Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16384 (4-(4-fluorophenyl)-5-[3-(2-methoxyphenyl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16385 (5-[3-(2-ethoxyphenyl)-[1,2,4]triazolo[3,4-a]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16390 (4-(2,4-difluorophenyl)-5-[3-(1-methylcyclopropyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16393 (5-{3-tert-butyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16392 (4-(2,4-difluorophenyl)-5-[3-(1-methylcyclobutyl)-[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16398 (4-(2,5-difluorophenyl)-5-[3-(1-methylcyclobutyl)-[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16404 (5-{3-tert-butyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16346 (4-(4-chloro-2-fluorophenyl)-5-[3-(propan-2-yl)-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16401 (5-[3-(1-methylcyclopropyl)-[1,2,4]triazolo[3,4-a]p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16348 (4-(2-chloro-4-fluorophenyl)-5-[3-(propan-2-yl)-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16403 (5-[3-(1-methylcyclobutyl)-[1,2,4]triazolo[3,4-a]py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16405 (3-(2,5-difluorophenyl)-4-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16396 (4-(2,5-difluorophenyl)-5-[3-(1-methylcyclopropyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16340 (4-(2-chlorophenyl)-5-[3-(propan-2-yl)-[1,2,4]triaz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16351 (5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16386 (5-{3-tert-butyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16389 (5-{3-cyclopropyl-[1,2,4]triazolo[3,4-a]pyridin-6-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16391 (5-{3-cyclobutyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16350 (5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16337 (4-(2-fluoro-5-methylphenyl)-5-[3-(propan-2-yl)-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16341 (4-(2,4-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16379 (N-ethyl-6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-N-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM15414 (4-(4-fluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]triaz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16347 (4-(5-chloro-2-fluorophenyl)-5-[3-(propan-2-yl)-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16364 (N-ethyl-6-(4-phenyl-1,3-oxazol-5-yl)-[1,2,4]triazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16377 (6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-N-(propan-2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16359 (4-(2-chloro-4,5-difluorophenyl)-5-[3-(propan-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16342 (4-(2,5-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16407 (4-(2,5-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16336 (4-(4-fluoro-3-methylphenyl)-5-[3-(propan-2-yl)-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16352 (5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16372 (N-ethyl-6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16400 (5-{3-cyclopropyl-[1,2,4]triazolo[3,4-a]pyridin-6-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16360 (4-(3-bromo-4-fluorophenyl)-5-[3-(propan-2-yl)-[1,2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16356 (4-(2,4-dichlorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16399 (5-{3-tert-butyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16376 (4-(4-fluorophenyl)-5-[3-(2-methylpropyl)-[1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16402 (5-{3-cyclobutyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16365 (N-ethyl-N-methyl-6-(4-phenyl-1,3-oxazol-5-yl)-[1,2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16333 (4-phenyl-5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16397 (5-{3-cyclobutyl-[1,2,4]triazolo[3,4-a]pyridin-6-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16375 (5-{3-cyclopropyl-[1,2,4]triazolo[3,4-a]pyridin-6-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16354 (5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16387 (4-{6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16383 (4-(4-fluorophenyl)-5-{3-phenyl-[1,2,4]triazolo[3,4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16345 (4-(3-chloro-4-fluorophenyl)-5-[3-(propan-2-yl)-[1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12.4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16339 (4-(3-chlorophenyl)-5-[3-(propan-2-yl)-[1,2,4]triaz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13.5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16381 (4-(4-fluorophenyl)-5-[3-(1-methylcyclobutyl)-[1,2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16357 (4-(2,3-dichlorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM16343 (4-(2,6-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14.6 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Pfizer | Assay Description The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al... | Bioorg Med Chem Lett 16: 4339-44 (2006) Article DOI: 10.1016/j.bmcl.2006.05.056 BindingDB Entry DOI: 10.7270/Q2251GFZ | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 76 total ) | Next | Last >> |