Compile Data Set for Download or QSAR

Found 197 hits with Last Name = 'ravache' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM25045 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassay				Eur J Med Chem 57: 225-33 (2012) Article DOI: 10.1016/j.ejmech.2012.09.001 BindingDB Entry DOI: 10.7270/Q2RF5W4C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161356 (CHEMBL3786536) Show SMILES Cc1cnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)cn1 Show InChI InChI=1S/C16H12BrN3O/c1-8-2-3-9-7-11-14(10(9)6-8)19-16(18)20-15(11)12-4-5-13(17)21-12/h2-6H,7H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399310 (CHEMBL2180854) Show SMILES Brc1ccnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c1 Show InChI InChI=1S/C18H17BrN4O2/c19-11-7-8-20-15(10-11)22-18(25)21-13-5-3-4-12-16(13)14-6-1-2-9-23(14)17(12)24/h3-5,7-8,10,14H,1-2,6,9H2,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161347 (CHEMBL3786624) Show SMILES O=Cc1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C16H13N3O/c1-9-4-5-10-8-12-14(11(10)7-9)18-16(17)19-15(12)13-3-2-6-20-13/h2-7H,8H2,1H3,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161348 (CHEMBL3785408) Show SMILES Cc1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C17H14N4/c1-10-2-3-12-9-14-15(11-4-6-19-7-5-11)20-17(18)21-16(14)13(12)8-10/h2-8H,9H2,1H3,(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399303 (CHEMBL2180844) Show SMILES Oc1cccnc1NC(=O)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C18H18N4O3/c23-14-8-4-9-19-16(14)21-18(25)20-12-6-3-5-11-15(12)13-7-1-2-10-22(13)17(11)24/h3-6,8-9,13,23H,1-2,7,10H2,(H2,19,20,21,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399312 (CHEMBL2180852) Show SMILES Brc1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C18H17BrN4O2/c19-14-8-4-9-15(21-14)22-18(25)20-12-6-3-5-11-16(12)13-7-1-2-10-23(13)17(11)24/h3-6,8-9,13H,1-2,7,10H2,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161338 (CHEMBL3787480) Show SMILES Cc1ccnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c1 Show InChI InChI=1S/C17H15N3O2/c1-9-2-3-10-7-13-15(12(10)6-9)19-17(18)20-16(13)14-5-4-11(8-21)22-14/h2-6,21H,7-8H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161339 (CHEMBL3787512) Show SMILES OCc1ccnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c1 Show InChI InChI=1S/C15H9BrClN3O/c16-12-4-3-11(21-12)14-10-5-7-1-2-8(17)6-9(7)13(10)19-15(18)20-14/h1-4,6H,5H2,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161398 (CHEMBL3787292) Show SMILES FCc1ccnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c1 Show InChI InChI=1S/C19H19FN4O2/c20-11-12-7-8-21-16(10-12)23-19(26)22-14-5-3-4-13-17(14)15-6-1-2-9-24(15)18(13)25/h3-5,7-8,10,15H,1-2,6,9,11H2,(H2,21,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161345 (CHEMBL3785575) Show SMILES Cc1ccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)nc1 Show InChI InChI=1S/C16H12BrN3O2/c1-21-9-3-2-8-6-11-14(10(8)7-9)19-16(18)20-15(11)12-4-5-13(17)22-12/h2-5,7H,6H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				Bioorg Med Chem Lett 24: 5037-40 (2014) Article DOI: 10.1016/j.bmcl.2014.09.017 BindingDB Entry DOI: 10.7270/Q27H1M51
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161344 (CHEMBL3786276) Show SMILES O=C(Nc1cc(CN2CCOCC2)ccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C18H15N3/c19-18-20-16(13-7-2-1-3-8-13)15-11-10-12-6-4-5-9-14(12)17(15)21-18/h1-9H,10-11H2,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399315 (CHEMBL2180849) Show SMILES O=C(Nc1cc2ccccc2cn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C22H20N4O2/c27-21-16-8-5-9-17(20(16)18-10-3-4-11-26(18)21)24-22(28)25-19-12-14-6-1-2-7-15(14)13-23-19/h1-2,5-9,12-13,18H,3-4,10-11H2,(H2,23,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399326 (CHEMBL2180863) Show SMILES O=C(Nc1cnccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C17H17N5O2/c23-16-11-4-3-5-12(15(11)13-6-1-2-9-22(13)16)20-17(24)21-14-10-18-7-8-19-14/h3-5,7-8,10,13H,1-2,6,9H2,(H2,19,20,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399301 (CHEMBL2180862) Show SMILES O=C(Nc1ccccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C18H18N4O2/c23-17-12-6-5-7-13(16(12)14-8-2-4-11-22(14)17)20-18(24)21-15-9-1-3-10-19-15/h1,3,5-7,9-10,14H,2,4,8,11H2,(H2,19,20,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50399301 (CHEMBL2180862) Show SMILES O=C(Nc1ccccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C18H18N4O2/c23-17-12-6-5-7-13(16(12)14-8-2-4-11-22(14)17)20-18(24)21-15-9-1-3-10-19-15/h1,3,5-7,9-10,14H,2,4,8,11H2,(H2,19,20,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of CDK1				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399326 (CHEMBL2180863) Show SMILES O=C(Nc1cnccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C17H17N5O2/c23-16-11-4-3-5-12(15(11)13-6-1-2-9-22(13)16)20-17(24)21-14-10-18-7-8-19-14/h3-5,7-8,10,13H,1-2,6,9H2,(H2,19,20,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399301 (CHEMBL2180862) Show SMILES O=C(Nc1ccccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C18H18N4O2/c23-17-12-6-5-7-13(16(12)14-8-2-4-11-22(14)17)20-18(24)21-15-9-1-3-10-19-15/h1,3,5-7,9-10,14H,2,4,8,11H2,(H2,19,20,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399309 (CHEMBL2180855) Show SMILES Fc1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C18H17FN4O2/c19-14-8-4-9-15(21-14)22-18(25)20-12-6-3-5-11-16(12)13-7-1-2-10-23(13)17(11)24/h3-6,8-9,13H,1-2,7,10H2,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50391185 (CHEMBL2088663) Show SMILES Cc1n[nH]c(=O)c2n(Cc3cccc(c3)C#N)c3ccc(Br)cc3c12 Show InChI InChI=1S/C19H13BrN4O/c1-11-17-15-8-14(20)5-6-16(15)24(18(17)19(25)23-22-11)10-13-4-2-3-12(7-13)9-21/h2-8H,10H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassay				Eur J Med Chem 57: 225-33 (2012) Article DOI: 10.1016/j.ejmech.2012.09.001 BindingDB Entry DOI: 10.7270/Q2RF5W4C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161335 (CHEMBL3785571) Show SMILES Cc1cccnc1NC(=O)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C19H20N4O2/c1-12-6-5-10-20-17(12)22-19(25)21-14-8-4-7-13-16(14)15-9-2-3-11-23(15)18(13)24/h4-8,10,15H,2-3,9,11H2,1H3,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161346 (CHEMBL3786430) Show SMILES O=C(Nc1cc(CN2CCCCC2)ccn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C21H14BrN3O/c22-18-9-8-17(26-18)20-16-11-14-7-6-13(12-4-2-1-3-5-12)10-15(14)19(16)24-21(23)25-20/h1-10H,11H2,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161343 (CHEMBL3787557) Show SMILES CN1CCN(Cc2ccnc(NC(=O)Nc3cccc4C(=O)N5CCCCC5c34)c2)CC1 Show InChI InChI=1S/C16H16BrN3O/c1-8-2-3-9-7-11-14(10(9)6-8)19-16(18)20-15(11)12-4-5-13(17)21-12/h2-3,6,12-13H,4-5,7H2,1H3,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399311 (CHEMBL2180853) Show SMILES Brc1ccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)nc1 Show InChI InChI=1S/C18H17BrN4O2/c19-11-7-8-15(20-10-11)22-18(25)21-13-5-3-4-12-16(13)14-6-1-2-9-23(14)17(12)24/h3-5,7-8,10,14H,1-2,6,9H2,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM25045 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 Show InChI InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of PI3K p110gamma by fluorescence based immunoassay				Eur J Med Chem 57: 225-33 (2012) Article DOI: 10.1016/j.ejmech.2012.09.001 BindingDB Entry DOI: 10.7270/Q2RF5W4C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161396 (CHEMBL3785795) Show SMILES COc1cc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)nc2ccccc12 Show InChI InChI=1S/C23H22N4O3/c1-30-19-13-20(24-16-9-3-2-7-14(16)19)26-23(29)25-17-10-6-8-15-21(17)18-11-4-5-12-27(18)22(15)28/h2-3,6-10,13,18H,4-5,11-12H2,1H3,(H2,24,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161360 (CHEMBL3785771) Show SMILES Cc1nccnc1NC(=O)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C18H19N5O2/c1-11-16(20-9-8-19-11)22-18(25)21-13-6-4-5-12-15(13)14-7-2-3-10-23(14)17(12)24/h4-6,8-9,14H,2-3,7,10H2,1H3,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161349 (CHEMBL3786332) Show SMILES OCc1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C17H14BrN3O/c1-2-9-3-4-10-8-12-15(11(10)7-9)20-17(19)21-16(12)13-5-6-14(18)22-13/h3-7H,2,8H2,1H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399320 (CHEMBL2180869) Show SMILES O=C(Nc1ccn[nH]1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C16H17N5O2/c22-15-10-4-3-5-11(14(10)12-6-1-2-9-21(12)15)18-16(23)19-13-7-8-17-20-13/h3-5,7-8,12H,1-2,6,9H2,(H3,17,18,19,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) Show SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/P25 using myelin basic protein substrate				Eur J Med Chem 57: 225-33 (2012) Article DOI: 10.1016/j.ejmech.2012.09.001 BindingDB Entry DOI: 10.7270/Q2RF5W4C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50028097 (CHEMBL3338888) Show SMILES COc1ccc2[nH]c3c(c(n[nH]c3=O)-c3ccco3)c2c1 Show InChI InChI=1S/C15H11N3O3/c1-20-8-4-5-10-9(7-8)12-13(11-3-2-6-21-11)17-18-15(19)14(12)16-10/h2-7,16H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				Bioorg Med Chem Lett 24: 5037-40 (2014) Article DOI: 10.1016/j.bmcl.2014.09.017 BindingDB Entry DOI: 10.7270/Q27H1M51
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399308 (CHEMBL2180856) Show SMILES Fc1cnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c(F)c1 Show InChI InChI=1S/C18H16F2N4O2/c19-10-8-12(20)16(21-9-10)23-18(26)22-13-5-3-4-11-15(13)14-6-1-2-7-24(14)17(11)25/h3-5,8-9,14H,1-2,6-7H2,(H2,21,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50391185 (CHEMBL2088663) Show SMILES Cc1n[nH]c(=O)c2n(Cc3cccc(c3)C#N)c3ccc(Br)cc3c12 Show InChI InChI=1S/C19H13BrN4O/c1-11-17-15-8-14(20)5-6-16(15)24(18(17)19(25)23-22-11)10-13-4-2-3-12(7-13)9-21/h2-8H,10H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of PI3K p110gamma by fluorescence based immunoassay				Eur J Med Chem 57: 225-33 (2012) Article DOI: 10.1016/j.ejmech.2012.09.001 BindingDB Entry DOI: 10.7270/Q2RF5W4C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161350 (CHEMBL3787093) Show SMILES COC(=O)c1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C18H15N3/c1-11-7-8-13-10-15-16(12-5-3-2-4-6-12)20-18(19)21-17(15)14(13)9-11/h2-9H,10H2,1H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161397 (CHEMBL3787135) Show SMILES O=C(Nc1ccc2ccccc2n1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C22H20N4O2/c27-21-15-7-5-9-17(20(15)18-10-3-4-13-26(18)21)24-22(28)25-19-12-11-14-6-1-2-8-16(14)23-19/h1-2,5-9,11-12,18H,3-4,10,13H2,(H2,23,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161340 (CHEMBL3787081) Show SMILES COCc1ccnc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c1 Show InChI InChI=1S/C17H14N4/c1-10-5-6-11-9-13-15(12(11)8-10)20-17(18)21-16(13)14-4-2-3-7-19-14/h2-8H,9H2,1H3,(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399323 (CHEMBL2180866) Show SMILES O=C(Nc1cscn1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C16H16N4O2S/c21-15-10-4-3-5-11(14(10)12-6-1-2-7-20(12)15)18-16(22)19-13-8-23-9-17-13/h3-5,8-9,12H,1-2,6-7H2,(H2,18,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399319 (CHEMBL2180870) Show SMILES Cn1ccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C17H19N5O2/c1-21-10-8-14(20-21)19-17(24)18-12-6-4-5-11-15(12)13-7-2-3-9-22(13)16(11)23/h4-6,8,10,13H,2-3,7,9H2,1H3,(H2,18,19,20,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399322 (CHEMBL2180867) Show SMILES Cc1nc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)cs1 Show InChI InChI=1S/C17H18N4O2S/c1-10-18-14(9-24-10)20-17(23)19-12-6-4-5-11-15(12)13-7-2-3-8-21(13)16(11)22/h4-6,9,13H,2-3,7-8H2,1H3,(H2,19,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399306 (CHEMBL2180858) Show SMILES COc1cccnc1NC(=O)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C19H20N4O3/c1-26-15-9-5-10-20-17(15)22-19(25)21-13-7-4-6-12-16(13)14-8-2-3-11-23(14)18(12)24/h4-7,9-10,14H,2-3,8,11H2,1H3,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50028088 (CHEMBL3338893) Show SMILES COc1ccc(Nc2cc(n[nH]c2=O)-c2ccncc2)cc1 Show InChI InChI=1S/C16H14N4O2/c1-22-13-4-2-12(3-5-13)18-15-10-14(19-20-16(15)21)11-6-8-17-9-7-11/h2-10H,1H3,(H,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				Bioorg Med Chem Lett 24: 5037-40 (2014) Article DOI: 10.1016/j.bmcl.2014.09.017 BindingDB Entry DOI: 10.7270/Q27H1M51
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399314 (CHEMBL2180850) Show SMILES Oc1cccc2ccc(NC(=O)Nc3cccc4C(=O)N5CCCCC5c34)nc12 Show InChI InChI=1S/C22H20N4O3/c27-17-9-3-5-13-10-11-18(24-20(13)17)25-22(29)23-15-7-4-6-14-19(15)16-8-1-2-12-26(16)21(14)28/h3-7,9-11,16,27H,1-2,8,12H2,(H2,23,24,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161355 (CHEMBL3786745) Show SMILES O=C(Nc1cccc(CN2CCCCC2)n1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C19H17BrN4O/c20-16-6-5-15(25-16)18-14-9-11-3-4-12(24-7-1-2-8-24)10-13(11)17(14)22-19(21)23-18/h3-6,10H,1-2,7-9H2,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161358 (CHEMBL3787033) Show SMILES Cc1cncc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C19H18BrN3O/c1-19(2,3)11-5-4-10-8-13-16(12(10)9-11)22-18(21)23-17(13)14-6-7-15(20)24-14/h4-7,9H,8H2,1-3H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50161352 (CHEMBL3785804) Show SMILES COCc1cccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)n1 Show InChI InChI=1S/C17H13N3O/c18-17-19-14(10-6-2-1-3-7-10)13-15(20-17)11-8-4-5-9-12(11)16(13)21/h1-9,16,21H,(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate				Eur J Med Chem 115: 311-25 (2016) Article DOI: 10.1016/j.ejmech.2016.02.072 BindingDB Entry DOI: 10.7270/Q2JM2CHT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399302 (CHEMBL2180845) Show SMILES Oc1ccc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)nc1 Show InChI InChI=1S/C18H18N4O3/c23-11-7-8-15(19-10-11)21-18(25)20-13-5-3-4-12-16(13)14-6-1-2-9-22(14)17(12)24/h3-5,7-8,10,14,23H,1-2,6,9H2,(H2,19,20,21,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50028101 (CHEMBL3338886) Show SMILES COc1ccc(cc1)-c1n[nH]c(=O)c2[nH]c3ccc(OC)cc3c12 Show InChI InChI=1S/C18H15N3O3/c1-23-11-5-3-10(4-6-11)16-15-13-9-12(24-2)7-8-14(13)19-17(15)18(22)21-20-16/h3-9,19H,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				Bioorg Med Chem Lett 24: 5037-40 (2014) Article DOI: 10.1016/j.bmcl.2014.09.017 BindingDB Entry DOI: 10.7270/Q27H1M51
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50399317 (CHEMBL2180847) Show SMILES O=C(Nc1cc(on1)-c1ccccc1)Nc1cccc2C(=O)N3CCCCC3c12 Show InChI InChI=1S/C22H20N4O3/c27-21-15-9-6-10-16(20(15)17-11-4-5-12-26(17)21)23-22(28)24-19-13-18(29-25-19)14-7-2-1-3-8-14/h1-3,6-10,13,17H,4-5,11-12H2,(H2,23,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting				J Med Chem 55: 9589-606 (2012) Article DOI: 10.1021/jm3008536 BindingDB Entry DOI: 10.7270/Q28S4R2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50391187 (CHEMBL2088665) Show SMILES COc1cccc(Cn2c3ccc(Br)cc3c3c(C)n[nH]c(=O)c23)c1 Show InChI InChI=1S/C19H16BrN3O2/c1-11-17-15-9-13(20)6-7-16(15)23(18(17)19(24)22-21-11)10-12-4-3-5-14(8-12)25-2/h3-9H,10H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassay				Eur J Med Chem 57: 225-33 (2012) Article DOI: 10.1016/j.ejmech.2012.09.001 BindingDB Entry DOI: 10.7270/Q2RF5W4C
					More data for this Ligand-Target Pair

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