BindingDB PrimarySearch

Found 53 hits with Last Name = 'gesell' and Initial = 'j'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31225 (2-phenoxybenzoyltryptophan derivative, R5C3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	100	-39.7	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31224 (2-phenoxybenzoyltryptophan derivative, R5C2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	200	-38.0	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31216 (2-phenoxybenzoyltryptophan derivative, R3C2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	400	-36.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31209 (2-phenoxybenzoyltryptophan derivative, R1C3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	500	-35.7	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31210 (2-phenoxybenzoyltryptophan derivative, R1C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-35.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31220 (2-phenoxybenzoyltryptophan derivative, R4C2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-35.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31226 (2-phenoxybenzoyltryptophan derivative, R5C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-35.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31213 (2-phenoxybenzoyltryptophan derivative, R2C3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-35.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31221 (2-phenoxybenzoyltryptophan derivative, R4C3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-35.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31217 (2-phenoxybenzoyltryptophan derivative, R3C3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	800	-34.6	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31212 (2-phenoxybenzoyltryptophan derivative, R2C2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	800	-34.6	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31208 (2-phenoxybenzoyltryptophan derivative, R1C2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	800	-34.6	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31214 (2-phenoxybenzoyltryptophan derivative, R2C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	-34.0	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31222 (2-phenoxybenzoyltryptophan derivative, R4C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	-34.0	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31218 (2-phenoxybenzoyltryptophan derivative, R3C4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	-32.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31207 (2-phenoxybenzoyltryptophan derivative, R1C1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	-31.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31211 (2-phenoxybenzoyltryptophan derivative, R2C1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	-29.6	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31219 (2-phenoxybenzoyltryptophan derivative, R4C1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	-28.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31223 (2-phenoxybenzoyltryptophan derivative, R5C1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	-28.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31215 (2-phenoxybenzoyltryptophan derivative, R3C1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	-26.6	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
Schering-Plough Research Institute					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM13934 (Atazanavir \| BMS 232632 \| CGP 73547 \| CHEMBL1163 \|...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190623 (CHEMBL3828743) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190624 (CHEMBL3828417) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190625 (CHEMBL3828552) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190638 (CHEMBL3828119) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190631 (CHEMBL3828166) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190639 (CHEMBL3827524) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190629 (CHEMBL3828678) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190636 (CHEMBL3828275) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190641 (CHEMBL3827205) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190640 (CHEMBL3828355) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190642 (CHEMBL3827353) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190627 (CHEMBL3827958) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190626 (CHEMBL3827319) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190637 (CHEMBL3827348) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190628 (CHEMBL3827975) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190632 (CHEMBL3827450) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190630 (CHEMBL3827960) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190633 (CHEMBL3827407) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190634 (CHEMBL3828494) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50190635 (CHEMBL3827668) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...				ACS Med Chem Lett 7: 702-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00135 BindingDB Entry DOI: 10.7270/Q28W3G74
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2C8 in human liver microsomes measured after concurrent incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2C8 in human liver microsomes measured after compound pre-incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2CJ in human liver microsomes measured after compound pre-incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes measured after compound pre-incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP1A2 in human liver microsomes measured after compound pre-incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes measured after concurrent incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes measured after compound pre-incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2CJ in human liver microsomes measured after concurrent incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50444436 (CHEMBL3092124) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes measured after concurrent incubation				Bioorg Med Chem Lett 23: 6585-7 (2013) Article DOI: 10.1016/j.bmcl.2013.10.060 BindingDB Entry DOI: 10.7270/Q2GF0W06
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

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