Compile Data Set for Download or QSAR

Found 132 hits with Last Name = 'stephensen' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146832 (1-(3,4-Dimethoxy-phenyl)-4-[4-(1-ethyl-propyl)-pip...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C21H32N2O4/c1-5-17(6-2)22-11-13-23(14-12-22)21(25)10-8-18(24)16-7-9-19(26-3)20(15-16)27-4/h7,9,15,17H,5-6,8,10-14H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146832 (1-(3,4-Dimethoxy-phenyl)-4-[4-(1-ethyl-propyl)-pip...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C21H32N2O4/c1-5-17(6-2)22-11-13-23(14-12-22)21(25)10-8-18(24)16-7-9-19(26-3)20(15-16)27-4/h7,9,15,17H,5-6,8,10-14H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370330 (CHEMBL1202893) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(F)c1 Show InChI InChI=1S/C20H29FN2O3/c1-4-16(5-2)22-10-12-23(13-11-22)20(25)9-7-18(24)15-6-8-19(26-3)17(21)14-15/h6,8,14,16H,4-5,7,9-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146836 (1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-propyl)-pip...) Show SMILES CCC(C)(C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H27ClN2O2/c1-4-19(2,3)22-13-11-21(12-14-22)18(24)10-9-17(23)15-5-7-16(20)8-6-15/h5-8H,4,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) Show SMILES NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| Show InChI InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) Show SMILES NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| Show InChI InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370328 (CHEMBL1202892) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCOc1ccc(cc1)C#N Show InChI InChI=1S/C19H27N3O2/c1-3-17(4-2)21-10-12-22(13-11-21)19(23)9-14-24-18-7-5-16(15-20)6-8-18/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146838 (1-(4-Chloro-phenyl)-4-[4-(1-ethyl-propyl)-piperazi...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H27ClN2O2/c1-3-17(4-2)21-11-13-22(14-12-21)19(24)10-9-18(23)15-5-7-16(20)8-6-15/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370331 (CHEMBL1202896) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)N(C)C Show InChI InChI=1S/C19H31N3O/c1-5-17(6-2)21-11-13-22(14-12-21)19(23)15-16-7-9-18(10-8-16)20(3)4/h7-10,17H,5-6,11-15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159113 (2-(4-Cyclopropyl-piperazin-1-yl)-6-pyrazol-1-yl-qu...) Show SMILES C1CC1N1CCN(CC1)c1ccc2cc(ccc2n1)-n1cccn1 Show InChI InChI=1S/C19H21N5/c1-8-20-24(9-1)17-5-6-18-15(14-17)2-7-19(21-18)23-12-10-22(11-13-23)16-3-4-16/h1-2,5-9,14,16H,3-4,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146835 (1-(4-Chloro-phenyl)-4-(4-cyclopentyl-piperazin-1-y...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCC1 Show InChI InChI=1S/C19H25ClN2O2/c20-16-7-5-15(6-8-16)18(23)9-10-19(24)22-13-11-21(12-14-22)17-3-1-2-4-17/h5-8,17H,1-4,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146826 (1-(4-Chloro-phenyl)-4-(4-cyclobutyl-piperazin-1-yl...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCC1 Show InChI InChI=1S/C18H23ClN2O2/c19-15-6-4-14(5-7-15)17(22)8-9-18(23)21-12-10-20(11-13-21)16-2-1-3-16/h4-7,16H,1-3,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146840 (3-(4-Chloro-phenoxy)-1-[4-(1-ethyl-propyl)-piperaz...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCOc1ccc(Cl)cc1 Show InChI InChI=1S/C18H27ClN2O2/c1-3-16(4-2)20-10-12-21(13-11-20)18(22)9-14-23-17-7-5-15(19)6-8-17/h5-8,16H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370336 (CHEMBL1202903) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H27F3N2O2/c1-3-17(4-2)24-11-13-25(14-12-24)19(27)10-9-18(26)15-5-7-16(8-6-15)20(21,22)23/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370338 (CHEMBL1202904) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(F)cc1 Show InChI InChI=1S/C19H27FN2O2/c1-3-17(4-2)21-11-13-22(14-12-21)19(24)10-9-18(23)15-5-7-16(20)8-6-15/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159114 (CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...) Show SMILES O=C(C1CC1)c1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C20H23N3O/c24-20(14-1-2-14)16-3-7-18-15(13-16)4-8-19(21-18)23-11-9-22(10-12-23)17-5-6-17/h3-4,7-8,13-14,17H,1-2,5-6,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50120543 (7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...) Show SMILES Cc1ccn2cc(nc2c1)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C22H27N3O/c1-18-10-14-25-17-21(23-22(25)16-18)19-6-8-20(9-7-19)26-15-5-13-24-11-3-2-4-12-24/h6-10,14,16-17H,2-5,11-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370327 (CHEMBL1202901) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H25F3N2O/c1-3-16(4-2)22-9-11-23(12-10-22)17(24)13-14-5-7-15(8-6-14)18(19,20)21/h5-8,16H,3-4,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370326 (CHEMBL1202900) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C18H25F3N2O2/c1-3-15(4-2)22-9-11-23(12-10-22)17(24)13-14-5-7-16(8-6-14)25-18(19,20)21/h5-8,15H,3-4,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22904 ((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...) Show SMILES C[C@@H](N)Cc1cnc[nH]1 |r| Show InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370329 (CHEMBL1202894) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C20H27F3N2O3/c1-3-16(4-2)24-11-13-25(14-12-24)19(27)10-9-18(26)15-5-7-17(8-6-15)28-20(21,22)23/h5-8,16H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370339 (CHEMBL1202899) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H30N2O/c1-3-22(4-2)24-14-16-25(17-15-24)23(26)18-19-10-12-21(13-11-19)20-8-6-5-7-9-20/h5-13,22H,3-4,14-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159116 (2-[4-(1-Ethyl-propyl)-piperazin-1-yl]-quinoline | ...) Show SMILES CCC(CC)N1CCN(CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C18H25N3/c1-3-16(4-2)20-11-13-21(14-12-20)18-10-9-15-7-5-6-8-17(15)19-18/h5-10,16H,3-4,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159122 (2-(4-Cyclopropyl-piperazin-1-yl)-6-methoxy-quinoli...) Show SMILES COc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C17H21N3O/c1-21-15-5-6-16-13(12-15)2-7-17(18-16)20-10-8-19(9-11-20)14-3-4-14/h2,5-7,12,14H,3-4,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146843 (1-(4-Chloro-phenyl)-4-(4-cyclohexyl-piperazin-1-yl...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C20H27ClN2O2/c21-17-8-6-16(7-9-17)19(24)10-11-20(25)23-14-12-22(13-15-23)18-4-2-1-3-5-18/h6-9,18H,1-5,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146839 (1-(4-Chloro-phenyl)-4-(4-isopropyl-piperazin-1-yl)...) Show SMILES CC(C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H23ClN2O2/c1-13(2)19-9-11-20(12-10-19)17(22)8-7-16(21)14-3-5-15(18)6-4-14/h3-6,13H,7-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159121 (2-(4-Cyclopropyl-piperazin-1-yl)-quinoline-6-carbo...) Show SMILES N#Cc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C17H18N4/c18-12-13-1-5-16-14(11-13)2-6-17(19-16)21-9-7-20(8-10-21)15-3-4-15/h1-2,5-6,11,15H,3-4,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159120 (2-(4-Propyl-piperazin-1-yl)-quinoline | CHEMBL1804...) Show SMILES CCN1CCN(CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C15H19N3/c1-2-17-9-11-18(12-10-17)15-8-7-13-5-3-4-6-14(13)16-15/h3-8H,2,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159108 (2-(4-Isopropyl-piperazin-1-yl)-quinoline | CHEMBL3...) Show SMILES CC(C)N1CCN(CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C16H21N3/c1-13(2)18-9-11-19(12-10-18)16-8-7-14-5-3-4-6-15(14)17-16/h3-8,13H,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146820 (1-(4-Chloro-phenyl)-4-(4-cyclopropylmethyl-piperaz...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC2CC2)CC1 Show InChI InChI=1S/C18H23ClN2O2/c19-16-5-3-15(4-6-16)17(22)7-8-18(23)21-11-9-20(10-12-21)13-14-1-2-14/h3-6,14H,1-2,7-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370337 (CHEMBL1202902) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H27F3N2O/c1-3-17(4-2)23-11-13-24(14-12-23)18(25)10-7-15-5-8-16(9-6-15)19(20,21)22/h5-6,8-9,17H,3-4,7,10-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146818 (1-(4-Chloro-phenyl)-4-[4-(tetrahydro-pyran-4-yl)-p...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCOCC1 Show InChI InChI=1S/C19H25ClN2O3/c20-16-3-1-15(2-4-16)18(23)5-6-19(24)22-11-9-21(10-12-22)17-7-13-25-14-8-17/h1-4,17H,5-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080367 ((R)-1-{2-[(Z)-2-(2-Chloro-phenyl)-2-phenyl-vinylox...) Show SMILES OC(=O)[C@@H]1CCCN(CCO\C=C(\c2ccccc2)c2ccccc2Cl)C1 Show InChI InChI=1S/C22H24ClNO3/c23-21-11-5-4-10-19(21)20(17-7-2-1-3-8-17)16-27-14-13-24-12-6-9-18(15-24)22(25)26/h1-5,7-8,10-11,16,18H,6,9,12-15H2,(H,25,26)/b20-16-/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080358 (1-{2-[2,2-Bis-(2-chloro-phenyl)-vinyloxy]-ethyl}-1...) Show SMILES [#8]-[#6](=O)-[#6]-1=[#6]-[#6]-[#6]-[#7](-[#6]-[#6]-[#8]\[#6]=[#6](\c2ccccc2Cl)-c2ccccc2Cl)-[#6]-1 |t:3| Show InChI InChI=1S/C22H21Cl2NO3/c23-20-9-3-1-7-17(20)19(18-8-2-4-10-21(18)24)15-28-13-12-25-11-5-6-16(14-25)22(26)27/h1-4,6-10,15H,5,11-14H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080382 ((R)-1-{2-[(Z)-2-(2-Chloro-phenyl)-2-o-tolyl-vinylo...) Show SMILES Cc1ccccc1\C(=C\OCCN1CCC[C@H](C1)C(O)=O)c1ccccc1Cl Show InChI InChI=1S/C23H26ClNO3/c1-17-7-2-3-9-19(17)21(20-10-4-5-11-22(20)24)16-28-14-13-25-12-6-8-18(15-25)23(26)27/h2-5,7,9-11,16,18H,6,8,12-15H2,1H3,(H,26,27)/b21-16-/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159109 (2-(4-Cyclopropyl-piperazin-1-yl)-quinoline | CHEMB...) Show SMILES C1CC1N1CCN(CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C16H19N3/c1-2-4-15-13(3-1)5-8-16(17-15)19-11-9-18(10-12-19)14-6-7-14/h1-5,8,14H,6-7,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146829 (1-(4-Chloro-phenyl)-4-(4-cyclopropyl-piperazin-1-y...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C17H21ClN2O2/c18-14-3-1-13(2-4-14)16(21)7-8-17(22)20-11-9-19(10-12-20)15-5-6-15/h1-4,15H,5-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080337 ((R)-1-{2-[2,2-Bis-(3-methyl-thiophen-2-yl)-vinylox...) Show SMILES [#6]-c1ccsc1\[#6](=[#6]/[#8]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H](-[#6]-1)-[#6](-[#8])=O)-c1sccc1-[#6] Show InChI InChI=1S/C20H25NO3S2/c1-14-5-10-25-18(14)17(19-15(2)6-11-26-19)13-24-9-8-21-7-3-4-16(12-21)20(22)23/h5-6,10-11,13,16H,3-4,7-9,12H2,1-2H3,(H,22,23)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080376 ((R)-1-{2-[(E)-2-(3-Methyl-thiophen-2-yl)-2-o-tolyl...) Show SMILES Cc1ccsc1\C(=C\OCCN1CCC[C@H](C1)C(O)=O)c1ccccc1C Show InChI InChI=1S/C22H27NO3S/c1-16-6-3-4-8-19(16)20(21-17(2)9-13-27-21)15-26-12-11-23-10-5-7-18(14-23)22(24)25/h3-4,6,8-9,13,15,18H,5,7,10-12,14H2,1-2H3,(H,24,25)/b20-15+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159111 ((R)-2-Quinolin-2-yl-octahydro-pyrido[1,2-a]pyrazin...) Show SMILES C1CCN2CCN(C[C@H]2C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C17H21N3/c1-2-7-16-14(5-1)8-9-17(18-16)20-12-11-19-10-4-3-6-15(19)13-20/h1-2,5,7-9,15H,3-4,6,10-13H2/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080327 (1-{2-[(Z)-2-(2-Fluoro-phenyl)-2-o-tolyl-vinyloxy]-...) Show SMILES Cc1ccccc1\C(=C\OCCN1CCC=C(C1)C(O)=O)c1ccccc1F |c:16| Show InChI InChI=1S/C23H24FNO3/c1-17-7-2-3-9-19(17)21(20-10-4-5-11-22(20)24)16-28-14-13-25-12-6-8-18(15-25)23(26)27/h2-5,7-11,16H,6,12-15H2,1H3,(H,26,27)/b21-16-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080335 ((R)-1-[2-(2,2-Di-o-tolyl-vinyloxy)-ethyl]-piperidi...) Show SMILES [#6]-c1ccccc1\[#6](=[#6]/[#8]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H](-[#6]-1)-[#6](-[#8])=O)-c1ccccc1-[#6] Show InChI InChI=1S/C24H29NO3/c1-18-8-3-5-11-21(18)23(22-12-6-4-9-19(22)2)17-28-15-14-25-13-7-10-20(16-25)24(26)27/h3-6,8-9,11-12,17,20H,7,10,13-16H2,1-2H3,(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080375 ((R)-1-[2-((E)-2-Phenyl-2-o-tolyl-vinyloxy)-ethyl]-...) Show SMILES Cc1ccccc1\C(=C\OCCN1CCC[C@H](C1)C(O)=O)c1ccccc1 Show InChI InChI=1S/C23H27NO3/c1-18-8-5-6-12-21(18)22(19-9-3-2-4-10-19)17-27-15-14-24-13-7-11-20(16-24)23(25)26/h2-6,8-10,12,17,20H,7,11,13-16H2,1H3,(H,25,26)/b22-17+/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370334 (CHEMBL1202897) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(C)=O Show InChI InChI=1S/C19H28N2O2/c1-4-18(5-2)20-10-12-21(13-11-20)19(23)14-16-6-8-17(9-7-16)15(3)22/h6-9,18H,4-5,10-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159118 (6-Chloro-2-(4-cyclopropyl-piperazin-1-yl)-quinolin...) Show SMILES Clc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C16H18ClN3/c17-13-2-5-15-12(11-13)1-6-16(18-15)20-9-7-19(8-10-20)14-3-4-14/h1-2,5-6,11,14H,3-4,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080368 (1-[2-(2,2-Di-o-tolyl-vinyloxy)-ethyl]-1,2,5,6-tetr...) Show SMILES [#6]-c1ccccc1\[#6](=[#6]/[#8]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]=[#6](-[#6]-1)-[#6](-[#8])=O)-c1ccccc1-[#6] |c:16| Show InChI InChI=1S/C24H27NO3/c1-18-8-3-5-11-21(18)23(22-12-6-4-9-19(22)2)17-28-15-14-25-13-7-10-20(16-25)24(26)27/h3-6,8-12,17H,7,13-16H2,1-2H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM50080388 ((R)-1-{2-[(E)-2-(3-Fluoro-phenyl)-2-o-tolyl-vinylo...) Show SMILES Cc1ccccc1\C(=C\OCCN1CCC[C@H](C1)C(O)=O)c1cccc(F)c1 Show InChI InChI=1S/C23H26FNO3/c1-17-6-2-3-10-21(17)22(18-7-4-9-20(24)14-18)16-28-13-12-25-11-5-8-19(15-25)23(26)27/h2-4,6-7,9-10,14,16,19H,5,8,11-13,15H2,1H3,(H,26,27)/b22-16+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomes				J Med Chem 42: 3447-62 (1999) Article DOI: 10.1021/jm981027k BindingDB Entry DOI: 10.7270/Q2057GMV
					More data for this Ligand-Target Pair

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