Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50273935 ((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50273935 ((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50348870 (CHEMBL1808302) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50273933 ((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50348869 (CHEMBL1808300) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50348869 (CHEMBL1808300) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 171 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50348871 (CHEMBL1808303) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50348871 (CHEMBL1808303) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50273933 ((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 352 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50348872 (CHEMBL1808304) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 367 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50348872 (CHEMBL1808304) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 384 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50348870 (CHEMBL1808302) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 486 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50348868 (CHEMBL1808301) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50348867 (CHEMBL1808299) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50348870 (CHEMBL1808302) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50348868 (CHEMBL1808301) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50348867 (CHEMBL1808299) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50348869 (CHEMBL1808300) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50273935 ((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50273933 ((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50348872 (CHEMBL1808304) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50348871 (CHEMBL1808303) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cells coexpressing human recombinant DOR after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50348867 (CHEMBL1808299) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50348868 (CHEMBL1808301) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism Curated by ChEMBL | Assay Description Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cells coexpressing human recombinant KOP after 2 hrs by liquid scintilla... | Bioorg Med Chem 19: 4330-7 (2011) Article DOI: 10.1016/j.bmc.2011.05.035 BindingDB Entry DOI: 10.7270/Q2902452 | |||||||||||
More data for this Ligand-Target Pair |