Compile Data Set for Download or QSAR

Found 53 hits with Last Name = 'welch' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13531 (4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15744 (1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1F)C(=O)c1cccc(c1)-c1cccnc1 Show InChI InChI=1S/C21H14F2N4O/c22-16-6-7-19(18(23)10-16)27-21(24)17(12-26-27)20(28)14-4-1-3-13(9-14)15-5-2-8-25-11-15/h1-12H,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15749 (1-[2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(CCC2(O)CCCC2)c1 Show InChI InChI=1S/C23H24FN3O2/c24-18-6-8-19(9-7-18)27-22(25)20(15-26-27)21(28)17-5-3-4-16(14-17)10-13-23(29)11-1-2-12-23/h3-9,14-15,29H,1-2,10-13,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15743 (1-(2,4-difluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1F)C(=O)c1cccc(c1)-c1ccncc1 Show InChI InChI=1S/C21H14F2N4O/c22-16-4-5-19(18(23)11-16)27-21(24)17(12-26-27)20(28)15-3-1-2-14(10-15)13-6-8-25-9-7-13/h1-12H,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15745 (1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yloxy)phen...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1F)C(=O)c1cccc(Oc2cccnc2)c1 Show InChI InChI=1S/C21H14F2N4O2/c22-14-6-7-19(18(23)10-14)27-21(24)17(12-26-27)20(28)13-3-1-4-15(9-13)29-16-5-2-8-25-11-16/h1-12H,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15750 (4-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES CC(C)(O)CCc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H22FN3O2/c1-21(2,27)11-10-14-4-3-5-15(12-14)19(26)18-13-24-25(20(18)23)17-8-6-16(22)7-9-17/h3-9,12-13,27H,10-11,23H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15754 ((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(OC[C@@H](O)CO)c1 |r| Show InChI InChI=1S/C19H18FN3O4/c20-13-4-6-14(7-5-13)23-19(21)17(9-22-23)18(26)12-2-1-3-16(8-12)27-11-15(25)10-24/h1-9,15,24-25H,10-11,21H2/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15740 (1-(4-fluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]carb...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)-c1cccnc1 Show InChI InChI=1S/C21H15FN4O/c22-17-6-8-18(9-7-17)26-21(23)19(13-25-26)20(27)15-4-1-3-14(11-15)16-5-2-10-24-12-16/h1-13H,23H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15748 (1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)p...) Show SMILES CS(=O)(=O)CCc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1 Show InChI InChI=1S/C19H18FN3O3S/c1-27(25,26)10-9-13-3-2-4-14(11-13)18(24)17-12-22-23(19(17)21)16-7-5-15(20)6-8-16/h2-8,11-12H,9-10,21H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15746 (2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(CCO)c1 Show InChI InChI=1S/C18H16FN3O2/c19-14-4-6-15(7-5-14)22-18(20)16(11-21-22)17(24)13-3-1-2-12(10-13)8-9-23/h1-7,10-11,23H,8-9,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15741 (1-(4-fluorophenyl)-4-{[4-(pyridin-3-yl)phenyl]carb...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C21H15FN4O/c22-17-7-9-18(10-8-17)26-21(23)19(13-25-26)20(27)15-5-3-14(4-6-15)16-2-1-11-24-12-16/h1-13H,23H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15718 ((5-Amino-1-O-tolyl-1H-pyrazol-4-yl)phenylmethanone...) Show SMILES Cc1ccccc1-n1ncc(C(=O)c2ccccc2)c1N Show InChI InChI=1S/C17H15N3O/c1-12-7-5-6-10-15(12)20-17(18)14(11-19-20)16(21)13-8-3-2-4-9-13/h2-11H,18H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15720 (4-benzoyl-1-(4-fluorophenyl)-1H-pyrazol-5-amine | ...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1ccccc1 Show InChI InChI=1S/C16H12FN3O/c17-12-6-8-13(9-7-12)20-16(18)14(10-19-20)15(21)11-4-2-1-3-5-11/h1-10H,18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15753 ((2R)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(OC[C@H](O)CO)c1 |r| Show InChI InChI=1S/C19H18FN3O4/c20-13-4-6-14(7-5-13)23-19(21)17(9-22-23)18(26)12-2-1-3-16(8-12)27-11-15(25)10-24/h1-9,15,24-25H,10-11,21H2/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15747 (2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(CCS(N)(=O)=O)c1 Show InChI InChI=1S/C18H17FN4O3S/c19-14-4-6-15(7-5-14)23-18(20)16(11-22-23)17(24)13-3-1-2-12(10-13)8-9-27(21,25)26/h1-7,10-11H,8-9,20H2,(H2,21,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15725 (1-(4-fluorophenyl)-4-({3-[2-(morpholin-4-yl)ethoxy...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(OCCN2CCOCC2)c1 Show InChI InChI=1S/C22H23FN4O3/c23-17-4-6-18(7-5-17)27-22(24)20(15-25-27)21(28)16-2-1-3-19(14-16)30-13-10-26-8-11-29-12-9-26/h1-7,14-15H,8-13,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15742 (1-(4-fluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]carb...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)-c1ccncc1 Show InChI InChI=1S/C21H15FN4O/c22-17-4-6-18(7-5-17)26-21(23)19(13-25-26)20(27)16-3-1-2-15(12-16)14-8-10-24-11-9-14/h1-13H,23H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15734 (1-(4-fluorophenyl)-4-({3-[3-(piperidin-1-yl)prop-1...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C#CCN1CCCCC1 Show InChI InChI=1S/C24H23FN4O/c25-20-9-11-21(12-10-20)29-24(26)22(17-27-29)23(30)19-8-4-6-18(16-19)7-5-15-28-13-2-1-3-14-28/h4,6,8-12,16-17H,1-3,13-15,26H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15728 (1-(4-fluorophenyl)-4-({3-[2-(4-methylpiperazin-1-y...) Show SMILES CN1CCN(CCc2cccc(c2)C(=O)c2cnn(c2N)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C23H26FN5O/c1-27-11-13-28(14-12-27)10-9-17-3-2-4-18(15-17)22(30)21-16-26-29(23(21)25)20-7-5-19(24)6-8-20/h2-8,15-16H,9-14,25H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15735 (1-(4-fluorophenyl)-4-({3-[3-(morpholin-4-yl)prop-1...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C#CCN1CCOCC1 Show InChI InChI=1S/C23H21FN4O2/c24-19-6-8-20(9-7-19)28-23(25)21(16-26-28)22(29)18-5-1-3-17(15-18)4-2-10-27-11-13-30-14-12-27/h1,3,5-9,15-16H,10-14,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15737 (1-(4-fluorophenyl)-4-({3-[3-(morpholin-4-yl)propyl...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(CCCN2CCOCC2)c1 Show InChI InChI=1S/C23H25FN4O2/c24-19-6-8-20(9-7-19)28-23(25)21(16-26-28)22(29)18-5-1-3-17(15-18)4-2-10-27-11-13-30-14-12-27/h1,3,5-9,15-16H,2,4,10-14,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15739 (1-(4-fluorophenyl)-4-({3-[2-(piperidin-1-yl)ethoxy...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(OCCN2CCCCC2)c1 Show InChI InChI=1S/C23H25FN4O2/c24-18-7-9-19(10-8-18)28-23(25)21(16-26-28)22(29)17-5-4-6-20(15-17)30-14-13-27-11-2-1-3-12-27/h4-10,15-16H,1-3,11-14,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15726 (1-(4-fluorophenyl)-4-{[3-(4-methylpiperazin-1-yl)p...) Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H22FN5O/c1-25-9-11-26(12-10-25)18-4-2-3-15(13-18)20(28)19-14-24-27(21(19)23)17-7-5-16(22)6-8-17/h2-8,13-14H,9-12,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15732 (4-({3-[3-(dimethylamino)prop-1-yn-1-yl]phenyl}carb...) Show SMILES CN(C)CC#Cc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H19FN4O/c1-25(2)12-4-6-15-5-3-7-16(13-15)20(27)19-14-24-26(21(19)23)18-10-8-17(22)9-11-18/h3,5,7-11,13-14H,12,23H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15714 ((5-Amino-1-phenyl-1H-pyrazol-4-yl)phenylmethanone ...) Show SMILES Nc1c(cnn1-c1ccccc1)C(=O)c1ccccc1 Show InChI InChI=1S/C16H13N3O/c17-16-14(15(20)12-7-3-1-4-8-12)11-18-19(16)13-9-5-2-6-10-13/h1-11H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15727 (4-{[3-(2-aminoethyl)phenyl]carbonyl}-1-(4-fluoroph...) Show SMILES NCCc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN4O/c19-14-4-6-15(7-5-14)23-18(21)16(11-22-23)17(24)13-3-1-2-12(10-13)8-9-20/h1-7,10-11H,8-9,20-21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15733 (1-(4-fluorophenyl)-4-({3-[3-(4-methylpiperazin-1-y...) Show SMILES CN1CCN(CC#Cc2cccc(c2)C(=O)c2cnn(c2N)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C24H24FN5O/c1-28-12-14-29(15-13-28)11-3-5-18-4-2-6-19(16-18)23(31)22-17-27-30(24(22)26)21-9-7-20(25)8-10-21/h2,4,6-10,16-17H,11-15,26H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15722 (4-benzoyl-1-(2-fluorophenyl)-1H-pyrazol-5-amine | ...) Show SMILES Nc1c(cnn1-c1ccccc1F)C(=O)c1ccccc1 Show InChI InChI=1S/C16H12FN3O/c17-13-8-4-5-9-14(13)20-16(18)12(10-19-20)15(21)11-6-2-1-3-7-11/h1-10H,18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.86E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15736 (1-(4-fluorophenyl)-4-({4-[3-(morpholin-4-yl)prop-1...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1ccc(cc1)C#CCN1CCOCC1 Show InChI InChI=1S/C23H21FN4O2/c24-19-7-9-20(10-8-19)28-23(25)21(16-26-28)22(29)18-5-3-17(4-6-18)2-1-11-27-12-14-30-15-13-27/h3-10,16H,11-15,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15751 (1-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C(O)CO Show InChI InChI=1S/C18H16FN3O3/c19-13-4-6-14(7-5-13)22-18(20)15(9-21-22)17(25)12-3-1-2-11(8-12)16(24)10-23/h1-9,16,23-24H,10,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15731 (3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C#CCO Show InChI InChI=1S/C19H14FN3O2/c20-15-6-8-16(9-7-15)23-19(21)17(12-22-23)18(25)14-5-1-3-13(11-14)4-2-10-24/h1,3,5-9,11-12,24H,10,21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15729 (3-[5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbon...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C#N Show InChI InChI=1S/C17H11FN4O/c18-13-4-6-14(7-5-13)22-17(20)15(10-21-22)16(23)12-3-1-2-11(8-12)9-19/h1-8,10H,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15721 (4-benzoyl-1-(3-fluorophenyl)-1H-pyrazol-5-amine | ...) Show SMILES Nc1c(cnn1-c1cccc(F)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C16H12FN3O/c17-12-7-4-8-13(9-12)20-16(18)14(10-19-20)15(21)11-5-2-1-3-6-11/h1-10H,18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15723 (4-benzoyl-1-(4-methoxyphenyl)-1H-pyrazol-5-amine |...) Show SMILES COc1ccc(cc1)-n1ncc(C(=O)c2ccccc2)c1N Show InChI InChI=1S/C17H15N3O2/c1-22-14-9-7-13(8-10-14)20-17(18)15(11-19-20)16(21)12-5-3-2-4-6-12/h2-11H,18H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.06E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15730 (4-[5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbon...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1ccc(cc1)C#N Show InChI InChI=1S/C17H11FN4O/c18-13-5-7-14(8-6-13)22-17(20)15(10-21-22)16(23)12-3-1-11(9-19)2-4-12/h1-8,10H,20H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15724 (4-benzoyl-1-(2-methoxyphenyl)-1H-pyrazol-5-amine |...) Show SMILES COc1ccccc1-n1ncc(C(=O)c2ccccc2)c1N Show InChI InChI=1S/C17H15N3O2/c1-22-15-10-6-5-9-14(15)20-17(18)13(11-19-20)16(21)12-7-3-2-4-8-12/h2-11H,18H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.38E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15752 (2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(c1)C(O)(CO)CO Show InChI InChI=1S/C19H18FN3O4/c20-14-4-6-15(7-5-14)23-18(21)16(9-22-23)17(26)12-2-1-3-13(8-12)19(27,10-24)11-25/h1-9,24-25,27H,10-11,21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Concanavalin-A (Canavalia ensiformis)	BDBM50246207 (5-(hydrazinosulfonyl)isophthalic acid | CHEMBL4439...) Show SMILES NNS(=O)(=O)c1cc(cc(c1)C(O)=O)C(O)=O Show InChI InChI=1S/C8H8N2O6S/c9-10-17(15,16)6-2-4(7(11)12)1-5(3-6)8(13)14/h1-3,10H,9H2,(H,11,12)(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Southern University Curated by ChEMBL					Assay Description Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLA				Bioorg Med Chem Lett 18: 6573-5 (2008) Article DOI: 10.1016/j.bmcl.2008.09.095 BindingDB Entry DOI: 10.7270/Q2ZW1KRJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15738 (1-(4-fluorophenyl)-4-({4-[3-(morpholin-4-yl)propyl...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1ccc(CCCN2CCOCC2)cc1 Show InChI InChI=1S/C23H25FN4O2/c24-19-7-9-20(10-8-19)28-23(25)21(16-26-28)22(29)18-5-3-17(4-6-18)2-1-11-27-12-14-30-15-13-27/h3-10,16H,1-2,11-15,25H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Concanavalin-A (Canavalia ensiformis)	BDBM50246208 (2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...) Show SMILES OC(=O)C1CCCCC1c1c2ccc(O)c(O)c2oc2c(O)c(=O)ccc12 Show InChI InChI=1S/C20H18O7/c21-13-7-5-11-15(9-3-1-2-4-10(9)20(25)26)12-6-8-14(22)17(24)19(12)27-18(11)16(13)23/h5-10,21,23-24H,1-4H2,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Southern University Curated by ChEMBL					Assay Description Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLA				Bioorg Med Chem Lett 18: 6573-5 (2008) Article DOI: 10.1016/j.bmcl.2008.09.095 BindingDB Entry DOI: 10.7270/Q2ZW1KRJ
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM228816 (5-Cl-PZA) Show SMILES NC(=O)c1cnc(Cl)cn1 Show InChI InChI=1S/C5H4ClN3O/c6-4-2-8-3(1-9-4)5(7)10/h1-2H,(H2,7,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
University at Albany					Assay Description Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...				Chembiochem 18: 931-940 (2017) Article DOI: 10.1002/cbic.201600655 BindingDB Entry DOI: 10.7270/Q2CJ8CC2
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM228815 (5-MeO-PZA) Show SMILES COc1cnc(cn1)C(N)=O Show InChI InChI=1S/C6H7N3O2/c1-11-5-3-8-4(2-9-5)6(7)10/h2-3H,1H3,(H2,7,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University at Albany					Assay Description Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...				Chembiochem 18: 931-940 (2017) Article DOI: 10.1002/cbic.201600655 BindingDB Entry DOI: 10.7270/Q2CJ8CC2
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15717 ((5-Amino-1-phenyl-1H-pyrazol-4-yl)phenylmethanone ...) Show SMILES CO\N=C(/c1cnn(c1N)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C17H16N4O/c1-22-20-16(13-8-4-2-5-9-13)15-12-19-21(17(15)18)14-10-6-3-7-11-14/h2-12H,18H2,1H3/b20-16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15719 (4-benzoyl-1-(3-nitrophenyl)-1H-pyrazol-5-amine | [...) Show SMILES Nc1c(cnn1-c1cccc(c1)[N+]([O-])=O)C(=O)c1ccccc1 Show InChI InChI=1S/C16H12N4O3/c17-16-14(15(21)11-5-2-1-3-6-11)10-18-19(16)12-7-4-8-13(9-12)20(22)23/h1-10H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.42E+4	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15716 ((5-Hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)pheny...) Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C(=O)c1ccccc1 Show InChI InChI=1S/C17H14N2O2/c1-12-15(16(20)13-8-4-2-5-9-13)17(21)19(18-12)14-10-6-3-7-11-14/h2-11,18H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15715 (4-Benzoyl-2-phenyl-2H-pyrazole-3-carbonitrile | 4-...) Show SMILES O=C(c1cnn(c1C#N)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C17H11N3O/c18-11-16-15(17(21)13-7-3-1-4-8-13)12-19-20(16)14-9-5-2-6-10-14/h1-10,12H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM27507 (3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...) Show SMILES NC(=O)c1cccnc1 Show InChI InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
University at Albany					Assay Description Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...				Chembiochem 18: 931-940 (2017) Article DOI: 10.1002/cbic.201600655 BindingDB Entry DOI: 10.7270/Q2CJ8CC2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Concanavalin-A (Canavalia ensiformis)	BDBM50246209 (4-((2-hydroxypyridin-3-yl)diazenyl)benzenesulfonam...) Show SMILES NS(=O)(=O)c1ccc(cc1)N=Nc1ccc[nH]c1=O |w:11.12| Show InChI InChI=1S/C11H10N4O3S/c12-19(17,18)9-5-3-8(4-6-9)14-15-10-2-1-7-13-11(10)16/h1-7H,(H,13,16)(H2,12,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.34E+5	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Southern University Curated by ChEMBL					Assay Description Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLA				Bioorg Med Chem Lett 18: 6573-5 (2008) Article DOI: 10.1016/j.bmcl.2008.09.095 BindingDB Entry DOI: 10.7270/Q2ZW1KRJ
					More data for this Ligand-Target Pair
Concanavalin-A (Canavalia ensiformis)	BDBM50166886 (CHEMBL195368 | methyl alpha-D-mannoside) Show SMILES CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Southern University Curated by ChEMBL					Assay Description Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLA				Bioorg Med Chem Lett 18: 6573-5 (2008) Article DOI: 10.1016/j.bmcl.2008.09.095 BindingDB Entry DOI: 10.7270/Q2ZW1KRJ
					More data for this Ligand-Target Pair				3D Structure (docked)
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM228814 (PZA | Pyrazinamide | Tisamid | pyrazinecarboxamide) Show SMILES NC(=O)c1cnccn1 Show InChI InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
University at Albany					Assay Description Inhibitory constants (Ki) and IC50 values were determined under saturating substrate conditions by using a fluorimetric assay (components were purcha...				Chembiochem 18: 931-940 (2017) Article DOI: 10.1002/cbic.201600655 BindingDB Entry DOI: 10.7270/Q2CJ8CC2
					More data for this Ligand-Target Pair

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