Found 544 hits with Last Name = 'phelan' and Initial = 'k' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220468
(CHEMBL61120)Show InChI InChI=1S/C20H29N3O3/c21-9-8-19(24)23-13-11-22(12-14-23)10-1-15-26-18-6-4-17(5-7-18)20(25)16-2-3-16/h4-7,16H,1-3,8-15,21H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220419
(CHEMBL63125)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)[C@@H](C)NC(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C27H43N3O5/c1-6-7-8-10-24(31)22-11-13-23(14-12-22)34-20-9-15-29-16-18-30(19-17-29)25(32)21(2)28-26(33)35-27(3,4)5/h11-14,21H,6-10,15-20H2,1-5H3,(H,28,33)/t21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50139308
((R)-2-Amino-1-{4-[3-(4-cyclopropanecarbonyl-phenox...)Show SMILES C[C@@H](N)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C20H29N3O3/c1-15(21)20(25)23-12-10-22(11-13-23)9-2-14-26-18-7-5-17(6-8-18)19(24)16-3-4-16/h5-8,15-16H,2-4,9-14,21H2,1H3/t15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220473
(CHEMBL305144)Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H]2CCN2)cc1 Show InChI InChI=1S/C21H29N3O3/c25-20(16-2-3-16)17-4-6-18(7-5-17)27-15-1-10-23-11-13-24(14-12-23)21(26)19-8-9-22-19/h4-7,16,19,22H,1-3,8-15H2/t19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119707
(4-[3-(4-Hexanoyl-phenoxy)-propyl]-piperazine-1-car...)Show InChI InChI=1S/C22H34N2O4/c1-3-5-6-8-21(25)19-9-11-20(12-10-19)28-18-7-13-23-14-16-24(17-15-23)22(26)27-4-2/h9-12H,3-8,13-18H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220467
(CHEMBL62421)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)[C@@H](C)N)cc1 Show InChI InChI=1S/C22H35N3O3/c1-3-4-5-7-21(26)19-8-10-20(11-9-19)28-17-6-12-24-13-15-25(16-14-24)22(27)18(2)23/h8-11,18H,3-7,12-17,23H2,1-2H3/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220430
(CHEMBL302829)Show SMILES CC[C@@H](N)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C21H31N3O3/c1-2-19(22)21(26)24-13-11-23(12-14-24)10-3-15-27-18-8-6-17(7-9-18)20(25)16-4-5-16/h6-9,16,19H,2-5,10-15,22H2,1H3/t19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220430
(CHEMBL302829)Show SMILES CC[C@@H](N)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C21H31N3O3/c1-2-19(22)21(26)24-13-11-23(12-14-24)10-3-15-27-18-8-6-17(7-9-18)20(25)16-4-5-16/h6-9,16,19H,2-5,10-15,22H2,1H3/t19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220338
(CHEMBL302886)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)C2CC2)cc1 Show InChI InChI=1S/C23H34N2O3/c1-2-3-4-6-22(26)19-9-11-21(12-10-19)28-18-5-13-24-14-16-25(17-15-24)23(27)20-7-8-20/h9-12,20H,2-8,13-18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220417
(CHEMBL64406)Show SMILES C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C25H37N3O5/c1-18(26-24(31)33-25(2,3)4)23(30)28-15-13-27(14-16-28)12-5-17-32-21-10-8-20(9-11-21)22(29)19-6-7-19/h8-11,18-19H,5-7,12-17H2,1-4H3,(H,26,31)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220422
(CHEMBL60401)Show InChI InChI=1S/C20H29N3O3/c1-21-15-19(24)23-12-10-22(11-13-23)9-2-14-26-18-7-5-17(6-8-18)20(25)16-3-4-16/h5-8,16,21H,2-4,9-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220449
(CHEMBL60837)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)[C@@H](CO)NC(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C27H43N3O6/c1-5-6-7-9-24(32)21-10-12-22(13-11-21)35-19-8-14-29-15-17-30(18-16-29)25(33)23(20-31)28-26(34)36-27(2,3)4/h10-13,23,31H,5-9,14-20H2,1-4H3,(H,28,34)/t23-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220428
(CHEMBL418666)Show SMILES CC[C@H](N)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C21H31N3O3/c1-2-19(22)21(26)24-13-11-23(12-14-24)10-3-15-27-18-8-6-17(7-9-18)20(25)16-4-5-16/h6-9,16,19H,2-5,10-15,22H2,1H3/t19-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220339
(CHEMBL64408)Show InChI InChI=1S/C21H32N2O4/c1-3-4-5-7-20(24)18-8-10-19(11-9-18)27-17-6-12-22-13-15-23(16-14-22)21(25)26-2/h8-11H,3-7,12-17H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220401
(CHEMBL294502)Show InChI InChI=1S/C22H34N2O3/c1-3-5-6-8-21(25)19-9-11-20(12-10-19)27-18-7-13-23-14-16-24(17-15-23)22(26)4-2/h9-12H,3-8,13-18H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220101
(CHEMBL64100)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)C2CCC2)cc1 Show InChI InChI=1S/C24H36N2O3/c1-2-3-4-9-23(27)20-10-12-22(13-11-20)29-19-6-14-25-15-17-26(18-16-25)24(28)21-7-5-8-21/h10-13,21H,2-9,14-19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220109
(CHEMBL304714)Show InChI InChI=1S/C20H30N2O4/c1-3-6-19(23)17-7-9-18(10-8-17)26-16-5-11-21-12-14-22(15-13-21)20(24)25-4-2/h7-10H,3-6,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220143
(CHEMBL449040)Show SMILES CCCCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)OCC)cc1 Show InChI InChI=1S/C24H38N2O4/c1-3-5-6-7-8-10-23(27)21-11-13-22(14-12-21)30-20-9-15-25-16-18-26(19-17-25)24(28)29-4-2/h11-14H,3-10,15-20H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220457
(CHEMBL60143)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C31H41N3O5/c1-31(2,3)39-30(37)32-27(22-23-8-5-4-6-9-23)29(36)34-19-17-33(18-20-34)16-7-21-38-26-14-12-25(13-15-26)28(35)24-10-11-24/h4-6,8-9,12-15,24,27H,7,10-11,16-22H2,1-3H3,(H,32,37)/t27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220434
(CHEMBL291821)Show SMILES CCC[C@@H](N)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C22H33N3O3/c1-2-4-20(23)22(27)25-14-12-24(13-15-25)11-3-16-28-19-9-7-18(8-10-19)21(26)17-5-6-17/h7-10,17,20H,2-6,11-16,23H2,1H3/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220400
(CHEMBL64884)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2cccn2C)cc1 Show InChI InChI=1S/C25H35N3O3/c1-3-4-5-9-24(29)21-10-12-22(13-11-21)31-20-7-15-27-16-18-28(19-17-27)25(30)23-8-6-14-26(23)2/h6,8,10-14H,3-5,7,9,15-20H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220459
(CHEMBL62596)Show SMILES O=C(C1CC1)c1ccc(OCCCN2CCN(CC2)[C@@H]2CC(=O)N2)cc1 Show InChI InChI=1S/C20H27N3O3/c24-19-14-18(21-19)23-11-9-22(10-12-23)8-1-13-26-17-6-4-16(5-7-17)20(25)15-2-3-15/h4-7,15,18H,1-3,8-14H2,(H,21,24)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220396
(CHEMBL62527)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)C(C)C)cc1 Show InChI InChI=1S/C23H36N2O3/c1-4-5-6-8-22(26)20-9-11-21(12-10-20)28-18-7-13-24-14-16-25(17-15-24)23(27)19(2)3/h9-12,19H,4-8,13-18H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220008
(CHEMBL59715)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2c[nH]cn2)cc1 Show InChI InChI=1S/C23H32N4O3/c1-2-3-4-6-22(28)19-7-9-20(10-8-19)30-16-5-11-26-12-14-27(15-13-26)23(29)21-17-24-18-25-21/h7-10,17-18H,2-6,11-16H2,1H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220439
(CHEMBL64059)Show SMILES N[C@H](CCc1ccccc1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C27H35N3O3/c28-25(14-7-21-5-2-1-3-6-21)27(32)30-18-16-29(17-19-30)15-4-20-33-24-12-10-23(11-13-24)26(31)22-8-9-22/h1-3,5-6,10-13,22,25H,4,7-9,14-20,28H2/t25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220437
(CHEMBL61792)Show SMILES N[C@H](Cc1c[nH]cn1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C23H31N5O3/c24-21(14-19-15-25-16-26-19)23(30)28-11-9-27(10-12-28)8-1-13-31-20-6-4-18(5-7-20)22(29)17-2-3-17/h4-7,15-17,21H,1-3,8-14,24H2,(H,25,26)/t21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220433
(CHEMBL60435)Show SMILES O=C(C[C@H]1CCCN1)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C23H33N3O3/c27-22(17-20-3-1-10-24-20)26-14-12-25(13-15-26)11-2-16-29-21-8-6-19(7-9-21)23(28)18-4-5-18/h6-9,18,20,24H,1-5,10-17H2/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220403
(CHEMBL62948)Show InChI InChI=1S/C20H28N2O4/c1-2-25-20(24)22-13-11-21(12-14-22)10-3-15-26-18-8-6-17(7-9-18)19(23)16-4-5-16/h6-9,16H,2-5,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220113
(CHEMBL62840)Show InChI InChI=1S/C18H26N2O4/c1-3-23-18(22)20-12-10-19(11-13-20)9-4-14-24-17-7-5-16(6-8-17)15(2)21/h5-8H,3-4,9-14H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220333
(CHEMBL64259)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)OC(C)C)cc1 Show InChI InChI=1S/C23H36N2O4/c1-4-5-6-8-22(26)20-9-11-21(12-10-20)28-18-7-13-24-14-16-25(17-15-24)23(27)29-19(2)3/h9-12,19H,4-8,13-18H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220142
(CHEMBL62066)Show InChI InChI=1S/C19H28N2O4/c1-3-18(22)16-6-8-17(9-7-16)25-15-5-10-20-11-13-21(14-12-20)19(23)24-4-2/h6-9H,3-5,10-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220461
(CHEMBL59733)Show SMILES N[C@H](Cc1nccs1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C23H30N4O3S/c24-20(16-21-25-8-15-31-21)23(29)27-12-10-26(11-13-27)9-1-14-30-19-6-4-18(5-7-19)22(28)17-2-3-17/h4-8,15,17,20H,1-3,9-14,16,24H2/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220341
(CHEMBL65518)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)N2CCOCC2)cc1 Show InChI InChI=1S/C24H37N3O4/c1-2-3-4-6-23(28)21-7-9-22(10-8-21)31-18-5-11-25-12-14-26(15-13-25)24(29)27-16-19-30-20-17-27/h7-10H,2-6,11-20H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220104
(CHEMBL444307)Show SMILES CCOC(=O)N1CCN(CCCOc2ccc(cc2)C(=O)\C=C\c2cccnc2)CC1 Show InChI InChI=1S/C24H29N3O4/c1-2-30-24(29)27-16-14-26(15-17-27)13-4-18-31-22-9-7-21(8-10-22)23(28)11-6-20-5-3-12-25-19-20/h3,5-12,19H,2,4,13-18H2,1H3/b11-6+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220404
(CHEMBL291394)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2ccncc2)cc1 Show InChI InChI=1S/C25H33N3O3/c1-2-3-4-6-24(29)21-7-9-23(10-8-21)31-20-5-15-27-16-18-28(19-17-27)25(30)22-11-13-26-14-12-22/h7-14H,2-6,15-20H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220427
(CHEMBL64608)Show SMILES C[C@@H](CN)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C21H31N3O3/c1-16(15-22)21(26)24-12-10-23(11-13-24)9-2-14-27-19-7-5-18(6-8-19)20(25)17-3-4-17/h5-8,16-17H,2-4,9-15,22H2,1H3/t16-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220340
(CHEMBL64479)Show InChI InChI=1S/C23H36N2O3/c1-3-5-6-9-22(26)20-10-12-21(13-11-20)28-19-7-14-24-15-17-25(18-16-24)23(27)8-4-2/h10-13H,3-9,14-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220471
(CHEMBL62660)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H](N)CO)cc1 Show InChI InChI=1S/C22H35N3O4/c1-2-3-4-6-21(27)18-7-9-19(10-8-18)29-16-5-11-24-12-14-25(15-13-24)22(28)20(23)17-26/h7-10,20,26H,2-6,11-17,23H2,1H3/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220107
(CHEMBL61231)Show SMILES CCOC(=O)N1CCN(CCCOc2ccc(cc2)C(=O)CC(C)C)CC1 Show InChI InChI=1S/C21H32N2O4/c1-4-26-21(25)23-13-11-22(12-14-23)10-5-15-27-19-8-6-18(7-9-19)20(24)16-17(2)3/h6-9,17H,4-5,10-16H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220213
(CHEMBL292275)Show SMILES CCOC(=O)N1CCN(CCCOc2ccc(cc2)C(=O)\C=C\c2ccc(OC)cc2)CC1 Show InChI InChI=1S/C26H32N2O5/c1-3-32-26(30)28-18-16-27(17-19-28)15-4-20-33-24-12-8-22(9-13-24)25(29)14-7-21-5-10-23(31-2)11-6-21/h5-14H,3-4,15-20H2,1-2H3/b14-7+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220099
(CHEMBL64667)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)N2CCCC2)cc1 Show InChI InChI=1S/C24H37N3O3/c1-2-3-4-8-23(28)21-9-11-22(12-10-21)30-20-7-13-25-16-18-27(19-17-25)24(29)26-14-5-6-15-26/h9-12H,2-8,13-20H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220402
(CHEMBL62949)Show SMILES CCCCCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)OCC)cc1 Show InChI InChI=1S/C25H40N2O4/c1-3-5-6-7-8-9-11-24(28)22-12-14-23(15-13-22)31-21-10-16-26-17-19-27(20-18-26)25(29)30-4-2/h12-15H,3-11,16-21H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220408
(CHEMBL61396)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2occc2C)cc1 Show InChI InChI=1S/C25H34N2O4/c1-3-4-5-7-23(28)21-8-10-22(11-9-21)30-18-6-13-26-14-16-27(17-15-26)25(29)24-20(2)12-19-31-24/h8-12,19H,3-7,13-18H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220470
(CHEMBL293033)Show SMILES CC(C)(C)OC[C@@H](N)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C24H37N3O4/c1-24(2,3)31-17-21(25)23(29)27-14-12-26(13-15-27)11-4-16-30-20-9-7-19(8-10-20)22(28)18-5-6-18/h7-10,18,21H,4-6,11-17,25H2,1-3H3/t21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220460
(CHEMBL304888)Show SMILES CC(C)N[C@H](C)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C23H35N3O3/c1-17(2)24-18(3)23(28)26-14-12-25(13-15-26)11-4-16-29-21-9-7-20(8-10-21)22(27)19-5-6-19/h7-10,17-19,24H,4-6,11-16H2,1-3H3/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220426
(CHEMBL61288)Show SMILES C[C@H](CN)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1 Show InChI InChI=1S/C21H31N3O3/c1-16(15-22)21(26)24-12-10-23(11-13-24)9-2-14-27-19-7-5-18(6-8-19)20(25)17-3-4-17/h5-8,16-17H,2-4,9-15,22H2,1H3/t16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220472
(CHEMBL64321)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)[C@H](N)Cc2ccncc2)cc1 Show InChI InChI=1S/C27H38N4O3/c1-2-3-4-6-26(32)23-7-9-24(10-8-23)34-20-5-15-30-16-18-31(19-17-30)27(33)25(28)21-22-11-13-29-14-12-22/h7-14,25H,2-6,15-21,28H2,1H3/t25-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 9.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards Histamine H3 receptor of rat cortical membranes. |
Bioorg Med Chem Lett 12: 2035-7 (2002)
BindingDB Entry DOI: 10.7270/Q2RB75SX |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220105
(CHEMBL59798)Show InChI InChI=1S/C23H38N2O2/c1-4-5-6-8-23(26)21-9-11-22(12-10-21)27-18-7-13-24-14-16-25(17-15-24)19-20(2)3/h9-12,20H,4-8,13-19H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220116
(CHEMBL64773)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)NC(C)C)cc1 Show InChI InChI=1S/C23H37N3O3/c1-4-5-6-8-22(27)20-9-11-21(12-10-20)29-18-7-13-25-14-16-26(17-15-25)23(28)24-19(2)3/h9-12,19H,4-8,13-18H2,1-3H3,(H,24,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220407
(CHEMBL305338)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C27H36N2O3/c1-2-3-5-11-26(30)24-12-14-25(15-13-24)32-21-8-16-28-17-19-29(20-18-28)27(31)22-23-9-6-4-7-10-23/h4,6-7,9-10,12-15H,2-3,5,8,11,16-22H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this
Ligand-Target Pair | |
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