Compile Data Set for Download or QSAR

Found 152 hits of ic50 for UniProtKB: P68403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) Show SMILES COc1ccc2n(C)c3c(c4C(=O)NC(=O)c4c4c5ccccc5n(CCC#N)c34)c2c1 Show InChI InChI=1S/C25H18N4O3/c1-28-16-9-8-13(32-2)12-15(16)19-21-20(24(30)27-25(21)31)18-14-6-3-4-7-17(14)29(11-5-10-26)23(18)22(19)28/h3-4,6-9,12H,5,11H2,1-2H3,(H,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3049 (23-[3-(dimethylamino)-2-hydroxypropyl]-7-methoxy-3...) Show SMILES COc1ccc2n(C)c3c(c4C(=O)NC(=O)c4c4c5ccccc5n(CC(O)CN(C)C)c34)c2c1 Show InChI InChI=1S/C27H26N4O4/c1-29(2)12-14(32)13-31-19-8-6-5-7-16(19)20-22-23(27(34)28-26(22)33)21-17-11-15(35-4)9-10-18(17)30(3)24(21)25(20)31/h5-11,14,32H,12-13H2,1-4H3,(H,28,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2714 (3-[(2S)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3C[C@@H](CN)CCn3c3ccccc23)c2ccccc12 |r,t:4| Show InChI InChI=1S/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3047 (4-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) Show SMILES COc1ccc2n(C)c3c(c4C(=O)NC(=O)c4c4c5ccccc5n(CCCC#N)c34)c2c1 Show InChI InChI=1S/C26H20N4O3/c1-29-17-10-9-14(33-2)13-16(17)20-22-21(25(31)28-26(22)32)19-15-7-3-4-8-18(15)30(12-6-5-11-27)24(19)23(20)29/h3-4,7-10,13H,5-6,12H2,1-2H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM50282632 (3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...) Show SMILES CN1C[C@@H]2Cc3c(C4=C(C(=O)NC4=O)c4cn(C)c5ccccc45)c4ccccc4n3C[C@H]2C1 |r,t:7| Show InChI InChI=1S/C28H26N4O2/c1-30-12-16-11-23-24(19-8-4-6-10-22(19)32(23)14-17(16)13-30)26-25(27(33)29-28(26)34)20-15-31(2)21-9-5-3-7-18(20)21/h3-10,15-17H,11-14H2,1-2H3,(H,29,33,34)/t16-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 1				Bioorg Med Chem Lett 4: 1303-1308 (1994) Article DOI: 10.1016/S0960-894X(01)80349-8 BindingDB Entry DOI: 10.7270/Q27H1JJ4
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3046 (3-{7,19-dimethoxy-23-methyl-12,14-dioxo-3,13,23-tr...) Show SMILES COc1ccc2n(C)c3c(c4C(=O)NC(=O)c4c4c5cc(OC)ccc5n(CCC#N)c34)c2c1 Show InChI InChI=1S/C26H20N4O4/c1-29-17-7-5-13(33-2)11-15(17)19-21-22(26(32)28-25(21)31)20-16-12-14(34-3)6-8-18(16)30(10-4-9-27)24(20)23(19)29/h5-8,11-12H,4,10H2,1-3H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM50282632 (3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10a-hexahydro-1...) Show SMILES CN1C[C@@H]2Cc3c(C4=C(C(=O)NC4=O)c4cn(C)c5ccccc45)c4ccccc4n3C[C@H]2C1 |r,t:7| Show InChI InChI=1S/C28H26N4O2/c1-30-12-16-11-23-24(19-8-4-6-10-22(19)32(23)14-17(16)13-30)26-25(27(33)29-28(26)34)20-15-31(2)21-9-5-3-7-18(20)21/h3-10,15-17H,11-14H2,1-2H3,(H,29,33,34)/t16-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta				Bioorg Med Chem Lett 4: 1303-1308 (1994) Article DOI: 10.1016/S0960-894X(01)80349-8 BindingDB Entry DOI: 10.7270/Q27H1JJ4
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2700 (3-[2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CC(CN)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3035 (3-{7,19-dihydroxy-23-methyl-14-oxo-3,13,23-triazah...) Show SMILES Cn1c2ccc(O)cc2c2c3C(=O)NCc3c3c4cc(O)ccc4n(CCC#N)c3c12 Show InChI InChI=1S/C24H18N4O3/c1-27-17-5-3-12(29)9-14(17)20-21-16(11-26-24(21)31)19-15-10-13(30)4-6-18(15)28(8-2-7-25)23(19)22(20)27/h3-6,9-10,29-30H,2,8,11H2,1H3,(H,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2712 (3-(1-methyl-1H-indol-3-yl)-4-{2-[(methylamino)meth...) Show SMILES CNCC1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(C)c3ccccc13)c1ccccc21 |t:11| Show InChI InChI=1S/C27H26N4O2/c1-28-14-16-11-12-31-21-10-6-4-8-18(21)23(22(31)13-16)25-24(26(32)29-27(25)33)19-15-30(2)20-9-5-3-7-17(19)20/h3-10,15-16,28H,11-14H2,1-2H3,(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2715 (3-[(2R)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3C[C@H](CN)CCn3c3ccccc23)c2ccccc12 |r,t:4| Show InChI InChI=1S/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3175 (3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H23N5O2S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2699 (3-[2-(aminomethyl)-1H,2H,3H-benzo[b]pyrrolizin-9-y...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CC(CN)Cn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H22N4O2/c1-28-13-17(15-6-2-4-8-18(15)28)22-23(25(31)27-24(22)30)21-16-7-3-5-9-19(16)29-12-14(11-26)10-20(21)29/h2-9,13-14H,10-12,26H2,1H3,(H,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2702 (3-[3-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(CN)Cn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-13-15(12-27)10-11-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3044 (3-{7-methoxy-23-methyl-12,14-dioxo-3,13,23-triazah...) Show SMILES COc1ccc2n(CCC#N)c3c(c4C(=O)NC(=O)c4c4c5ccccc5n(C)c34)c2c1 Show InChI InChI=1S/C25H18N4O3/c1-28-16-7-4-3-6-14(16)18-20-21(25(31)27-24(20)30)19-15-12-13(32-2)8-9-17(15)29(11-5-10-26)23(19)22(18)28/h3-4,6-9,12H,5,11H2,1-2H3,(H,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3038 (23-[3-(dimethylamino)propyl]-7,19-dihydroxy-3,13,2...) Show SMILES CN(C)CCCn1c2ccc(O)cc2c2c3CNC(=O)c3c3c4cc(O)ccc4[nH]c3c12 Show InChI InChI=1S/C25H24N4O3/c1-28(2)8-3-9-29-19-7-5-14(31)11-16(19)20-17-12-26-25(32)22(17)21-15-10-13(30)4-6-18(15)27-23(21)24(20)29/h4-7,10-11,27,30-31H,3,8-9,12H2,1-2H3,(H,26,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2704 (3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(CN)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H26N4O2/c1-30-15-19(17-6-2-4-8-20(17)30)24-25(27(33)29-26(24)32)23-18-7-3-5-9-21(18)31-13-12-16(14-28)10-11-22(23)31/h2-9,15-16H,10-14,28H2,1H3,(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.5	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3179 (3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...) Show SMILES [#6]-n1cc(-[#6]-2=[#6](-[#6](=O)-[#7]-[#6]-2=O)-c2cn(-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H24N6O2/c1-30-13-17(15-7-2-4-9-19(15)30)21-22(24(33)29-23(21)32)18-14-31(12-6-11-28-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1H3,(H4,26,27,28)(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3033 (3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0...) Show SMILES Cn1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4n(CCC#N)c3c12 Show InChI InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3048 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3C(=O)NC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H24N4O3/c1-28(2)12-14(31)13-30-18-11-7-5-9-16(18)20-22-21(25(32)27-26(22)33)19-15-8-4-6-10-17(15)29(3)23(19)24(20)30/h4-11,14,31H,12-13H2,1-3H3,(H,27,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2703 (3-[3-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(CCN)Cn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H26N4O2/c1-30-15-19(17-6-2-4-8-20(17)30)24-25(27(33)29-26(24)32)23-18-7-3-5-9-21(18)31-14-16(12-13-28)10-11-22(23)31/h2-9,15-16H,10-14,28H2,1H3,(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3178 (3-(1-Methyl-3-indolyl)-4-[1-[3-(2-nitroguanidino)p...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCN=C(N)N[N+]([O-])=O)c3ccccc23)c2ccccc12 |w:17.17,t:4| Show InChI InChI=1S/C25H23N7O4/c1-30-13-17(15-7-2-4-9-19(15)30)21-22(24(34)28-23(21)33)18-14-31(20-10-5-3-8-16(18)20)12-6-11-27-25(26)29-32(35)36/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27,29)(H,28,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM50282633 ((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...) Show SMILES CN(C)C[C@H]1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(C)c3ccccc13)c1ccccc21 |t:12| Show InChI InChI=1S/C28H28N4O2/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 1				Bioorg Med Chem Lett 4: 1303-1308 (1994) Article DOI: 10.1016/S0960-894X(01)80349-8 BindingDB Entry DOI: 10.7270/Q27H1JJ4
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3176 (Bisindolylmaleimide 11c | [(4-{3-[4-(1-methyl-1H-i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H25N5O2S/c1-30-14-18(16-8-2-4-10-20(16)30)22-23(25(33)29-24(22)32)19-15-31(12-6-7-13-34-26(27)28)21-11-5-3-9-17(19)21/h2-5,8-11,14-15H,6-7,12-13H2,1H3,(H3,27,28)(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM50282633 ((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...) Show SMILES CN(C)C[C@H]1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(C)c3ccccc13)c1ccccc21 |t:12| Show InChI InChI=1S/C28H28N4O2/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	30.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta				Bioorg Med Chem Lett 4: 1303-1308 (1994) Article DOI: 10.1016/S0960-894X(01)80349-8 BindingDB Entry DOI: 10.7270/Q27H1JJ4
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3180 (3-[1-(4-Amidinobutyl)-3-indolyl]-4-(1-methyl-3-ind...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCCC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H25N5O2/c1-30-14-18(16-8-2-4-10-20(16)30)23-24(26(33)29-25(23)32)19-15-31(13-7-6-12-22(27)28)21-11-5-3-9-17(19)21/h2-5,8-11,14-15H,6-7,12-13H2,1H3,(H3,27,28)(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3040 (23-(3-aminopropyl)-3-methyl-3,13,23-triazahexacycl...) Show SMILES Cn1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4n(CCCN)c3c12 Show InChI InChI=1S/C24H22N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,11-13,25H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3171 (3-(1-methyl-1H-indol-3-yl)-4-{1-[3-(methylamino)pr...) Show SMILES CNCCCn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C25H24N4O2/c1-26-12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-28(2)20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3043 (3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...) Show SMILES Cn1c2ccccc2c2c3C(=O)NC(=O)c3c3c4ccccc4n(CCC#N)c3c12 Show InChI InChI=1S/C24H16N4O2/c1-27-15-9-4-2-7-13(15)17-19-20(24(30)26-23(19)29)18-14-8-3-5-10-16(14)28(12-6-11-25)22(18)21(17)27/h2-5,7-10H,6,12H2,1H3,(H,26,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3174 (Bisindolylmaleimide 11a | ROCHE screening, 56 | [(...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C24H21N5O2S/c1-28-12-16(14-6-2-4-8-18(14)28)20-21(23(31)27-22(20)30)17-13-29(10-11-32-24(25)26)19-9-5-3-7-15(17)19/h2-9,12-13H,10-11H2,1H3,(H3,25,26)(H,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2705 (3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyr...) Show SMILES CN(C)CC1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(C)c3ccccc13)c1ccccc21 |t:12| Show InChI InChI=1S/C28H28N4O2/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3039 (23-[3-(dimethylamino)propyl]-3-methyl-3,13,23-tria...) Show SMILES CN(C)CCCn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O/c1-28(2)13-8-14-30-20-12-7-5-10-17(20)21-18-15-27-26(31)23(18)22-16-9-4-6-11-19(16)29(3)24(22)25(21)30/h4-7,9-12H,8,13-15H2,1-3H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2681 (3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...) Show SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3ccccc23)c2ccccc12 |t:9| Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-8-14-30-16-20(18-10-5-7-12-22(18)30)24-23(25(31)27-26(24)32)19-15-29(3)21-11-6-4-9-17(19)21/h4-7,9-12,15-16H,8,13-14H2,1-3H3,(H,27,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2701 (3-[2-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CC(CCN)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H26N4O2/c1-30-15-19(17-6-2-4-8-20(17)30)24-25(27(33)29-26(24)32)23-18-7-3-5-9-21(18)31-13-11-16(10-12-28)14-22(23)31/h2-9,15-16H,10-14,28H2,1H3,(H,29,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3177 (Bisindolylmaleimide 11d | ROCHE screening, 58 | [(...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCCCSC(N)=N)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H27N5O2S/c1-31-15-19(17-9-3-5-11-21(17)31)23-24(26(34)30-25(23)33)20-16-32(22-12-6-4-10-18(20)22)13-7-2-8-14-35-27(28)29/h3-6,9-12,15-16H,2,7-8,13-14H2,1H3,(H3,28,29)(H,30,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2713 (3-[6,7,8,9-Tetrahydro-8-[(trimethylamino)methyl]py...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CC(C[N+](C)(C)C)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C29H30N4O2/c1-31-16-21(19-9-5-7-11-22(19)31)26-27(29(35)30-28(26)34)25-20-10-6-8-12-23(20)32-14-13-18(15-24(25)32)17-33(2,3)4/h5-12,16,18H,13-15,17H2,1-4H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3169 (3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCCN)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C25H24N4O2/c1-28-14-18(16-8-2-4-10-20(16)28)22-23(25(31)27-24(22)30)19-15-29(13-7-6-12-26)21-11-5-3-9-17(19)21/h2-5,8-11,14-15H,6-7,12-13,26H2,1H3,(H,27,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3034 (3-{7,19-dimethoxy-23-methyl-14-oxo-3,13,23-triazah...) Show SMILES COc1ccc2n(C)c3c(c4C(=O)NCc4c4c5cc(OC)ccc5n(CCC#N)c34)c2c1 Show InChI InChI=1S/C26H22N4O3/c1-29-19-7-5-14(32-2)11-16(19)22-23-18(13-28-26(23)31)21-17-12-15(33-3)6-8-20(17)30(10-4-9-27)25(21)24(22)29/h5-8,11-12H,4,10,13H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3167 (3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCN)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C23H20N4O2/c1-26-12-16(14-6-2-4-8-18(14)26)20-21(23(29)25-22(20)28)17-13-27(11-10-24)19-9-5-3-7-15(17)19/h2-9,12-13H,10-11,24H2,1H3,(H,25,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2695 (3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCN)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C24H22N4O2/c1-27-13-17(15-7-2-4-9-19(15)27)21-22(24(30)26-23(21)29)18-14-28(12-6-11-25)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12,25H2,1H3,(H,26,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2695 (3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCN)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C24H22N4O2/c1-27-13-17(15-7-2-4-9-19(15)27)21-22(24(30)26-23(21)29)18-14-28(12-6-11-25)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12,25H2,1H3,(H,26,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3170 (3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCCCN)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H26N4O2/c1-29-15-19(17-9-3-5-11-21(17)29)23-24(26(32)28-25(23)31)20-16-30(14-8-2-7-13-27)22-12-6-4-10-18(20)22/h3-6,9-12,15-16H,2,7-8,13-14,27H2,1H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	7.5	30
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3042 (23-[3-(dimethylamino)-2-hydroxypropyl]-7-methoxy-3...) Show SMILES COc1ccc2n(C)c3c(c4C(=O)NCc4c4c5ccccc5n(CC(O)CN(C)C)c34)c2c1 Show InChI InChI=1S/C27H28N4O3/c1-29(2)13-15(32)14-31-21-8-6-5-7-17(21)22-19-12-28-27(33)24(19)23-18-11-16(34-4)9-10-20(18)30(3)25(23)26(22)31/h5-11,15,32H,12-14H2,1-4H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM3173 (Bisindolylmaleimide 9 | Trimethyl[3-[3-[3-(1-methy...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCC[N+](C)(C)C)c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C27H28N4O2/c1-29-16-20(18-10-5-7-12-22(18)29)24-25(27(33)28-26(24)32)21-17-30(14-9-15-31(2,3)4)23-13-8-6-11-19(21)23/h5-8,10-13,16-17H,9,14-15H2,1-4H3/p+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 994-1001 (1992) Article DOI: 10.1021/jm00084a004 BindingDB Entry DOI: 10.7270/Q2M043KK
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM36604 (5'-Deoxybalanol, 7) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCCNC[C@H]1NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C28H26N2O9/c31-19-9-4-8-17(27(36)37)23(19)25(34)24-20(32)12-16(13-21(24)33)28(38)39-22-10-5-11-29-14-18(22)30-26(35)15-6-2-1-3-7-15/h1-4,6-9,12-13,18,22,29,31-33H,5,10-11,14H2,(H,30,35)(H,36,37)/t18-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	69	-9.93	95	n/a	n/a	n/a	n/a	7.5	30
University of California, San Diego					Assay Description Protein kinase C (PKC) enzyme inhibition assay using purified rat brain protein kinase C from Calbiochem #539494.				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2710 (3-[8-Amino-7,8,9,10-tetrahydro-6H-azepino[1,2-a]in...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCC(N)CCn3c3ccccc23)c2ccccc12 |t:4| Show InChI InChI=1S/C26H24N4O2/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-13-12-15(27)10-11-21(22)30/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 36: 21-9 (1993) Article DOI: 10.1021/jm00053a003 BindingDB Entry DOI: 10.7270/Q29P2ZTD
					More data for this Ligand-Target Pair

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