Compile Data Set for Download or QSAR

Found 98 hits with Last Name = 'kelley' and Initial = 'jl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042365 (CHEMBL117417 | [3-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3cccc(CSCP(O)(O)=O)c3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H16N5O4PS/c15-14-17-12-11(13(20)18-14)16-7-19(12)5-9-2-1-3-10(4-9)6-25-8-24(21,22)23/h1-4,7H,5-6,8H2,(H2,21,22,23)(H3,15,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033660 (CHEMBL269745 | {[5-(2-Amino-6-oxo-1,6-dihydro-puri...) Show SMILES Nc1nc2n(CCCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C11H19N5O6P2/c12-11-14-9-8(10(17)15-11)13-6-16(9)4-2-1-3-5-23(18,19)7-24(20,21)22/h6H,1-5,7H2,(H,18,19)(H2,20,21,22)(H3,12,14,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033663 (CHEMBL7319 | {[6-(2-Amino-6-oxo-1,6-dihydro-purin-...) Show SMILES Nc1nc2n(CCCCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H21N5O6P2/c13-12-15-10-9(11(18)16-12)14-7-17(10)5-3-1-2-4-6-24(19,20)8-25(21,22)23/h7H,1-6,8H2,(H,19,20)(H2,21,22,23)(H3,13,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033666 (2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methox...) Show SMILES Nc1nc2n(COCCOP(O)(=O)OP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C8H13N5O9P2/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-20-1-2-21-24(18,19)22-23(15,16)17/h3H,1-2,4H2,(H,18,19)(H2,15,16,17)(H3,9,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033666 (2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methox...) Show SMILES Nc1nc2n(COCCOP(O)(=O)OP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C8H13N5O9P2/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-20-1-2-21-24(18,19)22-23(15,16)17/h3H,1-2,4H2,(H,18,19)(H2,15,16,17)(H3,9,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042370 (CHEMBL326595 | [3-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3cccc(COCP(O)(O)=O)c3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H16N5O5P/c15-14-17-12-11(13(20)18-14)16-7-19(12)5-9-2-1-3-10(4-9)6-24-8-25(21,22)23/h1-4,7H,5-6,8H2,(H2,21,22,23)(H3,15,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042364 (CHEMBL327010 | [2-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3ccccc3OCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H14N5O5P/c14-13-16-11-10(12(19)17-13)15-6-18(11)5-8-3-1-2-4-9(8)23-7-24(20,21)22/h1-4,6H,5,7H2,(H2,20,21,22)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033661 (CHEMBL7247 | {[7-(2-Amino-6-oxo-1,6-dihydro-purin-...) Show SMILES Nc1nc2n(CCCCCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H23N5O6P2/c14-13-16-11-10(12(19)17-13)15-8-18(11)6-4-2-1-3-5-7-25(20,21)9-26(22,23)24/h8H,1-7,9H2,(H,20,21)(H2,22,23,24)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033666 (2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methox...) Show SMILES Nc1nc2n(COCCOP(O)(=O)OP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C8H13N5O9P2/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-20-1-2-21-24(18,19)22-23(15,16)17/h3H,1-2,4H2,(H,18,19)(H2,15,16,17)(H3,9,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042372 (CHEMBL117127 | {3-[3-(2-Amino-6-oxo-1,6-dihydro-pu...) Show SMILES Nc1nc2n(Cc3cccc(CCCP(O)(O)=O)c3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C15H18N5O4P/c16-15-18-13-12(14(21)19-15)17-9-20(13)8-11-4-1-3-10(7-11)5-2-6-25(22,23)24/h1,3-4,7,9H,2,5-6,8H2,(H2,22,23,24)(H3,16,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042363 (CHEMBL333946 | {2-[2-(2-Amino-6-oxo-1,6-dihydro-pu...) Show SMILES Nc1nc2n(Cc3ccccc3CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H16N5O4P/c15-14-17-12-11(13(20)18-14)16-8-19(12)7-10-4-2-1-3-9(10)5-6-24(21,22)23/h1-4,8H,5-7H2,(H2,21,22,23)(H3,15,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042367 (CHEMBL325716 | {3-[3-(2-Amino-6-oxo-1,6-dihydro-pu...) Show SMILES Nc1nc2n(Cc3cccc(C=CCP(O)(O)=O)c3)cnc2c(=O)[nH]1 |w:12.12| Show InChI InChI=1S/C15H16N5O4P/c16-15-18-13-12(14(21)19-15)17-9-20(13)8-11-4-1-3-10(7-11)5-2-6-25(22,23)24/h1-5,7,9H,6,8H2,(H2,22,23,24)(H3,16,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042369 (CHEMBL119243 | {2-[3-(2-Amino-6-oxo-1,6-dihydro-pu...) Show SMILES Nc1nc2n(Cc3cccc(COCCP(O)(O)=O)c3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C15H18N5O5P/c16-15-18-13-12(14(21)19-15)17-9-20(13)7-10-2-1-3-11(6-10)8-25-4-5-26(22,23)24/h1-3,6,9H,4-5,7-8H2,(H2,22,23,24)(H3,16,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033664 (CHEMBL7068 | {[4-(2-Amino-6-oxo-1,6-dihydro-purin-...) Show SMILES Nc1nc2n(CCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H17N5O6P2/c11-10-13-8-7(9(16)14-10)12-5-15(8)3-1-2-4-22(17,18)6-23(19,20)21/h5H,1-4,6H2,(H,17,18)(H2,19,20,21)(H3,11,13,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042362 (CHEMBL331133 | [2-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3ccccc3COCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H16N5O5P/c15-14-17-12-11(13(20)18-14)16-7-19(12)5-9-3-1-2-4-10(9)6-24-8-25(21,22)23/h1-4,7H,5-6,8H2,(H2,21,22,23)(H3,15,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033663 (CHEMBL7319 | {[6-(2-Amino-6-oxo-1,6-dihydro-purin-...) Show SMILES Nc1nc2n(CCCCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H21N5O6P2/c13-12-15-10-9(11(18)16-12)14-7-17(10)5-3-1-2-4-6-24(19,20)8-25(21,22)23/h7H,1-6,8H2,(H,19,20)(H2,21,22,23)(H3,13,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042366 (CHEMBL116580 | [3-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3cccc(OCP(O)(O)=O)c3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H14N5O5P/c14-13-16-11-10(12(19)17-13)15-6-18(11)5-8-2-1-3-9(4-8)23-7-24(20,21)22/h1-4,6H,5,7H2,(H2,20,21,22)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033660 (CHEMBL269745 | {[5-(2-Amino-6-oxo-1,6-dihydro-puri...) Show SMILES Nc1nc2n(CCCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C11H19N5O6P2/c12-11-14-9-8(10(17)15-11)13-6-16(9)4-2-1-3-5-23(18,19)7-24(20,21)22/h6H,1-5,7H2,(H,18,19)(H2,20,21,22)(H3,12,14,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042361 (CHEMBL324839 | {3-[2-(2-Amino-6-oxo-1,6-dihydro-pu...) Show SMILES Nc1nc2n(Cc3ccccc3OCCCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C15H18N5O5P/c16-15-18-13-12(14(21)19-15)17-9-20(13)8-10-4-1-2-5-11(10)25-6-3-7-26(22,23)24/h1-2,4-5,9H,3,6-8H2,(H2,22,23,24)(H3,16,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033661 (CHEMBL7247 | {[7-(2-Amino-6-oxo-1,6-dihydro-purin-...) Show SMILES Nc1nc2n(CCCCCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H23N5O6P2/c14-13-16-11-10(12(19)17-13)15-8-18(11)6-4-2-1-3-5-7-25(20,21)9-26(22,23)24/h8H,1-7,9H2,(H,20,21)(H2,22,23,24)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033665 (CHEMBL268378 | {[5-(2-Amino-6-oxo-1,6-dihydro-puri...) Show SMILES CCOP(O)(=O)CP(O)(=O)CCCCCn1cnc2c1nc(N)[nH]c2=O Show InChI InChI=1S/C13H23N5O6P2/c1-2-24-26(22,23)9-25(20,21)7-5-3-4-6-18-8-15-10-11(18)16-13(14)17-12(10)19/h8H,2-7,9H2,1H3,(H,20,21)(H,22,23)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033664 (CHEMBL7068 | {[4-(2-Amino-6-oxo-1,6-dihydro-purin-...) Show SMILES Nc1nc2n(CCCCP(O)(=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H17N5O6P2/c11-10-13-8-7(9(16)14-10)12-5-15(8)3-1-2-4-22(17,18)6-23(19,20)21/h5H,1-4,6H2,(H,17,18)(H2,19,20,21)(H3,11,13,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033662 (CHEMBL7194 | {Hydroxy-[5-(2-hydroxy-6-oxo-1,6-dihy...) Show SMILES OP(O)(=O)CP(O)(=O)CCCCCn1cnc2c1[nH]c(=O)[nH]c2=O Show InChI InChI=1S/C11H18N4O7P2/c16-10-8-9(13-11(17)14-10)15(6-12-8)4-2-1-3-5-23(18,19)7-24(20,21)22/h6H,1-5,7H2,(H,18,19)(H2,20,21,22)(H2,13,14,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chloride				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Histidine decarboxylase (Rattus norvegicus)	BDBM50010139 (CHEMBL54664 | L-Histidine Methyl Ester) Show SMILES COC(=O)[C@@H](N)Cc1c[nH]cn1 |r| Show InChI InChI=1S/C7H11N3O2/c1-12-7(11)6(8)2-5-3-9-4-10-5/h3-4,6H,2,8H2,1H3,(H,9,10)/t6-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production using L-histidine-carboxyl-14C as substr...				J Med Chem 20: 506-9 (1977) BindingDB Entry DOI: 10.7270/Q2FN17QW
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042360 (CHEMBL117588 | [4-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3ccc(COCP(O)(O)=O)cc3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H16N5O5P/c15-14-17-12-11(13(20)18-14)16-7-19(12)5-9-1-3-10(4-2-9)6-24-8-25(21,22)23/h1-4,7H,5-6,8H2,(H2,21,22,23)(H3,15,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042368 (CHEMBL446671 | [4-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3ccc(cc3)P(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H12N5O4P/c13-12-15-10-9(11(18)16-12)14-6-17(10)5-7-1-3-8(4-2-7)22(19,20)21/h1-4,6H,5H2,(H2,19,20,21)(H3,13,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033665 (CHEMBL268378 | {[5-(2-Amino-6-oxo-1,6-dihydro-puri...) Show SMILES CCOP(O)(=O)CP(O)(=O)CCCCCn1cnc2c1nc(N)[nH]c2=O Show InChI InChI=1S/C13H23N5O6P2/c1-2-24-26(22,23)9-25(20,21)7-5-3-4-6-18-8-15-10-11(18)16-13(14)17-12(10)19/h8H,2-7,9H2,1H3,(H,20,21)(H,22,23)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50033662 (CHEMBL7194 | {Hydroxy-[5-(2-hydroxy-6-oxo-1,6-dihy...) Show SMILES OP(O)(=O)CP(O)(=O)CCCCCn1cnc2c1[nH]c(=O)[nH]c2=O Show InChI InChI=1S/C11H18N4O7P2/c16-10-8-9(13-11(17)14-10)15(6-12-8)4-2-1-3-5-23(18,19)7-24(20,21)22/h6H,1-5,7H2,(H,18,19)(H2,20,21,22)(H2,13,14,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of ethylenediaminetetraacetic acid (Na2 EDTA)				J Med Chem 38: 1005-14 (1995) BindingDB Entry DOI: 10.7270/Q2FF3RDR
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50042371 (CHEMBL327003 | [4-(2-Amino-6-oxo-1,6-dihydro-purin...) Show SMILES Nc1nc2n(Cc3ccc(OCP(O)(O)=O)cc3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H14N5O5P/c14-13-16-11-10(12(19)17-13)15-6-18(11)5-8-1-3-9(4-2-8)23-7-24(20,21)22/h1-4,6H,5,7H2,(H2,20,21,22)(H3,14,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assay				J Med Chem 36: 3455-63 (1993) BindingDB Entry DOI: 10.7270/Q2PR7V1V
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007518 ((S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)me...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC Show InChI InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Tested in vitro for inhibition of [3H]spiperone binding to dopamine receptor D2				J Med Chem 36: 3417-23 (1993) BindingDB Entry DOI: 10.7270/Q2S75GZD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007534 (3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hy...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC Show InChI InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Tested in vitro for inhibition of [3H]spiperone binding to dopamine receptor D2				J Med Chem 36: 3417-23 (1993) BindingDB Entry DOI: 10.7270/Q2S75GZD
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030972 (5-(3-sec-Butoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)...) Show SMILES CCC(C)Oc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C18H24N2O5/c1-3-13(2)25-16-6-4-5-14(10-16)9-15-11-20(12-24-8-7-21)18(23)19-17(15)22/h4-6,10-11,13,21H,3,7-9,12H2,1-2H3,(H,19,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50031005 (1-(2-Hydroxy-ethoxymethyl)-5-(3-propoxy-benzyl)-1H...) Show SMILES CCCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C17H22N2O5/c1-2-7-24-15-5-3-4-13(10-15)9-14-11-19(12-23-8-6-20)17(22)18-16(14)21/h3-5,10-11,20H,2,6-9,12H2,1H3,(H,18,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030974 (1-(2-Hydroxy-1-hydroxymethyl-ethoxymethyl)-5-(3-pr...) Show SMILES CCCOc1cccc(Cc2cn(COC(CO)CO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C18H24N2O6/c1-2-6-25-15-5-3-4-13(8-15)7-14-9-20(18(24)19-17(14)23)12-26-16(10-21)11-22/h3-5,8-9,16,21-22H,2,6-7,10-12H2,1H3,(H,19,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50031009 (1-(2-Hydroxy-ethoxymethyl)-5-(3-isobutoxy-benzyl)-...) Show SMILES CC(C)COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C18H24N2O5/c1-13(2)11-25-16-5-3-4-14(9-16)8-15-10-20(12-24-7-6-21)18(23)19-17(15)22/h3-5,9-10,13,21H,6-8,11-12H2,1-2H3,(H,19,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030990 (5-[3-(3-Fluoro-propoxy)-benzyl]-1-(2-hydroxy-ethox...) Show SMILES OCCOCn1cc(Cc2cccc(OCCCF)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H21FN2O5/c18-5-2-7-25-15-4-1-3-13(10-15)9-14-11-20(12-24-8-6-21)17(23)19-16(14)22/h1,3-4,10-11,21H,2,5-9,12H2,(H,19,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030980 (1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL...) Show SMILES OCCOCn1cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C21H22N2O5/c24-9-10-27-15-23-13-18(20(25)22-21(23)26)11-17-7-4-8-19(12-17)28-14-16-5-2-1-3-6-16/h1-8,12-13,24H,9-11,14-15H2,(H,22,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50031006 (5-(3-Ethoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...) Show SMILES CCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C16H20N2O5/c1-2-23-14-5-3-4-12(9-14)8-13-10-18(11-22-7-6-19)16(21)17-15(13)20/h3-5,9-10,19H,2,6-8,11H2,1H3,(H,17,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50031007 (5-[3-(3-Fluoro-propoxy)-benzyl]-1-(2-hydroxy-1-hyd...) Show SMILES OCC(CO)OCn1cc(Cc2cccc(OCCCF)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C18H23FN2O6/c19-5-2-6-26-15-4-1-3-13(8-15)7-14-9-21(18(25)20-17(14)24)12-27-16(10-22)11-23/h1,3-4,8-9,16,22-23H,2,5-7,10-12H2,(H,20,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030999 (5-(3-Chloro-benzyl)-1-(2-hydroxy-1-hydroxymethyl-e...) Show SMILES OCC(CO)OCn1cc(Cc2cccc(Cl)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C15H17ClN2O5/c16-12-3-1-2-10(5-12)4-11-6-18(15(22)17-14(11)21)9-23-13(7-19)8-20/h1-3,5-6,13,19-20H,4,7-9H2,(H,17,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030983 (5-(3-Allyloxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1...) Show SMILES OCCOCn1cc(Cc2cccc(OCC=C)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H20N2O5/c1-2-7-24-15-5-3-4-13(10-15)9-14-11-19(12-23-8-6-20)17(22)18-16(14)21/h2-5,10-11,20H,1,6-9,12H2,(H,18,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50031004 (1-(2-Hydroxy-ethoxymethyl)-5-(3-isopropoxy-benzyl)...) Show SMILES CC(C)Oc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C17H22N2O5/c1-12(2)24-15-5-3-4-13(9-15)8-14-10-19(11-23-7-6-20)17(22)18-16(14)21/h3-5,9-10,12,20H,6-8,11H2,1-2H3,(H,18,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030995 (5-(3-Butoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...) Show SMILES CCCCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C18H24N2O5/c1-2-3-8-25-16-6-4-5-14(11-16)10-15-12-20(13-24-9-7-21)18(23)19-17(15)22/h4-6,11-12,21H,2-3,7-10,13H2,1H3,(H,19,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50122955 (2-(4,6-Difluoro-indan-1-ylidene)-acetamide | CHEMB...) Show SMILES NC(=O)\C=C1/CCc2c1cc(F)cc2F Show InChI InChI=1S/C11H9F2NO/c12-7-4-9-6(3-11(14)15)1-2-8(9)10(13)5-7/h3-5H,1-2H2,(H2,14,15)/b6-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Monoamine oxidase B (MAO-B)				J Med Chem 46: 399-408 (2003) Article DOI: 10.1021/jm020067s BindingDB Entry DOI: 10.7270/Q2VH5N7F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM11638 (CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...) Show SMILES CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Tested in vitro for inhibition of [3H]spiperone binding to dopamine receptor D2				J Med Chem 36: 3417-23 (1993) BindingDB Entry DOI: 10.7270/Q2S75GZD
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030984 (5-(3-Chloro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...) Show SMILES OCCOCn1cc(Cc2cccc(Cl)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C14H15ClN2O4/c15-12-3-1-2-10(7-12)6-11-8-17(9-21-5-4-18)14(20)16-13(11)19/h1-3,7-8,18H,4-6,9H2,(H,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030981 (5-(3,5-Difluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)...) Show SMILES OCCOCn1cc(Cc2cc(F)cc(F)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C14H14F2N2O4/c15-11-4-9(5-12(16)6-11)3-10-7-18(8-22-2-1-19)14(21)17-13(10)20/h4-7,19H,1-3,8H2,(H,17,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50026387 (1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4...) Show SMILES OCCOCn1cc(Cc2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C14H16N2O4/c17-6-7-20-10-16-9-12(13(18)15-14(16)19)8-11-4-2-1-3-5-11/h1-5,9,17H,6-8,10H2,(H,15,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Uridine phosphorylase 1 (Mus musculus)	BDBM50030976 (5-(3-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...) Show SMILES OCCOCn1cc(Cc2cccc(F)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C14H15FN2O4/c15-12-3-1-2-10(7-12)6-11-8-17(9-21-5-4-18)14(20)16-13(11)19/h1-3,7-8,18H,4-6,9H2,(H,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50005520 ((S)-2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimid...) Show SMILES Nc1nc(N)c(CCCNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)c(=O)[nH]1 Show InChI InChI=1S/C19H24N6O6/c20-15-12(17(29)25-19(21)24-15)2-1-9-22-11-5-3-10(4-6-11)16(28)23-13(18(30)31)7-8-14(26)27/h3-6,13,22H,1-2,7-9H2,(H,23,28)(H,26,27)(H,30,31)(H5,20,21,24,25,29)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against hog liver				J Med Chem 33: 561-7 (1990) BindingDB Entry DOI: 10.7270/Q2XW4HS0
					More data for this Ligand-Target Pair

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