Found 55 hits of ic50 for UniProtKB: P40136 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50479983
(Adefovir Diphosphate)Show SMILES Nc1ncnc2n(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)cnc12 Show InChI InChI=1S/C8H14N5O10P3/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-21-5-24(14,15)22-26(19,20)23-25(16,17)18/h3-4H,1-2,5H2,(H,14,15)(H,19,20)(H2,9,10,11)(H2,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
MCE
KEGG
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50571754
(CHEMBL4853492)Show SMILES Nc1nc(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)c(s1)-c1cccc(OCc2ccccc2)c1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50571756
(CHEMBL4855382)Show SMILES CC(C)Oc1ccc(cc1)-c1sc(N)nc1CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 428 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50571753
(CHEMBL4848421)Show SMILES CNC(=O)c1ccc(cc1)-c1sc(N)nc1CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 704 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486025
(CHEMBL2203672)Show SMILES Nc1cc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)cc(c1)C(O)=O Show InChI InChI=1S/C21H14N2O4/c22-12-8-11(21(26)27)9-13(10-12)23-20(25)17-7-3-6-15-14-4-1-2-5-16(14)19(24)18(15)17/h1-10H,22H2,(H,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50571757
(CHEMBL4858677)Show SMILES Nc1nc(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)c(s1)-c1cccc(F)c1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486023
(CHEMBL2203681)Show SMILES CN(C)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C22H18N2O2/c1-24(2)15-8-5-7-14(13-15)23-22(26)19-12-6-11-17-16-9-3-4-10-18(16)21(25)20(17)19/h3-13H,1-2H3,(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262712
(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)Show SMILES OC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C21H13NO4/c23-19-16-8-2-1-7-14(16)15-9-4-10-17(18(15)19)20(24)22-13-6-3-5-12(11-13)21(25)26/h1-11H,(H,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262712
(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)Show SMILES OC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C21H13NO4/c23-19-16-8-2-1-7-14(16)15-9-4-10-17(18(15)19)20(24)22-13-6-3-5-12(11-13)21(25)26/h1-11H,(H,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrs |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262713
(4-(3-methoxy-phenyl)-3a,4,5,9b-tetrahydro-3H-cyclo...)Show SMILES COc1cccc(c1)[C@H]1Nc2ccc(cc2[C@@H]2C=CC[C@H]12)C(O)=O |r,c:19| Show InChI InChI=1S/C20H19NO3/c1-24-14-5-2-4-12(10-14)19-16-7-3-6-15(16)17-11-13(20(22)23)8-9-18(17)21-19/h2-6,8-11,15-16,19,21H,7H2,1H3,(H,22,23)/t15-,16+,19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262713
(4-(3-methoxy-phenyl)-3a,4,5,9b-tetrahydro-3H-cyclo...)Show SMILES COc1cccc(c1)[C@H]1Nc2ccc(cc2[C@@H]2C=CC[C@H]12)C(O)=O |r,c:19| Show InChI InChI=1S/C20H19NO3/c1-24-14-5-2-4-12(10-14)19-16-7-3-6-15(16)17-11-13(20(22)23)8-9-18(17)21-19/h2-6,8-11,15-16,19,21H,7H2,1H3,(H,22,23)/t15-,16+,19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrs |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262712
(3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...)Show SMILES OC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C21H13NO4/c23-19-16-8-2-1-7-14(16)15-9-4-10-17(18(15)19)20(24)22-13-6-3-5-12(11-13)21(25)26/h1-11H,(H,22,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486008
(CHEMBL2203684)Show SMILES NC(=N)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C21H15N3O2/c22-20(23)12-5-3-6-13(11-12)24-21(26)17-10-4-9-15-14-7-1-2-8-16(14)19(25)18(15)17/h1-11H,(H3,22,23)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486009
(CHEMBL2203682)Show SMILES Fc1ccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)cc1Cl Show InChI InChI=1S/C20H11ClFNO2/c21-16-10-11(8-9-17(16)22)23-20(25)15-7-3-6-13-12-4-1-2-5-14(12)19(24)18(13)15/h1-10H,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50571758
(CHEMBL4852011)Show SMILES CC(C)Cc1sc(N)nc1-c1ccc(o1)P(O)(=O)OP(O)(=O)OP(O)(O)=O | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486021
(CHEMBL2203670)Show SMILES OC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1O Show InChI InChI=1S/C21H13NO5/c23-18-15(21(26)27)9-4-10-16(18)22-20(25)14-8-3-7-12-11-5-1-2-6-13(11)19(24)17(12)14/h1-10,23H,(H,22,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486014
(CHEMBL2203673)Show SMILES COc1ccc(cc1NC(=O)c1cccc2-c3ccccc3C(=O)c12)C(O)=O Show InChI InChI=1S/C22H15NO5/c1-28-18-10-9-12(22(26)27)11-17(18)23-21(25)16-8-4-7-14-13-5-2-3-6-15(13)20(24)19(14)16/h2-11H,1H3,(H,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486016
(CHEMBL2203669)Show SMILES Nc1ccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)cc1C(O)=O Show InChI InChI=1S/C21H14N2O4/c22-17-9-8-11(10-16(17)21(26)27)23-20(25)15-7-3-6-13-12-4-1-2-5-14(12)19(24)18(13)15/h1-10H,22H2,(H,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486015
(CHEMBL2203671)Show SMILES OC(=O)c1cc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)ccc1O Show InChI InChI=1S/C21H13NO5/c23-17-9-8-11(10-16(17)21(26)27)22-20(25)15-7-3-6-13-12-4-1-2-5-14(12)19(24)18(13)15/h1-10,23H,(H,22,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486020
(CHEMBL2203680)Show SMILES FC(F)(F)Oc1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C21H12F3NO3/c22-21(23,24)28-13-6-3-5-12(11-13)25-20(27)17-10-4-9-15-14-7-1-2-8-16(14)19(26)18(15)17/h1-11H,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486011
(CHEMBL2203678)Show SMILES COC(=O)c1ccc(OC)c(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C23H17NO5/c1-28-19-11-10-13(23(27)29-2)12-18(19)24-22(26)17-9-5-8-15-14-6-3-4-7-16(14)21(25)20(15)17/h3-12H,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50571755
(CHEMBL4852594)Show SMILES Nc1nc(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)c(s1)-c1ccccc1OCc1ccccc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Bacillus anthracis edema factor by cell free assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113581
BindingDB Entry DOI: 10.7270/Q2RJ4P8B |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262711
(4-[(anthracen-9-ylmethylene)-amino]-2-hydroxy-benz...)Show InChI InChI=1S/C22H15NO3/c24-21-12-16(9-10-19(21)22(25)26)23-13-20-17-7-3-1-5-14(17)11-15-6-2-4-8-18(15)20/h1-13,24H,(H,25,26)/b23-13+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262711
(4-[(anthracen-9-ylmethylene)-amino]-2-hydroxy-benz...)Show InChI InChI=1S/C22H15NO3/c24-21-12-16(9-10-19(21)22(25)26)23-13-20-17-7-3-1-5-14(17)11-15-6-2-4-8-18(15)20/h1-13,24H,(H,25,26)/b23-13+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrs |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486012
(CHEMBL2203675)Show SMILES OC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1Cl Show InChI InChI=1S/C21H12ClNO4/c22-18-15(21(26)27)9-4-10-16(18)23-20(25)14-8-3-7-12-11-5-1-2-6-13(11)19(24)17(12)14/h1-10H,(H,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486026
(CHEMBL2203667)Show SMILES COC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C22H15NO4/c1-27-22(26)13-6-4-7-14(12-13)23-21(25)18-11-5-10-16-15-8-2-3-9-17(15)20(24)19(16)18/h2-12H,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486013
(CHEMBL2203674)Show SMILES Cc1c(NC(=O)c2cccc3-c4ccccc4C(=O)c23)cccc1C(O)=O Show InChI InChI=1S/C22H15NO4/c1-12-13(22(26)27)8-5-11-18(12)23-21(25)17-10-4-9-15-14-6-2-3-7-16(14)20(24)19(15)17/h2-11H,1H3,(H,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486027
(CHEMBL2203683)Show SMILES ONC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1 Show InChI InChI=1S/C21H14N2O4/c24-19-16-8-2-1-7-14(16)15-9-4-10-17(18(15)19)21(26)22-13-6-3-5-12(11-13)20(25)23-27/h1-11,27H,(H,22,26)(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486024
(CHEMBL2203677)Show SMILES COC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1C Show InChI InChI=1S/C23H17NO4/c1-13-14(23(27)28-2)9-6-12-19(13)24-22(26)18-11-5-10-16-15-7-3-4-8-17(15)21(25)20(16)18/h3-12H,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486017
(CHEMBL2203666)Show InChI InChI=1S/C21H17NO3/c1-25-21(24)18-11-6-12-19(14-18)22-20(23)17-10-5-9-16(13-17)15-7-3-2-4-8-15/h2-14H,1H3,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243831
(3-(6-methoxypyridin-3-yl)-2-methylcyclopent-2-enon...)Show InChI InChI=1S/C12H13NO2/c1-8-10(4-5-11(8)14)9-3-6-12(15-2)13-7-9/h3,6-7H,4-5H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486010
(CHEMBL2203679)Show InChI InChI=1S/C21H15NO2S/c1-25-14-7-4-6-13(12-14)22-21(24)18-11-5-10-16-15-8-2-3-9-17(15)20(23)19(16)18/h2-12H,1H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486018
(CHEMBL466239)Show InChI InChI=1S/C20H13NO2/c22-19-16-10-5-4-9-14(16)15-11-6-12-17(18(15)19)20(23)21-13-7-2-1-3-8-13/h1-12H,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243793
(3-(6-methoxypyridin-2-yl)-2-methylcyclopent-2-enon...)Show InChI InChI=1S/C12H13NO2/c1-8-9(6-7-11(8)14)10-4-3-5-12(13-10)15-2/h3-5H,6-7H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243832
(3-(3-methoxyphenyl)cyclohex-2-enone | CHEMBL507392)Show InChI InChI=1S/C13H14O2/c1-15-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h3,5,7-9H,2,4,6H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243836
(3-(2-methoxyphenyl)cyclohex-2-enone | CHEMBL486251)Show InChI InChI=1S/C13H14O2/c1-15-13-8-3-2-7-12(13)10-5-4-6-11(14)9-10/h2-3,7-9H,4-6H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243790
(3-(benzo[d][1,3]dioxol-5-yl)cyclohex-2-enone | CHE...)Show InChI InChI=1S/C13H12O3/c14-11-3-1-2-9(6-11)10-4-5-12-13(7-10)16-8-15-12/h4-7H,1-3,8H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243834
(3-(1H-indol-5-yl)cyclohex-2-enone | CHEMBL449336)Show InChI InChI=1S/C14H13NO/c16-13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-15-14/h4-9,15H,1-3H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486019
(CHEMBL2203668)Show SMILES Nc1ccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c(c1)C(O)=O Show InChI InChI=1S/C21H14N2O4/c22-11-8-9-17(16(10-11)21(26)27)23-20(25)15-7-3-6-13-12-4-1-2-5-14(12)19(24)18(13)15/h1-10H,22H2,(H,23,25)(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243787
(3-phenylcyclohex-2-enone | CHEMBL503170)Show InChI InChI=1S/C12H12O/c13-12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243835
(3-Dibenzofuran-4-yl-5,5-dimethyl-cyclohex-2-enone ...)Show SMILES CC1(C)CC(=O)C=C(C1)c1cccc2c1oc1ccccc21 |c:6| Show InChI InChI=1S/C20H18O2/c1-20(2)11-13(10-14(21)12-20)15-7-5-8-17-16-6-3-4-9-18(16)22-19(15)17/h3-10H,11-12H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243792
(3-(1H-indol-5-yl)-5,5-dimethylcyclohex-2-enone | C...)Show InChI InChI=1S/C16H17NO/c1-16(2)9-13(8-14(18)10-16)11-3-4-15-12(7-11)5-6-17-15/h3-8,17H,9-10H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486028
(3-Benzoylamino-Benzoic Acid | CHEMBL1513568)Show InChI InChI=1S/C14H11NO3/c16-13(10-5-2-1-3-6-10)15-12-8-4-7-11(9-12)14(17)18/h1-9H,(H,15,16)(H,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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MCE
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PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243791
(3-(3-hydroxyphenyl)cyclohex-2-enone | CHEMBL488651)Show InChI InChI=1S/C12H12O2/c13-11-5-1-3-9(7-11)10-4-2-6-12(14)8-10/h1,3,5,7-8,13H,2,4,6H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50486022
(CHEMBL2203676)Show SMILES COC(=O)c1cc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)ccc1O Show InChI InChI=1S/C22H15NO5/c1-28-22(27)17-11-12(9-10-18(17)24)23-21(26)16-8-4-7-14-13-5-2-3-6-15(13)20(25)19(14)16/h2-11,24H,1H3,(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA |
Bioorg Med Chem 20: 368-76 (2012)
Article DOI: 10.1016/j.bmc.2011.10.091
BindingDB Entry DOI: 10.7270/Q2PK0K15 |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243833
(3-(quinolin-6-yl)cyclohex-2-enone | CHEMBL442887)Show InChI InChI=1S/C15H13NO/c17-14-5-1-3-11(10-14)12-6-7-15-13(9-12)4-2-8-16-15/h2,4,6-10H,1,3,5H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243830
(3-(furan-3-yl)cyclohex-2-enone | CHEMBL486250)Show InChI InChI=1S/C10H10O2/c11-10-3-1-2-8(6-10)9-4-5-12-7-9/h4-7H,1-3H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50262663
((3aS,4S,9bR)-4-(4-(methoxycarbonyl)phenyl)-3a,4,5,...)Show SMILES COC(=O)c1ccc(cc1)[C@H]1Nc2ccc(cc2[C@@H]2C=CC[C@H]12)C(O)=O |r,c:21| Show InChI InChI=1S/C21H19NO4/c1-26-21(25)13-7-5-12(6-8-13)19-16-4-2-3-15(16)17-11-14(20(23)24)9-10-18(17)22-19/h2-3,5-11,15-16,19,22H,4H2,1H3,(H,23,24)/t15-,16+,19-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrs |
Bioorg Med Chem 16: 7225-33 (2008)
Article DOI: 10.1016/j.bmc.2008.06.036
BindingDB Entry DOI: 10.7270/Q2R2116M |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243829
(3-(thiophen-2-yl)cyclohex-2-enone | CHEMBL451060)Show InChI InChI=1S/C10H10OS/c11-9-4-1-3-8(7-9)10-5-2-6-12-10/h2,5-7H,1,3-4H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
Calmodulin-sensitive adenylate cyclase
(Bacillus anthracis) | BDBM50243828
(3-(thiophen-3-yl)cyclohex-2-enone | CHEMBL474875)Show InChI InChI=1S/C10H10OS/c11-10-3-1-2-8(6-10)9-4-5-12-7-9/h4-7H,1-3H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch
Curated by ChEMBL
| Assay Description
Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA |
Bioorg Med Chem Lett 18: 4215-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.059
BindingDB Entry DOI: 10.7270/Q29G5MMN |
More data for this
Ligand-Target Pair | |
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