Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 50039587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380385 (CHEMBL2018447) Show SMILES NC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C22H24N4O3/c23-21(27)10-12-25-11-9-20-18(14-25)17-3-1-2-4-19(17)26(20)13-15-5-7-16(8-6-15)22(28)24-29/h1-8,29H,9-14H2,(H2,23,27)(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.459	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380391 (CHEMBL2018446) Show SMILES ONC(=O)c1ccc(Cn2c3CCN(Cc4ccncc4)Cc3c3ccccc23)cc1 Show InChI InChI=1S/C25H24N4O2/c30-25(27-31)20-7-5-18(6-8-20)16-29-23-4-2-1-3-21(23)22-17-28(14-11-24(22)29)15-19-9-12-26-13-10-19/h1-10,12-13,31H,11,14-17H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.582	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380400 (CHEMBL2018301) Show SMILES CN1CCc2c(C1)c1cc(Br)ccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H20BrN3O2/c1-23-9-8-19-17(12-23)16-10-15(21)6-7-18(16)24(19)11-13-2-4-14(5-3-13)20(25)22-26/h2-7,10,26H,8-9,11-12H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.704	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380390 (CHEMBL2018448) Show SMILES NC(=O)CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H22N4O3/c22-20(26)13-24-10-9-19-17(12-24)16-3-1-2-4-18(16)25(19)11-14-5-7-15(8-6-14)21(27)23-28/h1-8,28H,9-13H2,(H2,22,26)(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.799	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380386 (CHEMBL2018452) Show SMILES ONC(=O)c1ccc(Cn2c3CN(Cc4ccccc4)CCc3c3ccccc23)cc1 Show InChI InChI=1S/C26H25N3O2/c30-26(27-31)21-12-10-20(11-13-21)17-29-24-9-5-4-8-22(24)23-14-15-28(18-25(23)29)16-19-6-2-1-3-7-19/h1-13,31H,14-18H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.872	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380384 (CHEMBL2018442) Show SMILES ONC(=O)c1ccc(Cn2c3CCN(CC=C)Cc3c3ccccc23)cc1 Show InChI InChI=1S/C22H23N3O2/c1-2-12-24-13-11-21-19(15-24)18-5-3-4-6-20(18)25(21)14-16-7-9-17(10-8-16)22(26)23-27/h2-10,27H,1,11-15H2,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.972	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380401 (CHEMBL2018300) Show SMILES CN1CCc2c(C1)c1cc(Cl)ccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H20ClN3O2/c1-23-9-8-19-17(12-23)16-10-15(21)6-7-18(16)24(19)11-13-2-4-14(5-3-13)20(25)22-26/h2-7,10,26H,8-9,11-12H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380387 (CHEMBL2018451) Show SMILES CN1CCc2c(C1)n(Cc1ccc(cc1)C(=O)NO)c1ccccc21 Show InChI InChI=1S/C20H21N3O2/c1-22-11-10-17-16-4-2-3-5-18(16)23(19(17)13-22)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380394 (CHEMBL2018443) Show SMILES ONC(=O)c1ccc(Cn2c3CCN(Cc4ccccc4)Cc3c3ccccc23)cc1 Show InChI InChI=1S/C26H25N3O2/c30-26(27-31)21-12-10-20(11-13-21)17-29-24-9-5-4-8-22(24)23-18-28(15-14-25(23)29)16-19-6-2-1-3-7-19/h1-13,31H,14-18H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380398 (CHEMBL2018303) Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C24H27N3O4/c1-24(2,3)31-23(29)26-13-12-21-19(15-26)18-6-4-5-7-20(18)27(21)14-16-8-10-17(11-9-16)22(28)25-30/h4-11,30H,12-15H2,1-3H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380388 (CHEMBL2018450) Show SMILES ONC(=O)c1ccc(Cn2c3CNCCc3c3ccccc23)cc1 Show InChI InChI=1S/C19H19N3O2/c23-19(21-24)14-7-5-13(6-8-14)12-22-17-4-2-1-3-15(17)16-9-10-20-11-18(16)22/h1-8,20,24H,9-12H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380393 (CHEMBL2018444) Show SMILES COc1cccc(CN2CCc3c(C2)c2ccccc2n3Cc2ccc(cc2)C(=O)NO)c1 Show InChI InChI=1S/C27H27N3O3/c1-33-22-6-4-5-20(15-22)16-29-14-13-26-24(18-29)23-7-2-3-8-25(23)30(26)17-19-9-11-21(12-10-19)27(31)28-32/h2-12,15,32H,13-14,16-18H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.96	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380396 (CHEMBL2018305) Show SMILES CCN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-2-23-12-11-20-18(14-23)17-5-3-4-6-19(17)24(20)13-15-7-9-16(10-8-15)21(25)22-26/h3-10,26H,2,11-14H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380392 (CHEMBL2018445) Show SMILES COc1ccc(CN2CCc3c(C2)c2ccccc2n3Cc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C27H27N3O3/c1-33-22-12-8-19(9-13-22)16-29-15-14-26-24(18-29)23-4-2-3-5-25(23)30(26)17-20-6-10-21(11-7-20)27(31)28-32/h2-13,32H,14-18H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.05	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380402 (CHEMBL2018299) Show SMILES COc1ccc2n(Cc3ccc(cc3)C(=O)NO)c3CCN(C)Cc3c2c1 Show InChI InChI=1S/C21H23N3O3/c1-23-10-9-20-18(13-23)17-11-16(27-2)7-8-19(17)24(20)12-14-3-5-15(6-4-14)21(25)22-26/h3-8,11,26H,9-10,12-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380389 (CHEMBL2018449) Show SMILES NC(=O)CCCN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C23H26N4O3/c24-22(28)6-3-12-26-13-11-21-19(15-26)18-4-1-2-5-20(18)27(21)14-16-7-9-17(10-8-16)23(29)25-30/h1-2,4-5,7-10,30H,3,6,11-15H2,(H2,24,28)(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.06	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380405 (CHEMBL2018296) Show SMILES CN1CCc2c(C1)c1cc(C)ccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-3-8-19-17(11-14)18-13-23(2)10-9-20(18)24(19)12-15-4-6-16(7-5-15)21(25)22-26/h3-8,11,26H,9-10,12-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380397 (CHEMBL2018304) Show SMILES ONC(=O)c1ccc(Cn2c3CCNCc3c3ccccc23)cc1 Show InChI InChI=1S/C19H19N3O2/c23-19(21-24)14-7-5-13(6-8-14)12-22-17-4-2-1-3-15(17)16-11-20-10-9-18(16)22/h1-8,20,24H,9-12H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.56	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380395 (CHEMBL2018441) Show SMILES CC(C)N1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C22H25N3O2/c1-15(2)24-12-11-21-19(14-24)18-5-3-4-6-20(18)25(21)13-16-7-9-17(10-8-16)22(26)23-27/h3-10,15,27H,11-14H2,1-2H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.96	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380406 (CHEMBL2018295) Show SMILES CN1CCc2c(C1)c1ccc(C)cc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-3-8-17-18-13-23(2)10-9-19(18)24(20(17)11-14)12-15-4-6-16(7-5-15)21(25)22-26/h3-8,11,26H,9-10,12-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380399 (CHEMBL2018302 | Tubastatin A | US10227295, Compoun...) Show SMILES CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380403 (CHEMBL2018298) Show SMILES CN1CCc2c(C1)c1cc(ccc1n2Cc1ccc(cc1)C(=O)NO)C(C)(C)C Show InChI InChI=1S/C24H29N3O2/c1-24(2,3)18-9-10-21-19(13-18)20-15-26(4)12-11-22(20)27(21)14-16-5-7-17(8-6-16)23(28)25-29/h5-10,13,29H,11-12,14-15H2,1-4H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380407 (CHEMBL2018294) Show SMILES CN1CCc2c(C1)c1cccc(C)c1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-4-3-5-17-18-13-23(2)11-10-19(18)24(20(14)17)12-15-6-8-16(9-7-15)21(25)22-26/h3-9,26H,10-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380404 (CHEMBL2018297) Show SMILES CN1CCc2c(C1)c1c(C)cc(C)cc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C22H25N3O2/c1-14-10-15(2)21-18-13-24(3)9-8-19(18)25(20(21)11-14)12-16-4-6-17(7-5-16)22(26)23-27/h4-7,10-11,27H,8-9,12-13H2,1-3H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38.4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380400 (CHEMBL2018301) Show SMILES CN1CCc2c(C1)c1cc(Br)ccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H20BrN3O2/c1-23-9-8-19-17(12-23)16-10-15(21)6-7-18(16)24(19)11-13-2-4-14(5-3-13)20(25)22-26/h2-7,10,26H,8-9,11-12H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380401 (CHEMBL2018300) Show SMILES CN1CCc2c(C1)c1cc(Cl)ccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H20ClN3O2/c1-23-9-8-19-17(12-23)16-10-15(21)6-7-18(16)24(19)11-13-2-4-14(5-3-13)20(25)22-26/h2-7,10,26H,8-9,11-12H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380385 (CHEMBL2018447) Show SMILES NC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C22H24N4O3/c23-21(27)10-12-25-11-9-20-18(14-25)17-3-1-2-4-19(17)26(20)13-15-5-7-16(8-6-15)22(28)24-29/h1-8,29H,9-14H2,(H2,23,27)(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380402 (CHEMBL2018299) Show SMILES COc1ccc2n(Cc3ccc(cc3)C(=O)NO)c3CCN(C)Cc3c2c1 Show InChI InChI=1S/C21H23N3O3/c1-23-10-9-20-18(13-23)17-11-16(27-2)7-8-19(17)24(20)12-14-3-5-15(6-4-14)21(25)22-26/h3-8,11,26H,9-10,12-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380405 (CHEMBL2018296) Show SMILES CN1CCc2c(C1)c1cc(C)ccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-3-8-19-17(11-14)18-13-23(2)10-9-20(18)24(19)12-15-4-6-16(7-5-15)21(25)22-26/h3-8,11,26H,9-10,12-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380391 (CHEMBL2018446) Show SMILES ONC(=O)c1ccc(Cn2c3CCN(Cc4ccncc4)Cc3c3ccccc23)cc1 Show InChI InChI=1S/C25H24N4O2/c30-25(27-31)20-7-5-18(6-8-20)16-29-23-4-2-1-3-21(23)22-17-28(14-11-24(22)29)15-19-9-12-26-13-10-19/h1-10,12-13,31H,11,14-17H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380390 (CHEMBL2018448) Show SMILES NC(=O)CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H22N4O3/c22-20(26)13-24-10-9-19-17(12-24)16-3-1-2-4-18(16)25(19)11-14-5-7-15(8-6-14)21(27)23-28/h1-8,28H,9-13H2,(H2,22,26)(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380406 (CHEMBL2018295) Show SMILES CN1CCc2c(C1)c1ccc(C)cc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-3-8-17-18-13-23(2)10-9-19(18)24(20(17)11-14)12-15-4-6-16(7-5-15)21(25)22-26/h3-8,11,26H,9-10,12-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380386 (CHEMBL2018452) Show SMILES ONC(=O)c1ccc(Cn2c3CN(Cc4ccccc4)CCc3c3ccccc23)cc1 Show InChI InChI=1S/C26H25N3O2/c30-26(27-31)21-12-10-20(11-13-21)17-29-24-9-5-4-8-22(24)23-14-15-28(18-25(23)29)16-19-6-2-1-3-7-19/h1-13,31H,14-18H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380392 (CHEMBL2018445) Show SMILES COc1ccc(CN2CCc3c(C2)c2ccccc2n3Cc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C27H27N3O3/c1-33-22-12-8-19(9-13-22)16-29-15-14-26-24(18-29)23-4-2-3-5-25(23)30(26)17-20-6-10-21(11-7-20)27(31)28-32/h2-13,32H,14-18H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380387 (CHEMBL2018451) Show SMILES CN1CCc2c(C1)n(Cc1ccc(cc1)C(=O)NO)c1ccccc21 Show InChI InChI=1S/C20H21N3O2/c1-22-11-10-17-16-4-2-3-5-18(16)23(19(17)13-22)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380393 (CHEMBL2018444) Show SMILES COc1cccc(CN2CCc3c(C2)c2ccccc2n3Cc2ccc(cc2)C(=O)NO)c1 Show InChI InChI=1S/C27H27N3O3/c1-33-22-6-4-5-20(15-22)16-29-14-13-26-24(18-29)23-7-2-3-8-25(23)30(26)17-19-9-11-21(12-10-19)27(31)28-32/h2-12,15,32H,13-14,16-18H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380384 (CHEMBL2018442) Show SMILES ONC(=O)c1ccc(Cn2c3CCN(CC=C)Cc3c3ccccc23)cc1 Show InChI InChI=1S/C22H23N3O2/c1-2-12-24-13-11-21-19(15-24)18-5-3-4-6-20(18)25(21)14-16-7-9-17(10-8-16)22(26)23-27/h2-10,27H,1,11-15H2,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380389 (CHEMBL2018449) Show SMILES NC(=O)CCCN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C23H26N4O3/c24-22(28)6-3-12-26-13-11-21-19(15-26)18-4-1-2-5-20(18)27(21)14-16-7-9-17(10-8-16)23(29)25-30/h1-2,4-5,7-10,30H,3,6,11-15H2,(H2,24,28)(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380398 (CHEMBL2018303) Show SMILES CC(C)(C)OC(=O)N1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C24H27N3O4/c1-24(2,3)31-23(29)26-13-12-21-19(15-26)18-6-4-5-7-20(18)27(21)14-16-8-10-17(11-9-16)22(28)25-30/h4-11,30H,12-15H2,1-3H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380388 (CHEMBL2018450) Show SMILES ONC(=O)c1ccc(Cn2c3CNCCc3c3ccccc23)cc1 Show InChI InChI=1S/C19H19N3O2/c23-19(21-24)14-7-5-13(6-8-14)12-22-17-4-2-1-3-15(17)16-9-10-20-11-18(16)22/h1-8,20,24H,9-12H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380396 (CHEMBL2018305) Show SMILES CCN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-2-23-12-11-20-18(14-23)17-5-3-4-6-19(17)24(20)13-15-7-9-16(10-8-15)21(25)22-26/h3-10,26H,2,11-14H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380394 (CHEMBL2018443) Show SMILES ONC(=O)c1ccc(Cn2c3CCN(Cc4ccccc4)Cc3c3ccccc23)cc1 Show InChI InChI=1S/C26H25N3O2/c30-26(27-31)21-12-10-20(11-13-21)17-29-24-9-5-4-8-22(24)23-18-28(15-14-25(23)29)16-19-6-2-1-3-7-19/h1-13,31H,14-18H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380404 (CHEMBL2018297) Show SMILES CN1CCc2c(C1)c1c(C)cc(C)cc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C22H25N3O2/c1-14-10-15(2)21-18-13-24(3)9-8-19(18)25(20(21)11-14)12-16-4-6-17(7-5-16)22(26)23-27/h4-7,10-11,27H,8-9,12-13H2,1-3H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380403 (CHEMBL2018298) Show SMILES CN1CCc2c(C1)c1cc(ccc1n2Cc1ccc(cc1)C(=O)NO)C(C)(C)C Show InChI InChI=1S/C24H29N3O2/c1-24(2,3)18-9-10-21-19(13-18)20-15-26(4)12-11-22(20)27(21)14-16-5-7-17(8-6-16)23(28)25-29/h5-10,13,29H,11-12,14-15H2,1-4H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380395 (CHEMBL2018441) Show SMILES CC(C)N1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C22H25N3O2/c1-15(2)24-12-11-21-19(14-24)18-5-3-4-6-20(18)25(21)13-16-7-9-17(10-8-16)22(26)23-27/h3-10,15,27H,11-14H2,1-2H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380399 (CHEMBL2018302 | Tubastatin A | US10227295, Compoun...) Show SMILES CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380397 (CHEMBL2018304) Show SMILES ONC(=O)c1ccc(Cn2c3CCNCc3c3ccccc23)cc1 Show InChI InChI=1S/C19H19N3O2/c23-19(21-24)14-7-5-13(6-8-14)12-22-17-4-2-1-3-15(17)16-11-20-10-9-18(16)22/h1-8,20,24H,9-12H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50380407 (CHEMBL2018294) Show SMILES CN1CCc2c(C1)c1cccc(C)c1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H23N3O2/c1-14-4-3-5-17-18-13-23(2)11-10-19(18)24(20(14)17)12-15-6-8-16(9-7-15)21(25)22-26/h3-9,26H,10-13H2,1-2H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using RHKKAc peptide as substrate incubated for 5 to mins prior to substrate addition measured after 2 hrs				J Med Chem 55: 639-51 (2012) Article DOI: 10.1021/jm200773h BindingDB Entry DOI: 10.7270/Q2CJ8FG7
					More data for this Ligand-Target Pair