BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 110 hits with Last Name = 'westlind-danielsson' and Initial = 'a'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM86708
PNG
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
PubMed
 0.240n/an/an/an/an/an/an/an/a



Preclinical R & D, Astra Arcus AB

Curated by PDSP Ki Database




J Pharmacol Exp Ther 283: 216-25 (1997)


BindingDB Entry DOI: 10.7270/Q22Z142T
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090771
PNG
((R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-et...)
Show SMILES CCCN(C(C)C)C1COc2cccc(C(C)=O)c2C1
Show InChI InChI=1S/C17H25NO2/c1-5-9-18(12(2)3)14-10-16-15(13(4)19)7-6-8-17(16)20-11-14/h6-8,12,14H,5,9-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 0.300n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090762
PNG
((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Show SMILES CCCN(C(C)C)C1COc2cccc(C(=O)OC)c2C1
Show InChI InChI=1S/C17H25NO3/c1-5-9-18(12(2)3)13-10-15-14(17(19)20-4)7-6-8-16(15)21-11-13/h6-8,12-13H,5,9-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 0.320n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090763
PNG
((R)-3-{[4-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-but...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(C(=O)NC)c2C1
Show InChI InChI=1S/C27H39N3O4/c1-3-13-29(20-16-22-21(26(33)28-2)9-8-10-23(22)34-19-20)14-6-7-15-30-24(31)17-27(18-25(30)32)11-4-5-12-27/h8-10,20H,3-7,11-19H2,1-2H3,(H,28,33)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.340n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090756
PNG
((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Show SMILES CCCN(C1CCCC1)C1COc2cccc(C(=O)OC)c2C1
Show InChI InChI=1S/C19H27NO3/c1-3-11-20(14-7-4-5-8-14)15-12-17-16(19(21)22-2)9-6-10-18(17)23-13-15/h6,9-10,14-15H,3-5,7-8,11-13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.410n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090764
PNG
((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Show SMILES CCCN(C(C)C)C1COc2cccc(C(N)=O)c2C1
Show InChI InChI=1S/C16H24N2O2/c1-4-8-18(11(2)3)12-9-14-13(16(17)19)6-5-7-15(14)20-10-12/h5-7,11-12H,4,8-10H2,1-3H3,(H2,17,19)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 0.480n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM85190
PNG
(CAS_3055171 | NAD-299 | NSC_3055171)
Show SMILES NC(=O)c1ccc(F)c2OCC(Cc12)N(C1CCC1)C1CCC1
Show InChI InChI=1S/C18H23FN2O2/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12/h7-8,11-13H,1-6,9-10H2,(H2,20,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Similars
PubMed
 0.590n/an/an/an/an/an/an/an/a



Preclinical R & D, Astra Arcus AB

Curated by PDSP Ki Database




J Pharmacol Exp Ther 283: 216-25 (1997)


BindingDB Entry DOI: 10.7270/Q22Z142T
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50030004
PNG
(1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(C(C)=O)c2C1
Show InChI InChI=1S/C18H27NO/c1-4-11-19(12-5-2)16-10-9-15-7-6-8-17(14(3)20)18(15)13-16/h6-8,16H,4-5,9-13H2,1-3H3/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.700n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053667
PNG
(CHEMBL552643 | Trifluoro-methanesulfonic acid (S)-...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@H]1CCc2c(F)ccc(OS(=O)(=O)C(F)(F)F)c2C1
Show InChI InChI=1S/C27H36F4N2O5S/c1-2-13-32(14-5-6-15-33-24(34)17-26(18-25(33)35)11-3-4-12-26)19-7-8-20-21(16-19)23(10-9-22(20)28)38-39(36,37)27(29,30)31/h9-10,19H,2-8,11-18H2,1H3/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.900n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053661
PNG
(8-{4-[((R)-5-Fluoro-8-furan-2-yl-1,2,3,4-tetrahydr...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@@H]1CCc2c(F)ccc(-c3ccco3)c2C1
Show InChI InChI=1S/C30H39FN2O3/c1-2-15-32(16-5-6-17-33-28(34)20-30(21-29(33)35)13-3-4-14-30)22-9-10-23-25(19-22)24(11-12-26(23)31)27-8-7-18-36-27/h7-8,11-12,18,22H,2-6,9-10,13-17,19-21H2,1H3/t22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.10n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50016777
PNG
(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.30n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053678
PNG
(((S)-8-Furan-2-yl-1,2,3,4-tetrahydro-naphthalen-2-...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(-c3ccco3)c2C1
Show InChI InChI=1S/C20H27NO/c1-3-12-21(13-4-2)17-11-10-16-7-5-8-18(19(16)15-17)20-9-6-14-22-20/h5-9,14,17H,3-4,10-13,15H2,1-2H3/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50030025
PNG
(1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(C(C)=O)c2C1
Show InChI InChI=1S/C18H27NO/c1-4-11-19(12-5-2)16-10-9-15-7-6-8-17(14(3)20)18(15)13-16/h6-8,16H,4-5,9-13H2,1-3H3/t16-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50011247
PNG
(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090772
PNG
((R)-3-(Isobutyl-propyl-amino)-chroman-5-carboxylic...)
Show SMILES CCCN(CC(C)C)C1COc2cccc(C(=O)NC)c2C1
Show InChI InChI=1S/C18H28N2O2/c1-5-9-20(11-13(2)3)14-10-16-15(18(21)19-4)7-6-8-17(16)22-12-14/h6-8,13-14H,5,9-12H2,1-4H3,(H,19,21)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 2.37n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090770
PNG
((R)-Isopropyl-(5-methoxy-chroman-3-yl)-propyl-amin...)
Show SMILES CCCN(C(C)C)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C16H25NO2/c1-5-9-17(12(2)3)13-10-14-15(18-4)7-6-8-16(14)19-11-13/h6-8,12-13H,5,9-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 3.10n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocam...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053668
PNG
(CHEMBL131547 | Dipropyl-((R)-8-trifluoromethanesul...)
Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(c2C1)S(=O)(=O)C(F)(F)F
Show InChI InChI=1S/C17H24F3NO2S/c1-3-10-21(11-4-2)14-9-8-13-6-5-7-16(15(13)12-14)24(22,23)17(18,19)20/h5-7,14H,3-4,8-12H2,1-2H3/t14-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.80n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053660
PNG
(8-{4-[((S)-5-Fluoro-8-methoxy-1,2,3,4-tetrahydro-n...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@H]1CCc2c(F)ccc(OC)c2C1
Show InChI InChI=1S/C27H39FN2O3/c1-3-14-29(20-8-9-21-22(17-20)24(33-2)11-10-23(21)28)15-6-7-16-30-25(31)18-27(19-26(30)32)12-4-5-13-27/h10-11,20H,3-9,12-19H2,1-2H3/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4.90n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053659
PNG
(CHEMBL441088 | Dipropyl-((S)-8-thiophen-2-yl-1,2,3...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(-c3cccs3)c2C1
Show InChI InChI=1S/C20H27NS/c1-3-12-21(13-4-2)17-11-10-16-7-5-8-18(19(16)15-17)20-9-6-14-22-20/h5-9,14,17H,3-4,10-13,15H2,1-2H3/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50013020
PNG
((R)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-na...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(O)c2C1
Show InChI InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 6.10n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053666
PNG
(1-((S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(C(C)=O)c2C1
Show InChI InChI=1S/C18H26FNO/c1-4-10-20(11-5-2)14-6-7-16-17(12-14)15(13(3)21)8-9-18(16)19/h8-9,14H,4-7,10-12H2,1-3H3/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 6.90n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053664
PNG
(1-((R)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(C(C)=O)c2C1
Show InChI InChI=1S/C18H26FNO/c1-4-10-20(11-5-2)14-6-7-16-17(12-14)15(13(3)21)8-9-18(16)19/h8-9,14H,4-7,10-12H2,1-3H3/t14-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 6.90n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053661
PNG
(8-{4-[((R)-5-Fluoro-8-furan-2-yl-1,2,3,4-tetrahydr...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@@H]1CCc2c(F)ccc(-c3ccco3)c2C1
Show InChI InChI=1S/C30H39FN2O3/c1-2-15-32(16-5-6-17-33-28(34)20-30(21-29(33)35)13-3-4-14-30)22-9-10-23-25(19-22)24(11-12-26(23)31)27-8-7-18-36-27/h7-8,11-12,18,22H,2-6,9-10,13-17,19-21H2,1H3/t22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 7.5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053662
PNG
(CHEMBL130922 | Dipropyl-((R)-8-thiophen-2-yl-1,2,3...)
Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(-c3cccs3)c2C1
Show InChI InChI=1S/C20H27NS/c1-3-12-21(13-4-2)17-11-10-16-7-5-8-18(19(16)15-17)20-9-6-14-22-20/h5-9,14,17H,3-4,10-13,15H2,1-2H3/t17-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 8.40n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053681
PNG
(((R)-8-Furan-2-yl-1,2,3,4-tetrahydro-naphthalen-2-...)
Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(-c3ccco3)c2C1
Show InChI InChI=1S/C20H27NO/c1-3-12-21(13-4-2)17-11-10-16-7-5-8-18(19(16)15-17)20-9-6-14-22-20/h5-9,14,17H,3-4,10-13,15H2,1-2H3/t17-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.30n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053684
PNG
(CHEMBL131501 | Dipropyl-((S)-8-trifluoromethanesul...)
Show SMILES CCCN(CCC)[C@H]1CCc2cccc(c2C1)S(=O)(=O)C(F)(F)F
Show InChI InChI=1S/C17H24F3NO2S/c1-3-10-21(11-4-2)14-9-8-13-6-5-7-16(15(13)12-14)24(22,23)17(18,19)20/h5-7,14H,3-4,8-12H2,1-2H3/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090771
PNG
((R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-et...)
Show SMILES CCCN(C(C)C)C1COc2cccc(C(C)=O)c2C1
Show InChI InChI=1S/C17H25NO2/c1-5-9-18(12(2)3)14-10-16-15(13(4)19)7-6-8-17(16)20-11-14/h6-8,12,14H,5,9-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 11.9n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053682
PNG
(8-{4-[((S)-8-Acetyl-5-fluoro-1,2,3,4-tetrahydro-na...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@H]1CCc2c(F)ccc(C(C)=O)c2C1
Show InChI InChI=1S/C28H39FN2O3/c1-3-14-30(21-8-9-23-24(17-21)22(20(2)32)10-11-25(23)29)15-6-7-16-31-26(33)18-28(19-27(31)34)12-4-5-13-28/h10-11,21H,3-9,12-19H2,1-2H3/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053666
PNG
(1-((S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(C(C)=O)c2C1
Show InChI InChI=1S/C18H26FNO/c1-4-10-20(11-5-2)14-6-7-16-17(12-14)15(13(3)21)8-9-18(16)19/h8-9,14H,4-7,10-12H2,1-3H3/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053666
PNG
(1-((S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(C(C)=O)c2C1
Show InChI InChI=1S/C18H26FNO/c1-4-10-20(11-5-2)14-6-7-16-17(12-14)15(13(3)21)8-9-18(16)19/h8-9,14H,4-7,10-12H2,1-3H3/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090759
PNG
((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Show SMILES CCCN(CCC)C1COc2cccc(C(=O)NC(C)C)c2C1
Show InChI InChI=1S/C19H30N2O2/c1-5-10-21(11-6-2)15-12-17-16(19(22)20-14(3)4)8-7-9-18(17)23-13-15/h7-9,14-15H,5-6,10-13H2,1-4H3,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 14n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50001859
PNG
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 15n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50030009
PNG
(CHEMBL88157 | Dipropyl-(1,2,3,4-tetrahydro-naphtha...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccccc2C1
Show InChI InChI=1S/C16H25N/c1-3-11-17(12-4-2)16-10-9-14-7-5-6-8-15(14)13-16/h5-8,16H,3-4,9-13H2,1-2H3/t16-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 17n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053680
PNG
(8-{4-[((S)-5-Fluoro-8-hydroxy-1,2,3,4-tetrahydro-n...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@H]1CCc2c(F)ccc(O)c2C1
Show InChI InChI=1S/C26H37FN2O3/c1-2-13-28(19-7-8-20-21(16-19)23(30)10-9-22(20)27)14-5-6-15-29-24(31)17-26(18-25(29)32)11-3-4-12-26/h9-10,19,30H,2-8,11-18H2,1H3/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 18n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090761
PNG
((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Show SMILES CCCN(C1CCCC1)C1COc2cccc(C(=O)NC)c2C1
Show InChI InChI=1S/C19H28N2O2/c1-3-11-21(14-7-4-5-8-14)15-12-17-16(19(22)20-2)9-6-10-18(17)23-13-15/h6,9-10,14-15H,3-5,7-8,11-13H2,1-2H3,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 18.5n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053673
PNG
(CHEMBL131776 | CHEMBL543660 | Trifluoro-methanesul...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(OS(=O)(=O)C(F)(F)F)c2C1
Show InChI InChI=1S/C17H23F4NO3S/c1-3-9-22(10-4-2)12-5-6-13-14(11-12)16(8-7-15(13)18)25-26(23,24)17(19,20)21/h7-8,12H,3-6,9-11H2,1-2H3/t12-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 19n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053673
PNG
(CHEMBL131776 | CHEMBL543660 | Trifluoro-methanesul...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(OS(=O)(=O)C(F)(F)F)c2C1
Show InChI InChI=1S/C17H23F4NO3S/c1-3-9-22(10-4-2)12-5-6-13-14(11-12)16(8-7-15(13)18)25-26(23,24)17(19,20)21/h7-8,12H,3-6,9-11H2,1-2H3/t12-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 19n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50013019
PNG
((S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydron...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1
Show InChI InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
 25n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053656
PNG
(((S)-5-Fluoro-8-furan-2-yl-1,2,3,4-tetrahydro-naph...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(-c3ccco3)c2C1
Show InChI InChI=1S/C20H26FNO/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 30n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053656
PNG
(((S)-5-Fluoro-8-furan-2-yl-1,2,3,4-tetrahydro-naph...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(-c3ccco3)c2C1
Show InChI InChI=1S/C20H26FNO/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 30n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053657
PNG
(((S)-5-Fluoro-8-thiophen-2-yl-1,2,3,4-tetrahydro-n...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(-c3cccs3)c2C1
Show InChI InChI=1S/C20H26FNS/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 33n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053657
PNG
(((S)-5-Fluoro-8-thiophen-2-yl-1,2,3,4-tetrahydro-n...)
Show SMILES CCCN(CCC)[C@H]1CCc2c(F)ccc(-c3cccs3)c2C1
Show InChI InChI=1S/C20H26FNS/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 33n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053658
PNG
(((R)-5-Fluoro-8-thiophen-2-yl-1,2,3,4-tetrahydro-n...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(-c3cccs3)c2C1
Show InChI InChI=1S/C20H26FNS/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 35n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053658
PNG
(((R)-5-Fluoro-8-thiophen-2-yl-1,2,3,4-tetrahydro-n...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(-c3cccs3)c2C1
Show InChI InChI=1S/C20H26FNS/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 35n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))		BDBM86708
PNG
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
PubMed
 45n/an/an/an/an/an/an/an/a



Preclinical R & D, Astra Arcus AB

Curated by PDSP Ki Database




J Pharmacol Exp Ther 283: 216-25 (1997)


BindingDB Entry DOI: 10.7270/Q22Z142T
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50030021
PNG
(CHEMBL88504 | Dipropyl-(1,2,3,4-tetrahydro-naphtha...)
Show SMILES CCCN(CCC)[C@H]1CCc2ccccc2C1
Show InChI InChI=1S/C16H25N/c1-3-11-17(12-4-2)16-10-9-14-7-5-6-8-15(14)13-16/h5-8,16H,3-4,9-13H2,1-2H3/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 56n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090759
PNG
((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Show SMILES CCCN(CCC)C1COc2cccc(C(=O)NC(C)C)c2C1
Show InChI InChI=1S/C19H30N2O2/c1-5-10-21(11-6-2)15-12-17-16(19(22)20-14(3)4)8-7-9-18(17)23-13-15/h7-9,14-15H,5-6,10-13H2,1-4H3,(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 64n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocam...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM86708
PNG
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
PubMed
 67n/an/an/an/an/an/an/an/a



Preclinical R & D, Astra Arcus AB

Curated by PDSP Ki Database




J Pharmacol Exp Ther 283: 216-25 (1997)


BindingDB Entry DOI: 10.7270/Q22Z142T
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM86708
PNG
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
PubMed
 79n/an/an/an/an/an/an/an/a



Preclinical R & D, Astra Arcus AB

Curated by PDSP Ki Database




J Pharmacol Exp Ther 283: 216-25 (1997)


BindingDB Entry DOI: 10.7270/Q22Z142T
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50053663
PNG
(((R)-5-Fluoro-8-furan-2-yl-1,2,3,4-tetrahydro-naph...)
Show SMILES CCCN(CCC)[C@@H]1CCc2c(F)ccc(-c3ccco3)c2C1
Show InChI InChI=1S/C20H26FNO/c1-3-11-22(12-4-2)15-7-8-16-18(14-15)17(9-10-19(16)21)20-6-5-13-23-20/h5-6,9-10,13,15H,3-4,7-8,11-12,14H2,1-2H3/t15-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 89n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligand

J Med Chem 39: 4036-43 (1996)


Article DOI: 10.1021/jm960329o
BindingDB Entry DOI: 10.7270/Q2XK8G6C
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 110 total )  |  Next  |  Last  >>
Jump to: