Compile Data Set for Download or QSAR

Found 96 hits of ic50 for UniProtKB: P11169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152749 (CHEMBL3781913) Show SMILES COc1ccccc1N1CCCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-30-21-11-6-5-10-20(21)27-12-7-13-28(15-14-27)22-19-16-26-29(23(19)25-17-24-22)18-8-3-2-4-9-18/h2-6,8-11,16-17H,7,12-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155671 (CHEMBL3780239) Show SMILES COc1ccc(F)cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-8-7-16(23)13-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453246 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-4-28(2,3)34-25(35)17-37-22-7-5-6-19(12-22)26-32-24-16-36-15-23(24)27(33-26)31-21-10-8-18(9-11-21)20-13-29-30-14-20/h5-14H,4,15-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453265 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-28(2,3)34-25(35)17-37-22-6-4-5-19(13-22)26-32-24-11-12-36-16-23(24)27(33-26)31-21-9-7-18(8-10-21)20-14-29-30-15-20/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453264 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H32N6O3/c1-3-22(4-2)32-27(36)18-38-24-7-5-6-20(14-24)28-34-26-12-13-37-17-25(26)29(35-28)33-23-10-8-19(9-11-23)21-15-30-31-16-21/h5-11,14-16,22H,3-4,12-13,17-18H2,1-2H3,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155656 (CHEMBL3781331) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C(N)=O Show InChI InChI=1S/C23H23N7O2/c1-32-20-8-7-16(21(24)31)13-19(20)28-9-11-29(12-10-28)22-18-14-27-30(23(18)26-15-25-22)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3,(H2,24,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155673 (CHEMBL3780972) Show SMILES COc1cc(F)ccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-13-16(23)7-8-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152824 (CHEMBL3781548) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1F Show InChI InChI=1S/C22H21FN6O/c1-30-20-9-5-4-8-19(20)27-10-12-28(13-11-27)21-16-14-26-29(22(16)25-15-24-21)18-7-3-2-6-17(18)23/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155746 (CHEMBL3781151) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccc(F)cc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-5-3-2-4-19(20)27-10-12-28(13-11-27)21-18-14-26-29(22(18)25-15-24-21)17-8-6-16(23)7-9-17/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453228 (US10729691, Example 13) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C28H28N6O3/c35-26(31-21-5-1-2-6-21)17-37-23-7-3-4-19(12-23)27-33-25-16-36-15-24(25)28(34-27)32-22-10-8-18(9-11-22)20-13-29-30-14-20/h3-4,7-14,21H,1-2,5-6,15-17H2,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155670 (CHEMBL3780144) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-7-17(14-24)13-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538375 (CHEMBL4633651) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H31N7O2/c1-28(2,3)35-25(36)17-37-22-6-4-5-19(13-22)26-33-24-11-12-29-16-23(24)27(34-26)32-21-9-7-18(8-10-21)20-14-30-31-15-20/h4-10,13-15,29H,11-12,16-17H2,1-3H3,(H,30,31)(H,35,36)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155715 (CHEMBL3781149) Show SMILES Oc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H28Br2ClN5O/c27-19-12-18-6-5-17-13-20(29)14-21(28)23(17)25(24(18)32-15-19)34-10-2-1-4-22(34)26(35)31-7-3-9-33-11-8-30-16-33/h8,11-16,22,25H,1-7,9-10H2,(H,31,35)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155585 (CHEMBL3780372) Show SMILES COc1ccncc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H21N7O/c1-29-19-7-8-22-14-18(19)26-9-11-27(12-10-26)20-17-13-25-28(21(17)24-15-23-20)16-5-3-2-4-6-16/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152776 (CHEMBL3780785) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(cnc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6O/c1-29-19-10-6-5-9-18(19)26-11-13-27(14-12-26)21-20-22(24-15-23-21)28(16-25-20)17-7-3-2-4-8-17/h2-10,15-16H,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453227 (US10729691, Example 12) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCC1 Show InChI InChI=1S/C27H26N6O3/c34-25(30-20-4-2-5-20)16-36-22-6-1-3-18(11-22)26-32-24-15-35-14-23(24)27(33-26)31-21-9-7-17(8-10-21)19-12-28-29-13-19/h1,3,6-13,20H,2,4-5,14-16H2,(H,28,29)(H,30,34)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155680 (CHEMBL3780717) Show SMILES N#Cc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H19N7/c23-14-17-5-4-8-19(13-17)27-9-11-28(12-10-27)21-20-15-26-29(22(20)25-16-24-21)18-6-2-1-3-7-18/h1-8,13,15-16H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155583 (CHEMBL3781835) Show SMILES COc1cccnc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H21N7O/c1-29-18-8-5-9-22-21(18)27-12-10-26(11-13-27)19-17-14-25-28(20(17)24-15-23-19)16-6-3-2-4-7-16/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155751 (CHEMBL3780460) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C22H20F2N6O/c1-31-20-5-3-2-4-19(20)28-6-8-29(9-7-28)21-18-13-27-30(22(18)26-14-25-21)17-11-15(23)10-16(24)12-17/h2-5,10-14H,6-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155745 (CHEMBL3780043) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(C)c1 Show InChI InChI=1S/C23H24N6O/c1-17-6-5-7-18(14-17)29-23-19(15-26-29)22(24-16-25-23)28-12-10-27(11-13-28)20-8-3-4-9-21(20)30-2/h3-9,14-16H,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453217 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C26H26N6O3/c1-16(2)29-24(33)15-35-21-5-3-4-18(10-21)25-31-23-14-34-13-22(23)26(32-25)30-20-8-6-17(7-9-20)19-11-27-28-12-19/h3-12,16H,13-15H2,1-2H3,(H,27,28)(H,29,33)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152825 (CHEMBL3780235) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-20-9-5-3-7-18(20)27-11-13-28(14-12-27)22-17-15-26-29(23(17)25-16-24-22)19-8-4-6-10-21(19)31-2/h3-10,15-16H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152827 (CHEMBL3781741) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(F)c1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-8-3-2-7-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-6-4-5-16(23)13-17/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155752 (CHEMBL3780527) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C1CCCC1 Show InChI InChI=1S/C21H26N6O/c1-28-19-9-5-4-8-18(19)25-10-12-26(13-11-25)20-17-14-24-27(16-6-2-3-7-16)21(17)23-15-22-20/h4-5,8-9,14-16H,2-3,6-7,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152743 (CHEMBL3781308) Show SMILES COc1ccccc1N1CCN(CC1C)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-17-15-27(12-13-28(17)20-10-6-7-11-21(20)30-2)22-19-14-26-29(23(19)25-16-24-22)18-8-4-3-5-9-18/h3-11,14,16-17H,12-13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538374 (CHEMBL4637134) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H33N7O2/c1-3-22(4-2)33-27(37)18-38-24-7-5-6-20(14-24)28-35-26-12-13-30-17-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h5-11,14-16,22,30H,3-4,12-13,17-18H2,1-2H3,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538373 (CHEMBL4635564) Show SMILES O=C(COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C29H31N7O2/c37-27(33-22-5-1-2-6-22)18-38-24-7-3-4-20(14-24)28-35-26-12-13-30-17-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h3-4,7-11,14-16,22,30H,1-2,5-6,12-13,17-18H2,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538389 (CHEMBL4634012) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCOC1 Show InChI InChI=1S/C32H37N7O3/c1-32(2,3)38-29(40)20-42-26-6-4-5-22(15-26)30-36-28-11-13-39(25-12-14-41-19-25)18-27(28)31(37-30)35-24-9-7-21(8-10-24)23-16-33-34-17-23/h4-10,15-17,25H,11-14,18-20H2,1-3H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453248 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES FC(F)(F)CNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C25H21F3N6O3/c26-25(27,28)14-29-22(35)13-37-19-3-1-2-16(8-19)23-33-21-12-36-11-20(21)24(34-23)32-18-6-4-15(5-7-18)17-9-30-31-10-17/h1-10H,11-14H2,(H,29,35)(H,30,31)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155672 (CHEMBL3781183) Show SMILES COc1cc(ccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-13-17(14-24)7-8-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155679 (CHEMBL3780772) Show SMILES COc1cccc(c1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-18-7-5-6-17(14-18)29-23-19(15-26-29)22(24-16-25-23)28-12-10-27(11-13-28)20-8-3-4-9-21(20)31-2/h3-9,14-16H,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155749 (CHEMBL3781625) Show SMILES COc1ccc(cc1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-18-9-7-17(8-10-18)29-23-19(15-26-29)22(24-16-25-23)28-13-11-27(12-14-28)20-5-3-4-6-21(20)31-2/h3-10,15-16H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538390 (CHEMBL4638542) Show SMILES COCCN1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H37N7O3/c1-31(2,3)37-28(39)20-41-25-7-5-6-22(16-25)29-35-27-12-13-38(14-15-40-4)19-26(27)30(36-29)34-24-10-8-21(9-11-24)23-17-32-33-18-23/h5-11,16-18H,12-15,19-20H2,1-4H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538386 (CHEMBL4647401) Show SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C32H35N7O2/c1-32(13-14-32)38-29(40)20-41-26-7-2-4-22(16-26)30-36-28-12-15-39(25-5-3-6-25)19-27(28)31(37-30)35-24-10-8-21(9-11-24)23-17-33-34-18-23/h2,4,7-11,16-18,25H,3,5-6,12-15,19-20H2,1H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155747 (CHEMBL3781194) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-5-3-2-4-20(21)28-10-12-29(13-11-28)22-19-15-27-30(23(19)26-16-25-22)18-8-6-17(14-24)7-9-18/h2-9,15-16H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538383 (CHEMBL4645036) Show SMILES CC1(CC1)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CC1 Show InChI InChI=1S/C31H33N7O2/c1-31(12-13-31)37-28(39)19-40-25-4-2-3-21(15-25)29-35-27-11-14-38(24-9-10-24)18-26(27)30(36-29)34-23-7-5-20(6-8-23)22-16-32-33-17-22/h2-8,15-17,24H,9-14,18-19H2,1H3,(H,32,33)(H,37,39)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538382 (CHEMBL4649311) Show SMILES CC(CF)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C31H36FN7O2/c1-20(15-32)39-13-12-27-26(18-39)30(35-24-10-8-21(9-11-24)23-16-33-34-17-23)37-29(36-27)22-6-5-7-25(14-22)41-19-28(40)38-31(2,3)4/h5-11,14,16-17,20H,12-13,15,18-19H2,1-4H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	232	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM453219 (US10729691, Example 4) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CC1 Show InChI InChI=1S/C26H24N6O3/c33-24(29-19-8-9-19)15-35-21-3-1-2-17(10-21)25-31-23-14-34-13-22(23)26(32-25)30-20-6-4-16(5-7-20)18-11-27-28-12-18/h1-7,10-12,19H,8-9,13-15H2,(H,27,28)(H,29,33)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538387 (CHEMBL4642809) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C31H35N7O2/c1-20(2)34-29(39)19-40-26-8-3-5-22(15-26)30-36-28-13-14-38(25-6-4-7-25)18-27(28)31(37-30)35-24-11-9-21(10-12-24)23-16-32-33-17-23/h3,5,8-12,15-17,20,25H,4,6-7,13-14,18-19H2,1-2H3,(H,32,33)(H,34,39)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155714 (CHEMBL3781157) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H25Br2ClN4O/c27-19-10-18-7-6-17-11-20(29)12-21(28)23(17)25(24(18)31-15-19)33-9-2-1-5-22(33)26(34)32-14-16-4-3-8-30-13-16/h3-4,8,10-13,15,22,25H,1-2,5-7,9,14H2,(H,32,34)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152826 (CHEMBL3781347) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1C Show InChI InChI=1S/C23H24N6O/c1-17-7-3-4-8-19(17)29-23-18(15-26-29)22(24-16-25-23)28-13-11-27(12-14-28)20-9-5-6-10-21(20)30-2/h3-10,15-16H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538391 (CHEMBL4642046) Show SMILES COCC(C)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C32H39N7O3/c1-21(19-41-5)39-14-13-28-27(18-39)31(35-25-11-9-22(10-12-25)24-16-33-34-17-24)37-30(36-28)23-7-6-8-26(15-23)42-20-29(40)38-32(2,3)4/h6-12,15-17,21H,13-14,18-20H2,1-5H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538385 (CHEMBL4632395) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C1CCC1 Show InChI InChI=1S/C32H37N7O2/c1-32(2,3)38-29(40)20-41-26-9-4-6-22(16-26)30-36-28-14-15-39(25-7-5-8-25)19-27(28)31(37-30)35-24-12-10-21(11-13-24)23-17-33-34-18-23/h4,6,9-13,16-18,25H,5,7-8,14-15,19-20H2,1-3H3,(H,33,34)(H,38,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	287	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538365 (CHEMBL4632920) Show SMILES CCCNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C26H26N6O3/c1-2-10-27-24(33)16-35-21-5-3-4-18(11-21)25-31-23-15-34-14-22(23)26(32-25)30-20-8-6-17(7-9-20)19-12-28-29-13-19/h3-9,11-13H,2,10,14-16H2,1H3,(H,27,33)(H,28,29)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155753 (CHEMBL3780470) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cc(F)ccc1OC Show InChI InChI=1S/C23H23FN6O2/c1-31-20-6-4-3-5-18(20)28-9-11-29(12-10-28)22-17-14-27-30(23(17)26-15-25-22)19-13-16(24)7-8-21(19)32-2/h3-8,13-15H,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155681 (CHEMBL3781827) Show SMILES COc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6O/c1-29-19-9-5-8-18(14-19)26-10-12-27(13-11-26)21-20-15-25-28(22(20)24-16-23-21)17-6-3-2-4-7-17/h2-9,14-16H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538368 (CHEMBL4649877) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)Nc1ccccc1 Show InChI InChI=1S/C29H24N6O3/c36-27(32-22-6-2-1-3-7-22)18-38-24-8-4-5-20(13-24)28-34-26-17-37-16-25(26)29(35-28)33-23-11-9-19(10-12-23)21-14-30-31-15-21/h1-15H,16-18H2,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155750 (CHEMBL3780595) Show SMILES COc1ccc(cn1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C22H23N7O2/c1-30-19-6-4-3-5-18(19)27-9-11-28(12-10-27)21-17-14-26-29(22(17)25-15-24-21)16-7-8-20(31-2)23-13-16/h3-8,13-15H,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50155677 (CHEMBL3780765) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(c1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-3-2-7-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-6-4-5-17(13-18)14-24/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50538372 (CHEMBL4637262) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCNCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H29N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-10-11-28-15-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-9,12-14,17,28H,10-11,15-16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair

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