Compile Data Set for Download or QSAR

Found 169 hits with Last Name = 'chen' and Initial = 'wl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM200712 (US9233086, 10A) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C35H51N7O4/c1-5-34(6-2,41-29(43)24(3)4)31(45)39-27(20-15-23-38-33(36)37)30(44)42-35(21-13-14-22-35)32(46)40-28(25-16-9-7-10-17-25)26-18-11-8-12-19-26/h7-12,16-19,24,27-28H,5-6,13-15,20-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,43)(H,42,44)(H4,36,37,38)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM200722 (US9233086, 10K) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C35H49Cl2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM200723 (US9233086, 10L) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H49F2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCN(C)C)N1CCCN(C)CC1 Show InChI InChI=1S/C26H43N7O2/c1-30(2)10-7-17-35-24-19-22-21(18-23(24)34-5)25(27-20-8-13-32(4)14-9-20)29-26(28-22)33-12-6-11-31(3)15-16-33/h18-20H,6-17H2,1-5H3,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin) using histone H3 (1 to 25 residues) as substrate preincubated for 2 mins followed by substrate addition measured f...				Bioorg Med Chem 24: 6102-6108 (2016) Article DOI: 10.1016/j.bmc.2016.09.071 BindingDB Entry DOI: 10.7270/Q29C70D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50353128 (CHEMBL1231795) Show SMILES COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN1CCCC1)C1CCCCC1 Show InChI InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Competitive inhibition of G9a (unknown origin) by Morrison plot analysis in presence of histone H3 (1 to 25 residues)				Bioorg Med Chem 24: 6102-6108 (2016) Article DOI: 10.1016/j.bmc.2016.09.071 BindingDB Entry DOI: 10.7270/Q29C70D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Menin (Homo sapiens (Human))	BDBM50454123 (CHEMBL4216333) Show SMILES NCC(CCN1CCC(=CC1)c1ccc(Cl)cc1)(C1CCCC1)c1ccccc1 |c:8| Show InChI InChI=1S/C26H33ClN2/c27-25-12-10-21(11-13-25)22-14-17-29(18-15-22)19-16-26(20-28,24-8-4-5-9-24)23-6-2-1-3-7-23/h1-3,6-7,10-14,24H,4-5,8-9,15-20,28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of FITC-MBM1 from full length human menin measured after 2 hrs by fluorescence polarization assay				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164787 (CHEMBL3798088) Show SMILES CC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@](C)(CCCCNC(=O)[C@H](NC1=O)c1ccccc1)NC(=O)C(C)C |r| Show InChI InChI=1S/C29H46N8O5/c1-5-20-24(39)36-22(19-12-7-6-8-13-19)26(41)32-16-10-9-15-29(4,37-23(38)18(2)3)27(42)35-21(25(40)34-20)14-11-17-33-28(30)31/h6-8,12-13,18,20-22H,5,9-11,14-17H2,1-4H3,(H,32,41)(H,34,40)(H,35,42)(H,36,39)(H,37,38)(H4,30,31,33)/t20-,21-,22+,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of fluorescence-labeled Ac-ARA peptide binding to WDR5 (unknown origin) by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50454121 (CHEMBL4211366) Show SMILES [H][C@@]12CN(CC(O)CCCc3ccccc3)C[C@@]([H])(C1)n1c(C2)cccc1=O |THB:26:20:2.3.16:19,4:3:19:20.21.22| Show InChI InChI=1S/C22H28N2O2/c25-21(10-4-8-17-6-2-1-3-7-17)16-23-14-18-12-19-9-5-11-22(26)24(19)20(13-18)15-23/h1-3,5-7,9,11,18,20-21,25H,4,8,10,12-16H2/t18-,20+,21?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assay				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM200723 (US9233086, 10L) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H49F2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM200723 (US9233086, 10L) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H49F2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM200723 (US9233086, 10L) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H49F2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-WIN peptide binding to N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) expressed in Rosetta2-(DE3) pL...				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM200723 (US9233086, 10L) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H49F2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of fluorescence-labeled Ac-ARA peptide binding to WDR5 (unknown origin) by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50442103 (CHEMBL2441082) Show SMILES COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN1CCCC1)N1CCC(F)(F)CC1 Show InChI InChI=1S/C29H44F2N6O2/c1-21(2)36-14-7-22(8-15-36)32-27-23-19-25(38-3)26(39-18-6-13-35-11-4-5-12-35)20-24(23)33-28(34-27)37-16-9-29(30,31)10-17-37/h19-22H,4-18H2,1-3H3,(H,32,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<2.5	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin)				Bioorg Med Chem 24: 6102-6108 (2016) Article DOI: 10.1016/j.bmc.2016.09.071 BindingDB Entry DOI: 10.7270/Q29C70D7
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM200712 (US9233086, 10A) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C35H51N7O4/c1-5-34(6-2,41-29(43)24(3)4)31(45)39-27(20-15-23-38-33(36)37)30(44)42-35(21-13-14-22-35)32(46)40-28(25-16-9-7-10-17-25)26-18-11-8-12-19-26/h7-12,16-19,24,27-28H,5-6,13-15,20-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,43)(H,42,44)(H4,36,37,38)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50446376 (CHEMBL3109630) Show SMILES COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1 |t:19| Show InChI InChI=1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin)				Bioorg Med Chem 24: 6102-6108 (2016) Article DOI: 10.1016/j.bmc.2016.09.071 BindingDB Entry DOI: 10.7270/Q29C70D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM200722 (US9233086, 10K) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C35H49Cl2N7O4/c1-5-34(6-2,43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18,22,27-28H,5-10,19-21H2,1-4H3,(H,41,47)(H,42,48)(H,43,45)(H,44,46)(H4,38,39,40)/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208354 (CHEMBL3884329) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)CCCN)cc1 Show InChI InChI=1S/C29H34ClFN6O2/c1-18-27(30)22(17-23(33)28(18)31)29(39)35-24-16-20(7-10-25(24)37-14-12-36(2)13-15-37)19-5-8-21(9-6-19)34-26(38)4-3-11-32/h5-10,16-17H,3-4,11-15,32-33H2,1-2H3,(H,34,38)(H,35,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208353 (CHEMBL3884726) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)C2CCNCC2)cc1 Show InChI InChI=1S/C31H36ClFN6O2/c1-19-28(32)24(18-25(34)29(19)33)31(41)37-26-17-22(5-8-27(26)39-15-13-38(2)14-16-39)20-3-6-23(7-4-20)36-30(40)21-9-11-35-12-10-21/h3-8,17-18,21,35H,9-16,34H2,1-2H3,(H,36,40)(H,37,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50454124 (CHEMBL3780822) Show SMILES Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(Cc3cn[nH]c3)c(cc12)C#N Show InChI InChI=1S/C28H27F3N8S/c1-17-19(2-3-25-23(17)8-21(11-32)39(25)14-18-12-35-36-13-18)15-38-6-4-20(5-7-38)37-26-24-9-22(10-28(29,30)31)40-27(24)34-16-33-26/h2-3,8-9,12-13,16,20H,4-7,10,14-15H2,1H3,(H,35,36)(H,33,34,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of FITC-MBM1 from full length human menin measured after 1 hr by fluorescence polarization assay				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50300041 (7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...) Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCN(C)C)N1CCCN(C)CC1 Show InChI InChI=1S/C26H43N7O2/c1-30(2)10-7-17-35-24-19-22-21(18-23(24)34-5)25(27-20-8-13-32(4)14-9-20)29-26(28-22)33-12-6-11-31(3)15-16-33/h18-20H,6-17H2,1-5H3,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin) using histone H3 (1 to 25 residues) as substrate preincubated for 2 mins followed by substrate addition measured f...				Bioorg Med Chem 24: 6102-6108 (2016) Article DOI: 10.1016/j.bmc.2016.09.071 BindingDB Entry DOI: 10.7270/Q29C70D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50353128 (CHEMBL1231795) Show SMILES COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN1CCCC1)C1CCCCC1 Show InChI InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	<15	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin) using histone H3 (1 to 25 residues) as substrate preincubated for 2 mins followed by substrate addition measured f...				Bioorg Med Chem 24: 6102-6108 (2016) Article DOI: 10.1016/j.bmc.2016.09.071 BindingDB Entry DOI: 10.7270/Q29C70D7
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208355 (CHEMBL3885099) Show SMILES CC(N)C(=O)Nc1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 Show InChI InChI=1S/C28H32ClFN6O2/c1-16-25(29)21(15-22(32)26(16)30)28(38)34-23-14-19(6-9-24(23)36-12-10-35(3)11-13-36)18-4-7-20(8-5-18)33-27(37)17(2)31/h4-9,14-15,17H,10-13,31-32H2,1-3H3,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208369 (CHEMBL3884291) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccncc1 Show InChI InChI=1S/C24H25ClFN5O/c1-15-22(25)18(14-19(27)23(15)26)24(32)29-20-13-17(16-5-7-28-8-6-16)3-4-21(20)31-11-9-30(2)10-12-31/h3-8,13-14H,9-12,27H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195454 (CHEMBL3893446) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(c(F)c(C)c1Cl)[N+]([O-])=O)C(=O)OC1CCCCC1 Show InChI InChI=1S/C26H30ClFN4O5/c1-16-23(27)19(15-22(24(16)28)32(35)36)25(33)29-20-14-17(26(34)37-18-6-4-3-5-7-18)8-9-21(20)31-12-10-30(2)11-13-31/h8-9,14-15,18H,3-7,10-13H2,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195365 (CHEMBL3943757) Show SMILES CC(C)OC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(N)c2)c1 Show InChI InChI=1S/C22H27FN4O3/c1-14(2)30-22(29)16-5-7-20(27-10-8-26(3)9-11-27)19(13-16)25-21(28)15-4-6-17(23)18(24)12-15/h4-7,12-14H,8-11,24H2,1-3H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195366 (CHEMBL3906985) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(N)c1)C(=O)Oc1ccccc1 Show InChI InChI=1S/C25H25FN4O3/c1-29-11-13-30(14-12-29)23-10-8-18(25(32)33-19-5-3-2-4-6-19)16-22(23)28-24(31)17-7-9-20(26)21(27)15-17/h2-10,15-16H,11-14,27H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195368 (CHEMBL3953704) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)C(=O)OC1CCCCC1 Show InChI InChI=1S/C26H31ClFN3O3/c1-17-21(28)10-9-20(24(17)27)25(32)29-22-16-18(26(33)34-19-6-4-3-5-7-19)8-11-23(22)31-14-12-30(2)13-15-31/h8-11,16,19H,3-7,12-15H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195452 (CHEMBL3929919) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(c1)[N+]([O-])=O)C(=O)OC1CCCCC1 Show InChI InChI=1S/C25H29FN4O5/c1-28-11-13-29(14-12-28)22-10-8-18(25(32)35-19-5-3-2-4-6-19)15-21(22)27-24(31)17-7-9-20(26)23(16-17)30(33)34/h7-10,15-16,19H,2-6,11-14H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195431 (CHEMBL3965924) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C19H19FN4O5/c1-22-6-8-23(9-7-22)16-5-3-13(19(26)27)10-15(16)21-18(25)12-2-4-14(20)17(11-12)24(28)29/h2-5,10-11H,6-9H2,1H3,(H,21,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195429 (CHEMBL3956505) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(N)c1)C(=O)OC1CCCCC1 Show InChI InChI=1S/C25H31FN4O3/c1-29-11-13-30(14-12-29)23-10-8-18(25(32)33-19-5-3-2-4-6-19)16-22(23)28-24(31)17-7-9-20(26)21(27)15-17/h7-10,15-16,19H,2-6,11-14,27H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195428 (CHEMBL3938878) Show SMILES COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(N)c2)c1 Show InChI InChI=1S/C20H23FN4O3/c1-24-7-9-25(10-8-24)18-6-4-14(20(27)28-2)12-17(18)23-19(26)13-3-5-15(21)16(22)11-13/h3-6,11-12H,7-10,22H2,1-2H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195370 (CHEMBL3936042) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)C(O)=O Show InChI InChI=1S/C20H21ClFN3O3/c1-12-15(22)5-4-14(18(12)21)19(26)23-16-11-13(20(27)28)3-6-17(16)25-9-7-24(2)8-10-25/h3-6,11H,7-10H2,1-2H3,(H,23,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195326 (CHEMBL3935228) Show SMILES CCOC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(c2)[N+]([O-])=O)c1 Show InChI InChI=1S/C21H23FN4O5/c1-3-31-21(28)15-5-7-18(25-10-8-24(2)9-11-25)17(12-15)23-20(27)14-4-6-16(22)19(13-14)26(29)30/h4-7,12-13H,3,8-11H2,1-2H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195432 (CHEMBL3957478) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)C(=O)Oc1ccccc1 Show InChI InChI=1S/C26H26ClFN4O3/c1-16-23(27)19(15-20(29)24(16)28)25(33)30-21-14-17(26(34)35-18-6-4-3-5-7-18)8-9-22(21)32-12-10-31(2)11-13-32/h3-9,14-15H,10-13,29H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208389 (CHEMBL3884527) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)C(C)(C)N)cc1 Show InChI InChI=1S/C29H34ClFN6O2/c1-17-25(30)21(16-22(32)26(17)31)27(38)35-23-15-19(7-10-24(23)37-13-11-36(4)12-14-37)18-5-8-20(9-6-18)34-28(39)29(2,3)33/h5-10,15-16H,11-14,32-33H2,1-4H3,(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50454122 (CHEMBL4206413) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc(cc12)C(F)(F)F |c:4| Show InChI InChI=1S/C16H18F3N5S2/c1-15(2)8-20-14(26-15)24-5-3-23(4-6-24)12-10-7-11(16(17,18)19)25-13(10)22-9-21-12/h7,9H,3-6,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of FITC-MBM1 from full length human menin measured after 1 hr by fluorescence polarization assay				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195362 (CHEMBL3907289) Show SMILES COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 Show InChI InChI=1S/C21H24ClFN4O3/c1-12-18(22)14(11-15(24)19(12)23)20(28)25-16-10-13(21(29)30-3)4-5-17(16)27-8-6-26(2)7-9-27/h4-5,10-11H,6-9,24H2,1-3H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208395 (CHEMBL3884136) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccccc1 Show InChI InChI=1S/C25H26ClFN4O/c1-16-23(26)19(15-20(28)24(16)27)25(32)29-21-14-18(17-6-4-3-5-7-17)8-9-22(21)31-12-10-30(2)11-13-31/h3-9,14-15H,10-13,28H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208392 (CHEMBL3885308) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)CCN)cc1 Show InChI InChI=1S/C28H32ClFN6O2/c1-17-26(29)21(16-22(32)27(17)30)28(38)34-23-15-19(5-8-24(23)36-13-11-35(2)12-14-36)18-3-6-20(7-4-18)33-25(37)9-10-31/h3-8,15-16H,9-14,31-32H2,1-2H3,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195369 (CHEMBL3962459) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)C(=O)OC1CCCCC1 Show InChI InChI=1S/C26H32ClFN4O3/c1-16-23(27)19(15-20(29)24(16)28)25(33)30-21-14-17(26(34)35-18-6-4-3-5-7-18)8-9-22(21)32-12-10-31(2)11-13-32/h8-9,14-15,18H,3-7,10-13,29H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208393 (CHEMBL3885025) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)CN)cc1 Show InChI InChI=1S/C27H30ClFN6O2/c1-16-25(28)20(14-21(31)26(16)29)27(37)33-22-13-18(5-8-23(22)35-11-9-34(2)10-12-35)17-3-6-19(7-4-17)32-24(36)15-30/h3-8,13-14H,9-12,15,30-31H2,1-2H3,(H,32,36)(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208384 (CHEMBL3884212) Show SMILES COC(=O)c1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 Show InChI InChI=1S/C27H28ClFN4O3/c1-16-24(28)20(15-21(30)25(16)29)26(34)31-22-14-19(17-4-6-18(7-5-17)27(35)36-3)8-9-23(22)33-12-10-32(2)11-13-33/h4-9,14-15H,10-13,30H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208379 (CHEMBL3885048) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C27H29ClFN5O2/c1-16-25(28)21(15-22(30)26(16)29)27(36)32-23-14-19(18-4-7-20(8-5-18)31-17(2)35)6-9-24(23)34-12-10-33(3)11-13-34/h4-9,14-15H,10-13,30H2,1-3H3,(H,31,35)(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208391 (CHEMBL3884230) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)C2CC2)cc1 Show InChI InChI=1S/C29H31ClFN5O2/c1-17-26(30)22(16-23(32)27(17)31)29(38)34-24-15-20(7-10-25(24)36-13-11-35(2)12-14-36)18-5-8-21(9-6-18)33-28(37)19-3-4-19/h5-10,15-16,19H,3-4,11-14,32H2,1-2H3,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208365 (CHEMBL3885462) Show SMILES CCCC(=O)Nc1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 Show InChI InChI=1S/C29H33ClFN5O2/c1-4-5-26(37)33-21-9-6-19(7-10-21)20-8-11-25(36-14-12-35(3)13-15-36)24(16-20)34-29(38)22-17-23(32)28(31)18(2)27(22)30/h6-11,16-17H,4-5,12-15,32H2,1-3H3,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208366 (CHEMBL3885279) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(c(F)c(C)c1Cl)[N+]([O-])=O)-c1ccncc1 Show InChI InChI=1S/C24H23ClFN5O3/c1-15-22(25)18(14-21(23(15)26)31(33)34)24(32)28-19-13-17(16-5-7-27-8-6-16)3-4-20(19)30-11-9-29(2)10-12-30/h3-8,13-14H,9-12H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208376 (CHEMBL3883988) Show SMILES CC(NC(=O)OC(C)(C)C)C(=O)Nc1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 Show InChI InChI=1S/C33H40ClFN6O4/c1-19-28(34)24(18-25(36)29(19)35)31(43)39-26-17-22(9-12-27(26)41-15-13-40(6)14-16-41)21-7-10-23(11-8-21)38-30(42)20(2)37-32(44)45-33(3,4)5/h7-12,17-18,20H,13-16,36H2,1-6H3,(H,37,44)(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208373 (CHEMBL3884933) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(NC(=O)CCCNC(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C34H42ClFN6O4/c1-21-30(35)25(20-26(37)31(21)36)32(44)40-27-19-23(10-13-28(27)42-17-15-41(5)16-18-42)22-8-11-24(12-9-22)39-29(43)7-6-14-38-33(45)46-34(2,3)4/h8-13,19-20H,6-7,14-18,37H2,1-5H3,(H,38,45)(H,39,43)(H,40,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208378 (CHEMBL3884501) Show SMILES CCC(=O)Nc1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 Show InChI InChI=1S/C28H31ClFN5O2/c1-4-25(36)32-20-8-5-18(6-9-20)19-7-10-24(35-13-11-34(3)12-14-35)23(15-19)33-28(37)21-16-22(31)27(30)17(2)26(21)29/h5-10,15-16H,4,11-14,31H2,1-3H3,(H,32,36)(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50208372 (CHEMBL3885241) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-c1ccc(N)cc1 Show InChI InChI=1S/C25H27ClFN5O/c1-15-23(26)19(14-20(29)24(15)27)25(33)30-21-13-17(16-3-6-18(28)7-4-16)5-8-22(21)32-11-9-31(2)10-12-32/h3-8,13-14H,9-12,28-29H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
					More data for this Ligand-Target Pair

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