Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus) | BDBM123410 (US8741926, 82 | US8754106, 82 | US8754106, 91) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123407 (US8741926, 91) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.0500 | -59.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123413 (US8741926, 94 | US8754106, 94) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123415 (US8741926, 95 | US8754106, 95) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | -58.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123415 (US8741926, 95 | US8754106, 95) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124106 (US8754106, 56) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236571 (US9365582, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236563 (US9365582, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123413 (US8741926, 94 | US8754106, 94) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | -58.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123411 (US8741926, 56) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | -58.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236566 (US9365582, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236565 (US9365582, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124107 (US8754105, 23) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | -56.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236573 (US9365582, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123414 (US8741926, 48 | US8754106, 48) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123414 (US8741926, 48 | US8754106, 48) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.25 | -55.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123412 (US8741926, 57 | US8754106, 57) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123412 (US8741926, 57 | US8754106, 57) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | -55.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236569 (US9365582, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50336504 ((2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB US Patent | 0.5 | -54.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50336504 ((2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | US Patent | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236567 (US9365582, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124112 (US8754105, 25) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.40 | -50.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123408 (US8741926, 55) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5 | -48.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124105 (US8754106, 55) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236568 (US9365582, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123410 (US8741926, 82 | US8754106, 82 | US8754106, 91) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754106 (2014) BindingDB Entry DOI: 10.7270/Q2V40SWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123410 (US8741926, 82 | US8754106, 82 | US8754106, 91) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 9.40 | -46.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236570 (US9365582, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 17 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236562 (US9365582, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 37 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124111 (US8754105, 24) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 40 | -42.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124110 (US8754105, 17) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 43 | -42.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236564 (US9365582, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 46 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM236572 (US9365582, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 58 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124109 (US8754105, 16) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.00E+3 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123409 (US8741926, 81) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.00E+3 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Janssen R&D Ireland; Medivir AB US Patent | Assay Description The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ... | US Patent US8741926 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124108 (US8754105, 22) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.07E+3 | -34.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50163391 (CHEMBL195725 | {3-[(4-Amino-benzenesulfonyl)-isobu...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Binding affinity against HIV-1 protease | J Med Chem 48: 1965-73 (2005) Article DOI: 10.1021/jm049454n BindingDB Entry DOI: 10.7270/Q2668CQJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50163376 (CHEMBL193429 | {(1S,2R)-1-Benzyl-2-hydroxy-3-[isob...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Binding affinity against HIV-1 protease | J Med Chem 48: 1965-73 (2005) Article DOI: 10.1021/jm049454n BindingDB Entry DOI: 10.7270/Q2668CQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50163379 (((1S,2R)-1-Benzyl-2-hydroxy-3-{isobutyl-[2-(2-pyrr...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Binding affinity against HIV-1 protease | J Med Chem 48: 1965-73 (2005) Article DOI: 10.1021/jm049454n BindingDB Entry DOI: 10.7270/Q2668CQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236573 (US9365582, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236572 (US9365582, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236570 (US9365582, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236569 (US9365582, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236568 (US9365582, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.81E+3 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236567 (US9365582, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236566 (US9365582, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236565 (US9365582, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236564 (US9365582, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.26E+3 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM236563 (US9365582, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9365582 (2016) BindingDB Entry DOI: 10.7270/Q2VM4B5G | |||||||||||
More data for this Ligand-Target Pair |
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