Found 10 hits Enz. Inhib. hit(s) with all data for entry = 50002337 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50002831
((2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahyd...)Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021521
(2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrah...)Show SMILES COc1ccc(cc1OC)C1O[C@H]([C@@H](C)[C@H]1C)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14+,21+,22?/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021520
(2,5-Bis-(3,4-dimethoxy-phenyl)-tetrahydro-furan | ...)Show SMILES COc1ccc(cc1OC)[C@H]1CC[C@@H](O1)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C20H24O5/c1-21-17-7-5-13(11-19(17)23-3)15-9-10-16(25-15)14-6-8-18(22-2)20(12-14)24-4/h5-8,11-12,15-16H,9-10H2,1-4H3/t15-,16-/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021515
(2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrah...)Show SMILES COc1ccc(cc1OC)C1O[C@H]([C@@H](C)[C@@H]1C)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14-,21+,22?/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021517
(2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrah...)Show SMILES COc1ccc(cc1OC)[C@@H]1O[C@H]([C@H](C)[C@@H]1C)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14+,21-,22-/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021518
(2,5-Bis-(3,4-dimethoxy-phenyl)-tetrahydro-furan | ...)Show SMILES COc1ccc(cc1OC)C1CC[C@@H](O1)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C20H24O5/c1-21-17-7-5-13(11-19(17)23-3)15-9-10-16(25-15)14-6-8-18(22-2)20(12-14)24-4/h5-8,11-12,15-16H,9-10H2,1-4H3/t15-,16?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021519
(2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrah...)Show SMILES COc1ccc(cc1OC)[C@H]1O[C@H]([C@H](C)[C@@H]1C)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14+,21-,22+ | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021522
(2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrah...)Show SMILES COc1ccc(cc1OC)[C@H]1O[C@@H]([C@@H](C)[C@@H]1C)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14-,21-,22-/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021514
(2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrah...)Show SMILES COc1ccc(cc1OC)[C@@H]1O[C@H]([C@@H](C)[C@@H]1C)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14-,21+,22+/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50021516
(2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan...)Show SMILES COc1cc(cc(OC)c1OC)C1CC[C@@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PAF receptor binding to rabbit platelet plasma membranes |
J Med Chem 29: 1917-21 (1986)
BindingDB Entry DOI: 10.7270/Q2X63KZS |
More data for this
Ligand-Target Pair | |
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