Compile Data Set for Download or QSAR

Found 119 hits Enz. Inhib. hit(s) with all data for entry = 1945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347585 (5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C18H21ClN4O/c1-12-8-15(19)5-6-16(12)13-4-3-7-23(11-13)18(24)14-9-17(20-2)22-21-10-14/h5-6,8-10,13H,3-4,7,11H2,1-2H3,(H,20,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347538 (4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C20H24ClN3O/c1-14-11-17(21)6-7-18(14)16-5-4-10-24(13-16)20(25)15-8-9-22-19(12-15)23(2)3/h6-9,11-12,16H,4-5,10,13H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347545 (4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C19H22ClN3O/c1-13-10-16(20)5-6-17(13)15-4-3-9-23(12-15)19(24)14-7-8-22-18(11-14)21-2/h5-8,10-11,15H,3-4,9,12H2,1-2H3,(H,21,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347577 (4-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(OC)cc1C Show InChI InChI=1S/C20H25N3O2/c1-14-11-17(25-3)6-7-18(14)16-5-4-10-23(13-16)20(24)15-8-9-22-19(12-15)21-2/h6-9,11-12,16H,4-5,10,13H2,1-3H3,(H,21,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347571 (4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C19H19ClF3N3O/c1-24-17-9-12(6-7-25-17)18(27)26-8-2-3-13(11-26)15-5-4-14(20)10-16(15)19(21,22)23/h4-7,9-10,13H,2-3,8,11H2,1H3,(H,24,25)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347578 (4-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(OC)cc1C(F)(F)F Show InChI InChI=1S/C20H22F3N3O2/c1-24-18-10-13(7-8-25-18)19(27)26-9-3-4-14(12-26)16-6-5-15(28-2)11-17(16)20(21,22)23/h5-8,10-11,14H,3-4,9,12H2,1-2H3,(H,24,25)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347579 (4-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...) Show SMILES CCOc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1ccnc(NC)c1 Show InChI InChI=1S/C20H24ClN3O2/c1-3-26-18-12-16(21)6-7-17(18)15-5-4-10-24(13-15)20(25)14-8-9-23-19(11-14)22-2/h6-9,11-12,15H,3-5,10,13H2,1-2H3,(H,22,23)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347585 (5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C18H21ClN4O/c1-12-8-15(19)5-6-16(12)13-4-3-7-23(11-13)18(24)14-9-17(20-2)22-21-10-14/h5-6,8-10,13H,3-4,7,11H2,1-2H3,(H,20,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347518 (3-Chloro-5-{[3-(4-chloro-2-methylphenyl)piperidin-...) Show SMILES CCc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C20H23ClN2O/c1-3-18-12-15(8-9-22-18)20(24)23-10-4-5-16(13-23)19-7-6-17(21)11-14(19)2/h6-9,11-12,16H,3-5,10,13H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347591 (5-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C18H18ClF3N4O/c1-23-16-7-12(9-24-25-16)17(27)26-6-2-3-11(10-26)14-5-4-13(19)8-15(14)18(20,21)22/h4-5,7-9,11H,2-3,6,10H2,1H3,(H,23,25)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347599 (5-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...) Show SMILES CCOc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(c1)N(C)C Show InChI InChI=1S/C20H25ClN4O2/c1-4-27-18-11-16(21)7-8-17(18)14-6-5-9-25(13-14)20(26)15-10-19(24(2)3)23-22-12-15/h7-8,10-12,14H,4-6,9,13H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347547 (2-(Azetidin-1-yl)-4-{[3-(4-chloro-2-methylphenyl)p...) Show SMILES Cc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1ccnc(c1)N1CCC1 Show InChI InChI=1S/C21H24ClN3O/c1-15-12-18(22)5-6-19(15)17-4-2-9-25(14-17)21(26)16-7-8-23-20(13-16)24-10-3-11-24/h5-8,12-13,17H,2-4,9-11,14H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347612 (3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1-methy...) Show SMILES Cn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C17H17ClF3N3O/c1-23-9-12(8-22-23)16(25)24-6-2-3-11(10-24)14-5-4-13(18)7-15(14)17(19,20)21/h4-5,7-9,11H,2-3,6,10H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347575 (4-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...) Show SMILES CCOc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1ccnc(c1)N(C)C Show InChI InChI=1S/C21H26ClN3O2/c1-4-27-19-13-17(22)7-8-18(19)16-6-5-11-25(14-16)21(26)15-9-10-23-20(12-15)24(2)3/h7-10,12-13,16H,4-6,11,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347576 (4-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...) Show SMILES COc1ccc(C2CCCN(C2)C(=O)c2ccnc(c2)N(C)C)c(c1)C(F)(F)F Show InChI InChI=1S/C21H24F3N3O2/c1-26(2)19-11-14(8-9-25-19)20(28)27-10-4-5-15(13-27)17-7-6-16(29-3)12-18(17)21(22,23)24/h6-9,11-12,15H,4-5,10,13H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347521 (3-Chloro-5-{[3-(4-methoxy-2-methylphenyl)piperidin...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C20H21ClF3N3O/c1-26(2)18-10-13(7-8-25-18)19(28)27-9-3-4-14(12-27)16-6-5-15(21)11-17(16)20(22,23)24/h5-8,10-11,14H,3-4,9,12H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347590 (5-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...) Show SMILES CN(C)c1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C19H20ClF3N4O/c1-26(2)17-8-13(10-24-25-17)18(28)27-7-3-4-12(11-27)15-6-5-14(20)9-16(15)19(21,22)23/h5-6,8-10,12H,3-4,7,11H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347607 (3-(4-Chloro-2-methylphenyl)-1-[(1-ethyl-1H-pyrazol...) Show SMILES CCn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C18H22ClN3O/c1-3-22-12-15(10-20-22)18(23)21-8-4-5-14(11-21)17-7-6-16(19)9-13(17)2/h6-7,9-10,12,14H,3-5,8,11H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347584 (5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES CN(C)c1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C19H23ClN4O/c1-13-9-16(20)6-7-17(13)14-5-4-8-24(12-14)19(25)15-10-18(23(2)3)22-21-11-15/h6-7,9-11,14H,4-5,8,12H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347594 (5-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(OC)cc1C Show InChI InChI=1S/C19H24N4O2/c1-13-9-16(25-3)6-7-17(13)14-5-4-8-23(12-14)19(24)15-10-18(20-2)22-21-11-15/h6-7,9-11,14H,4-5,8,12H2,1-3H3,(H,20,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347596 (5-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...) Show SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(OC)cc1C(F)(F)F Show InChI InChI=1S/C19H21F3N4O2/c1-23-17-8-13(10-24-25-17)18(27)26-7-3-4-12(11-26)15-6-5-14(28-2)9-16(15)19(20,21)22/h5-6,8-10,12H,3-4,7,11H2,1-2H3,(H,23,25)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347541 (4-{[3-(4-Chlorophenyl)piperidin-1-yl]carbonyl}-N-m...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H20ClN3O/c1-20-17-11-14(8-9-21-17)18(23)22-10-2-3-15(12-22)13-4-6-16(19)7-5-13/h4-9,11,15H,2-3,10,12H2,1H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347610 (4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES Cc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnn(C)c1N Show InChI InChI=1S/C17H21ClN4O/c1-11-8-13(18)5-6-14(11)12-4-3-7-22(10-12)17(23)15-9-20-21(2)16(15)19/h5-6,8-9,12H,3-4,7,10,19H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347595 (5-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...) Show SMILES COc1ccc(C2CCCN(C2)C(=O)c2cnnc(c2)N(C)C)c(C)c1 Show InChI InChI=1S/C20H26N4O2/c1-14-10-17(26-4)7-8-18(14)15-6-5-9-24(13-15)20(25)16-11-19(23(2)3)22-21-12-16/h7-8,10-12,15H,5-6,9,13H2,1-4H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347609 (3-(4-Chloro-2-methylphenyl)-1-[(1-methyl-1H-pyrazo...) Show SMILES Cc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnn(C)c1 Show InChI InChI=1S/C17H20ClN3O/c1-12-8-15(18)5-6-16(12)13-4-3-7-21(11-13)17(22)14-9-19-20(2)10-14/h5-6,8-10,13H,3-4,7,11H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347598 (5-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...) Show SMILES CCOc1cc(Cl)ccc1C1CCCN(C1)C(=O)c1cnnc(NC)c1 Show InChI InChI=1S/C19H23ClN4O2/c1-3-26-17-10-15(20)6-7-16(17)13-5-4-8-24(12-13)19(25)14-9-18(21-2)23-22-11-14/h6-7,9-11,13H,3-5,8,12H2,1-2H3,(H,21,23)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347613 (3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1-ethyl...) Show SMILES CCn1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C18H19ClF3N3O/c1-2-25-11-13(9-23-25)17(26)24-7-3-4-12(10-24)15-6-5-14(19)8-16(15)18(20,21)22/h5-6,8-9,11-12H,2-4,7,10H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347608 (3-(4-Chloro-2-methylphenyl)-1-{[1-(propan-2-yl)-1H...) Show SMILES CC(C)n1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C19H24ClN3O/c1-13(2)23-12-16(10-21-23)19(24)22-8-4-5-15(11-22)18-7-6-17(20)9-14(18)3/h6-7,9-10,12-13,15H,4-5,8,11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347532 (4-{[(3R)-3-(4-Chlorophenyl)piperidin-1-yl]carbonyl...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCC[C@@H](C1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H22ClN3O/c1-22(2)18-12-15(9-10-21-18)19(24)23-11-3-4-16(13-23)14-5-7-17(20)8-6-14/h5-10,12,16H,3-4,11,13H2,1-2H3/t16-/m0/s1	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347516 (4-{[3-(2,4-Dichlorophenyl)piperidin-1-yl]carbonyl}...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H21Cl2N3O/c1-23(2)18-10-13(7-8-22-18)19(25)24-9-3-4-14(12-24)16-6-5-15(20)11-17(16)21/h5-8,10-11,14H,3-4,9,12H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347528 (N,N-Dimethyl-4-{[3-(2-methylphenyl)piperidin-1-yl]...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccccc1C Show InChI InChI=1S/C20H25N3O/c1-15-7-4-5-9-18(15)17-8-6-12-23(14-17)20(24)16-10-11-21-19(13-16)22(2)3/h4-5,7,9-11,13,17H,6,8,12,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347602 (3-(4-Chloro-2-methylphenyl)-1-[(1,3-dimethyl-1H-py...) Show SMILES Cc1nn(C)cc1C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C18H22ClN3O/c1-12-9-15(19)6-7-16(12)14-5-4-8-22(10-14)18(23)17-11-21(3)20-13(17)2/h6-7,9,11,14H,4-5,8,10H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347597 (5-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...) Show SMILES COc1ccc(C2CCCN(C2)C(=O)c2cnnc(c2)N(C)C)c(c1)C(F)(F)F Show InChI InChI=1S/C20H23F3N4O2/c1-26(2)18-9-14(11-24-25-18)19(28)27-8-4-5-13(12-27)16-7-6-15(29-3)10-17(16)20(21,22)23/h6-7,9-11,13H,4-5,8,12H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347559 (N,N-Dimethyl-4-({3-[2-(trifluoromethyl)phenyl]pipe...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H22F3N3O/c1-25(2)18-12-14(9-10-24-18)19(27)26-11-5-6-15(13-26)16-7-3-4-8-17(16)20(21,22)23/h3-4,7-10,12,15H,5-6,11,13H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347568 (N-Methyl-4-({3-[2-(trifluoromethyl)phenyl]piperidi...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H20F3N3O/c1-23-17-11-13(8-9-24-17)18(26)25-10-4-5-14(12-25)15-6-2-3-7-16(15)19(20,21)22/h2-3,6-9,11,14H,4-5,10,12H2,1H3,(H,23,24)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347530 (4-{[3-(4-Chlorophenyl)piperidin-1-yl]carbonyl}-N,N...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H22ClN3O/c1-22(2)18-12-15(9-10-21-18)19(24)23-11-3-4-16(13-23)14-5-7-17(20)8-6-14/h5-10,12,16H,3-4,11,13H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347620 (4-{[5-(4-Chloro-2-methylphenyl)-1,2,3,4-tetrahydro...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(=C1)c1ccc(Cl)cc1C |c:16| Show InChI InChI=1S/C20H22ClN3O/c1-14-11-17(21)6-7-18(14)16-5-4-10-24(13-16)20(25)15-8-9-22-19(12-15)23(2)3/h6-9,11-13H,4-5,10H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347520 (4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...) Show SMILES CCc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C20H20ClF3N2O/c1-2-16-10-13(7-8-25-16)19(27)26-9-3-4-14(12-26)17-6-5-15(21)11-18(17)20(22,23)24/h5-8,10-11,14H,2-4,9,12H2,1H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347525 (3-Chloro-5-{[3-(2-methoxyphenyl)piperidin-1-yl]car...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(C)cc1 Show InChI InChI=1S/C20H25N3O/c1-15-6-8-16(9-7-15)18-5-4-12-23(14-18)20(24)17-10-11-21-19(13-17)22(2)3/h6-11,13,18H,4-5,12,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347525 (3-Chloro-5-{[3-(2-methoxyphenyl)piperidin-1-yl]car...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(C)cc1 Show InChI InChI=1S/C20H25N3O/c1-15-6-8-16(9-7-15)18-5-4-12-23(14-18)20(24)17-10-11-21-19(13-17)22(2)3/h6-11,13,18H,4-5,12,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347615 (4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...) Show SMILES Cn1cc(C(=O)N2CCCC(C2)c2ccc(Cl)cc2C(F)(F)F)c(N)n1 Show InChI InChI=1S/C17H18ClF3N4O/c1-24-9-13(15(22)23-24)16(26)25-6-2-3-10(8-25)12-5-4-11(18)7-14(12)17(19,20)21/h4-5,7,9-10H,2-3,6,8H2,1H3,(H2,22,23)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347614 (3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-{[1-(prop...) Show SMILES CC(C)n1cc(cn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C(F)(F)F Show InChI InChI=1S/C19H21ClF3N3O/c1-12(2)26-11-14(9-24-26)18(27)25-7-3-4-13(10-25)16-6-5-15(20)8-17(16)19(21,22)23/h5-6,8-9,11-13H,3-4,7,10H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347589 (5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES COc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C18H20ClN3O2/c1-12-8-15(19)5-6-16(12)13-4-3-7-22(11-13)18(23)14-9-17(24-2)21-20-10-14/h5-6,8-10,13H,3-4,7,11H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347569 (4-{[3-(4-Methoxyphenyl)piperidin-1-yl]carbonyl}-N-...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(OC)cc1 Show InChI InChI=1S/C19H23N3O2/c1-20-18-12-15(9-10-21-18)19(23)22-11-3-4-16(13-22)14-5-7-17(24-2)8-6-14/h5-10,12,16H,3-4,11,13H2,1-2H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347562 (4-{[3-(2-Methoxyphenyl)piperidin-1-yl]carbonyl}-N,...) Show SMILES COc1ccccc1C1CCCN(C1)C(=O)c1ccnc(c1)N(C)C Show InChI InChI=1S/C20H25N3O2/c1-22(2)19-13-15(10-11-21-19)20(24)23-12-6-7-16(14-23)17-8-4-5-9-18(17)25-3/h4-5,8-11,13,16H,6-7,12,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347619 (4-{[5-(4-Chlorophenyl)-1,2,3,4-tetrahydropyridin-1...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(=C1)c1ccc(Cl)cc1 |c:16| Show InChI InChI=1S/C19H20ClN3O/c1-22(2)18-12-15(9-10-21-18)19(24)23-11-3-4-16(13-23)14-5-7-17(20)8-6-14/h5-10,12-13H,3-4,11H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347525 (3-Chloro-5-{[3-(2-methoxyphenyl)piperidin-1-yl]car...) Show SMILES CN(C)c1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(C)cc1 Show InChI InChI=1S/C20H25N3O/c1-15-6-8-16(9-7-15)18-5-4-12-23(14-18)20(24)17-10-11-21-19(13-17)22(2)3/h6-11,13,18H,4-5,12,14H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347626 (4-{[3-(4-Chlorophenyl)azepan-1-yl]carbonyl}-N-meth...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCCC(C1)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H22ClN3O/c1-21-18-12-15(9-10-22-18)19(24)23-11-3-2-4-16(13-23)14-5-7-17(20)8-6-14/h5-10,12,16H,2-4,11,13H2,1H3,(H,21,22)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347570 (4-{[3-(2-Methoxyphenyl)piperidin-1-yl]carbonyl}-N-...) Show SMILES CNc1cc(ccn1)C(=O)N1CCCC(C1)c1ccccc1OC Show InChI InChI=1S/C19H23N3O2/c1-20-18-12-14(9-10-21-18)19(23)22-11-5-6-15(13-22)16-7-3-4-8-17(16)24-2/h3-4,7-10,12,15H,5-6,11,13H2,1-2H3,(H,20,21)	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM347519 (4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...) Show SMILES Cc1cc(ccn1)C(=O)N1CCCC(C1)c1ccc(Cl)cc1C Show InChI InChI=1S/C19H21ClN2O/c1-13-10-17(20)5-6-18(13)16-4-3-9-22(12-16)19(23)15-7-8-21-14(2)11-15/h5-8,10-11,16H,3-4,9,12H2,1-2H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9790201 (2017) BindingDB Entry DOI: 10.7270/Q2377BVZ
					More data for this Ligand-Target Pair

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