc2ccc(Cl)cc2)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C37H40Cl2N4O5/c1-25(2)48-36(46)29-10-16-32(17-11-29)41-37(47)42-34(22-26-8-18-33(44)19-9-26)35(45)40-20-21-43(3,23-27-4-12-30(38)13-5-27)24-28-6-14-31(39)15-7-28/h4-19,25,34H,20-24H2,1-3H3,(H3-,40,41,42,44,45,46,47)/p+1/t34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401891 (CHEMBL2206605) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(Cc2ccc3ccccc3c2)Cc2ccc3ccccc3c2)cc1 |r| Show InChI InChI=1S/C45H46N4O5/c1-31(2)54-44(52)37-18-20-40(21-19-37)47-45(53)48-42(28-32-14-22-41(50)23-15-32)43(51)46-24-25-49(3,29-33-12-16-35-8-4-6-10-38(35)26-33)30-34-13-17-36-9-5-7-11-39(36)27-34/h4-23,26-27,31,42H,24-25,28-30H2,1-3H3,(H3-,46,47,48,50,51,52,53)/p+1/t42-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82.2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401888 (CHEMBL2206608) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(Cc3ccc(Cl)cc3)CCCCC2)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-24(2)44-33(42)27-10-14-29(15-11-27)37-34(43)38-31(22-25-8-16-30(40)17-9-25)32(41)36-18-21-39(19-4-3-5-20-39)23-26-6-12-28(35)13-7-26/h6-17,24,31H,3-5,18-23H2,1-2H3,(H3-,36,37,38,40,41,42,43)/p+1/t31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401882 (CHEMBL2206586) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC(C)(C)C[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C34H43ClN4O5/c1-23(2)44-32(42)26-11-15-28(16-12-26)37-33(43)38-30(19-24-9-17-29(40)18-10-24)31(41)36-21-34(3,4)22-39(5,6)20-25-7-13-27(35)14-8-25/h7-18,23,30H,19-22H2,1-6H3,(H3-,36,37,38,40,41,42,43)/p+1/t30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401896 (CHEMBL2206600) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC(CC2)[N+]2(Cc3ccc(Cl)cc3)CCCC2)cc1 |r| Show InChI InChI=1S/C36H43ClN4O5/c1-25(2)46-35(44)28-9-13-30(14-10-28)38-36(45)39-33(23-26-7-15-32(42)16-8-26)34(43)40-19-17-31(18-20-40)41(21-3-4-22-41)24-27-5-11-29(37)12-6-27/h5-16,25,31,33H,3-4,17-24H2,1-2H3,(H2-,38,39,42,44,45)/p+1/t33-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401879 (CHEMBL2206589) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](Cc3ccc(Cl)cc3)(CC2)C(C)C)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-23(2)39(22-26-5-11-28(35)12-6-26)19-17-38(18-20-39)32(41)31(21-25-7-15-30(40)16-8-25)37-34(43)36-29-13-9-27(10-14-29)33(42)44-24(3)4/h5-16,23-24,31H,17-22H2,1-4H3,(H2-,36,37,40,42,43)/p+1/t31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	97.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401897 (CHEMBL2206599) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@@H](C2)[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-23(2)44-33(42)26-11-15-28(16-12-26)36-34(43)37-31(20-24-9-17-30(40)18-10-24)32(41)38-19-5-6-29(21-38)39(3,4)22-25-7-13-27(35)14-8-25/h7-18,23,29,31H,5-6,19-22H2,1-4H3,(H2-,36,37,40,42,43)/p+1/t29-,31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401889 (CHEMBL2206607) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(Cc3ccc(Cl)cc3)CCCC2)cc1 |r| Show InChI InChI=1S/C33H39ClN4O5/c1-23(2)43-32(41)26-9-13-28(14-10-26)36-33(42)37-30(21-24-7-15-29(39)16-8-24)31(40)35-17-20-38(18-3-4-19-38)22-25-5-11-27(34)12-6-25/h5-16,23,30H,3-4,17-22H2,1-2H3,(H3-,35,36,37,39,40,41,42)/p+1/t30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50401878 (CHEMBL2206590) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](CC3CCCCC3)(Cc3ccc(Cl)cc3)CC2)cc1 |r| Show InChI InChI=1S/C38H47ClN4O5/c1-27(2)48-37(46)31-12-16-33(17-13-31)40-38(47)41-35(24-28-10-18-34(44)19-11-28)36(45)42-20-22-43(23-21-42,25-29-6-4-3-5-7-29)26-30-8-14-32(39)15-9-30/h8-19,27,29,35H,3-7,20-26H2,1-2H3,(H2-,40,41,44,46,47)/p+1/t35-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401893 (CHEMBL2206603) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C31H37ClN4O5/c1-21(2)41-30(39)24-9-13-26(14-10-24)34-31(40)35-28(19-22-7-15-27(37)16-8-22)29(38)33-17-18-36(3,4)20-23-5-11-25(32)12-6-23/h5-16,21,28H,17-20H2,1-4H3,(H3-,33,34,35,37,38,39,40)/p+1/t28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401887 (CHEMBL2206609) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(C)CCCCCC2)cc1 |r| Show InChI InChI=1S/C29H40N4O5/c1-21(2)38-28(36)23-10-12-24(13-11-23)31-29(37)32-26(20-22-8-14-25(34)15-9-22)27(35)30-16-19-33(3)17-6-4-5-7-18-33/h8-15,21,26H,4-7,16-20H2,1-3H3,(H3-,30,31,32,34,35,36,37)/p+1/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401883 (CHEMBL2206585) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCCC[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C32H39ClN4O5/c1-22(2)42-31(40)25-10-14-27(15-11-25)35-32(41)36-29(20-23-8-16-28(38)17-9-23)30(39)34-18-5-19-37(3,4)21-24-6-12-26(33)13-7-24/h6-17,22,29H,5,18-21H2,1-4H3,(H3-,34,35,36,38,39,40,41)/p+1/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401873 (CHEMBL2206595) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCc2n(Cc3ccc(Cl)cc3)cc[n+]2Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C38H37Cl2N5O5/c1-25(2)50-37(48)29-9-15-32(16-10-29)42-38(49)43-34(21-26-7-17-33(46)18-8-26)36(47)41-22-35-44(23-27-3-11-30(39)12-4-27)19-20-45(35)24-28-5-13-31(40)14-6-28/h3-20,25,34H,21-24H2,1-2H3,(H3-,41,42,43,46,47,48,49)/p+1/t34-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401880 (CHEMBL2206588) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CC[N+](C)(CC3CCCCC3)CC2)cc1 |r| Show InChI InChI=1S/C32H44N4O5/c1-23(2)41-31(39)26-11-13-27(14-12-26)33-32(40)34-29(21-24-9-15-28(37)16-10-24)30(38)35-17-19-36(3,20-18-35)22-25-7-5-4-6-8-25/h9-16,23,25,29H,4-8,17-22H2,1-3H3,(H2-,33,34,37,39,40)/p+1/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401883 (CHEMBL2206585) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCCC[N+](C)(C)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C32H39ClN4O5/c1-22(2)42-31(40)25-10-14-27(15-11-25)35-32(41)36-29(20-23-8-16-28(38)17-9-23)30(39)34-18-5-19-37(3,4)21-24-6-12-26(33)13-7-24/h6-17,22,29H,5,18-21H2,1-4H3,(H3-,34,35,36,38,39,40,41)/p+1/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50401888 (CHEMBL2206608) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(Cc3ccc(Cl)cc3)CCCCC2)cc1 |r| Show InChI InChI=1S/C34H41ClN4O5/c1-24(2)44-33(42)27-10-14-29(15-11-27)37-34(43)38-31(22-25-8-16-30(40)17-9-25)32(41)36-18-21-39(19-4-3-5-20-39)23-26-6-12-28(35)13-7-26/h6-17,24,31H,3-5,18-23H2,1-2H3,(H3-,36,37,38,40,41,42,43)/p+1/t31-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401892 (CHEMBL2206604) Show SMILES CC[N+](CC)(CCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Nc1ccc(cc1)C(=O)OC(C)C)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C33H41ClN4O5/c1-5-38(6-2,22-25-7-13-27(34)14-8-25)20-19-35-31(40)30(21-24-9-17-29(39)18-10-24)37-33(42)36-28-15-11-26(12-16-28)32(41)43-23(3)4/h7-18,23,30H,5-6,19-22H2,1-4H3,(H3-,35,36,37,39,40,41,42)/p+1/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401886 (CHEMBL2206610) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(C(C)C)C(C)C)cc1 |r| Show InChI InChI=1S/C29H42N4O5/c1-19(2)33(7,20(3)4)17-16-30-27(35)26(18-22-8-14-25(34)15-9-22)32-29(37)31-24-12-10-23(11-13-24)28(36)38-21(5)6/h8-15,19-21,26H,16-18H2,1-7H3,(H3-,30,31,32,34,35,36,37)/p+1/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401892 (CHEMBL2206604) Show SMILES CC[N+](CC)(CCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Nc1ccc(cc1)C(=O)OC(C)C)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C33H41ClN4O5/c1-5-38(6-2,22-25-7-13-27(34)14-8-25)20-19-35-31(40)30(21-24-9-17-29(39)18-10-24)37-33(42)36-28-15-11-26(12-16-28)32(41)43-23(3)4/h7-18,23,30H,5-6,19-22H2,1-4H3,(H3-,35,36,37,39,40,41,42)/p+1/t30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	311	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50401873 (CHEMBL2206595) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCc2n(Cc3ccc(Cl)cc3)cc[n+]2Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C38H37Cl2N5O5/c1-25(2)50-37(48)29-9-15-32(16-10-29)42-38(49)43-34(21-26-7-17-33(46)18-8-26)36(47)41-22-35-44(23-27-3-11-30(39)12-4-27)19-20-45(35)24-28-5-13-31(40)14-6-28/h3-20,25,34H,21-24H2,1-2H3,(H3-,41,42,43,46,47,48,49)/p+1/t34-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401887 (CHEMBL2206609) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+]2(C)CCCCCC2)cc1 |r| Show InChI InChI=1S/C29H40N4O5/c1-21(2)38-28(36)23-10-12-24(13-11-23)31-29(37)32-26(20-22-8-14-25(34)15-9-22)27(35)30-16-19-33(3)17-6-4-5-7-18-33/h8-15,21,26H,4-7,16-20H2,1-3H3,(H3-,30,31,32,34,35,36,37)/p+1/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50401886 (CHEMBL2206610) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(C(C)C)C(C)C)cc1 |r| Show InChI InChI=1S/C29H42N4O5/c1-19(2)33(7,20(3)4)17-16-30-27(35)26(18-22-8-14-25(34)15-9-22)32-29(37)31-24-12-10-23(11-13-24)28(36)38-21(5)6/h8-15,19-21,26H,16-18H2,1-7H3,(H3-,30,31,32,34,35,36,37)/p+1/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	337	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50401894 (CHEMBL2206602) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NCC[N+](C)(Cc2ccc(Cl)cc2)Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C37H40Cl2N4O5/c1-25(2)48-36(46)29-10-16-32(17-11-29)41-37(47)42-34(22-26-8-18-33(44)19-9-26)35(45)40-20-21-43(3,23-27-4-12-30(38)13-5-27)24-28-6-14-31(39)15-7-28/h4-19,25,34H,20-24H2,1-3H3,(H3-,40,41,42,44,45,46,47)/p+1/t34-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	379	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50401874 (CHEMBL2206594) Show SMILES CC(C)OC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N(C)Cc2n(C)cc[n+]2Cc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C33H36ClN5O5/c1-22(2)44-32(42)25-9-13-27(14-10-25)35-33(43)36-29(19-23-7-15-28(40)16-8-23)31(41)38(4)21-30-37(3)17-18-39(30)20-24-5-11-26(34)12-6-24/h5-18,22,29H,19-21H2,1-4H3,(H2-,35,36,40,42,43)/p+1/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FL...				Bioorg Med Chem Lett 22: 7087-91 (2012) Article DOI: 10.1016/j.bmcl.2012.09.085 BindingDB Entry DOI: 10.7270/Q2ZK5HT1
					More data for this Ligand-Target Pair
Perforin-1 (Homo sapiens (Human))	BDBM50445263 (CHEMBL3103651) Show SMILES O=C1NC(=O)\C(N1)=C/c1ccc(s1)-c1ccc2C(=O)NCc2c1 Show InChI InChI=1S/C16H11N3O3S/c20-14-11-3-1-8(5-9(11)7-17-14)13-4-2-10(23-13)6-12-15(21)19-16(22)18-12/h1-6H,7H2,(H,17,20)(H2,18,19,21,22)/b12-6+	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...				J Med Chem 56: 9542-55 (2014) Article DOI: 10.1021/jm401604x BindingDB Entry DOI: 10.7270/Q26Q1ZQ3
					More data for this Ligand-Target Pair

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