Compile Data Set for Download or QSAR

Found 94 hits Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 10'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607682 (CHEMBL5220685) Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607676 (CHEMBL5218698) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607678 (CHEMBL5218878) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607681 (CHEMBL5218552) Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607679 (CHEMBL5218615) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607682 (CHEMBL5220685) Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607686 (CHEMBL5219830) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607683 (CHEMBL5219579) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607676 (CHEMBL5218698) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607680 (CHEMBL5218702) Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607685 (CHEMBL5220647) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607678 (CHEMBL5218878) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607686 (CHEMBL5219830) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607684 (CHEMBL5219443) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607673 (CHEMBL5220895) Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3CC(C2)O3)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607674 (CHEMBL5220347) Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3(COC3)C2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607685 (CHEMBL5220647) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607672 (CHEMBL5220723) Show SMILES Cn1cc(Cc2ccccc2OCCN2CCOCC2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607679 (CHEMBL5218615) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607675 (CHEMBL5219922) Show SMILES Cn1cc(Cc2ccccc2OCCN2CCNC(=O)C2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607680 (CHEMBL5218702) Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607681 (CHEMBL5218552) Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607667 (CHEMBL5219530) Show SMILES COC(=O)c1ccccc1Cc1cn(C)nc1-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607684 (CHEMBL5219443) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607677 (CHEMBL5220632) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577248 (CHEMBL4878379) Show SMILES COC(=O)c1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607683 (CHEMBL5219579) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607677 (CHEMBL5220632) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607660 (CHEMBL5221008) Show SMILES Cn1cc(Cc2ccccc2Cl)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607666 (CHEMBL5220075) Show SMILES COc1ccccc1Cc1cn(C)nc1-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607671 (CHEMBL5221093) Show SMILES Cn1cc(Cc2ccccc2Oc2ccccc2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577243 (CHEMBL4868801) Show SMILES Cc1c(Cc2cccc(Cl)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607662 (CHEMBL5219193) Show SMILES Nc1nc(Cl)cc(n1)-c1nn2ccccc2c1Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577244 (CHEMBL4864668) Show SMILES Cc1c(Cc2cccc(F)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577236 (CHEMBL4857305) Show SMILES Cn1cc(Cc2ccccc2F)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577232 (CHEMBL4849033) Show SMILES Cn1cc(Cc2cccs2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577232 (CHEMBL4849033) Show SMILES Cn1cc(Cc2cccs2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577233 (CHEMBL4874288) Show SMILES Cn1cc(Cc2cccc(F)c2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577245 (CHEMBL4866319) Show SMILES Cc1c(Cn2cccn2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577234 (CHEMBL4864843) Show SMILES Cn1cc(Cc2ccc(F)cc2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	342	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577235 (CHEMBL4867202) Show SMILES COc1cccc(Cc2cn(C)nc2-c2cc(Cl)nc(N)n2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577235 (CHEMBL4867202) Show SMILES COc1cccc(Cc2cn(C)nc2-c2cc(Cl)nc(N)n2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607664 (CHEMBL5219159) Show SMILES Cn1cc(Cc2cccc(Cl)c2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577233 (CHEMBL4874288) Show SMILES Cn1cc(Cc2cccc(F)c2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)

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