Compile Data Set for Download or QSAR

Found 43 hits Enz. Inhib. hit(s) with all data for entry = 50031998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322986 (CHEMBL1210141 | N-(1-((2,6-diethoxy-4'-(trifluorom...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C30H34F3N3O4/c1-4-38-26-15-21(16-27(39-5-2)28(26)22-6-8-25(9-7-22)40-30(31,32)33)19-36-12-10-24(11-13-36)35-29(37)23-14-20(3)17-34-18-23/h6-9,14-18,24H,4-5,10-13,19H2,1-3H3,(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322979 (CHEMBL1210209 | N-(1-((2,6-diethoxy-4'-fluorobiphe...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C29H35FN4O3/c1-4-36-25-16-20(17-26(37-5-2)28(25)21-6-9-23(30)10-7-21)19-34-14-12-24(13-15-34)33-29(35)22-8-11-27(31-3)32-18-22/h6-11,16-18,24H,4-5,12-15,19H2,1-3H3,(H,31,32)(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322988 (CHEMBL1210084 | N-(1-(3,5-diethoxy-4-methylbenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1C Show InChI InChI=1S/C24H33N3O3/c1-5-29-22-12-19(13-23(18(22)4)30-6-2)16-27-9-7-21(8-10-27)26-24(28)20-11-17(3)14-25-15-20/h11-15,21H,5-10,16H2,1-4H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322987 (CHEMBL1210085 | N-(1-(4-chloro-3,5-diethoxybenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1Cl Show InChI InChI=1S/C23H30ClN3O3/c1-4-29-20-11-17(12-21(22(20)24)30-5-2)15-27-8-6-19(7-9-27)26-23(28)18-10-16(3)13-25-14-18/h10-14,19H,4-9,15H2,1-3H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322981 (CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C29H34FN3O3/c1-4-35-26-15-21(16-27(36-5-2)28(26)22-6-8-24(30)9-7-22)19-33-12-10-25(11-13-33)32-29(34)23-14-20(3)17-31-18-23/h6-9,14-18,25H,4-5,10-13,19H2,1-3H3,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322992 (CHEMBL1210030 | N-(1-((2-ethoxy-4'-fluorobiphenyl-...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1-c1ccc(F)cc1 Show InChI InChI=1S/C27H30FN3O2/c1-3-33-26-15-20(4-9-25(26)21-5-7-23(28)8-6-21)18-31-12-10-24(11-13-31)30-27(32)22-14-19(2)16-29-17-22/h4-9,14-17,24H,3,10-13,18H2,1-2H3,(H,30,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322980 (CHEMBL1210208 | N-(1-((2,6-diethoxybiphenyl-4-yl)m...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccccc1 Show InChI InChI=1S/C29H35N3O3/c1-4-34-26-16-22(17-27(35-5-2)28(26)23-9-7-6-8-10-23)20-32-13-11-25(12-14-32)31-29(33)24-15-21(3)18-30-19-24/h6-10,15-19,25H,4-5,11-14,20H2,1-3H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322984 (CHEMBL1210143 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC(C)C)nc2)cc(OCC)c1F Show InChI InChI=1S/C25H35FN4O3/c1-5-32-21-13-18(14-22(24(21)26)33-6-2)16-30-11-9-20(10-12-30)29-25(31)19-7-8-23(27-15-19)28-17(3)4/h7-8,13-15,17,20H,5-6,9-12,16H2,1-4H3,(H,27,28)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322978 (6-amino-N-(1-((2-(benzyloxy)-6-ethoxy-4'-fluorobip...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCc2ccccc2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN4O3/c1-2-40-29-18-24(21-38-16-14-28(15-17-38)37-33(39)26-10-13-31(35)36-20-26)19-30(41-22-23-6-4-3-5-7-23)32(29)25-8-11-27(34)12-9-25/h3-13,18-20,28H,2,14-17,21-22H2,1H3,(H2,35,36)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322983 (CHEMBL1210144 | N-(1-((2,6-diethoxybiphenyl-4-yl)m...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1-c1ccccc1 Show InChI InChI=1S/C29H36N4O3/c1-4-35-25-17-21(18-26(36-5-2)28(25)22-9-7-6-8-10-22)20-33-15-13-24(14-16-33)32-29(34)23-11-12-27(30-3)31-19-23/h6-12,17-19,24H,4-5,13-16,20H2,1-3H3,(H,30,31)(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322985 (6-amino-N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-yl...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C28H33FN4O3/c1-3-35-24-15-19(16-25(36-4-2)27(24)20-5-8-22(29)9-6-20)18-33-13-11-23(12-14-33)32-28(34)21-7-10-26(30)31-17-21/h5-10,15-17,23H,3-4,11-14,18H2,1-2H3,(H2,30,31)(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322982 (6-chloro-N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-y...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(Cl)nc2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C28H31ClFN3O3/c1-3-35-24-15-19(16-25(36-4-2)27(24)20-5-8-22(30)9-6-20)18-33-13-11-23(12-14-33)32-28(34)21-7-10-26(29)31-17-21/h5-10,15-17,23H,3-4,11-14,18H2,1-2H3,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322971 (CHEMBL1210375 | rac-N-(1-((2,6-diethoxy-4'-fluorob...) Show SMILES CCOc1cc(CN2CCCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C30H36FN3O3/c1-4-36-27-16-22(17-28(37-5-2)29(27)23-8-10-25(31)11-9-23)20-34-13-6-7-26(12-14-34)33-30(35)24-15-21(3)18-32-19-24/h8-11,15-19,26H,4-7,12-14,20H2,1-3H3,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322989 (CHEMBL1210083 | N-(1-(3,5-diethoxy-4-(1H-imidazol-...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-n1ccnc1 Show InChI InChI=1S/C26H33N5O3/c1-4-33-23-13-20(14-24(34-5-2)25(23)31-11-8-27-18-31)17-30-9-6-22(7-10-30)29-26(32)21-12-19(3)15-28-16-21/h8,11-16,18,22H,4-7,9-10,17H2,1-3H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322991 (CHEMBL1210031 | N-(1-((2-ethoxy-4'-(trifluoromethy...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H30F3N3O2/c1-3-36-26-15-20(4-9-25(26)21-5-7-23(8-6-21)28(29,30)31)18-34-12-10-24(11-13-34)33-27(35)22-14-19(2)16-32-17-22/h4-9,14-17,24H,3,10-13,18H2,1-2H3,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227129 (CHEMBL241329 | N-(1-(4-chloro-3-ethoxybenzyl)piper...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1Cl Show InChI InChI=1S/C21H26ClN3O2/c1-3-27-20-11-16(4-5-19(20)22)14-25-8-6-18(7-9-25)24-21(26)17-10-15(2)12-23-13-17/h4-5,10-13,18H,3,6-9,14H2,1-2H3,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322976 ((R)-N-(1-(4-chloro-3-ethoxybenzyl)azepan-4-yl)-5-m...) Show SMILES CCOc1cc(CN2CCC[C@H](CC2)NC(=O)c2cncc(C)c2)ccc1Cl |r| Show InChI InChI=1S/C22H28ClN3O2/c1-3-28-21-12-17(6-7-20(21)23)15-26-9-4-5-19(8-10-26)25-22(27)18-11-16(2)13-24-14-18/h6-7,11-14,19H,3-5,8-10,15H2,1-2H3,(H,25,27)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322977 (CHEMBL1210268 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1F Show InChI InChI=1S/C23H31FN4O3/c1-4-30-19-12-16(13-20(22(19)24)31-5-2)15-28-10-8-18(9-11-28)27-23(29)17-6-7-21(25-3)26-14-17/h6-7,12-14,18H,4-5,8-11,15H2,1-3H3,(H,25,26)(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322993 (6-amino-N-(1-(3-ethoxy-4-methylbenzyl)piperidin-4-...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)ccc1C Show InChI InChI=1S/C21H28N4O2/c1-3-27-19-12-16(5-4-15(19)2)14-25-10-8-18(9-11-25)24-21(26)17-6-7-20(22)23-13-17/h4-7,12-13,18H,3,8-11,14H2,1-2H3,(H2,22,23)(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322994 (CHEMBL1210028 | N-(1-(3-ethoxy-4-methylbenzyl)pipe...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1C Show InChI InChI=1S/C22H29N3O2/c1-4-27-21-12-18(6-5-17(21)3)15-25-9-7-20(8-10-25)24-22(26)19-11-16(2)13-23-14-19/h5-6,11-14,20H,4,7-10,15H2,1-3H3,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322972 ((R)-N-(1-(3-ethoxy-4-methylbenzyl)azepan-4-yl)-5-m...) Show SMILES CCOc1cc(CN2CCC[C@H](CC2)NC(=O)c2cncc(C)c2)ccc1C |r| Show InChI InChI=1S/C23H31N3O2/c1-4-28-22-13-19(8-7-18(22)3)16-26-10-5-6-21(9-11-26)25-23(27)20-12-17(2)14-24-15-20/h7-8,12-15,21H,4-6,9-11,16H2,1-3H3,(H,25,27)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322974 ((R)-N-(1-(3,5-diethoxy-4-fluorobenzyl)azepan-4-yl)...) Show SMILES CCOc1cc(CN2CCC[C@H](CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1F |r| Show InChI InChI=1S/C24H32FN3O3/c1-4-30-21-12-18(13-22(23(21)25)31-5-2)16-28-9-6-7-20(8-10-28)27-24(29)19-11-17(3)14-26-15-19/h11-15,20H,4-10,16H2,1-3H3,(H,27,29)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322973 (CHEMBL1210373 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1F Show InChI InChI=1S/C23H30FN3O3/c1-4-29-20-11-17(12-21(22(20)24)30-5-2)15-27-8-6-19(7-9-27)26-23(28)18-10-16(3)13-25-14-18/h10-14,19H,4-9,15H2,1-3H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322990 (CHEMBL1210082 | rac-6-amino-N-(1-(3-ethoxy-4,5-dif...) Show SMILES CCOc1cc(CN2CCCC(CC2)NC(=O)c2ccc(N)nc2)cc(F)c1F Show InChI InChI=1S/C21H26F2N4O2/c1-2-29-18-11-14(10-17(22)20(18)23)13-27-8-3-4-16(7-9-27)26-21(28)15-5-6-19(24)25-12-15/h5-6,10-12,16H,2-4,7-9,13H2,1H3,(H2,24,25)(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	436	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322975 ((S)-N-(1-(4-chloro-3-ethoxybenzyl)azepan-4-yl)-5-m...) Show SMILES CCOc1cc(CN2CCC[C@@H](CC2)NC(=O)c2cncc(C)c2)ccc1Cl |r| Show InChI InChI=1S/C22H28ClN3O2/c1-3-28-21-12-17(6-7-20(21)23)15-26-9-4-5-19(8-10-26)25-22(27)18-11-16(2)13-24-14-18/h6-7,11-14,19H,3-5,8-10,15H2,1-2H3,(H,25,27)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	637	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322970 (CHEMBL1210376 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CC(C2)NC(=O)c2cncc(C)c2)cc(OCC)c1F Show InChI InChI=1S/C21H26FN3O3/c1-4-27-18-7-15(8-19(20(18)22)28-5-2)11-25-12-17(13-25)24-21(26)16-6-14(3)9-23-10-16/h6-10,17H,4-5,11-13H2,1-3H3,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322990 (CHEMBL1210082 | rac-6-amino-N-(1-(3-ethoxy-4,5-dif...) Show SMILES CCOc1cc(CN2CCCC(CC2)NC(=O)c2ccc(N)nc2)cc(F)c1F Show InChI InChI=1S/C21H26F2N4O2/c1-2-29-18-11-14(10-17(22)20(18)23)13-27-8-3-4-16(7-9-27)26-21(28)15-5-6-19(24)25-12-15/h5-6,10-12,16H,2-4,7-9,13H2,1H3,(H2,24,25)(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322989 (CHEMBL1210083 | N-(1-(3,5-diethoxy-4-(1H-imidazol-...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-n1ccnc1 Show InChI InChI=1S/C26H33N5O3/c1-4-33-23-13-20(14-24(34-5-2)25(23)31-11-8-27-18-31)17-30-9-6-22(7-10-30)29-26(32)21-12-19(3)15-28-16-21/h8,11-16,18,22H,4-7,9-10,17H2,1-3H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322987 (CHEMBL1210085 | N-(1-(4-chloro-3,5-diethoxybenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1Cl Show InChI InChI=1S/C23H30ClN3O3/c1-4-29-20-11-17(12-21(22(20)24)30-5-2)15-27-8-6-19(7-9-27)26-23(28)18-10-16(3)13-25-14-18/h10-14,19H,4-9,15H2,1-3H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322986 (CHEMBL1210141 | N-(1-((2,6-diethoxy-4'-(trifluorom...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C30H34F3N3O4/c1-4-38-26-15-21(16-27(39-5-2)28(26)22-6-8-25(9-7-22)40-30(31,32)33)19-36-12-10-24(11-13-36)35-29(37)23-14-20(3)17-34-18-23/h6-9,14-18,24H,4-5,10-13,19H2,1-3H3,(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322985 (6-amino-N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-yl...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C28H33FN4O3/c1-3-35-24-15-19(16-25(36-4-2)27(24)20-5-8-22(29)9-6-20)18-33-13-11-23(12-14-33)32-28(34)21-7-10-26(30)31-17-21/h5-10,15-17,23H,3-4,11-14,18H2,1-2H3,(H2,30,31)(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322971 (CHEMBL1210375 | rac-N-(1-((2,6-diethoxy-4'-fluorob...) Show SMILES CCOc1cc(CN2CCCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C30H36FN3O3/c1-4-36-27-16-22(17-28(37-5-2)29(27)23-8-10-25(31)11-9-23)20-34-13-6-7-26(12-14-34)33-30(35)24-15-21(3)18-32-19-24/h8-11,15-19,26H,4-7,12-14,20H2,1-3H3,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322983 (CHEMBL1210144 | N-(1-((2,6-diethoxybiphenyl-4-yl)m...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1-c1ccccc1 Show InChI InChI=1S/C29H36N4O3/c1-4-35-25-17-21(18-26(36-5-2)28(25)22-9-7-6-8-10-22)20-33-15-13-24(14-16-33)32-29(34)23-11-12-27(30-3)31-19-23/h6-12,17-19,24H,4-5,13-16,20H2,1-3H3,(H,30,31)(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322982 (6-chloro-N-(1-((2,6-diethoxy-4'-fluorobiphenyl-4-y...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(Cl)nc2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C28H31ClFN3O3/c1-3-35-24-15-19(16-25(36-4-2)27(24)20-5-8-22(30)9-6-20)18-33-13-11-23(12-14-33)32-28(34)21-7-10-26(29)31-17-21/h5-10,15-17,23H,3-4,11-14,18H2,1-2H3,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322981 (CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C29H34FN3O3/c1-4-35-26-15-21(16-27(36-5-2)28(26)22-6-8-24(30)9-7-22)19-33-12-10-25(11-13-33)32-29(34)23-14-20(3)17-31-18-23/h6-9,14-18,25H,4-5,10-13,19H2,1-3H3,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322980 (CHEMBL1210208 | N-(1-((2,6-diethoxybiphenyl-4-yl)m...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1-c1ccccc1 Show InChI InChI=1S/C29H35N3O3/c1-4-34-26-16-22(17-27(35-5-2)28(26)23-9-7-6-8-10-23)20-32-13-11-25(12-14-32)31-29(33)24-15-21(3)18-30-19-24/h6-10,15-19,25H,4-5,11-14,20H2,1-3H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322979 (CHEMBL1210209 | N-(1-((2,6-diethoxy-4'-fluorobiphe...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1-c1ccc(F)cc1 Show InChI InChI=1S/C29H35FN4O3/c1-4-36-25-16-20(17-26(37-5-2)28(25)21-6-9-23(30)10-7-21)19-34-14-12-24(13-15-34)33-29(35)22-8-11-27(31-3)32-18-22/h6-11,16-18,24H,4-5,12-15,19H2,1-3H3,(H,31,32)(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322978 (6-amino-N-(1-((2-(benzyloxy)-6-ethoxy-4'-fluorobip...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)cc(OCc2ccccc2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C33H35FN4O3/c1-2-40-29-18-24(21-38-16-14-28(15-17-38)37-33(39)26-10-13-31(35)36-20-26)19-30(41-22-23-6-4-3-5-7-23)32(29)25-8-11-27(34)12-9-25/h3-13,18-20,28H,2,14-17,21-22H2,1H3,(H2,35,36)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322977 (CHEMBL1210268 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC)nc2)cc(OCC)c1F Show InChI InChI=1S/C23H31FN4O3/c1-4-30-19-12-16(13-20(22(19)24)31-5-2)15-28-10-8-18(9-11-28)27-23(29)17-6-7-21(25-3)26-14-17/h6-7,12-14,18H,4-5,8-11,15H2,1-3H3,(H,25,26)(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322973 (CHEMBL1210373 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)cc(OCC)c1F Show InChI InChI=1S/C23H30FN3O3/c1-4-29-20-11-17(12-21(22(20)24)30-5-2)15-27-8-6-19(7-9-27)26-23(28)18-10-16(3)13-25-14-18/h10-14,19H,4-9,15H2,1-3H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322992 (CHEMBL1210030 | N-(1-((2-ethoxy-4'-fluorobiphenyl-...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2cncc(C)c2)ccc1-c1ccc(F)cc1 Show InChI InChI=1S/C27H30FN3O2/c1-3-33-26-15-20(4-9-25(26)21-5-7-23(28)8-6-21)18-31-12-10-24(11-13-31)30-27(32)22-14-19(2)16-29-17-22/h4-9,14-17,24H,3,10-13,18H2,1-2H3,(H,30,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322993 (6-amino-N-(1-(3-ethoxy-4-methylbenzyl)piperidin-4-...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(N)nc2)ccc1C Show InChI InChI=1S/C21H28N4O2/c1-3-27-19-12-16(5-4-15(19)2)14-25-10-8-18(9-11-25)24-21(26)17-6-7-20(22)23-13-17/h4-7,12-13,18H,3,8-11,14H2,1-2H3,(H2,22,23)(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50322984 (CHEMBL1210143 | N-(1-(3,5-diethoxy-4-fluorobenzyl)...) Show SMILES CCOc1cc(CN2CCC(CC2)NC(=O)c2ccc(NC(C)C)nc2)cc(OCC)c1F Show InChI InChI=1S/C25H35FN4O3/c1-5-32-21-13-18(14-22(24(21)26)33-6-2)16-30-11-9-20(10-12-30)29-25(31)19-7-8-23(27-15-19)28-17(3)4/h7-8,13-15,17,20H,5-6,9-12,16H2,1-4H3,(H,27,28)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assay				Bioorg Med Chem Lett 20: 4521-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.026 BindingDB Entry DOI: 10.7270/Q2J103BN
					More data for this Ligand-Target Pair