Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50041824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416380 (CHEMBL1210561) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1cccc(c1Cl)C(F)(F)F Show InChI InChI=1S/C15H15ClF3N3O/c1-8-11(9(2)22-21-8)6-13(23)20-7-10-4-3-5-12(14(10)16)15(17,18)19/h3-5H,6-7H2,1-2H3,(H,20,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416375 (CHEMBL1210623) Show SMILES Cc1noc(C)c1CC(=O)NCc1cccc(c1Cl)C(F)(F)F Show InChI InChI=1S/C15H14ClF3N2O2/c1-8-11(9(2)23-21-8)6-13(22)20-7-10-4-3-5-12(14(10)16)15(17,18)19/h3-5H,6-7H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416378 (CHEMBL1210563) Show SMILES Cc1cnn(C)c1CC(=O)NCc1cccc(c1Cl)C(F)(F)F Show InChI InChI=1S/C15H15ClF3N3O/c1-9-7-21-22(2)12(9)6-13(23)20-8-10-4-3-5-11(14(10)16)15(17,18)19/h3-5,7H,6,8H2,1-2H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416383 (CHEMBL1210558) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C14H15Cl2N3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416395 (CHEMBL1210369) Show SMILES CCc1n[nH]c(CC)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C17H21ClFN3O/c1-3-15-13(16(4-2)22-21-15)7-8-17(23)20-10-11-5-6-12(19)9-14(11)18/h5-6,9H,3-4,7-8,10H2,1-2H3,(H,20,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416379 (CHEMBL1210562) Show SMILES Cc1cnn(C)c1CC(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C14H15Cl2N3O/c1-9-7-18-19(2)13(9)6-14(20)17-8-10-3-4-11(15)5-12(10)16/h3-5,7H,6,8H2,1-2H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416377 (CHEMBL1210621) Show SMILES Cn1ncc(F)c1CC(=O)NCc1cccc(c1Cl)C(F)(F)F Show InChI InChI=1S/C14H12ClF4N3O/c1-22-11(10(16)7-21-22)5-12(23)20-6-8-3-2-4-9(13(8)15)14(17,18)19/h2-4,7H,5-6H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416390 (CHEMBL1210439) Show SMILES Cc1[nH]nc(c1CCC(=O)NCc1ccc(F)cc1Cl)C(F)(F)F Show InChI InChI=1S/C15H14ClF4N3O/c1-8-11(14(23-22-8)15(18,19)20)4-5-13(24)21-7-9-2-3-10(17)6-12(9)16/h2-3,6H,4-5,7H2,1H3,(H,21,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416376 (CHEMBL1210622) Show SMILES Cc1noc(C)c1CC(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C14H14Cl2N2O2/c1-8-12(9(2)20-18-8)6-14(19)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415882 (CHEMBL1094106) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C14H15ClFN3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(16)5-13(10)15/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416382 (CHEMBL1210559) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1C(F)(F)F Show InChI InChI=1S/C15H15F4N3O/c1-8-12(9(2)22-21-8)6-14(23)20-7-10-3-4-11(16)5-13(10)15(17,18)19/h3-5H,6-7H2,1-2H3,(H,20,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416386 (CHEMBL1210500) Show SMILES Cc1noc(C)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C15H16ClFN2O2/c1-9-13(10(2)21-19-9)5-6-15(20)18-8-11-3-4-12(17)7-14(11)16/h3-4,7H,5-6,8H2,1-2H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416381 (CHEMBL1210560) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C15H15ClF3N3O/c1-8-11(9(2)22-21-8)6-14(23)20-7-10-3-4-13(16)12(5-10)15(17,18)19/h3-5H,6-7H2,1-2H3,(H,20,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50416383 (CHEMBL1210558) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C14H15Cl2N3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416393 (CHEMBL1210436) Show SMILES CC(C)Cc1n[nH]c(C)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C18H23ClFN3O/c1-11(2)8-17-15(12(3)22-23-17)6-7-18(24)21-10-13-4-5-14(20)9-16(13)19/h4-5,9,11H,6-8,10H2,1-3H3,(H,21,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416394 (CHEMBL1210435) Show SMILES CC(C)c1n[nH]c(C(C)C)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C19H25ClFN3O/c1-11(2)18-15(19(12(3)4)24-23-18)7-8-17(25)22-10-13-5-6-14(21)9-16(13)20/h5-6,9,11-12H,7-8,10H2,1-4H3,(H,22,25)(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416388 (CHEMBL1210498) Show SMILES Cc1cnn(C)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C15H17ClFN3O/c1-10-8-19-20(2)14(10)5-6-15(21)18-9-11-3-4-12(17)7-13(11)16/h3-4,7-8H,5-6,9H2,1-2H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416385 (CHEMBL1210503) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C14H16ClN3O/c1-9-13(10(2)18-17-9)7-14(19)16-8-11-4-3-5-12(15)6-11/h3-6H,7-8H2,1-2H3,(H,16,19)(H,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50415882 (CHEMBL1094106) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C14H15ClFN3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(16)5-13(10)15/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416374 (CHEMBL1210501) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1F Show InChI InChI=1S/C14H15F2N3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416392 (CHEMBL1210437) Show SMILES Cc1[nH]nc(c1CCC(=O)NCc1ccc(F)cc1Cl)C(C)(C)C Show InChI InChI=1S/C18H23ClFN3O/c1-11-14(17(23-22-11)18(2,3)4)7-8-16(24)21-10-12-5-6-13(20)9-15(12)19/h5-6,9H,7-8,10H2,1-4H3,(H,21,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416373 (CHEMBL1210502) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C14H16ClN3O/c1-9-12(10(2)18-17-9)7-14(19)16-8-11-5-3-4-6-13(11)15/h3-6H,7-8H2,1-2H3,(H,16,19)(H,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416387 (CHEMBL1210499) Show SMILES Cc1cc(CCC(=O)NCc2ccc(F)cc2Cl)n(C)n1 Show InChI InChI=1S/C15H17ClFN3O/c1-10-7-13(20(2)19-10)5-6-15(21)18-9-11-3-4-12(17)8-14(11)16/h3-4,7-8H,5-6,9H2,1-2H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416389 (CHEMBL1210440) Show SMILES Cc1cn[nH]c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C14H15ClFN3O/c1-9-7-18-19-13(9)4-5-14(20)17-8-10-2-3-11(16)6-12(10)15/h2-3,6-7H,4-5,8H2,1H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416384 (CHEMBL1210504) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C14H16ClN3O/c1-9-13(10(2)18-17-9)7-14(19)16-8-11-3-5-12(15)6-4-11/h3-6H,7-8H2,1-2H3,(H,16,19)(H,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416391 (CHEMBL1210438) Show SMILES Cc1[nH]nc(c1CCC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-17(20(25-24-13)14-5-3-2-4-6-14)9-10-19(26)23-12-15-7-8-16(22)11-18(15)21/h2-8,11H,9-10,12H2,1H3,(H,23,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair