Compile Data Set for Download or QSAR

Found 67 hits with Last Name = 'luzikov' and Initial = 'yn'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058033 (CHEMBL3330787) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2sccc12 Show InChI InChI=1S/C22H24N6O2S.ClH/c1-25-7-8-26-17-14-6-11-31-21(14)18(27-9-10-28-22(23)24)16-15(17)19(29)12-4-2-3-5-13(12)20(16)30;/h2-6,11,25-27H,7-10H2,1H3,(H4,23,24,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058035 (CHEMBL3330789) Show SMILES Cl.NCCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C22H24N6O2S.ClH/c23-7-3-8-26-18-16-15(19(29)12-4-1-2-5-13(12)20(16)30)17(14-6-11-31-21(14)18)27-9-10-28-22(24)25;/h1-2,4-6,11,26-27H,3,7-10,23H2,(H4,24,25,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058037 (CHEMBL3330791) Show SMILES Cl.NC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2sccc12 Show InChI InChI=1S/C22H24N8O2S.ClH/c23-21(24)29-8-6-27-16-13-5-10-33-20(13)17(28-7-9-30-22(25)26)15-14(16)18(31)11-3-1-2-4-12(11)19(15)32;/h1-5,10,27-28H,6-9H2,(H4,23,24,29)(H4,25,26,30);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058034 (CHEMBL3330788) Show SMILES Cl.NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C21H22N6O2S.ClH/c22-6-7-25-17-15-14(18(28)11-3-1-2-4-12(11)19(15)29)16(13-5-10-30-20(13)17)26-8-9-27-21(23)24;/h1-5,10,25-26H,6-9,22H2,(H4,23,24,27);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058029 (CHEMBL3330786) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C22H24N6O2S.ClH/c1-25-7-8-27-18-16-15(19(29)12-4-2-3-5-13(12)20(16)30)17(14-6-11-31-21(14)18)26-9-10-28-22(23)24;/h2-6,11,25-27H,7-10H2,1H3,(H4,23,24,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058038 (CHEMBL3359606) Show SMILES Cl.CC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(C)=N)c2sccc12 Show InChI InChI=1S/C24H26N6O2S.ClH/c1-13(25)27-8-10-29-20-17-7-12-33-24(17)21(30-11-9-28-14(2)26)19-18(20)22(31)15-5-3-4-6-16(15)23(19)32;/h3-7,12,29-30H,8-11H2,1-2H3,(H2,25,27)(H2,26,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058038 (CHEMBL3359606) Show SMILES Cl.CC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(C)=N)c2sccc12 Show InChI InChI=1S/C24H26N6O2S.ClH/c1-13(25)27-8-10-29-20-17-7-12-33-24(17)21(30-11-9-28-14(2)26)19-18(20)22(31)15-5-3-4-6-16(15)23(19)32;/h3-7,12,29-30H,8-11H2,1-2H3,(H2,25,27)(H2,26,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058036 (CHEMBL3330790) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC)c2sccc12 Show InChI InChI=1S/C22H24N4O2S.ClH/c1-23-8-10-25-18-15-7-12-29-22(15)19(26-11-9-24-2)17-16(18)20(27)13-5-3-4-6-14(13)21(17)28;/h3-7,12,23-26H,8-11H2,1-2H3;1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058030 (CHEMBL3330785) Show SMILES Cl.NC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(N)c2ccsc12 Show InChI InChI=1S/C19H17N5O2S.ClH/c20-14-11-5-8-27-18(11)15(23-6-7-24-19(21)22)13-12(14)16(25)9-3-1-2-4-10(9)17(13)26;/h1-5,8,23H,6-7,20H2,(H4,21,22,24);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058029 (CHEMBL3330786) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C22H24N6O2S.ClH/c1-25-7-8-27-18-16-15(19(29)12-4-2-3-5-13(12)20(16)30)17(14-6-11-31-21(14)18)26-9-10-28-22(23)24;/h2-6,11,25-27H,7-10H2,1H3,(H4,23,24,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058036 (CHEMBL3330790) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC)c2sccc12 Show InChI InChI=1S/C22H24N4O2S.ClH/c1-23-8-10-25-18-15-7-12-29-22(15)19(26-11-9-24-2)17-16(18)20(27)13-5-3-4-6-14(13)21(17)28;/h3-7,12,23-26H,8-11H2,1-2H3;1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058035 (CHEMBL3330789) Show SMILES Cl.NCCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C22H24N6O2S.ClH/c23-7-3-8-26-18-16-15(19(29)12-4-1-2-5-13(12)20(16)30)17(14-6-11-31-21(14)18)27-9-10-28-22(24)25;/h1-2,4-6,11,26-27H,3,7-10,23H2,(H4,24,25,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058037 (CHEMBL3330791) Show SMILES Cl.NC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2sccc12 Show InChI InChI=1S/C22H24N8O2S.ClH/c23-21(24)29-8-6-27-16-13-5-10-33-20(13)17(28-7-9-30-22(25)26)15-14(16)18(31)11-3-1-2-4-12(11)19(15)32;/h1-5,10,27-28H,6-9H2,(H4,23,24,29)(H4,25,26,30);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058034 (CHEMBL3330788) Show SMILES Cl.NCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2ccsc12 Show InChI InChI=1S/C21H22N6O2S.ClH/c22-6-7-25-17-15-14(18(28)11-3-1-2-4-12(11)19(15)29)16(13-5-10-30-20(13)17)26-8-9-27-21(23)24;/h1-5,10,25-26H,6-9,22H2,(H4,23,24,27);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058031 (CHEMBL3330784) Show SMILES Cl.NC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(N)c2sccc12 Show InChI InChI=1S/C19H17N5O2S.ClH/c20-14-12-13(17(26)10-4-2-1-3-9(10)16(12)25)15(11-5-8-27-18(11)14)23-6-7-24-19(21)22;/h1-5,8,23H,6-7,20H2,(H4,21,22,24);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058033 (CHEMBL3330787) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC(N)=N)c2sccc12 Show InChI InChI=1S/C22H24N6O2S.ClH/c1-25-7-8-26-17-14-6-11-31-21(14)18(27-9-10-28-22(23)24)16-15(17)19(29)12-4-2-3-5-13(12)20(16)30;/h2-6,11,25-27H,7-10H2,1H3,(H4,23,24,28);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058031 (CHEMBL3330784) Show SMILES Cl.NC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(N)c2sccc12 Show InChI InChI=1S/C19H17N5O2S.ClH/c20-14-12-13(17(26)10-4-2-1-3-9(10)16(12)25)15(11-5-8-27-18(11)14)23-6-7-24-19(21)22;/h1-5,8,23H,6-7,20H2,(H4,21,22,24);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50246815 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES N=C(Nc1ccccc1)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:17| Show InChI InChI=1S/C30H25N5O2S/c31-30(32-21-10-2-1-3-11-21)38-17-7-15-34-28(36)26-27(29(34)37)35-23-13-5-4-8-20(23)18-24(35)22-12-6-9-19-14-16-33(26)25(19)22/h1-6,8-14,16,24H,7,15,17-18H2,(H2,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human IGF1R				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human EPHB4				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human INSR				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK4/CycD1				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058030 (CHEMBL3330785) Show SMILES Cl.NC(=N)NCCNc1c2C(=O)c3ccccc3C(=O)c2c(N)c2ccsc12 Show InChI InChI=1S/C19H17N5O2S.ClH/c20-14-11-5-8-27-18(11)15(23-6-7-24-19(21)22)13-12(14)16(25)9-3-1-2-4-10(9)17(13)26;/h1-5,8,23H,6-7,20H2,(H4,21,22,24);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human MET				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK2/Cyc2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human SRC				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50246776 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES CN=C(N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O |w:1.0| Show InChI InChI=1S/C25H21N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,14H,5,11,13H2,1H3,(H2,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human EPHB4				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human IGF1R				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human PDGFRbeta				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50246730 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES NC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:10| Show InChI InChI=1S/C24H21N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,18H,4,10,12-13H2,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK2/Cyc2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50246815 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES N=C(Nc1ccccc1)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:17| Show InChI InChI=1S/C30H25N5O2S/c31-30(32-21-10-2-1-3-11-21)38-17-7-15-34-28(36)26-27(29(34)37)35-23-13-5-4-8-20(23)18-24(35)22-12-6-9-19-14-16-33(26)25(19)22/h1-6,8-14,16,24H,7,15,17-18H2,(H2,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human AXL				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human FAK				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human EGFR				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50246774 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O Show InChI InChI=1S/C24H19N5O2S/c25-24(26)32-12-4-10-28-22(30)20-21(23(28)31)29-17-8-2-1-5-15(17)13-18(29)16-7-3-6-14-9-11-27(20)19(14)16/h1-3,5-9,11,13H,4,10,12H2,(H3,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human VEGFR3				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of full length human N-terminal GST-HIS6-tagged Aurora B expressed in sf9 cells by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Aurora kinase C (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of full length human N-terminal GST-HIS6-tagged Aurora C expressed in sf9 cells by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human MAP3K7 by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human MKNK1 by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of full length human N-terminal GST-HIS6-tagged PIM1 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of full length human N-terminal GST-HIS6-tagged PIM3 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Dual serine/threonine and tyrosine protein kinase (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human RIPK5 by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase tousled-like 1 (Homo sapiens (Human))	BDBM50154291 (CHEMBL3775181) Show SMILES CS(O)(=O)=O.Cc1oc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c2c1C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C22H18N2O6.CH4O3S/c1-9-13(22(29)24-7-6-10(23)8-24)16-19(27)14-15(20(28)21(16)30-9)18(26)12-5-3-2-4-11(12)17(14)25;1-5(2,3)4/h2-5,10,27-28H,6-8,23H2,1H3;1H3,(H,2,3,4)/t10-;/m0./s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Russia; Mendeleyev University of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human N-terminal FLAG, C-terminal HIS8-tagged TLK1 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assay				Eur J Med Chem 112: 114-29 (2016) Article DOI: 10.1016/j.ejmech.2016.01.050 BindingDB Entry DOI: 10.7270/Q2VQ34K1
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50246732 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human INSR				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50246815 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES N=C(Nc1ccccc1)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:17| Show InChI InChI=1S/C30H25N5O2S/c31-30(32-21-10-2-1-3-11-21)38-17-7-15-34-28(36)26-27(29(34)37)35-23-13-5-4-8-20(23)18-24(35)22-12-6-9-19-14-16-33(26)25(19)22/h1-6,8-14,16,24H,7,15,17-18H2,(H2,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK2/Cyc2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50246732 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK2/Cyc2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50246732 (3-(1,3-Dioxo-1,3,9b,10-tetrahydro-2H-indolo[1',7':...) Show SMILES CNC(=N)SCCCN1C(=O)C2=C(C1=O)n1ccc3cccc(C4Cc5ccccc5N24)c13 |c:11| Show InChI InChI=1S/C25H23N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,19H,5,11,13-14H2,1H3,(H2,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK4/CycD1				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50246776 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES CN=C(N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O |w:1.0| Show InChI InChI=1S/C25H21N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,14H,5,11,13H2,1H3,(H2,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK4/CycD1				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50246776 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES CN=C(N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O |w:1.0| Show InChI InChI=1S/C25H21N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,14H,5,11,13H2,1H3,(H2,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human CDK2/Cyc2				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50246776 (3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...) Show SMILES CN=C(N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O |w:1.0| Show InChI InChI=1S/C25H21N5O2S/c1-27-25(26)33-13-5-11-29-23(31)21-22(24(29)32)30-18-9-3-2-6-16(18)14-19(30)17-8-4-7-15-10-12-28(21)20(15)17/h2-4,6-10,12,14H,5,11,13H2,1H3,(H2,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of General Genetics Curated by ChEMBL					Assay Description Inhibition of human INSR				J Med Chem 51: 7731-6 (2008) Article DOI: 10.1021/jm800758s BindingDB Entry DOI: 10.7270/Q2HD7VH4
					More data for this Ligand-Target Pair

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