Compile Data Set for Download or QSAR

Found 220 hits with Last Name = 'nienaber' and Initial = 'vl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157087 (6-(2-Phenyl-cyclopropyl)-8-(pyrimidin-2-ylamino)-n...) Show SMILES NC(=N)c1ccc2cc(cc(Nc3ncccn3)c2c1)C1CC1c1ccccc1 Show InChI InChI=1S/C24H21N5/c25-23(26)17-8-7-16-11-18(20-14-19(20)15-5-2-1-3-6-15)13-22(21(16)12-17)29-24-27-9-4-10-28-24/h1-13,19-20H,14H2,(H3,25,26)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138673 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-e...) Show SMILES CCC1CNCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 Show InChI InChI=1S/C23H24N4O/c1-2-14-12-26-13-19-7-8-20(11-21(14)19)27-23(28)18-6-4-15-9-17(22(24)25)5-3-16(15)10-18/h3-11,14,26H,2,12-13H2,1H3,(H3,24,25)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157094 (8-(Pyrimidin-2-ylamino)-6-((E)-styryl)-naphthalene...) Show SMILES NC(=N)c1ccc2cc(\C=C\c3ccccc3)cc(Nc3ncccn3)c2c1 Show InChI InChI=1S/C23H19N5/c24-22(25)19-10-9-18-13-17(8-7-16-5-2-1-3-6-16)14-21(20(18)15-19)28-23-26-11-4-12-27-23/h1-15H,(H3,24,25)(H,26,27,28)/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138661 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3,5...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC(C)C)c1 Show InChI InChI=1S/C24H27N3O3/c1-14(2)29-21-11-20(12-22(13-21)30-15(3)4)27-24(28)19-8-6-16-9-18(23(25)26)7-5-17(16)10-19/h5-15H,1-4H3,(H3,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138656 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1,2...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CNCCc2c1 Show InChI InChI=1S/C21H20N4O/c22-20(23)16-3-1-14-10-17(4-2-13(14)9-16)21(26)25-19-6-5-18-12-24-8-7-15(18)11-19/h1-6,9-11,24H,7-8,12H2,(H3,22,23)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138665 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...) Show SMILES CC(C)C1NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 Show InChI InChI=1S/C24H26N4O/c1-14(2)22-21-13-20(8-7-15(21)9-10-27-22)28-24(29)19-6-4-16-11-18(23(25)26)5-3-17(16)12-19/h3-8,11-14,22,27H,9-10H2,1-2H3,(H3,25,26)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	23.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138658 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CCNC(C3CCCC3)c2c1 Show InChI InChI=1S/C26H28N4O/c27-25(28)20-7-5-19-14-21(8-6-18(19)13-20)26(31)30-22-10-9-16-11-12-29-24(23(16)15-22)17-3-1-2-4-17/h5-10,13-15,17,24,29H,1-4,11-12H2,(H3,27,28)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138661 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3,5...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC(C)C)c1 Show InChI InChI=1S/C24H27N3O3/c1-14(2)29-21-11-20(12-22(13-21)30-15(3)4)27-24(28)19-8-6-16-9-18(23(25)26)7-5-17(16)10-19/h5-15H,1-4H3,(H3,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157093 (6-[2-(1-Cyclohexyl-2-methyl-1,2,3,4-tetrahydro-iso...) Show SMILES CN1CCc2ccc(cc2C1C1CCCCC1)C1CC1c1ccc2cc(ccc2c1)C(N)=N Show InChI InChI=1S/C30H35N3/c1-33-14-13-19-7-10-24(17-28(19)29(33)20-5-3-2-4-6-20)27-18-26(27)23-11-8-22-16-25(30(31)32)12-9-21(22)15-23/h7-12,15-17,20,26-27,29H,2-6,13-14,18H2,1H3,(H3,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138674 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1cccc(OC2CCCC2)c1 Show InChI InChI=1S/C23H23N3O2/c24-22(25)17-10-8-16-13-18(11-9-15(16)12-17)23(27)26-19-4-3-7-21(14-19)28-20-5-1-2-6-20/h3-4,7-14,20H,1-2,5-6H2,(H3,24,25)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trypsin (Sus scrofa)	BDBM50157098 (6-[2-((S)-1-Isopropyl-3,4-dihydro-isoquinolin-7-yl...) Show SMILES CC(C)C1=NCCc2ccc(cc12)[C@H]1CC1c1ccc2cc(ccc2c1)C(N)=N |t:3| Show InChI InChI=1S/C26H27N3/c1-15(2)25-24-13-20(6-3-16(24)9-10-29-25)23-14-22(23)19-7-4-18-12-21(26(27)28)8-5-17(18)11-19/h3-8,11-13,15,22-23H,9-10,14H2,1-2H3,(H3,27,28)/t22?,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157093 (6-[2-(1-Cyclohexyl-2-methyl-1,2,3,4-tetrahydro-iso...) Show SMILES CN1CCc2ccc(cc2C1C1CCCCC1)C1CC1c1ccc2cc(ccc2c1)C(N)=N Show InChI InChI=1S/C30H35N3/c1-33-14-13-19-7-10-24(17-28(19)29(33)20-5-3-2-4-6-20)27-18-26(27)23-11-8-22-16-25(30(31)32)12-9-21(22)15-23/h7-12,15-17,20,26-27,29H,2-6,13-14,18H2,1H3,(H3,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138668 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CCN=C(C3CCCC3)c2c1 |t:24| Show InChI InChI=1S/C26H26N4O/c27-25(28)20-7-5-19-14-21(8-6-18(19)13-20)26(31)30-22-10-9-16-11-12-29-24(23(16)15-22)17-3-1-2-4-17/h5-10,13-15,17H,1-4,11-12H2,(H3,27,28)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138666 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-h...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc(CO)cc1 Show InChI InChI=1S/C19H17N3O2/c20-18(21)15-5-3-14-10-16(6-4-13(14)9-15)19(24)22-17-7-1-12(11-23)2-8-17/h1-10,23H,11H2,(H3,20,21)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138658 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CCNC(C3CCCC3)c2c1 Show InChI InChI=1S/C26H28N4O/c27-25(28)20-7-5-19-14-21(8-6-18(19)13-20)26(31)30-22-10-9-16-11-12-29-24(23(16)15-22)17-3-1-2-4-17/h5-10,13-15,17,24,29H,1-4,11-12H2,(H3,27,28)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50147096 (6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...) Show SMILES NC(=N)c1ccc2cc(cc(Nc3ncccn3)c2c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C22H18N6O/c23-20(24)15-8-7-14-11-16(21(29)27-17-5-2-1-3-6-17)13-19(18(14)12-15)28-22-25-9-4-10-26-22/h1-13H,(H3,23,24)(H,27,29)(H,25,26,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138662 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-a...) Show SMILES NCc1ccc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc1 Show InChI InChI=1S/C19H18N4O/c20-11-12-1-7-17(8-2-12)23-19(24)16-6-4-13-9-15(18(21)22)5-3-14(13)10-16/h1-10H,11,20H2,(H3,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine protease 1 (Homo sapiens (Human))	BDBM50138667 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...) Show SMILES CC(C)C1=NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 |t:3| Show InChI InChI=1S/C24H24N4O/c1-14(2)22-21-13-20(8-7-15(21)9-10-27-22)28-24(29)19-6-4-16-11-18(23(25)26)5-3-17(16)12-19/h3-8,11-14H,9-10H2,1-2H3,(H3,25,26)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50157094 (8-(Pyrimidin-2-ylamino)-6-((E)-styryl)-naphthalene...) Show SMILES NC(=N)c1ccc2cc(\C=C\c3ccccc3)cc(Nc3ncccn3)c2c1 Show InChI InChI=1S/C23H19N5/c24-22(25)19-10-9-18-13-17(8-7-16-5-2-1-3-6-16)14-21(20(18)15-19)28-23-26-11-4-12-27-23/h1-15H,(H3,24,25)(H,26,27,28)/b8-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against kallikrein				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138665 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...) Show SMILES CC(C)C1NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 Show InChI InChI=1S/C24H26N4O/c1-14(2)22-21-13-20(8-7-15(21)9-10-27-22)28-24(29)19-6-4-16-11-18(23(25)26)5-3-17(16)12-19/h3-8,11-14,22,27H,9-10H2,1-2H3,(H3,25,26)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50147088 (6-Carbamimidoyl-4-furan-3-yl-naphthalene-2-carboxy...) Show SMILES NC(=N)c1ccc2cc(cc(-c3ccoc3)c2c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C22H17N3O2/c23-21(24)15-7-6-14-10-17(22(26)25-18-4-2-1-3-5-18)12-20(19(14)11-15)16-8-9-27-13-16/h1-13H,(H3,23,24)(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157090 (6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...) Show SMILES CC(C)C1N(C)CCc2ccc(cc12)C1CC1c1ccc2cc(ccc2c1)C(N)=N Show InChI InChI=1S/C27H31N3/c1-16(2)26-25-14-21(7-4-17(25)10-11-30(26)3)24-15-23(24)20-8-5-19-13-22(27(28)29)9-6-18(19)12-20/h4-9,12-14,16,23-24,26H,10-11,15H2,1-3H3,(H3,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157083 (6-Phenethyl-8-(pyrimidin-2-ylamino)-naphthalene-2-...) Show SMILES NC(=N)c1ccc2cc(CCc3ccccc3)cc(Nc3ncccn3)c2c1 Show InChI InChI=1S/C23H21N5/c24-22(25)19-10-9-18-13-17(8-7-16-5-2-1-3-6-16)14-21(20(18)15-19)28-23-26-11-4-12-27-23/h1-6,9-15H,7-8H2,(H3,24,25)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138667 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...) Show SMILES CC(C)C1=NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 |t:3| Show InChI InChI=1S/C24H24N4O/c1-14(2)22-21-13-20(8-7-15(21)9-10-27-22)28-24(29)19-6-4-16-11-18(23(25)26)5-3-17(16)12-19/h3-8,11-14H,9-10H2,1-2H3,(H3,25,26)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157092 (6-[2-(1-Cyclohexyl-3,4-dihydro-isoquinolin-7-yl)-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C1CC1c1ccc2CCN=C(C3CCCCC3)c2c1 |t:25| Show InChI InChI=1S/C29H31N3/c30-29(31)24-11-8-20-14-22(10-7-21(20)15-24)25-17-26(25)23-9-6-18-12-13-32-28(27(18)16-23)19-4-2-1-3-5-19/h6-11,14-16,19,25-26H,1-5,12-13,17H2,(H3,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138671 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-i...) Show SMILES CC(C)Oc1cccc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)c1 Show InChI InChI=1S/C21H21N3O2/c1-13(2)26-19-5-3-4-18(12-19)24-21(25)17-9-7-14-10-16(20(22)23)8-6-15(14)11-17/h3-13H,1-2H3,(H3,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157096 (6-(2-(1-isopropyl-3,4-dihydroisoquinolin-7-yl)cycl...) Show SMILES CC(C)C1=NCCc2ccc(cc12)C1CC1c1ccc2cc(ccc2c1)C(N)=N |t:3| Show InChI InChI=1S/C26H27N3/c1-15(2)25-24-13-20(6-3-16(24)9-10-29-25)23-14-22(23)19-7-4-18-12-21(26(27)28)8-5-17(18)11-19/h3-8,11-13,15,22-23H,9-10,14H2,1-2H3,(H3,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50157087 (6-(2-Phenyl-cyclopropyl)-8-(pyrimidin-2-ylamino)-n...) Show SMILES NC(=N)c1ccc2cc(cc(Nc3ncccn3)c2c1)C1CC1c1ccccc1 Show InChI InChI=1S/C24H21N5/c25-23(26)17-8-7-16-11-18(20-14-19(20)15-5-2-1-3-6-15)13-22(21(16)12-17)29-24-27-9-4-10-28-24/h1-13,19-20H,14H2,(H3,25,26)(H,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against kallikrein				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157087 (6-(2-Phenyl-cyclopropyl)-8-(pyrimidin-2-ylamino)-n...) Show SMILES NC(=N)c1ccc2cc(cc(Nc3ncccn3)c2c1)C1CC1c1ccccc1 Show InChI InChI=1S/C24H21N5/c25-23(26)17-8-7-16-11-18(20-14-19(20)15-5-2-1-3-6-15)13-22(21(16)12-17)29-24-27-9-4-10-28-24/h1-13,19-20H,14H2,(H3,25,26)(H,27,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138674 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1cccc(OC2CCCC2)c1 Show InChI InChI=1S/C23H23N3O2/c24-22(25)17-10-8-16-13-18(11-9-15(16)12-17)23(27)26-19-4-3-7-21(14-19)28-20-5-1-2-6-20/h3-4,7-14,20H,1-2,5-6H2,(H3,24,25)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138668 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-c...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CCN=C(C3CCCC3)c2c1 |t:24| Show InChI InChI=1S/C26H26N4O/c27-25(28)20-7-5-19-14-21(8-6-18(19)13-20)26(31)30-22-10-9-16-11-12-29-24(23(16)15-22)17-3-1-2-4-17/h5-10,13-15,17H,1-4,11-12H2,(H3,27,28)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138671 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-i...) Show SMILES CC(C)Oc1cccc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)c1 Show InChI InChI=1S/C21H21N3O2/c1-13(2)26-19-5-3-4-18(12-19)24-21(25)17-9-7-14-10-16(20(22)23)8-6-15(14)11-17/h3-13H,1-2H3,(H3,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157099 (4-Bromo-6-carbamimidoyl-naphthalene-2-carboxylic a...) Show SMILES NC(=N)c1ccc2cc(cc(Br)c2c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C18H14BrN3O/c19-16-10-13(18(23)22-14-4-2-1-3-5-14)8-11-6-7-12(17(20)21)9-15(11)16/h1-10H,(H3,20,21)(H,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50157098 (6-[2-((S)-1-Isopropyl-3,4-dihydro-isoquinolin-7-yl...) Show SMILES CC(C)C1=NCCc2ccc(cc12)[C@H]1CC1c1ccc2cc(ccc2c1)C(N)=N |t:3| Show InChI InChI=1S/C26H27N3/c1-15(2)25-24-13-20(6-3-16(24)9-10-29-25)23-14-22(23)19-7-4-18-12-21(26(27)28)8-5-17(18)11-19/h3-8,11-13,15,22-23H,9-10,14H2,1-2H3,(H3,27,28)/t22?,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138679 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-e...) Show SMILES CCOc1cccc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)c1 Show InChI InChI=1S/C20H19N3O2/c1-2-25-18-5-3-4-17(12-18)23-20(24)16-9-7-13-10-15(19(21)22)8-6-14(13)11-16/h3-12H,2H2,1H3,(H3,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138673 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-e...) Show SMILES CCC1CNCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 Show InChI InChI=1S/C23H24N4O/c1-2-14-12-26-13-19-7-8-20(11-21(14)19)27-23(28)18-6-4-15-9-17(22(24)25)5-3-16(15)10-18/h3-11,14,26H,2,12-13H2,1H3,(H3,24,25)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50157084 (8-Furan-3-yl-6-styryl-naphthalene-2-carboxamidine ...) Show SMILES NC(=N)c1ccc2cc(\C=C\c3ccccc3)cc(-c3ccoc3)c2c1 Show InChI InChI=1S/C23H18N2O/c24-23(25)19-9-8-18-12-17(7-6-16-4-2-1-3-5-16)13-21(22(18)14-19)20-10-11-26-15-20/h1-15H,(H3,24,25)/b7-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against kallikrein				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157094 (8-(Pyrimidin-2-ylamino)-6-((E)-styryl)-naphthalene...) Show SMILES NC(=N)c1ccc2cc(\C=C\c3ccccc3)cc(Nc3ncccn3)c2c1 Show InChI InChI=1S/C23H19N5/c24-22(25)19-10-9-18-13-17(8-7-16-5-2-1-3-6-16)14-21(20(18)15-19)28-23-26-11-4-12-27-23/h1-15H,(H3,24,25)(H,26,27,28)/b8-7+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157090 (6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...) Show SMILES CC(C)C1N(C)CCc2ccc(cc12)C1CC1c1ccc2cc(ccc2c1)C(N)=N Show InChI InChI=1S/C27H31N3/c1-16(2)26-25-14-21(7-4-17(25)10-11-30(26)3)24-15-23(24)20-8-5-19-13-22(27(28)29)9-6-18(19)12-20/h4-9,12-14,16,23-24,26H,10-11,15H2,1-3H3,(H3,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50147096 (6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...) Show SMILES NC(=N)c1ccc2cc(cc(Nc3ncccn3)c2c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C22H18N6O/c23-20(24)15-8-7-14-11-16(21(29)27-17-5-2-1-3-6-17)13-19(18(14)12-15)28-22-25-9-4-10-26-22/h1-13H,(H3,23,24)(H,27,29)(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against plasmin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50147088 (6-Carbamimidoyl-4-furan-3-yl-naphthalene-2-carboxy...) Show SMILES NC(=N)c1ccc2cc(cc(-c3ccoc3)c2c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C22H17N3O2/c23-21(24)15-7-6-14-10-17(22(26)25-18-4-2-1-3-5-18)12-20(19(14)11-15)16-8-9-27-13-16/h1-13H,(H3,23,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against urokinase plasminogen activator				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138656 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1,2...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CNCCc2c1 Show InChI InChI=1S/C21H20N4O/c22-20(23)16-3-1-14-10-17(4-2-13(14)9-16)21(26)25-19-6-5-18-12-24-8-7-15(18)11-19/h1-6,9-11,24H,7-8,12H2,(H3,22,23)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50157084 (8-Furan-3-yl-6-styryl-naphthalene-2-carboxamidine ...) Show SMILES NC(=N)c1ccc2cc(\C=C\c3ccccc3)cc(-c3ccoc3)c2c1 Show InChI InChI=1S/C23H18N2O/c24-23(25)19-9-8-18-12-17(7-6-16-4-2-1-3-5-16)13-21(22(18)14-19)20-10-11-26-15-20/h1-15H,(H3,24,25)/b7-6+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against trypsin				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM50147096 (6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalen...) Show SMILES NC(=N)c1ccc2cc(cc(Nc3ncccn3)c2c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C22H18N6O/c23-20(24)15-8-7-14-11-16(21(29)27-17-5-2-1-3-6-17)13-19(18(14)12-15)28-22-25-9-4-10-26-22/h1-13H,(H3,23,24)(H,27,29)(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity value against kallikrein				Bioorg Med Chem Lett 15: 93-8 (2004) Article DOI: 10.1016/j.bmcl.2004.10.026 BindingDB Entry DOI: 10.7270/Q2R210W5
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138681 (6-Carbamimidoyl-naphthalene-2-carboxylic acid [3-(...) Show SMILES CCC(CC)Oc1cccc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)c1 Show InChI InChI=1S/C23H25N3O2/c1-3-20(4-2)28-21-7-5-6-19(14-21)26-23(27)18-11-9-15-12-17(22(24)25)10-8-16(15)13-18/h5-14,20H,3-4H2,1-2H3,(H3,24,25)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM50138656 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1,2...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CNCCc2c1 Show InChI InChI=1S/C21H20N4O/c22-20(23)16-3-1-14-10-17(4-2-13(14)9-16)21(26)25-19-6-5-18-12-24-8-7-15(18)11-19/h1-6,9-11,24H,7-8,12H2,(H3,22,23)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against human plasma kallikrein.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM50138669 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...) Show SMILES CC(C)CC1NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 Show InChI InChI=1S/C25H28N4O/c1-15(2)11-23-22-14-21(8-7-16(22)9-10-28-23)29-25(30)20-6-4-17-12-19(24(26)27)5-3-18(17)13-20/h3-8,12-15,23,28H,9-11H2,1-2H3,(H3,26,27)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138669 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-i...) Show SMILES CC(C)CC1NCCc2ccc(NC(=O)c3ccc4cc(ccc4c3)C(N)=N)cc12 Show InChI InChI=1S/C25H28N4O/c1-15(2)11-23-22-14-21(8-7-16(22)9-10-28-23)29-25(30)20-6-4-17-12-19(24(26)27)5-3-18(17)13-20/h3-8,12-15,23,28H,9-11H2,1-2H3,(H3,26,27)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair

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