Compile Data Set for Download or QSAR

Found 491 hits with Last Name = 'pass' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50093085 (CHEMBL3586582) Show SMILES CN(CCCCCCOc1ccc2c(C)c(C)c(=O)oc2c1)Cc1ccccc1 Show InChI InChI=1S/C25H31NO3/c1-19-20(2)25(27)29-24-17-22(13-14-23(19)24)28-16-10-5-4-9-15-26(3)18-21-11-7-6-8-12-21/h6-8,11-14,17H,4-5,9-10,15-16,18H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Mixed type inhibition of electric eel AChE by Lineweaver-Burk plot				J Med Chem 58: 5561-78 (2015) Article DOI: 10.1021/acs.jmedchem.5b00599 BindingDB Entry DOI: 10.7270/Q26T0PCZ
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50093227 (CHEMBL3586608) Show SMILES Cl.CN(Cc1ccccc1)Cc1ccc(COc2ccc3c(CO)cc(=O)oc3c2)cc1 Show InChI InChI=1S/C17H13NO/c1-11-15-4-2-3-13-7-10-16(18(13)15)17(11)12-5-8-14(19)9-6-12/h2-10,19H,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Mixed type inhibition of electric eel AChE by Lineweaver-Burk plot				J Med Chem 58: 5561-78 (2015) Article DOI: 10.1021/acs.jmedchem.5b00599 BindingDB Entry DOI: 10.7270/Q26T0PCZ
					More data for this Ligand-Target Pair
Kallikrein-5 [D153N] (Homo sapiens (Human))	BDBM50154254 (CHEMBL3775705) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C26H34N2O6/c1-26(2,3)34-25(32)28-20(15-18-11-7-5-8-12-18)22(29)17-23(30)27-21(24(31)33-4)16-19-13-9-6-10-14-19/h5-14,20-22,29H,15-17H2,1-4H3,(H,27,30)(H,28,32)/t20-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal Fluminense Curated by ChEMBL					Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...				Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW
					More data for this Ligand-Target Pair
Kallikrein-5 [D153N] (Homo sapiens (Human))	BDBM50154253 (CHEMBL3775377) Show SMILES COC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C |r| Show InChI InChI=1S/C22H34N2O6/c1-14(2)19(20(27)29-6)24-18(26)13-17(25)16(12-15-10-8-7-9-11-15)23-21(28)30-22(3,4)5/h7-11,14,16-17,19,25H,12-13H2,1-6H3,(H,23,28)(H,24,26)/t16-,17-,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal Fluminense Curated by ChEMBL					Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...				Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW
					More data for this Ligand-Target Pair
Kallikrein-5 [D153N] (Homo sapiens (Human))	BDBM50154252 (CHEMBL3774934) Show SMILES COC(=O)[C@@H]1CCCN1C(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C22H32N2O6/c1-22(2,3)30-21(28)23-16(13-15-9-6-5-7-10-15)18(25)14-19(26)24-12-8-11-17(24)20(27)29-4/h5-7,9-10,16-18,25H,8,11-14H2,1-4H3,(H,23,28)/t16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal Fluminense Curated by ChEMBL					Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...				Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078022 (CHEMBL3417402) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccc(cc1)N(C)C |c:14| Show InChI InChI=1S/C26H27N5O3/c1-5-34-24-9-7-6-8-23(24)27-28-25-17(2)29-31(26(25)33)21-14-19(15-22(32)16-21)18-10-12-20(13-11-18)30(3)4/h6-16,27,32H,5H2,1-4H3/b28-25-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078029 (CHEMBL3417409) Show SMILES CN(C)c1ccc(cc1)-c1cc(O)cc(c1)N1N=C(C)\C(=N\Nc2ccc3ccccc3c2)C1=O |t:19| Show InChI InChI=1S/C28H25N5O2/c1-18-27(30-29-23-11-8-19-6-4-5-7-21(19)14-23)28(35)33(31-18)25-15-22(16-26(34)17-25)20-9-12-24(13-10-20)32(2)3/h4-17,29,34H,1-3H3/b30-27-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078015 (CHEMBL3417395) Show SMILES CCOc1ccccc1N\N=C1/C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:14| Show InChI InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,23H,3H2,1-2H3/b24-19+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078027 (CHEMBL3417407) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccc(cc1)C(C)C |c:14| Show InChI InChI=1S/C27H28N4O3/c1-5-34-25-9-7-6-8-24(25)28-29-26-18(4)30-31(27(26)33)22-14-21(15-23(32)16-22)20-12-10-19(11-13-20)17(2)3/h6-17,28,32H,5H2,1-4H3/b29-26-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078026 (CHEMBL3417406) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1cccc(N)c1 |c:14| Show InChI InChI=1S/C24H23N5O3/c1-3-32-22-10-5-4-9-21(22)26-27-23-15(2)28-29(24(23)31)19-12-17(13-20(30)14-19)16-7-6-8-18(25)11-16/h4-14,26,30H,3,25H2,1-2H3/b27-23-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078028 (CHEMBL3417408) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cccc(c1)-c1ccc(cc1)N(C)C |c:14| Show InChI InChI=1S/C26H27N5O2/c1-5-33-24-12-7-6-11-23(24)27-28-25-18(2)29-31(26(25)32)22-10-8-9-20(17-22)19-13-15-21(16-14-19)30(3)4/h6-17,27H,5H2,1-4H3/b28-25-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078016 (CHEMBL3417396) Show SMILES CC1=NN(C(=O)\C1=C\C(c1ccccc1)c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C27H21N3OS/c1-19-23(17-24(20-11-5-2-6-12-20)21-13-7-3-8-14-21)26(31)30(29-19)27-28-25(18-32-27)22-15-9-4-10-16-22/h2-18,24H,1H3/b23-17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078017 (CHEMBL3417397) Show SMILES CC1=NN(C(=O)\C1=C\c1ccc(cc1)-c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C26H19N3OS/c1-18-23(16-19-12-14-21(15-13-19)20-8-4-2-5-9-20)25(30)29(28-18)26-27-24(17-31-26)22-10-6-3-7-11-22/h2-17H,1H3/b23-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078024 (CHEMBL3417404) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccncc1 |c:14| Show InChI InChI=1S/C23H21N5O3/c1-3-31-21-7-5-4-6-20(21)25-26-22-15(2)27-28(23(22)30)18-12-17(13-19(29)14-18)16-8-10-24-11-9-16/h4-14,25,29H,3H2,1-2H3/b26-22-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078027 (CHEMBL3417407) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccc(cc1)C(C)C |c:14| Show InChI InChI=1S/C27H28N4O3/c1-5-34-25-9-7-6-8-24(25)28-29-26-18(4)30-31(27(26)33)22-14-21(15-23(32)16-22)20-12-10-19(11-13-20)17(2)3/h6-17,28,32H,5H2,1-4H3/b29-26-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078030 (CHEMBL3417410) Show SMILES CC1=NN(C(=O)\C1=C\c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C20H15N3OS/c1-14-17(12-15-8-4-2-5-9-15)19(24)23(22-14)20-21-18(13-25-20)16-10-6-3-7-11-16/h2-13H,1H3/b17-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078019 (CHEMBL3417399) Show SMILES CC1=NN(C(=O)\C1=C\c1ncc[nH]1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C17H13N5OS/c1-11-13(9-15-18-7-8-19-15)16(23)22(21-11)17-20-14(10-24-17)12-5-3-2-4-6-12/h2-10H,1H3,(H,18,19)/b13-9+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078018 (CHEMBL3417398) Show SMILES CC1=NN(C(=O)\C1=C\c1ccc2ccccc2c1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C24H17N3OS/c1-16-21(14-17-11-12-18-7-5-6-10-20(18)13-17)23(28)27(26-16)24-25-22(15-29-24)19-8-3-2-4-9-19/h2-15H,1H3/b21-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078030 (CHEMBL3417410) Show SMILES CC1=NN(C(=O)\C1=C\c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C20H15N3OS/c1-14-17(12-15-8-4-2-5-9-15)19(24)23(22-14)20-21-18(13-25-20)16-10-6-3-7-11-16/h2-13H,1H3/b17-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078030 (CHEMBL3417410) Show SMILES CC1=NN(C(=O)\C1=C\c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C20H15N3OS/c1-14-17(12-15-8-4-2-5-9-15)19(24)23(22-14)20-21-18(13-25-20)16-10-6-3-7-11-16/h2-13H,1H3/b17-12+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078015 (CHEMBL3417395) Show SMILES CCOc1ccccc1N\N=C1/C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:14| Show InChI InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,23H,3H2,1-2H3/b24-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078017 (CHEMBL3417397) Show SMILES CC1=NN(C(=O)\C1=C\c1ccc(cc1)-c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C26H19N3OS/c1-18-23(16-19-12-14-21(15-13-19)20-8-4-2-5-9-20)25(30)29(28-18)26-27-24(17-31-26)22-10-6-3-7-11-22/h2-17H,1H3/b23-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078018 (CHEMBL3417398) Show SMILES CC1=NN(C(=O)\C1=C\c1ccc2ccccc2c1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C24H17N3OS/c1-16-21(14-17-11-12-18-7-5-6-10-20(18)13-17)23(28)27(26-16)24-25-22(15-29-24)19-8-3-2-4-9-19/h2-15H,1H3/b21-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078029 (CHEMBL3417409) Show SMILES CN(C)c1ccc(cc1)-c1cc(O)cc(c1)N1N=C(C)\C(=N\Nc2ccc3ccccc3c2)C1=O |t:19| Show InChI InChI=1S/C28H25N5O2/c1-18-27(30-29-23-11-8-19-6-4-5-7-21(19)14-23)28(35)33(31-18)25-15-22(16-26(34)17-25)20-9-12-24(13-10-20)32(2)3/h4-17,29,34H,1-3H3/b30-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078028 (CHEMBL3417408) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cccc(c1)-c1ccc(cc1)N(C)C |c:14| Show InChI InChI=1S/C26H27N5O2/c1-5-33-24-12-7-6-11-23(24)27-28-25-18(2)29-31(26(25)32)22-10-8-9-20(17-22)19-13-15-21(16-14-19)30(3)4/h6-17,27H,5H2,1-4H3/b28-25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078019 (CHEMBL3417399) Show SMILES CC1=NN(C(=O)\C1=C\c1ncc[nH]1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C17H13N5OS/c1-11-13(9-15-18-7-8-19-15)16(23)22(21-11)17-20-14(10-24-17)12-5-3-2-4-6-12/h2-10H,1H3,(H,18,19)/b13-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078023 (CHEMBL3417403) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccccc1 |c:14| Show InChI InChI=1S/C24H22N4O3/c1-3-31-22-12-8-7-11-21(22)25-26-23-16(2)27-28(24(23)30)19-13-18(14-20(29)15-19)17-9-5-4-6-10-17/h4-15,25,29H,3H2,1-2H3/b26-23-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078022 (CHEMBL3417402) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccc(cc1)N(C)C |c:14| Show InChI InChI=1S/C26H27N5O3/c1-5-34-24-9-7-6-8-23(24)27-28-25-17(2)29-31(26(25)33)21-14-19(15-22(32)16-21)18-10-12-20(13-11-18)30(3)4/h6-16,27,32H,5H2,1-4H3/b28-25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078018 (CHEMBL3417398) Show SMILES CC1=NN(C(=O)\C1=C\c1ccc2ccccc2c1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C24H17N3OS/c1-16-21(14-17-11-12-18-7-5-6-10-20(18)13-17)23(28)27(26-16)24-25-22(15-29-24)19-8-3-2-4-9-19/h2-15H,1H3/b21-14+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078017 (CHEMBL3417397) Show SMILES CC1=NN(C(=O)\C1=C\c1ccc(cc1)-c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C26H19N3OS/c1-18-23(16-19-12-14-21(15-13-19)20-8-4-2-5-9-20)25(30)29(28-18)26-27-24(17-31-26)22-10-6-3-7-11-22/h2-17H,1H3/b23-16+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078016 (CHEMBL3417396) Show SMILES CC1=NN(C(=O)\C1=C\C(c1ccccc1)c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C27H21N3OS/c1-19-23(17-24(20-11-5-2-6-12-20)21-13-7-3-8-14-21)26(31)30(29-19)27-28-25(18-32-27)22-15-9-4-10-16-22/h2-18,24H,1H3/b23-17+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078027 (CHEMBL3417407) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccc(cc1)C(C)C |c:14| Show InChI InChI=1S/C27H28N4O3/c1-5-34-25-9-7-6-8-24(25)28-29-26-18(4)30-31(27(26)33)22-14-21(15-23(32)16-22)20-12-10-19(11-13-20)17(2)3/h6-17,28,32H,5H2,1-4H3/b29-26-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078019 (CHEMBL3417399) Show SMILES CC1=NN(C(=O)\C1=C\c1ncc[nH]1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C17H13N5OS/c1-11-13(9-15-18-7-8-19-15)16(23)22(21-11)17-20-14(10-24-17)12-5-3-2-4-6-12/h2-10H,1H3,(H,18,19)/b13-9+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078025 (CHEMBL3417405) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1cccs1 |c:14| Show InChI InChI=1S/C22H20N4O3S/c1-3-29-19-8-5-4-7-18(19)23-24-21-14(2)25-26(22(21)28)16-11-15(12-17(27)13-16)20-9-6-10-30-20/h4-13,23,27H,3H2,1-2H3/b24-21-	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078024 (CHEMBL3417404) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccncc1 |c:14| Show InChI InChI=1S/C23H21N5O3/c1-3-31-21-7-5-4-6-20(21)25-26-22-15(2)27-28(23(22)30)18-12-17(13-19(29)14-18)16-8-10-24-11-9-16/h4-14,25,29H,3H2,1-2H3/b26-22-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078029 (CHEMBL3417409) Show SMILES CN(C)c1ccc(cc1)-c1cc(O)cc(c1)N1N=C(C)\C(=N\Nc2ccc3ccccc3c2)C1=O |t:19| Show InChI InChI=1S/C28H25N5O2/c1-18-27(30-29-23-11-8-19-6-4-5-7-21(19)14-23)28(35)33(31-18)25-15-22(16-26(34)17-25)20-9-12-24(13-10-20)32(2)3/h4-17,29,34H,1-3H3/b30-27-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078020 (CHEMBL3417400) Show SMILES CCOc1ccccc1CC(=O)C1C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:15| Show InChI InChI=1S/C23H21N3O3S/c1-3-29-20-12-8-7-11-17(20)13-19(27)21-15(2)25-26(22(21)28)23-24-18(14-30-23)16-9-5-4-6-10-16/h4-12,14,21H,3,13H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50078021 (CHEMBL3417401) Show SMILES CCOc1ccccc1C(=O)C(=O)C1C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:16| Show InChI InChI=1S/C23H19N3O4S/c1-3-30-18-12-8-7-11-16(18)20(27)21(28)19-14(2)25-26(22(19)29)23-24-17(13-31-23)15-9-5-4-6-10-15/h4-13,19H,3H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078028 (CHEMBL3417408) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cccc(c1)-c1ccc(cc1)N(C)C |c:14| Show InChI InChI=1S/C26H27N5O2/c1-5-33-24-12-7-6-11-23(24)27-28-25-18(2)29-31(26(25)32)22-10-8-9-20(17-22)19-13-15-21(16-14-19)30(3)4/h6-17,27H,5H2,1-4H3/b28-25-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078021 (CHEMBL3417401) Show SMILES CCOc1ccccc1C(=O)C(=O)C1C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:16| Show InChI InChI=1S/C23H19N3O4S/c1-3-30-18-12-8-7-11-16(18)20(27)21(28)19-14(2)25-26(22(19)29)23-24-17(13-31-23)15-9-5-4-6-10-15/h4-13,19H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078026 (CHEMBL3417406) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1cccc(N)c1 |c:14| Show InChI InChI=1S/C24H23N5O3/c1-3-32-22-10-5-4-9-21(22)26-27-23-15(2)28-29(24(23)31)19-12-17(13-20(30)14-19)16-7-6-8-18(25)11-16/h4-14,26,30H,3,25H2,1-2H3/b27-23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078025 (CHEMBL3417405) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1cccs1 |c:14| Show InChI InChI=1S/C22H20N4O3S/c1-3-29-19-8-5-4-7-18(19)23-24-21-14(2)25-26(22(21)28)16-11-15(12-17(27)13-16)20-9-6-10-30-20/h4-13,23,27H,3H2,1-2H3/b24-21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078024 (CHEMBL3417404) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccncc1 |c:14| Show InChI InChI=1S/C23H21N5O3/c1-3-31-21-7-5-4-6-20(21)25-26-22-15(2)27-28(23(22)30)18-12-17(13-19(29)14-18)16-8-10-24-11-9-16/h4-14,25,29H,3H2,1-2H3/b26-22-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078023 (CHEMBL3417403) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccccc1 |c:14| Show InChI InChI=1S/C24H22N4O3/c1-3-31-22-12-8-7-11-21(22)25-26-23-16(2)27-28(24(23)30)19-13-18(14-20(29)15-19)17-9-5-4-6-10-17/h4-15,25,29H,3H2,1-2H3/b26-23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50078020 (CHEMBL3417400) Show SMILES CCOc1ccccc1CC(=O)C1C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:15| Show InChI InChI=1S/C23H21N3O3S/c1-3-29-20-12-8-7-11-17(20)13-19(27)21-15(2)25-26(22(21)28)23-24-18(14-30-23)16-9-5-4-6-10-16/h4-12,14,21H,3,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078015 (CHEMBL3417395) Show SMILES CCOc1ccccc1N\N=C1/C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:14| Show InChI InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,23H,3H2,1-2H3/b24-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078016 (CHEMBL3417396) Show SMILES CC1=NN(C(=O)\C1=C\C(c1ccccc1)c1ccccc1)c1nc(cs1)-c1ccccc1 |t:1| Show InChI InChI=1S/C27H21N3OS/c1-19-23(17-24(20-11-5-2-6-12-20)21-13-7-3-8-14-21)26(31)30(29-19)27-28-25(18-32-27)22-15-9-4-10-16-22/h2-18,24H,1H3/b23-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078026 (CHEMBL3417406) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1cccc(N)c1 |c:14| Show InChI InChI=1S/C24H23N5O3/c1-3-32-22-10-5-4-9-21(22)26-27-23-15(2)28-29(24(23)31)19-12-17(13-20(30)14-19)16-7-6-8-18(25)11-16/h4-14,26,30H,3,25H2,1-2H3/b27-23-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078025 (CHEMBL3417405) Show SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1cccs1 |c:14| Show InChI InChI=1S/C22H20N4O3S/c1-3-29-19-8-5-4-7-18(19)23-24-21-14(2)25-26(22(21)28)16-11-15(12-17(27)13-16)20-9-6-10-30-20/h4-13,23,27H,3H2,1-2H3/b24-21-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50078020 (CHEMBL3417400) Show SMILES CCOc1ccccc1CC(=O)C1C(C)=NN(C1=O)c1nc(cs1)-c1ccccc1 |c:15| Show InChI InChI=1S/C23H21N3O3S/c1-3-29-20-12-8-7-11-17(20)13-19(27)21-15(2)25-26(22(21)28)23-24-18(14-30-23)16-9-5-4-6-10-16/h4-12,14,21H,3,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay				J Med Chem 58: 2135-48 (2015) Article DOI: 10.1021/jm501123r BindingDB Entry DOI: 10.7270/Q2X35055
					More data for this Ligand-Target Pair

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