Compile Data Set for Download or QSAR

Found 1336 hits with Last Name = 'sano' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50349866 (CHEMBL160296 | CHEMBL1813590 | UNC10108016 | US915...) Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C24H31N3O3/c1-29-23-7-3-2-6-22(23)27-15-13-26(14-16-27)12-4-5-17-30-20-10-8-19-9-11-24(28)25-21(19)18-20/h2-3,6-8,10,18H,4-5,9,11-17H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50395587 (CHEMBL2165126 | UNC10000006 | US9156822, 2) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT1A receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50395578 (CHEMBL2165137 | UNC10099993 | US9156822, 21) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT2C receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50395578 (CHEMBL2165137 | UNC10099993 | US9156822, 21) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT1A receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50395587 (CHEMBL2165126 | UNC10000006 | US9156822, 2) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT2C receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50395578 (CHEMBL2165137 | UNC10099993 | US9156822, 21) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT2B receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50395587 (CHEMBL2165126 | UNC10000006 | US9156822, 2) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT2B receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50395578 (CHEMBL2165137 | UNC10099993 | US9156822, 21) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT2A receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50395587 (CHEMBL2165126 | UNC10000006 | US9156822, 2) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to 5-HT2A receptor				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50281817 (CHEMBL1712377) Show SMILES O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1nccs1 Show InChI InChI=1S/C17H22N4OS/c22-16(19-17-18-7-13-23-17)6-8-20-9-11-21(12-10-20)14-15-4-2-1-3-5-15/h1-5,7,13H,6,8-12,14H2,(H,18,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human HRH1 expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395569 (CHEMBL2165119 | UNC10099975 | US9156822, 3 or UNC9...) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl Show InChI InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395567 (CHEMBL443034) Show SMILES CCOc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C25H33N3O3/c1-2-30-24-8-4-3-7-23(24)28-16-14-27(15-17-28)13-5-6-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h3-4,7-9,11,19H,2,5-6,10,12-18H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395562 (CHEMBL160921) Show SMILES O=C1CCc2ccc(OCCCCN3CCN(CC3)c3ccccc3C#N)cc2N1 Show InChI InChI=1S/C24H28N4O2/c25-18-20-5-1-2-6-23(20)28-14-12-27(13-15-28)11-3-4-16-30-21-9-7-19-8-10-24(29)26-22(19)17-21/h1-2,5-7,9,17H,3-4,8,10-16H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395566 (CHEMBL2165121) Show SMILES CC(C)Oc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C26H35N3O3/c1-20(2)32-25-8-4-3-7-24(25)29-16-14-28(15-17-29)13-5-6-18-31-22-11-9-21-10-12-26(30)27-23(21)19-22/h3-4,7-9,11,19-20H,5-6,10,12-18H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395568 (CHEMBL2165120 | UNC10099978 | US9156822, 4) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C24H27Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-10,17H,1-2,4,11-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50343260 (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4n3)CC2)c1Cl Show InChI InChI=1S/C22H26Cl2N4O2/c23-17-4-3-5-18(21(17)24)28-13-11-27(12-14-28)10-1-2-15-30-20-9-7-16-6-8-19(29)25-22(16)26-20/h3-5,7,9H,1-2,6,8,10-15H2,(H,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395587 (CHEMBL2165126 | UNC10000006 | US9156822, 2) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-20-5-3-6-22(24(20)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-9-7-18-8-10-23(30)27-21(18)17-19/h3,5-7,9,17H,1-2,4,8,10-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395563 (CHEMBL157923) Show SMILES Clc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C23H28ClN3O2/c24-20-5-1-2-6-22(20)27-14-12-26(13-15-27)11-3-4-16-29-19-9-7-18-8-10-23(28)25-21(18)17-19/h1-2,5-7,9,17H,3-4,8,10-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395560 (CHEMBL2165122) Show SMILES FC(F)(F)c1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C24H28F3N3O2/c25-24(26,27)20-5-1-2-6-22(20)30-14-12-29(13-15-30)11-3-4-16-32-19-9-7-18-8-10-23(31)28-21(18)17-19/h1-2,5-7,9,17H,3-4,8,10-16H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395565 (CHEMBL160357) Show SMILES O=C1CCc2ccc(OCCCCN3CCN(CC3)c3ccccc3)cc2N1 Show InChI InChI=1S/C23H29N3O2/c27-23-11-9-19-8-10-21(18-22(19)24-23)28-17-5-4-12-25-13-15-26(16-14-25)20-6-2-1-3-7-20/h1-3,6-8,10,18H,4-5,9,11-17H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395564 (CHEMBL160630) Show SMILES Fc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C23H28FN3O2/c24-20-5-1-2-6-22(20)27-14-12-26(13-15-27)11-3-4-16-29-19-9-7-18-8-10-23(28)25-21(18)17-19/h1-2,5-7,9,17H,3-4,8,10-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395570 (CHEMBL2165118 | UNC10099983 | US9156822, 5) Show SMILES Clc1cccc(N2CCCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-20-4-1-5-21(22(20)25)28-12-2-10-27(13-14-28)11-3-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h1,4-7,16H,2-3,8-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395561 (CHEMBL346129) Show SMILES Cc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C24H31N3O2/c1-19-6-2-3-7-23(19)27-15-13-26(14-16-27)12-4-5-17-29-21-10-8-20-9-11-24(28)25-22(20)18-21/h2-3,6-8,10,18H,4-5,9,11-17H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395554 (CHEMBL161792) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C23H25Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-9,16H,1-2,10-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395557 (CHEMBL160744) Show SMILES Cc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1C Show InChI InChI=1S/C25H33N3O2/c1-19-6-5-7-24(20(19)2)28-15-13-27(14-16-28)12-3-4-17-30-22-10-8-21-9-11-25(29)26-23(21)18-22/h5-8,10,18H,3-4,9,11-17H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395573 (CHEMBL2165115 | UNC10108006 | US9156822, 24) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C22H25Cl2N3O2/c23-18-5-3-4-17(21(18)24)15-8-11-27(12-9-15)10-1-2-13-29-16-6-7-19-20(14-16)26-22(28)25-19/h3-7,14-15H,1-2,8-13H2,(H2,25,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395556 (CHEMBL2165125) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C24H28Cl2N2O2/c25-21-5-3-4-20(24(21)26)17-10-13-28(14-11-17)12-1-2-15-30-19-8-6-18-7-9-23(29)27-22(18)16-19/h3-6,8,16-17H,1-2,7,9-15H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395580 (CHEMBL2165135 | UNC10099990 | US9156822, 35) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C21H24Cl2N4O2/c22-16-4-3-5-19(20(16)23)27-11-9-26(10-12-27)8-1-2-13-29-15-6-7-17-18(14-15)25-21(28)24-17/h3-7,14H,1-2,8-13H2,(H2,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395579 (CHEMBL2165136 | UNC10099991 | US9156822, 36) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C21H23Cl2N3OS/c22-17-4-3-5-19(21(17)23)26-11-9-25(10-12-26)8-1-2-13-27-16-6-7-20-18(14-16)24-15-28-20/h3-7,14-15H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395574 (CHEMBL2165114 | UNC10099992 | US9156822, 7) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C22H25Cl2N3OS/c23-18-5-3-6-20(22(18)24)27-11-4-10-26(12-13-27)9-1-2-14-28-17-7-8-21-19(15-17)25-16-29-21/h3,5-8,15-16H,1-2,4,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395571 (CHEMBL2165117 | UNC10099981 | US10501452, Compound...) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H25Cl2N3O2/c23-19-3-1-4-20(21(19)24)27-12-10-26(11-13-27)9-2-14-29-17-6-5-16-7-8-25-22(28)18(16)15-17/h1,3-6,15H,2,7-14H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395582 (CHEMBL2165133 | UNC10000004 | US9156822, 25) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-20-4-3-5-21(22(20)25)28-13-11-27(12-14-28)10-1-2-15-30-18-7-6-17-8-9-26-23(29)19(17)16-18/h3-7,16H,1-2,8-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50281507 (CHEMBL4161436) Show SMILES C(N1CCCN(CC1)c1nccs1)c1coc(n1)-c1ccccc1 Show InChI InChI=1S/C18H20N4OS/c1-2-5-15(6-3-1)17-20-16(14-23-17)13-21-8-4-9-22(11-10-21)18-19-7-12-24-18/h1-3,5-7,12,14H,4,8-11,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human HRH1 expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395575 (CHEMBL2165140 | UNC10099996 | US9156822, 8) Show SMILES Clc1cccc(N2CCCN(CCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C21H23Cl2N3OS/c22-17-4-1-5-19(21(17)23)26-10-2-8-25(11-12-26)9-3-13-27-16-6-7-20-18(14-16)24-15-28-20/h1,4-7,14-15H,2-3,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395559 (CHEMBL2165123) Show SMILES CCOc1cccc(c1)N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C25H33N3O3/c1-2-30-22-7-5-6-21(18-22)28-15-13-27(14-16-28)12-3-4-17-31-23-10-8-20-9-11-25(29)26-24(20)19-23/h5-8,10,18-19H,2-4,9,11-17H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395555 (CHEMBL2165127) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C22H25Cl2N3O2/c23-18-3-1-4-20(22(18)24)27-12-10-26(11-13-27)9-2-14-29-17-7-5-16-6-8-21(28)25-19(16)15-17/h1,3-5,7,15H,2,6,8-14H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50281401 (CHEMBL4176490) Show SMILES Clc1cncc(NCCCN2CCN(CC2)c2ccccc2)n1 Show InChI InChI=1S/C17H22ClN5/c18-16-13-19-14-17(21-16)20-7-4-8-22-9-11-23(12-10-22)15-5-2-1-3-6-15/h1-3,5-6,13-14H,4,7-12H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395576 (CHEMBL2165139 | UNC10099995 | US9156822, 23) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C20H21Cl2N3OS/c21-16-3-1-4-18(20(16)22)25-10-8-24(9-11-25)7-2-12-26-15-5-6-19-17(13-15)23-14-27-19/h1,3-6,13-14H,2,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50281750 (CHEMBL4171171) Show SMILES Clc1cncc(NCCCCN2CCN(CC2)c2ccccc2)n1 Show InChI InChI=1S/C18H24ClN5/c19-17-14-20-15-18(22-17)21-8-4-5-9-23-10-12-24(13-11-23)16-6-2-1-3-7-16/h1-3,6-7,14-15H,4-5,8-13H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human HRH1 expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50281818 (CHEMBL3461530) Show SMILES Cc1[nH]ncc1C(=O)NCCCN1CCN(CC1)c1cccc(C)c1 Show InChI InChI=1S/C19H27N5O/c1-15-5-3-6-17(13-15)24-11-9-23(10-12-24)8-4-7-20-19(25)18-14-21-22-16(18)2/h3,5-6,13-14H,4,7-12H2,1-2H3,(H,20,25)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-HT2A (unknown origin) expressed in membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50281816 (CHEMBL4168691) Show SMILES N#Cc1c(CN2CCN(CCc3ccccc3)CC2)cn2ccccc12 Show InChI InChI=1S/C22H24N4/c23-16-21-20(18-26-10-5-4-8-22(21)26)17-25-14-12-24(13-15-25)11-9-19-6-2-1-3-7-19/h1-8,10,18H,9,11-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human HRH1 expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50281757 (CHEMBL4163265) Show SMILES Fc1ccccc1N1CCN(CCCNc2cncc(Cl)n2)CC1 Show InChI InChI=1S/C17H21ClFN5/c18-16-12-20-13-17(22-16)21-6-3-7-23-8-10-24(11-9-23)15-5-2-1-4-14(15)19/h1-2,4-5,12-13H,3,6-11H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human DRD2 after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50281401 (CHEMBL4176490) Show SMILES Clc1cncc(NCCCN2CCN(CC2)c2ccccc2)n1 Show InChI InChI=1S/C17H22ClN5/c18-16-13-19-14-17(21-16)20-7-4-8-22-9-11-23(12-10-22)15-5-2-1-3-6-15/h1-3,5-6,13-14H,4,7-12H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human HRH1 expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395578 (CHEMBL2165137 | UNC10099993 | US9156822, 21) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N2OS/c23-19-5-3-4-18(22(19)24)16-8-11-26(12-9-16)10-1-2-13-27-17-6-7-21-20(14-17)25-15-28-21/h3-7,14-16H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50281818 (CHEMBL3461530) Show SMILES Cc1[nH]ncc1C(=O)NCCCN1CCN(CC1)c1cccc(C)c1 Show InChI InChI=1S/C19H27N5O/c1-15-5-3-6-17(13-15)24-11-9-23(10-12-24)8-4-7-20-19(25)18-14-21-22-16(18)2/h3,5-6,13-14H,4,7-12H2,1-2H3,(H,20,25)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human HRH1 expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human))	BDBM15211 (CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...) Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 Show InChI InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	48	-42.5	n/a	n/a	n/a	n/a	n/a	n/a	30
Nagoya University School of Medicine					Assay Description Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...				J Biol Chem 265: 5267-72 (1990) BindingDB Entry DOI: 10.7270/Q2QR4VRF
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50281750 (CHEMBL4171171) Show SMILES Clc1cncc(NCCCCN2CCN(CC2)c2ccccc2)n1 Show InChI InChI=1S/C18H24ClN5/c19-17-14-20-15-18(22-17)21-8-4-5-9-23-10-12-24(13-11-23)16-6-2-1-3-7-16/h1-3,6-7,14-15H,4-5,8-13H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human DRD2 after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50395558 (CHEMBL2165124) Show SMILES CCOc1ccc(cc1)N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C25H33N3O3/c1-2-30-22-10-7-21(8-11-22)28-16-14-27(15-17-28)13-3-4-18-31-23-9-5-20-6-12-25(29)26-24(20)19-23/h5,7-11,19H,2-4,6,12-18H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting method				J Med Chem 55: 7141-53 (2012) Article DOI: 10.1021/jm300603y BindingDB Entry DOI: 10.7270/Q2JD4XXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50281749 (CHEMBL4175018) Show SMILES Cc1oc(nc1CN1CCN(CC1)[C@@H]1CCc2ccccc2C1)-c1ccco1 |r| Show InChI InChI=1S/C23H27N3O2/c1-17-21(24-23(28-17)22-7-4-14-27-22)16-25-10-12-26(13-11-25)20-9-8-18-5-2-3-6-19(18)15-20/h2-7,14,20H,8-13,15-16H2,1H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Francisco Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-HT2A (unknown origin) expressed in membranes after 90 mins by scintillation counting method				J Med Chem 61: 6830-6845 (2018) Article DOI: 10.1021/acs.jmedchem.8b00718 BindingDB Entry DOI: 10.7270/Q2BG2RJK
					More data for this Ligand-Target Pair

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