Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50013647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132898 (CHEMBL115142 | Dibutyl-[3-(2,4-dichloro-phenyl)-1,...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4/c1-5-7-11-28(12-8-6-2)19-13-15(3)25-21-20(26-27(4)22(19)21)17-10-9-16(23)14-18(17)24/h9-10,13-14H,5-8,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132950 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H30Cl2N4/c1-5-7-9-13-29(12-8-6-2)20-14-16(3)26-22-21(27-28(4)23(20)22)18-11-10-17(24)15-19(18)25/h10-11,14-15H,5-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132924 (CHEMBL116171 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H30Cl2N4/c1-4-5-6-7-12-30(15-17-8-9-17)21-13-16(2)27-23-22(28-29(3)24(21)23)19-11-10-18(25)14-20(19)26/h10-11,13-14,17H,4-9,12,15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132913 (CHEMBL323886 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCCCN(CCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4/c1-5-7-8-12-28(11-6-2)19-13-15(3)25-21-20(26-27(4)22(19)21)17-10-9-16(23)14-18(17)24/h9-10,13-14H,5-8,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132927 (Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1...) Show SMILES CCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H26Cl2N4/c1-4-5-10-28(13-15-6-7-15)19-11-14(2)25-21-20(26-27(3)22(19)21)17-9-8-16(23)12-18(17)24/h8-9,11-12,15H,4-7,10,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132921 (CHEMBL112626 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCCCN(CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4/c1-5-7-8-11-27(6-2)18-12-14(3)24-20-19(25-26(4)21(18)20)16-10-9-15(22)13-17(16)23/h9-10,12-13H,5-8,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132914 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CCSC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4S/c1-5-6-9-27(10-11-28-4)18-12-14(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)13-17(16)23/h7-8,12-13H,5-6,9-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132923 (CHEMBL326156 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H28Cl2N4/c1-4-5-6-11-29(14-16-7-8-16)20-12-15(2)26-22-21(27-28(3)23(20)22)18-10-9-17(24)13-19(18)25/h9-10,12-13,16H,4-8,11,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132901 (CHEMBL445075 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H24Cl2N4/c1-4-9-27(12-14-5-6-14)18-10-13(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)11-17(16)23/h7-8,10-11,14H,4-6,9,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132892 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4/c1-5-7-10-26(6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-9-8-14(21)12-16(15)22/h8-9,11-12H,5-7,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132934 (CHEMBL324728 | Dibutyl-[3-(2-chloro-4,6-dimethyl-p...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1c(C)cc(C)cc1Cl |(15.65,1.54,;14.64,.39,;13.12,.69,;12.1,-.45,;10.59,-.15,;10.1,1.31,;11.11,2.47,;10.64,3.93,;11.65,5.09,;9.56,-1.31,;10.04,-2.77,;9.01,-3.91,;9.5,-5.39,;7.51,-3.6,;7.02,-2.14,;5.62,-1.52,;5.78,.02,;7.28,.34,;7.91,1.75,;8.05,-.99,;4.29,-2.3,;4.29,-3.84,;5.63,-4.61,;2.95,-4.61,;1.62,-3.84,;.28,-4.61,;1.62,-2.3,;2.95,-1.53,;2.95,.02,)| Show InChI InChI=1S/C24H33ClN4/c1-7-9-11-29(12-10-8-2)20-15-18(5)26-23-22(27-28(6)24(20)23)21-17(4)13-16(3)14-19(21)25/h13-15H,7-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132912 (CHEMBL114273 | Dibutyl-[3-(2-chloro-4-methyl-pheny...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(C)cc1Cl Show InChI InChI=1S/C23H31ClN4/c1-6-8-12-28(13-9-7-2)20-15-17(4)25-22-21(26-27(5)23(20)22)18-11-10-16(3)14-19(18)24/h10-11,14-15H,6-9,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132926 (CHEMBL112290 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-5-25(8-9-26-4)16-10-12(2)22-18-17(23-24(3)19(16)18)14-7-6-13(20)11-15(14)21/h6-7,10-11H,5,8-9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132896 (CHEMBL114193 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(CCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4/c1-5-9-26(10-6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132943 (CHEMBL112560 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CC(C)CN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H26Cl2N4/c1-13(2)11-28(12-15-5-6-15)19-9-14(3)25-21-20(26-27(4)22(19)21)17-8-7-16(23)10-18(17)24/h7-10,13,15H,5-6,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132944 (CHEMBL111838 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCCCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H30Cl2N4O/c1-5-6-7-8-11-29(12-13-30-4)20-14-16(2)26-22-21(27-28(3)23(20)22)18-10-9-17(24)15-19(18)25/h9-10,14-15H,5-8,11-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132938 (CHEMBL112031 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4/c1-5-9-25(6-2)16-10-12(3)22-18-17(23-24(4)19(16)18)14-8-7-13(20)11-15(14)21/h7-8,10-11H,5-6,9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132942 (2-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazo...) Show SMILES CCCN(CCO)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-4-7-25(8-9-26)16-10-12(2)22-18-17(23-24(3)19(16)18)14-6-5-13(20)11-15(14)21/h5-6,10-11,26H,4,7-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132932 (CHEMBL332721 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H22Cl2N4/c1-4-26(11-13-5-6-13)17-9-12(2)23-19-18(24-25(3)20(17)19)15-8-7-14(21)10-16(15)22/h7-10,13H,4-6,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132948 (CHEMBL115349 | Dibutyl-[3-(2-chloro-4-methoxy-phen...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(OC)cc1Cl Show InChI InChI=1S/C23H31ClN4O/c1-6-8-12-28(13-9-7-2)20-14-16(3)25-22-21(26-27(4)23(20)22)18-11-10-17(29-5)15-19(18)24/h10-11,14-15H,6-9,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132916 (CHEMBL117209 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4O/c1-5-8-26(9-10-27-4)17-11-13(2)23-19-18(24-25(3)20(17)19)15-7-6-14(21)12-16(15)22/h6-7,11-12H,5,8-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132935 (CHEMBL112264 | Dibutyl-[1,5-dimethyl-3-(2,4,6-trim...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1c(C)cc(C)cc1C |(15.65,1.54,;14.64,.39,;13.12,.69,;12.1,-.45,;10.59,-.15,;10.1,1.31,;11.11,2.47,;10.64,3.93,;11.65,5.09,;9.56,-1.31,;10.04,-2.77,;9.01,-3.91,;9.5,-5.39,;7.51,-3.6,;7.02,-2.14,;5.62,-1.52,;5.78,.02,;7.28,.34,;7.91,1.75,;8.05,-.99,;4.29,-2.3,;4.29,-3.84,;5.63,-4.61,;2.95,-4.61,;1.62,-3.84,;.28,-4.61,;1.62,-2.3,;2.95,-1.53,;2.95,.02,)| Show InChI InChI=1S/C25H36N4/c1-8-10-12-29(13-11-9-2)21-16-20(6)26-24-23(27-28(7)25(21)24)22-18(4)14-17(3)15-19(22)5/h14-16H,8-13H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132928 (CHEMBL112336 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4O/c1-5-6-7-10-28(11-12-29-4)19-13-15(2)25-21-20(26-27(3)22(19)21)17-9-8-16(23)14-18(17)24/h8-9,13-14H,5-7,10-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132922 (CHEMBL326284 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCCN(C(CC)CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H30Cl2N4/c1-6-9-12-29(17(7-2)8-3)20-13-15(4)26-22-21(27-28(5)23(20)22)18-11-10-16(24)14-19(18)25/h10-11,13-14,17H,6-9,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132930 (CHEMBL325918 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES COCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4O2/c1-13-11-17(26(7-9-27-3)8-10-28-4)20-19(23-13)18(24-25(20)2)15-6-5-14(21)12-16(15)22/h5-6,11-12H,7-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132917 (CHEMBL325051 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES COCCN(C(C)C)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4O/c1-12(2)26(8-9-27-5)17-10-13(3)23-19-18(24-25(4)20(17)19)15-7-6-14(21)11-16(15)22/h6-7,10-12H,8-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132915 (CHEMBL112045 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(CCCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4O/c1-5-9-27(10-6-11-28-4)18-12-14(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)13-17(16)23/h7-8,12-13H,5-6,9-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132936 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4O/c1-5-6-9-27(10-11-28-4)18-12-14(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)13-17(16)23/h7-8,12-13H,5-6,9-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132918 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CC1CCCO1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H28Cl2N4O/c1-4-5-10-29(14-17-7-6-11-30-17)20-12-15(2)26-22-21(27-28(3)23(20)22)18-9-8-16(24)13-19(18)25/h8-9,12-13,17H,4-7,10-11,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132945 (CHEMBL448788 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES COCCN(CC(C)C)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4O/c1-13(2)12-27(8-9-28-5)18-10-14(3)24-20-19(25-26(4)21(18)20)16-7-6-15(22)11-17(16)23/h6-7,10-11,13H,8-9,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132920 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CCc1ccccn1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C25H27Cl2N5/c1-4-5-13-32(14-11-19-8-6-7-12-28-19)22-15-17(2)29-24-23(30-31(3)25(22)24)20-10-9-18(26)16-21(20)27/h6-10,12,15-16H,4-5,11,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132925 (CHEMBL115820 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCN(CCCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4O/c1-5-26(9-6-10-27-4)17-11-13(2)23-19-18(24-25(3)20(17)19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132946 (4-({[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyraz...) Show SMILES CCCN(Cc1ccc(O)cc1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H24Cl2N4O/c1-4-11-30(14-16-5-8-18(31)9-6-16)21-12-15(2)27-23-22(28-29(3)24(21)23)19-10-7-17(25)13-20(19)26/h5-10,12-13,31H,4,11,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132919 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CCCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4O/c1-5-6-10-28(11-7-12-29-4)19-13-15(2)25-21-20(26-27(3)22(19)21)17-9-8-16(23)14-18(17)24/h8-9,13-14H,5-7,10-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132949 (CHEMBL116003 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(C)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C18H20Cl2N4/c1-5-8-23(3)15-9-11(2)21-17-16(22-24(4)18(15)17)13-7-6-12(19)10-14(13)20/h6-7,9-10H,5,8H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132937 (CHEMBL111960 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES COCCN(C)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C18H20Cl2N4O/c1-11-9-15(23(2)7-8-25-4)18-17(21-11)16(22-24(18)3)13-6-5-12(19)10-14(13)20/h5-6,9-10H,7-8H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132941 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CCc1ccncc1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C25H27Cl2N5/c1-4-5-13-32(14-10-18-8-11-28-12-9-18)22-15-17(2)29-24-23(30-31(3)25(22)24)20-7-6-19(26)16-21(20)27/h6-9,11-12,15-16H,4-5,10,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132940 (2-[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazol...) Show SMILES CCCC(CO)Nc1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-4-5-13(10-26)23-16-8-11(2)22-18-17(24-25(3)19(16)18)14-7-6-12(20)9-15(14)21/h6-9,13,26H,4-5,10H2,1-3H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132931 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(Cc1ccncc1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H25Cl2N5/c1-4-5-12-31(15-17-8-10-27-11-9-17)21-13-16(2)28-23-22(29-30(3)24(21)23)19-7-6-18(25)14-20(19)26/h6-11,13-14H,4-5,12,15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132929 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCNc1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C18H20Cl2N4/c1-4-5-8-21-15-9-11(2)22-17-16(23-24(3)18(15)17)13-7-6-12(19)10-14(13)20/h6-7,9-10H,4-5,8H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132933 (CHEMBL112549 | Dibutyl-[3-(4-chloro-phenyl)-1,5-di...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H29ClN4/c1-5-7-13-27(14-8-6-2)19-15-16(3)24-21-20(25-26(4)22(19)21)17-9-11-18(23)12-10-17/h9-12,15H,5-8,13-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132947 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CC1CCCN1C)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H31Cl2N5/c1-5-6-12-31(15-18-8-7-11-29(18)3)21-13-16(2)27-23-22(28-30(4)24(21)23)19-10-9-17(25)14-20(19)26/h9-10,13-14,18H,5-8,11-12,15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132939 (4-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazo...) Show SMILES Cc1cc(NCc2ccc(O)cc2)c2n(C)nc(-c3ccc(Cl)cc3Cl)c2n1 Show InChI InChI=1S/C21H18Cl2N4O/c1-12-9-18(24-11-13-3-6-15(28)7-4-13)21-20(25-12)19(26-27(21)2)16-8-5-14(22)10-17(16)23/h3-10,28H,11H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132927 (Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1...) Show SMILES CCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H26Cl2N4/c1-4-5-10-28(13-15-6-7-15)19-11-14(2)25-21-20(26-27(3)22(19)21)17-9-8-16(23)12-18(17)24/h8-9,11-12,15H,4-7,10,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132898 (CHEMBL115142 | Dibutyl-[3-(2,4-dichloro-phenyl)-1,...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4/c1-5-7-11-28(12-8-6-2)19-13-15(3)25-21-20(26-27(4)22(19)21)17-10-9-16(23)14-18(17)24/h9-10,13-14H,5-8,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132926 (CHEMBL112290 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-5-25(8-9-26-4)16-10-12(2)22-18-17(23-24(3)19(16)18)14-7-6-13(20)11-15(14)21/h6-7,10-11H,5,8-9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132892 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4/c1-5-7-10-26(6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-9-8-14(21)12-16(15)22/h8-9,11-12H,5-7,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132901 (CHEMBL445075 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H24Cl2N4/c1-4-9-27(12-14-5-6-14)18-10-13(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)11-17(16)23/h7-8,10-11,14H,4-6,9,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132942 (2-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazo...) Show SMILES CCCN(CCO)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-4-7-25(8-9-26)16-10-12(2)22-18-17(23-24(3)19(16)18)14-6-5-13(20)11-15(14)21/h5-6,10-11,26H,4,7-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of (Corticotropin-Releasing Factor Receptor) CRF-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132916 (CHEMBL117209 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4O/c1-5-8-26(9-10-27-4)17-11-13(2)23-19-18(24-25(3)20(17)19)15-7-6-14(21)12-16(15)22/h6-7,11-12H,5,8-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair

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