Compile Data Set for Download or QSAR

Found 154 hits Enz. Inhib. hit(s) with all data for entry = 50016710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 1B receptor				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against 5-hydroxytryptamine 2A receptor				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against histamine H2 receptor				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172441 ((E)-N-{2-[(2-Hydroxy-ethyl)-methyl-amino]-4-methyl...) Show SMILES CN(CCO)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C23H22F3N3O3/c1-15-13-21(29(2)11-12-30)28-20-9-6-17(14-19(15)20)27-22(31)10-5-16-3-7-18(8-4-16)32-23(24,25)26/h3-10,13-14,30H,11-12H2,1-2H3,(H,27,31)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172429 (CHEMBL370120 | N-(4-Methyl-2-piperidin-1-yl-quinol...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCCCC1 Show InChI InChI=1S/C24H24F3N3O3/c1-16-13-22(30-11-3-2-4-12-30)29-21-10-5-17(14-20(16)21)28-23(31)15-32-18-6-8-19(9-7-18)33-24(25,26)27/h5-10,13-14H,2-4,11-12,15H2,1H3,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against dopamine receptor D3				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172418 (CHEMBL195635 | N-[4-Methyl-2-(4-pyrrolidin-1-yl-pi...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCC1 Show InChI InChI=1S/C28H31F3N4O3/c1-19-16-26(35-14-10-21(11-15-35)34-12-2-3-13-34)33-25-9-4-20(17-24(19)25)32-27(36)18-37-22-5-7-23(8-6-22)38-28(29,30)31/h4-9,16-17,21H,2-3,10-15,18H2,1H3,(H,32,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172425 (CHEMBL197026 | N-[2-(4-Amino-piperidin-1-yl)-4-met...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(N)CC1 Show InChI InChI=1S/C24H25F3N4O3/c1-15-12-22(31-10-8-16(28)9-11-31)30-21-7-2-17(13-20(15)21)29-23(32)14-33-18-3-5-19(6-4-18)34-24(25,26)27/h2-7,12-13,16H,8-11,14,28H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172424 (CHEMBL198361 | N-(4-Methyl-2-morpholin-4-yl-quinol...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCOCC1 Show InChI InChI=1S/C23H22F3N3O4/c1-15-12-21(29-8-10-31-11-9-29)28-20-7-2-16(13-19(15)20)27-22(30)14-32-17-3-5-18(6-4-17)33-23(24,25)26/h2-7,12-13H,8-11,14H2,1H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against muscarinic acetylcholine receptor M1				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172416 (CHEMBL427540 | N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CC2CC1CN2 Show InChI InChI=1S/C24H23F3N4O3/c1-14-8-22(31-12-16-9-17(31)11-28-16)30-21-7-2-15(10-20(14)21)29-23(32)13-33-18-3-5-19(6-4-18)34-24(25,26)27/h2-8,10,16-17,28H,9,11-13H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172415 (2-(2,4-Dichloro-phenoxy)-N-{2-[(2-hydroxy-ethyl)-m...) Show SMILES CN(CCO)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C21H21Cl2N3O3/c1-13-9-20(26(2)7-8-27)25-18-5-4-15(11-16(13)18)24-21(28)12-29-19-6-3-14(22)10-17(19)23/h3-6,9-11,27H,7-8,12H2,1-2H3,(H,24,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172444 ((E)-N-[2-(4-Ethyl-piperazin-1-yl)-4-methyl-quinoli...) Show SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C26H27F3N4O2/c1-3-32-12-14-33(15-13-32)24-16-18(2)22-17-20(7-10-23(22)31-24)30-25(34)11-6-19-4-8-21(9-5-19)35-26(27,28)29/h4-11,16-17H,3,12-15H2,1-2H3,(H,30,34)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172434 (Acetic acid 2-({6-[2-(3,4-dichloro-phenoxy)-acetyl...) Show SMILES CN(CCOC(C)=O)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C23H23Cl2N3O4/c1-14-10-22(28(3)8-9-31-15(2)29)27-20-6-5-17(12-18(14)20)26-23(30)13-32-21-7-4-16(24)11-19(21)25/h4-7,10-12H,8-9,13H2,1-3H3,(H,26,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50150073 (CHEMBL184084 | N-(4-methyl-2-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1cc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C24H25F3N4O3/c1-16-13-22(31-11-9-30(2)10-12-31)29-21-8-3-17(14-20(16)21)28-23(32)15-33-18-4-6-19(7-5-18)34-24(25,26)27/h3-8,13-14H,9-12,15H2,1-2H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172427 (CHEMBL196581 | N-[2-(3-Dimethylamino-propylamino)-...) Show SMILES CN(C)CCCNc1cc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C24H27F3N4O3/c1-16-13-22(28-11-4-12-31(2)3)30-21-10-5-17(14-20(16)21)29-23(32)15-33-18-6-8-19(9-7-18)34-24(25,26)27/h5-10,13-14H,4,11-12,15H2,1-3H3,(H,28,30)(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172442 ((E)-N-[2-(2-Dimethylamino-ethylamino)-4-methyl-qui...) Show SMILES CN(C)CCNc1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C24H25F3N4O2/c1-16-14-22(28-12-13-31(2)3)30-21-10-7-18(15-20(16)21)29-23(32)11-6-17-4-8-19(9-5-17)33-24(25,26)27/h4-11,14-15H,12-13H2,1-3H3,(H,28,30)(H,29,32)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172425 (CHEMBL197026 | N-[2-(4-Amino-piperidin-1-yl)-4-met...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(N)CC1 Show InChI InChI=1S/C24H25F3N4O3/c1-15-12-22(31-10-8-16(28)9-11-31)30-21-7-2-17(13-20(15)21)29-23(32)14-33-18-3-5-19(6-4-18)34-24(25,26)27/h2-7,12-13,16H,8-11,14,28H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against histamine H1 receptor				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172440 (2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12)N1CCNCC1 Show InChI InChI=1S/C22H22Cl2N4O2/c1-14-10-21(28-8-6-25-7-9-28)27-19-4-3-16(12-17(14)19)26-22(29)13-30-20-5-2-15(23)11-18(20)24/h2-5,10-12,25H,6-9,13H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172427 (CHEMBL196581 | N-[2-(3-Dimethylamino-propylamino)-...) Show SMILES CN(C)CCCNc1cc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C24H27F3N4O3/c1-16-13-22(28-11-4-12-31(2)3)30-21-10-5-17(14-20(16)21)29-23(32)15-33-18-6-8-19(9-7-18)34-24(25,26)27/h5-10,13-14H,4,11-12,15H2,1-3H3,(H,28,30)(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172430 ((E)-N-(4-Methyl-2-piperazin-1-yl-quinolin-6-yl)-3-...) Show SMILES Cc1cc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCNCC1 Show InChI InChI=1S/C24H23F3N4O2/c1-16-14-22(31-12-10-28-11-13-31)30-21-8-5-18(15-20(16)21)29-23(32)9-4-17-2-6-19(7-3-17)33-24(25,26)27/h2-9,14-15,28H,10-13H2,1H3,(H,29,32)/b9-4+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172426 ((E)-N-[2-(2-Dimethylamino-1-methyl-ethylamino)-4-m...) Show SMILES CC(CN(C)C)Nc1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C25H27F3N4O2/c1-16-13-23(29-17(2)15-32(3)4)31-22-11-8-19(14-21(16)22)30-24(33)12-7-18-5-9-20(10-6-18)34-25(26,27)28/h5-14,17H,15H2,1-4H3,(H,29,31)(H,30,33)/b12-7+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172432 (2-(2,4-Dichloro-phenoxy)-N-{2-[(2-dimethylamino-et...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C23H26Cl2N4O2/c1-15-11-22(29(4)10-9-28(2)3)27-20-7-6-17(13-18(15)20)26-23(30)14-31-21-8-5-16(24)12-19(21)25/h5-8,11-13H,9-10,14H2,1-4H3,(H,26,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against muscarinic acetylcholine receptor M2				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172425 (CHEMBL197026 | N-[2-(4-Amino-piperidin-1-yl)-4-met...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(N)CC1 Show InChI InChI=1S/C24H25F3N4O3/c1-15-12-22(31-10-8-16(28)9-11-31)30-21-7-2-17(13-20(15)21)29-23(32)14-33-18-3-5-19(6-4-18)34-24(25,26)27/h2-7,12-13,16H,8-11,14,28H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172440 (2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12)N1CCNCC1 Show InChI InChI=1S/C22H22Cl2N4O2/c1-14-10-21(28-8-6-25-7-9-28)27-19-4-3-16(12-17(14)19)26-22(29)13-30-20-5-2-15(23)11-18(20)24/h2-5,10-12,25H,6-9,13H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172441 ((E)-N-{2-[(2-Hydroxy-ethyl)-methyl-amino]-4-methyl...) Show SMILES CN(CCO)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C23H22F3N3O3/c1-15-13-21(29(2)11-12-30)28-20-9-6-17(14-19(15)20)27-22(31)10-5-16-3-7-18(8-4-16)32-23(24,25)26/h3-10,13-14,30H,11-12H2,1-2H3,(H,27,31)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]-myo-inositol				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172443 (2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-morpholin-4...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc12)N1CCOCC1 Show InChI InChI=1S/C22H21Cl2N3O3/c1-14-10-21(27-6-8-29-9-7-27)26-19-4-3-16(12-17(14)19)25-22(28)13-30-20-5-2-15(23)11-18(20)24/h2-5,10-12H,6-9,13H2,1H3,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172432 (2-(2,4-Dichloro-phenoxy)-N-{2-[(2-dimethylamino-et...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C23H26Cl2N4O2/c1-15-11-22(29(4)10-9-28(2)3)27-20-7-6-17(13-18(15)20)26-23(30)14-31-21-8-5-16(24)12-19(21)25/h5-8,11-13H,9-10,14H2,1-4H3,(H,26,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172436 ((E)-N-(2-[1,4]Diazepan-1-yl-4-methyl-quinolin-6-yl...) Show SMILES Cc1cc(nc2ccc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)cc12)N1CCCNCC1 Show InChI InChI=1S/C25H25F3N4O2/c1-17-15-23(32-13-2-11-29-12-14-32)31-22-9-6-19(16-21(17)22)30-24(33)10-5-18-3-7-20(8-4-18)34-25(26,27)28/h3-10,15-16,29H,2,11-14H2,1H3,(H,30,33)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172413 (2-(2,4-Dichloro-phenoxy)-N-{4-methyl-2-[methyl-(2-...) Show SMILES CNCCN(C)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H24Cl2N4O2/c1-14-10-21(28(3)9-8-25-2)27-19-6-5-16(12-17(14)19)26-22(29)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12,25H,8-9,13H2,1-3H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172418 (CHEMBL195635 | N-[4-Methyl-2-(4-pyrrolidin-1-yl-pi...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCC1 Show InChI InChI=1S/C28H31F3N4O3/c1-19-16-26(35-14-10-21(11-15-35)34-12-2-3-13-34)33-25-9-4-20(17-24(19)25)32-27(36)18-37-22-5-7-23(8-6-22)38-28(29,30)31/h4-9,16-17,21H,2-3,10-15,18H2,1H3,(H,32,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172441 ((E)-N-{2-[(2-Hydroxy-ethyl)-methyl-amino]-4-methyl...) Show SMILES CN(CCO)c1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C23H22F3N3O3/c1-15-13-21(29(2)11-12-30)28-20-9-6-17(14-19(15)20)27-22(31)10-5-16-3-7-18(8-4-16)32-23(24,25)26/h3-10,13-14,30H,11-12H2,1-2H3,(H,27,31)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50150709 (2-(2,4-Dichloro-phenoxy)-N-[4-methyl-2-(4-methyl-p...) Show SMILES CN1CCN(CC1)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C23H24Cl2N4O2/c1-15-11-22(29-9-7-28(2)8-10-29)27-20-5-4-17(13-18(15)20)26-23(30)14-31-21-6-3-16(24)12-19(21)25/h3-6,11-13H,7-10,14H2,1-2H3,(H,26,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172416 (CHEMBL427540 | N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CC2CC1CN2 Show InChI InChI=1S/C24H23F3N4O3/c1-14-8-22(31-12-16-9-17(31)11-28-16)30-21-7-2-15(10-20(14)21)29-23(32)13-33-18-3-5-19(6-4-18)34-24(25,26)27/h2-8,10,16-17,28H,9,11-13H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172413 (2-(2,4-Dichloro-phenoxy)-N-{4-methyl-2-[methyl-(2-...) Show SMILES CNCCN(C)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H24Cl2N4O2/c1-14-10-21(28(3)9-8-25-2)27-19-6-5-16(12-17(14)19)26-22(29)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12,25H,8-9,13H2,1-3H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172413 (2-(2,4-Dichloro-phenoxy)-N-{4-methyl-2-[methyl-(2-...) Show SMILES CNCCN(C)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H24Cl2N4O2/c1-14-10-21(28(3)9-8-25-2)27-19-6-5-16(12-17(14)19)26-22(29)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12,25H,8-9,13H2,1-3H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172418 (CHEMBL195635 | N-[4-Methyl-2-(4-pyrrolidin-1-yl-pi...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCC1 Show InChI InChI=1S/C28H31F3N4O3/c1-19-16-26(35-14-10-21(11-15-35)34-12-2-3-13-34)33-25-9-4-20(17-24(19)25)32-27(36)18-37-22-5-7-23(8-6-22)38-28(29,30)31/h4-9,16-17,21H,2-3,10-15,18H2,1H3,(H,32,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172427 (CHEMBL196581 | N-[2-(3-Dimethylamino-propylamino)-...) Show SMILES CN(C)CCCNc1cc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C24H27F3N4O3/c1-16-13-22(28-11-4-12-31(2)3)30-21-10-5-17(14-20(16)21)29-23(32)15-33-18-6-8-19(9-7-18)34-24(25,26)27/h5-10,13-14H,4,11-12,15H2,1-3H3,(H,28,30)(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against dopamine receptor D1				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172418 (CHEMBL195635 | N-[4-Methyl-2-(4-pyrrolidin-1-yl-pi...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(CC1)N1CCCC1 Show InChI InChI=1S/C28H31F3N4O3/c1-19-16-26(35-14-10-21(11-15-35)34-12-2-3-13-34)33-25-9-4-20(17-24(19)25)32-27(36)18-37-22-5-7-23(8-6-22)38-28(29,30)31/h4-9,16-17,21H,2-3,10-15,18H2,1H3,(H,32,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]-myo-inositol				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172442 ((E)-N-[2-(2-Dimethylamino-ethylamino)-4-methyl-qui...) Show SMILES CN(C)CCNc1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C24H25F3N4O2/c1-16-14-22(28-12-13-31(2)3)30-21-10-7-18(15-20(16)21)29-23(32)11-6-17-4-8-19(9-5-17)33-24(25,26)27/h4-11,14-15H,12-13H2,1-3H3,(H,28,30)(H,29,32)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172438 (CHEMBL194691 | N-{2-[(1-Ethyl-pyrrolidin-2-ylmethy...) Show SMILES CCN1CCCC1CNc1cc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C26H29F3N4O3/c1-3-33-12-4-5-19(33)15-30-24-13-17(2)22-14-18(6-11-23(22)32-24)31-25(34)16-35-20-7-9-21(10-8-20)36-26(27,28)29/h6-11,13-14,19H,3-5,12,15-16H2,1-2H3,(H,30,32)(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172432 (2-(2,4-Dichloro-phenoxy)-N-{2-[(2-dimethylamino-et...) Show SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C23H26Cl2N4O2/c1-15-11-22(29(4)10-9-28(2)3)27-20-7-6-17(13-18(15)20)26-23(30)14-31-21-8-5-16(24)12-19(21)25/h5-8,11-13H,9-10,14H2,1-4H3,(H,26,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50172416 (CHEMBL427540 | N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CC2CC1CN2 Show InChI InChI=1S/C24H23F3N4O3/c1-14-8-22(31-12-16-9-17(31)11-28-16)30-21-7-2-15(10-20(14)21)29-23(32)13-33-18-3-5-19(6-4-18)34-24(25,26)27/h2-8,10,16-17,28H,9,11-13H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50172414 (2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...) Show SMILES CN(C)CCOc1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibitory concentration against dopamine transporter				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50150709 (2-(2,4-Dichloro-phenoxy)-N-[4-methyl-2-(4-methyl-p...) Show SMILES CN1CCN(CC1)c1cc(C)c2cc(NC(=O)COc3ccc(Cl)cc3Cl)ccc2n1 Show InChI InChI=1S/C23H24Cl2N4O2/c1-15-11-22(29-9-7-28(2)8-10-29)27-20-5-4-17(13-18(15)20)26-23(30)14-31-21-6-3-16(24)12-19(21)25/h3-6,11-13H,7-10,14H2,1-2H3,(H,26,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50172424 (CHEMBL198361 | N-(4-Methyl-2-morpholin-4-yl-quinol...) Show SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCOCC1 Show InChI InChI=1S/C23H22F3N3O4/c1-15-12-21(29-8-10-31-11-9-29)28-20-7-2-16(13-19(15)20)27-22(30)14-32-17-3-5-18(6-4-17)33-23(24,25)26/h2-7,12-13H,8-11,14H2,1H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assay				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair

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