Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50006222 ((1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolase | J Med Chem 31: 500-3 (1988) BindingDB Entry DOI: 10.7270/Q28P61Q3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50006222 ((1S,2R,5R)-5-(6-Amino-purin-9-yl)-3-hydroxymethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50367250 (3-DEAZAARISTEROMYCIN A | CHEMBL268272) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against S-adenosyl-homocysteine hydrolase | J Med Chem 28: 471-7 (1985) BindingDB Entry DOI: 10.7270/Q21C1XF3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50405655 (CHEMBL147260) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolase | J Med Chem 31: 500-3 (1988) BindingDB Entry DOI: 10.7270/Q28P61Q3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50006215 ((1'R,2'S,3'R)-9-(2',3'-dihydroxycyclopent-4'-enyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolase | J Med Chem 31: 500-3 (1988) BindingDB Entry DOI: 10.7270/Q28P61Q3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023889 (5-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-pent-3-ene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50088426 ((1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against S-adenosyl-homocysteine hydrolase | J Med Chem 28: 471-7 (1985) BindingDB Entry DOI: 10.7270/Q21C1XF3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023879 (2-[2-(6-Amino-purin-9-yl)-ethylidene]-propane-1,3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50011148 ((Z)-4-(6-Amino-purin-9-yl)-but-2-en-1-ol | 4-(6-Am...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023885 (4-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-but-2-yn-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023886 (2-[2-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-ethylide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 166 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023887 (4-(6-Amino-purin-9-yl)-2-methyl-but-2-en-1-ol | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023882 (5-(6-Amino-purin-9-yl)-pent-3-ene-1,2-diol | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023877 (4-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-but-2-en-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50011180 (4-(6-Amino-purin-9-yl)-but-2-en-1-ol | CHEMBL49917) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50023884 (4-(6-Amino-purin-9-yl)-2-methyl-but-2-en-1-ol | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50367765 (CHEMBL1794978) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase | J Med Chem 31: 1729-38 (1988) BindingDB Entry DOI: 10.7270/Q2HM5920 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50026329 (3-(7-Amino-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against S-adenosyl-homocysteine hydrolase | J Med Chem 28: 471-7 (1985) BindingDB Entry DOI: 10.7270/Q21C1XF3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50140282 (1-{4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172695 (CHEMBL370103 | {2-[3-((4R,5R)-3,3-Dibutyl-7-dimeth...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172649 (1-{5-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172702 (4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hydrox...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50370667 (CHEMBL555246) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172668 (1-{4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172709 (1-{4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50134416 (CHEMBL332974 | Trifluoro-acetate{4-[3-((8R,9R)-7,7...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description In vitro inhibitory activity against uptake of [14C]-taurocholate in baby hamster kidney cells transfected with cDNA from human Apical Sodium-Codepen... | Bioorg Med Chem Lett 13: 3727-30 (2003) BindingDB Entry DOI: 10.7270/Q2M044T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50370669 (CHEMBL555022) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50370670 (CHEMBL540126) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172608 ((4R,5R)-3,3-Dibutyl-7-dimethylamino-9-methoxy-5-(4...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBAT | J Med Chem 48: 5837-52 (2005) Article DOI: 10.1021/jm040215+ BindingDB Entry DOI: 10.7270/Q26M37MS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-Hydroxyacid oxidase 1 (Homo sapiens (Human)) | BDBM560934 (5-(3- (benzo[d][1,3]dioxol- 5-yl)phenoxy)-1H- 1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy... | Citation and Details BindingDB Entry DOI: 10.7270/Q2D221VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172652 ((4R,5R)-5-(3-Amino-phenyl)-3,3-dibutyl-7-dimethyla...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172667 (4-[3-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hydrox...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172681 ((Carboxymethyl-{4-[4-((4R,5R)-3,3-dibutyl-7-dimeth...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172661 ((4R,5R)-3,3-Dibutyl-7-dimethylamino-5-(4-hydroxy-p...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172690 ((Carboxymethyl-{5-[4-((4R,5R)-3,3-dibutyl-7-dimeth...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50370665 (CHEMBL555024) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBAT | J Med Chem 48: 5837-52 (2005) Article DOI: 10.1021/jm040215+ BindingDB Entry DOI: 10.7270/Q26M37MS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-Hydroxyacid oxidase 1 (Homo sapiens (Human)) | BDBM560931 (5-((3',5'-dichloro-[1,1'- biphenyl]-3-yl)oxy)- 1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy... | Citation and Details BindingDB Entry DOI: 10.7270/Q2D221VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172675 (1-[2-(2-{2-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50370665 (CHEMBL555024) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50134424 (CHEMBL332973 | [2-(2-{2-[4-((8R,9R)-7,7-Dibutyl-2-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description In vitro inhibitory activity against uptake of [14C]-taurocholate in baby hamster kidney cells transfected with cDNA from human Apical Sodium-Codepen... | Bioorg Med Chem Lett 13: 3727-30 (2003) BindingDB Entry DOI: 10.7270/Q2M044T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172700 ((4R,5R)-3,3-Dibutyl-7-dimethylamino-5-(3-fluoro-4-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172680 (CHEMBL426152 | [3-((2R,3R)-3,3-Dibutyl-7-dimethyla...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172688 (CHEMBL194420 | [2-(2-{2-[4-((4R,5R)-3,3-Dibutyl-7-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-Hydroxyacid oxidase 1 (Homo sapiens (Human)) | BDBM560926 (5-(4-ethynylphenoxy)- 1H-1,2,3-triazole-4- carboxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy... | Citation and Details BindingDB Entry DOI: 10.7270/Q2D221VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-Hydroxyacid oxidase 1 (Homo sapiens (Human)) | BDBM560933 (5-(4- (benzo[d][1,3]dioxol- 5-yl)phenoxy)-1H- 1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy... | Citation and Details BindingDB Entry DOI: 10.7270/Q2D221VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172706 (1-[2-(2-{2-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172650 ((Carboxymethyl-{6-[4-((4R,5R)-3,3-dibutyl-7-dimeth...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172653 (1-{3-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172671 ((4R,5R)-3,3-Dibutyl-7-dimethylamino-5-(3-hydroxyme...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ileal sodium/bile acid cotransporter (Homo sapiens (Human)) | BDBM50172701 ((4R,5R)-3,3-Dibutyl-7-dimethylamino-1,1-dioxo-5-th...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT | J Med Chem 48: 5853-68 (2005) Article DOI: 10.1021/jm0402162 BindingDB Entry DOI: 10.7270/Q22V2GW2 | |||||||||||
More data for this Ligand-Target Pair |
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