Compile Data Set for Download or QSAR

Found 147 hits with Last Name = 'halfpenny' and Initial = 'pr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23 Show InChI InChI=1S/C28H36N2O2/c1-19-21-10-5-8-20-9-6-11-22(26(20)21)25(19)27(31)29(2)23-12-14-28(13-7-17-32-28)18-24(23)30-15-3-4-16-30/h5-6,8-11,19,23-25H,3-4,7,12-18H2,1-2H3/t19?,23-,24-,25?,28?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000091 ((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...) Show SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 |TLB:6:5:13.21.15:11,14:13:11:5.3.4,THB:20:21:11:5.3.4| Show InChI InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008858 (2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50367937 (CHEMBL1202931) Show SMILES CN([C@@H]1CC[C@]2(CCCO2)C[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 |r| Show InChI InChI=1S/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1				J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008852 (2-Methyl-acenaphthene-1-carboxylic acid (7-imidazo...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCNC2)c2cccc3cccc1c23 Show InChI InChI=1S/C27H35N3O2/c1-18-20-8-3-6-19-7-4-9-21(25(19)20)24(18)26(31)29(2)22-10-12-27(11-5-15-32-27)16-23(22)30-14-13-28-17-30/h3-4,6-9,18,22-24,28H,5,10-17H2,1-2H3/t18?,22-,23-,24?,27?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000091 ((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...) Show SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 |TLB:6:5:13.21.15:11,14:13:11:5.3.4,THB:20:21:11:5.3.4| Show InChI InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor mu 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards mu opioid receptor was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (GUINEA PIG)	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor mu 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018786 (CHEMBL538309 | N-(2-Azocan-1-yl-cyclohexyl)-N-meth...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1 Show InChI InChI=1S/C22H31Cl3N2O2/c1-26(21(28)15-29-16-13-17(23)22(25)18(24)14-16)19-9-5-6-10-20(19)27-11-7-3-2-4-8-12-27/h13-14,19-20H,2-12,15H2,1H3/t19-,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008857 (CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C26H34N2O2/c1-27(25(29)18-21-10-6-9-20-8-2-3-11-22(20)21)23-12-14-26(13-7-17-30-26)19-24(23)28-15-4-5-16-28/h2-3,6,8-11,23-24H,4-5,7,12-19H2,1H3/t23-,24-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1				J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018768 (CHEMBL556957 | N-(2-Azepan-1-yl-cyclohexyl)-2-(4-c...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)COc1cc(C)c(Cl)c(C)c1 Show InChI InChI=1S/C23H35ClN2O2/c1-17-14-19(15-18(2)23(17)24)28-16-22(27)25(3)20-10-6-7-11-21(20)26-12-8-4-5-9-13-26/h14-15,20-21H,4-13,16H2,1-3H3/t20-,21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018762 (2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cy...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C21H28N2O2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018767 (CHEMBL535581 | N-(2-Azocan-1-yl-cyclohexyl)-N-meth...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1Cl Show InChI InChI=1S/C22H30Cl4N2O2/c1-27(19(29)14-30-18-13-15(23)20(24)22(26)21(18)25)16-9-5-6-10-17(16)28-11-7-3-2-4-8-12-28/h13,16-17H,2-12,14H2,1H3/t16-,17-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018771 (CHEMBL535801 | N-(2-Azepan-1-yl-cyclohexyl)-N-meth...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1Cl Show InChI InChI=1S/C21H28Cl4N2O2/c1-26(15-8-4-5-9-16(15)27-10-6-2-3-7-11-27)18(28)13-29-17-12-14(22)19(23)21(25)20(17)24/h12,15-16H,2-11,13H2,1H3/t15-,16-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017495 (2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2O2S/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Effect on plasma amine oxidase (0.1 uM) after 15 min of incubation at pH 7.2				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018781 (CHEMBL557426 | N-Methyl-N-(2-pyrrolidin-1-yl-cyclo...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1 Show InChI InChI=1S/C19H25Cl3N2O2/c1-23(16-6-2-3-7-17(16)24-8-4-5-9-24)18(25)12-26-13-10-14(20)19(22)15(21)11-13/h10-11,16-17H,2-9,12H2,1H3/t16-,17-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018762 (2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cy...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C21H28N2O2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Effect on plasma amine oxidase (0.1 uM) after 60 min of incubation at pH 7.2				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017500 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2OS/c1-23(19-9-3-2-4-10-20(19)24-13-5-6-14-24)22(25)16-17-8-7-11-21-18(17)12-15-26-21/h7-8,11-12,15,19-20H,2-6,9-10,13-14,16H2,1H3/t19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018762 (2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cy...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C21H28N2O2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Effect on plasma amine oxidase (0.1 uM) after 0 min of incubation at pH 7.2				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50013147 (2-Benzo[b]thiophen-4-yl-N-(4,5-dimethoxy-2-pyrroli...) Show SMILES CO[C@H]1CC([C@H](C[C@H]1OC)N1CCCC1)N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C23H32N2O3S/c1-24(23(26)13-16-7-6-8-22-17(16)9-12-29-22)18-14-20(27-2)21(28-3)15-19(18)25-10-4-5-11-25/h6-9,12,18-21H,4-5,10-11,13-15H2,1-3H3/t18?,19-,20-,21+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1				J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017488 (2-Benzofuran-4-yl-N-(4,5-dimethoxy-2-pyrrolidin-1-...) Show SMILES CO[C@H]1C[C@@H]([C@H](C[C@H]1OC)N1CCCC1)N(C)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C23H32N2O4/c1-24(23(26)13-16-7-6-8-20-17(16)9-12-29-20)18-14-21(27-2)22(28-3)15-19(18)25-10-4-5-11-25/h6-9,12,18-19,21-22H,4-5,10-11,13-15H2,1-3H3/t18-,19-,21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017494 (2-Benzo[b]thiophen-7-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2ccsc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-9-2-3-10-19(18)23-12-4-5-13-23)20(24)15-17-8-6-7-16-11-14-25-21(16)17/h6-8,11,14,18-19H,2-5,9-10,12-13,15H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H30Cl2N2O2/c1-25(21(27)14-16-5-6-17(23)18(24)13-16)19-7-9-22(8-4-12-28-22)15-20(19)26-10-2-3-11-26/h5-6,13,19-20H,2-4,7-12,14-15H2,1H3/t19-,20-,22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017498 (2-Benzofuran-4-yl-N-[2-(3-hydroxymethyl-pyrrolidin...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C22H30N2O3/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50013147 (2-Benzo[b]thiophen-4-yl-N-(4,5-dimethoxy-2-pyrroli...) Show SMILES CO[C@H]1CC([C@H](C[C@H]1OC)N1CCCC1)N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C23H32N2O3S/c1-24(23(26)13-16-7-6-8-22-17(16)9-12-29-22)18-14-20(27-2)21(28-3)15-19(18)25-10-4-5-11-25/h6-9,12,18-21H,4-5,10-11,13-15H2,1-3H3/t18?,19-,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50018778 (2-Benzo[b]thiophen-4-yl-N-methyl-N-[2-(methyl-phen...) Show SMILES CN(CCc1ccccc1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C26H32N2OS/c1-27(17-15-20-9-4-3-5-10-20)23-12-6-7-13-24(23)28(2)26(29)19-21-11-8-14-25-22(21)16-18-30-25/h3-5,8-11,14,16,18,23-24H,6-7,12-13,15,17,19H2,1-2H3/t23-,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor mu 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018784 (CHEMBL559217 | N-(2-Azepan-1-yl-cyclohexyl)-2-benz...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C23H32N2O2/c1-24(23(26)17-18-9-8-12-22-19(18)13-16-27-22)20-10-4-5-11-21(20)25-14-6-2-3-7-15-25/h8-9,12-13,16,20-21H,2-7,10-11,14-15,17H2,1H3/t20-,21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018778 (2-Benzo[b]thiophen-4-yl-N-methyl-N-[2-(methyl-phen...) Show SMILES CN(CCc1ccccc1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C26H32N2OS/c1-27(17-15-20-9-4-3-5-10-20)23-12-6-7-13-24(23)28(2)26(29)19-21-11-8-14-25-22(21)16-18-30-25/h3-5,8-11,14,16,18,23-24H,6-7,12-13,15,17,19H2,1-2H3/t23-,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018764 (2-(3,4-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H26Cl2N2O2/c1-22(17-6-2-3-7-18(17)23-10-4-5-11-23)19(24)13-25-14-8-9-15(20)16(21)12-14/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018788 (CHEMBL537169 | N-(2-Azepan-1-yl-cyclohexyl)-2-benz...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C23H32N2OS/c1-24(23(26)17-18-9-8-12-22-19(18)13-16-27-22)20-10-4-5-11-21(20)25-14-6-2-3-7-15-25/h8-9,12-13,16,20-21H,2-7,10-11,14-15,17H2,1H3/t20-,21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018783 (CHEMBL539582 | N-[2-(Allyl-methyl-amino)-cyclohexy...) Show SMILES CN(CC=C)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-4-13-22(2)18-9-5-6-10-19(18)23(3)21(24)15-16-8-7-11-20-17(16)12-14-25-20/h4,7-8,11-12,14,18-19H,1,5-6,9-10,13,15H2,2-3H3/t18-,19-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor mu 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017504 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=S)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2S2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017499 (2-Benzo[b]thiophen-3-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1csc2ccccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-9-3-4-10-19(18)23-12-6-7-13-23)21(24)14-16-15-25-20-11-5-2-8-17(16)20/h2,5,8,11,15,18-19H,3-4,6-7,9-10,12-14H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018776 (CHEMBL537615 | N-(2-Azepan-1-yl-cyclohexyl)-2-(3,5...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)COc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H30Cl2N2O2/c1-24(21(26)15-27-18-13-16(22)12-17(23)14-18)19-8-4-5-9-20(19)25-10-6-2-3-7-11-25/h12-14,19-20H,2-11,15H2,1H3/t19-,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018763 (2-(1H-Indol-3-yl)-N-methyl-N-(2-pyrrolidin-1-yl-cy...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C21H29N3O/c1-23(19-10-4-5-11-20(19)24-12-6-7-13-24)21(25)14-16-15-22-18-9-3-2-8-17(16)18/h2-3,8-9,15,19-20,22H,4-7,10-14H2,1H3/t19-,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50018779 (2-Benzo[b]thiophen-4-yl-N-methyl-N-{2-[methyl-(2-t...) Show SMILES CN(CCc1cccs1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C24H30N2OS2/c1-25(14-12-19-8-6-15-28-19)21-9-3-4-10-22(21)26(2)24(27)17-18-7-5-11-23-20(18)13-16-29-23/h5-8,11,13,15-16,21-22H,3-4,9-10,12,14,17H2,1-2H3/t21-,22-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor mu 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50018779 (2-Benzo[b]thiophen-4-yl-N-methyl-N-{2-[methyl-(2-t...) Show SMILES CN(CCc1cccs1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C24H30N2OS2/c1-25(14-12-19-8-6-15-28-19)21-9-3-4-10-22(21)26(2)24(27)17-18-7-5-11-23-20(18)13-16-29-23/h5-8,11,13,15-16,21-22H,3-4,9-10,12,14,17H2,1-2H3/t21-,22-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity for the Opioid receptor kappa 1				J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK
					More data for this Ligand-Target Pair

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