Compile Data Set for Download or QSAR

Found 46 hits with Last Name = 'iwayama' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50101813 (CHEBI:31399 | Cilnidipine) Show SMILES COCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC\C=C\c1ccccc1 |c:7,12| Show InChI InChI=1S/C27H28N2O7/c1-18-23(26(30)35-14-8-11-20-9-5-4-6-10-20)25(21-12-7-13-22(17-21)29(32)33)24(19(2)28-18)27(31)36-16-15-34-3/h4-13,17,25,28H,14-16H2,1-3H3/b11-8+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ring				Bioorg Med Chem Lett 21: 3317-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.007 BindingDB Entry DOI: 10.7270/Q2N019CJ
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211650 (3-(4-(4-((1-(2-chlorocyclopent-1-enyl)ethoxy)carbo...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCC(O)=O)cc1)C1=C(Cl)CCC1 |c:26| Show InChI InChI=1S/C21H23ClN2O5S/c1-13(16-3-2-4-17(16)22)29-21(27)23-18-11-28-24-20(18)15-7-5-14(6-8-15)12-30-10-9-19(25)26/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,23,27)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50475659 (CHEMBL508181) Show SMILES CC1=C(C(C(C(=O)OC\C=C\c2ccccc2)=C(C)N1)c1cccc(c1)[N+]([O-])=O)C(O)=O |t:1,17| Show InChI InChI=1S/C24H22N2O6/c1-15-20(23(27)28)22(18-11-6-12-19(14-18)26(30)31)21(16(2)25-15)24(29)32-13-7-10-17-8-4-3-5-9-17/h3-12,14,22,25H,13H2,1-2H3,(H,27,28)/b10-7+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ring				Bioorg Med Chem Lett 21: 3317-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.007 BindingDB Entry DOI: 10.7270/Q2N019CJ
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211649 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O5S/c1-14(17-4-2-3-5-18(17)23)30-22(28)24-19-12-29-25-21(19)16-8-6-15(7-9-16)13-31-11-10-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211647 (3-(4-(4-((1-(2-chlorocyclohex-1-enyl)ethoxy)carbon...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCC(O)=O)cc1)C1=C(Cl)CCCC1 |c:26| Show InChI InChI=1S/C22H25ClN2O5S/c1-14(17-4-2-3-5-18(17)23)30-22(28)24-19-12-29-25-21(19)16-8-6-15(7-9-16)13-31-11-10-20(26)27/h6-9,12,14H,2-5,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211646 (5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CCCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C23H23ClN2O5/c1-15(18-7-3-4-8-19(18)24)31-23(29)25-20-14-30-26-22(20)17-12-10-16(11-13-17)6-2-5-9-21(27)28/h3-4,7-8,10-15H,2,5-6,9H2,1H3,(H,25,29)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211655 (4-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(NC(=O)CCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H20ClN3O6/c1-13(16-4-2-3-5-17(16)23)32-22(30)25-18-12-31-26-21(18)14-6-8-15(9-7-14)24-19(27)10-11-20(28)29/h2-9,12-13H,10-11H2,1H3,(H,24,27)(H,25,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211645 (2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCS(O)(=O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C21H21ClN2O6S2/c1-14(17-4-2-3-5-18(17)22)30-21(25)23-19-12-29-24-20(19)16-8-6-15(7-9-16)13-31-10-11-32(26,27)28/h2-9,12,14H,10-11,13H2,1H3,(H,23,25)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211651 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1cnoc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O5S/c1-14(17-4-2-3-5-18(17)23)29-22(28)25-19-12-24-30-21(19)16-8-6-15(7-9-16)13-31-11-10-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,25,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211648 (2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CCSCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O5S/c1-14(17-4-2-3-5-18(17)23)30-22(28)24-19-12-29-25-21(19)16-8-6-15(7-9-16)10-11-31-13-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211653 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CS(=O)(=O)CCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O7S/c1-14(17-4-2-3-5-18(17)23)32-22(28)24-19-12-31-25-21(19)16-8-6-15(7-9-16)13-33(29,30)11-10-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211654 (5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CCC(C)(C)CC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C25H27ClN2O5/c1-16(19-6-4-5-7-20(19)26)33-24(31)27-21-15-32-28-23(21)18-10-8-17(9-11-18)12-13-25(2,3)14-22(29)30/h4-11,15-16H,12-14H2,1-3H3,(H,27,31)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211648 (2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CCSCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O5S/c1-14(17-4-2-3-5-18(17)23)30-22(28)24-19-12-29-25-21(19)16-8-6-15(7-9-16)10-11-31-13-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211650 (3-(4-(4-((1-(2-chlorocyclopent-1-enyl)ethoxy)carbo...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCC(O)=O)cc1)C1=C(Cl)CCC1 |c:26| Show InChI InChI=1S/C21H23ClN2O5S/c1-13(16-3-2-4-17(16)22)29-21(27)23-18-11-28-24-20(18)15-7-5-14(6-8-15)12-30-10-9-19(25)26/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,23,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211655 (4-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(NC(=O)CCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H20ClN3O6/c1-13(16-4-2-3-5-17(16)23)32-22(30)25-18-12-31-26-21(18)14-6-8-15(9-7-14)24-19(27)10-11-20(28)29/h2-9,12-13H,10-11H2,1H3,(H,24,27)(H,25,30)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50170859 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...) Show SMILES CC(OC(=O)Nc1c(C)noc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C23H23ClN2O5S/c1-14-21(25-23(29)30-15(2)18-5-3-4-6-19(18)24)22(31-26-14)17-9-7-16(8-10-17)13-32-12-11-20(27)28/h3-10,15H,11-13H2,1-2H3,(H,25,29)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211647 (3-(4-(4-((1-(2-chlorocyclohex-1-enyl)ethoxy)carbon...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCC(O)=O)cc1)C1=C(Cl)CCCC1 |c:26| Show InChI InChI=1S/C22H25ClN2O5S/c1-14(17-4-2-3-5-18(17)23)30-22(28)24-19-12-29-25-21(19)16-8-6-15(7-9-16)13-31-11-10-20(26)27/h6-9,12,14H,2-5,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211646 (5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CCCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C23H23ClN2O5/c1-15(18-7-3-4-8-19(18)24)31-23(29)25-20-14-30-26-22(20)17-12-10-16(11-13-17)6-2-5-9-21(27)28/h3-4,7-8,10-15H,2,5-6,9H2,1H3,(H,25,29)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211649 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O5S/c1-14(17-4-2-3-5-18(17)23)30-22(28)24-19-12-29-25-21(19)16-8-6-15(7-9-16)13-31-11-10-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211651 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1cnoc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O5S/c1-14(17-4-2-3-5-18(17)23)29-22(28)25-19-12-24-30-21(19)16-8-6-15(7-9-16)13-31-11-10-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,25,28)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211653 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CS(=O)(=O)CCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C22H21ClN2O7S/c1-14(17-4-2-3-5-18(17)23)32-22(28)24-19-12-31-25-21(19)16-8-6-15(7-9-16)13-33(29,30)11-10-20(26)27/h2-9,12,14H,10-11,13H2,1H3,(H,24,28)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211654 (5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CCC(C)(C)CC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C25H27ClN2O5/c1-16(19-6-4-5-7-20(19)26)33-24(31)27-21-15-32-28-23(21)18-10-8-17(9-11-18)12-13-25(2,3)14-22(29)30/h4-11,15-16H,12-14H2,1-3H3,(H,27,31)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM50052428 (2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-i...) Show SMILES Fc1c2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c(F)c(F)c1F Show InChI InChI=1S/C13H6F4N2O4/c14-7-5-6(8(15)10(17)9(7)16)13(23)19(12(5)22)3-1-2-4(20)18-11(3)21/h3H,1-2H2,(H,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology Curated by ChEMBL					Assay Description Inhibitory activity against TNF-alpha production				J Med Chem 39: 3044-5 (1996) Article DOI: 10.1021/jm960284r BindingDB Entry DOI: 10.7270/Q2RB73PR
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211645 (2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...) Show SMILES CC(OC(=O)Nc1conc1-c1ccc(CSCCS(O)(=O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C21H21ClN2O6S2/c1-14(17-4-2-3-5-18(17)22)30-21(25)23-19-12-29-24-20(19)16-8-6-15(7-9-16)13-31-10-11-32(26,27)28/h2-9,12,14H,10-11,13H2,1H3,(H,23,25)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50170859 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...) Show SMILES CC(OC(=O)Nc1c(C)noc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C23H23ClN2O5S/c1-14-21(25-23(29)30-15(2)18-5-3-4-6-19(18)24)22(31-26-14)17-9-7-16(8-10-17)13-32-12-11-20(27)28/h3-10,15H,11-13H2,1-2H3,(H,25,29)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383776 (CHEMBL2030594) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1ccc(Cl)c(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C25H23Cl2NO6/c1-32-25(33-2)22-21(24(31)34-12-6-9-15-7-4-3-5-8-15)20(17(14-28-22)23(29)30)16-10-11-18(26)19(27)13-16/h3-11,13-14,17,20,25H,12H2,1-2H3,(H,29,30)/b9-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383765 (CHEMBL2030603) Show SMILES COc1c(Cl)cc(cc1Cl)C1C(C=NC=C1C(=O)OC\C=C\c1ccccc1)C(O)=O |c:13,15| Show InChI InChI=1S/C23H19Cl2NO5/c1-30-21-18(24)10-15(11-19(21)25)20-16(22(27)28)12-26-13-17(20)23(29)31-9-5-8-14-6-3-2-4-7-14/h2-8,10-13,16,20H,9H2,1H3,(H,27,28)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383765 (CHEMBL2030603) Show SMILES COc1c(Cl)cc(cc1Cl)C1C(C=NC=C1C(=O)OC\C=C\c1ccccc1)C(O)=O |c:13,15| Show InChI InChI=1S/C23H19Cl2NO5/c1-30-21-18(24)10-15(11-19(21)25)20-16(22(27)28)12-26-13-17(20)23(29)31-9-5-8-14-6-3-2-4-7-14/h2-8,10-13,16,20H,9H2,1H3,(H,27,28)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383769 (CHEMBL2030600) Show SMILES OC(=O)C1C=NC=C(C1c1ccc(Cl)c(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:4,6| Show InChI InChI=1S/C22H17Cl2NO4/c23-18-9-8-15(11-19(18)24)20-16(21(26)27)12-25-13-17(20)22(28)29-10-4-7-14-5-2-1-3-6-14/h1-9,11-13,16,20H,10H2,(H,26,27)/b7-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383765 (CHEMBL2030603) Show SMILES COc1c(Cl)cc(cc1Cl)C1C(C=NC=C1C(=O)OC\C=C\c1ccccc1)C(O)=O |c:13,15| Show InChI InChI=1S/C23H19Cl2NO5/c1-30-21-18(24)10-15(11-19(21)25)20-16(22(27)28)12-26-13-17(20)23(29)31-9-5-8-14-6-3-2-4-7-14/h2-8,10-13,16,20H,9H2,1H3,(H,27,28)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383775 (CHEMBL2030593) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1cc(Cl)cc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C25H23Cl2NO6/c1-32-25(33-2)22-21(24(31)34-10-6-9-15-7-4-3-5-8-15)20(19(14-28-22)23(29)30)16-11-17(26)13-18(27)12-16/h3-9,11-14,19-20,25H,10H2,1-2H3,(H,29,30)/b9-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383774 (CHEMBL2030592) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1ccc(Cl)cc1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C25H24ClNO6/c1-31-25(32-2)22-21(24(30)33-14-6-9-16-7-4-3-5-8-16)20(19(15-27-22)23(28)29)17-10-12-18(26)13-11-17/h3-13,15,19-20,25H,14H2,1-2H3,(H,28,29)/b9-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383766 (CHEMBL2030597) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1cccc(c1)C(F)(F)F)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C26H24F3NO6/c1-34-25(35-2)22-21(24(33)36-13-7-10-16-8-4-3-5-9-16)20(19(15-30-22)23(31)32)17-11-6-12-18(14-17)26(27,28)29/h3-12,14-15,19-20,25H,13H2,1-2H3,(H,31,32)/b10-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383773 (CHEMBL2030591) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C25H24ClNO6/c1-31-25(32-2)22-21(24(30)33-13-7-10-16-8-4-3-5-9-16)20(19(15-27-22)23(28)29)17-11-6-12-18(26)14-17/h3-12,14-15,19-20,25H,13H2,1-2H3,(H,28,29)/b10-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383778 (CHEMBL2030596) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1cc(Cl)c(OC)c(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C26H25Cl2NO7/c1-33-23-18(27)12-16(13-19(23)28)20-17(24(30)31)14-29-22(26(34-2)35-3)21(20)25(32)36-11-7-10-15-8-5-4-6-9-15/h4-10,12-14,17,20,26H,11H2,1-3H3,(H,30,31)/b10-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383768 (CHEMBL2030599) Show SMILES OC(=O)C1C=NC=C(C1c1ccc(Cl)cc1)C(=O)OC\C=C\c1ccccc1 |c:4,6| Show InChI InChI=1S/C22H18ClNO4/c23-17-10-8-16(9-11-17)20-18(21(25)26)13-24-14-19(20)22(27)28-12-4-7-15-5-2-1-3-6-15/h1-11,13-14,18,20H,12H2,(H,25,26)/b7-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383770 (CHEMBL2030601) Show SMILES OC(=O)C1C=NC=C(C1c1cccc(c1)C(F)(F)F)C(=O)OC\C=C\c1ccccc1 |c:4,6| Show InChI InChI=1S/C23H18F3NO4/c24-23(25,26)17-10-4-9-16(12-17)20-18(21(28)29)13-27-14-19(20)22(30)31-11-5-8-15-6-2-1-3-7-15/h1-10,12-14,18,20H,11H2,(H,28,29)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383771 (CHEMBL2030602) Show SMILES COc1ccc(cc1Cl)C1C(C=NC=C1C(=O)OC\C=C\c1ccccc1)C(O)=O |c:12,14| Show InChI InChI=1S/C23H20ClNO5/c1-29-20-10-9-16(12-19(20)24)21-17(22(26)27)13-25-14-18(21)23(28)30-11-5-8-15-6-3-2-4-7-15/h2-10,12-14,17,21H,11H2,1H3,(H,26,27)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383777 (CHEMBL2030595) Show SMILES COC(OC)C1=C(C(C(C=N1)C(O)=O)c1ccc(OC)c(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:9,t:5| Show InChI InChI=1S/C26H26ClNO7/c1-32-20-12-11-17(14-19(20)27)21-18(24(29)30)15-28-23(26(33-2)34-3)22(21)25(31)35-13-7-10-16-8-5-4-6-9-16/h4-12,14-15,18,21,26H,13H2,1-3H3,(H,29,30)/b10-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383767 (CHEMBL2030598) Show SMILES OC(=O)C1C=NC=C(C1c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:4,6| Show InChI InChI=1S/C22H18ClNO4/c23-17-10-4-9-16(12-17)20-18(21(25)26)13-24-14-19(20)22(27)28-11-5-8-15-6-2-1-3-7-15/h1-10,12-14,18,20H,11H2,(H,25,26)/b8-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50383772 (CHEMBL451812) Show SMILES COC(OC)C1=C(C(C(C(O)=O)C(C)=N1)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:13,t:5| Show InChI InChI=1S/C26H26ClNO6/c1-16-20(24(29)30)21(18-12-7-13-19(27)15-18)22(23(28-16)26(32-2)33-3)25(31)34-14-8-11-17-9-5-4-6-10-17/h4-13,15,20-21,26H,14H2,1-3H3,(H,29,30)/b11-8+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL					Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...				Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50383772 (CHEMBL451812) Show SMILES COC(OC)C1=C(C(C(C(O)=O)C(C)=N1)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:13,t:5| Show InChI InChI=1S/C26H26ClNO6/c1-16-20(24(29)30)21(18-12-7-13-19(27)15-18)22(23(28-16)26(32-2)33-3)25(31)34-14-8-11-17-9-5-4-6-10-17/h4-13,15,20-21,26H,14H2,1-3H3,(H,29,30)/b11-8+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ring				Bioorg Med Chem Lett 21: 3317-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.007 BindingDB Entry DOI: 10.7270/Q2N019CJ
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50383772 (CHEMBL451812) Show SMILES COC(OC)C1=C(C(C(C(O)=O)C(C)=N1)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:13,t:5| Show InChI InChI=1S/C26H26ClNO6/c1-16-20(24(29)30)21(18-12-7-13-19(27)15-18)22(23(28-16)26(32-2)33-3)25(31)34-14-8-11-17-9-5-4-6-10-17/h4-13,15,20-21,26H,14H2,1-3H3,(H,29,30)/b11-8+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ring				Bioorg Med Chem Lett 21: 3317-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.007 BindingDB Entry DOI: 10.7270/Q2N019CJ
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50383772 (CHEMBL451812) Show SMILES COC(OC)C1=C(C(C(C(O)=O)C(C)=N1)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1 |c:13,t:5| Show InChI InChI=1S/C26H26ClNO6/c1-16-20(24(29)30)21(18-12-7-13-19(27)15-18)22(23(28-16)26(32-2)33-3)25(31)34-14-8-11-17-9-5-4-6-10-17/h4-13,15,20-21,26H,14H2,1-3H3,(H,29,30)/b11-8+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ring				Bioorg Med Chem Lett 21: 3317-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.007 BindingDB Entry DOI: 10.7270/Q2N019CJ
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Rattus norvegicus)	BDBM50211652 (3-{2'-[1-(2-chloro-phenyl)-ethoxycarbonylamino]-bi...) Show SMILES CC(OC(=O)Nc1ccccc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C25H24ClNO4S/c1-17(20-6-2-4-8-22(20)26)31-25(30)27-23-9-5-3-7-21(23)19-12-10-18(11-13-19)16-32-15-14-24(28)29/h2-13,17H,14-16H2,1H3,(H,27,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50211652 (3-{2'-[1-(2-chloro-phenyl)-ethoxycarbonylamino]-bi...) Show SMILES CC(OC(=O)Nc1ccccc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl Show InChI InChI=1S/C25H24ClNO4S/c1-17(20-6-2-4-8-22(20)26)31-25(30)27-23-9-5-3-7-21(23)19-12-10-18(11-13-19)16-32-15-14-24(28)29/h2-13,17H,14-16H2,1H3,(H,27,30)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ajinomoto Company Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...				Bioorg Med Chem Lett 17: 3736-40 (2007) Article DOI: 10.1016/j.bmcl.2007.04.024 BindingDB Entry DOI: 10.7270/Q2CZ36T2
					More data for this Ligand-Target Pair