Found 25 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
Reactome pathway
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PC sid
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| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibitory concentration of compound against CDK2/cyclin A |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
UniProtKB/SwissProt
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antibodypedia
antibodypedia
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
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| Article
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| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of CDK1/cyclin B |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
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| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of cyclin dependent kinase CDK1 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50169895
(3-{5-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(8-13)23-17-22-11-21-16(24-17)12-7-15(10-19-9-12)20-5-2-6-25/h1,3-4,7-11,20,25H,2,5-6H2,(H,21,22,23,24) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of cyclin dependent kinase (CDK1) |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-H/Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
NCI pathway
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PC sid
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| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of CDK7/cyclin H |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
NCI pathway
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KEGG
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PC sid
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| Article
PubMed
| n/a | n/a | 308 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of CDK4/cyclin D1 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50169896
(3-{5-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylamino)-[...)Show InChI InChI=1S/C19H20N6O3/c26-5-1-4-21-15-8-13(10-20-11-15)18-22-12-23-19(25-18)24-14-2-3-16-17(9-14)28-7-6-27-16/h2-3,8-12,21,26H,1,4-7H2,(H,22,23,24,25) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 344 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of cyclin dependent kinase (CDK1) |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
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PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 356 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of CDK6/cyclin D3 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50169894
(3-{6-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C16H16ClN7O/c17-11-3-1-4-12(7-11)22-16-21-10-20-15(24-16)13-8-18-9-14(23-13)19-5-2-6-25/h1,3-4,7-10,25H,2,5-6H2,(H,19,23)(H,20,21,22,24) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 971 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of cyclin dependent kinase (CDK1) |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169897
(3-{4-[4-Amino-6-(3-chloro-phenylamino)-[1,3,5]tria...)Show InChI InChI=1S/C17H18ClN7O/c18-12-3-1-4-13(10-12)22-17-24-15(23-16(19)25-17)11-5-7-21-14(9-11)20-6-2-8-26/h1,3-5,7,9-10,26H,2,6,8H2,(H,20,21)(H3,19,22,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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B.MOAD
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of vascular endothelial growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50169897
(3-{4-[4-Amino-6-(3-chloro-phenylamino)-[1,3,5]tria...)Show InChI InChI=1S/C17H18ClN7O/c18-12-3-1-4-13(10-12)22-17-24-15(23-16(19)25-17)11-5-7-21-14(9-11)20-6-2-8-26/h1,3-5,7,9-10,26H,2,6,8H2,(H,20,21)(H3,19,22,23,24,25) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of cyclin dependent kinase (CDK1) |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50169893
(3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]tria...)Show SMILES OCCCNc1cncc(c1)-c1ncnc(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C21H25N7O2/c29-9-1-6-23-18-12-16(13-22-14-18)20-24-15-25-21(27-20)26-17-2-4-19(5-3-17)28-7-10-30-11-8-28/h2-5,12-15,23,29H,1,6-11H2,(H,24,25,26,27) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of cyclin dependent kinase (CDK1) |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169895
(3-{5-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(8-13)23-17-22-11-21-16(24-17)12-7-15(10-19-9-12)20-5-2-6-25/h1,3-4,7-11,20,25H,2,5-6H2,(H,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of vascular endothelial growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
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PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 3.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of Casein kinase I |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of vascular endothelial growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169896
(3-{5-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylamino)-[...)Show InChI InChI=1S/C19H20N6O3/c26-5-1-4-21-15-8-13(10-20-11-15)18-22-12-23-19(25-18)24-14-2-3-16-17(9-14)28-7-6-27-16/h2-3,8-12,21,26H,1,4-7H2,(H,22,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 4.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of vascular endothelial growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169893
(3-{5-[4-(4-Morpholin-4-yl-phenylamino)-[1,3,5]tria...)Show SMILES OCCCNc1cncc(c1)-c1ncnc(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C21H25N7O2/c29-9-1-6-23-18-12-16(13-22-14-18)20-24-15-25-21(27-20)26-17-2-4-19(5-3-17)28-7-10-30-11-8-28/h2-5,12-15,23,29H,1,6-11H2,(H,24,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of vascular endothelial growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
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PC cid
PC sid
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of PKB beta |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3/cAMP-dependent protein kinase
(Homo sapiens (Human)-Oryctolagus cuniculus (Rabbit...) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
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PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of Cyclin-dependent kinase 1-cyclin B |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169894
(3-{6-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C16H16ClN7O/c17-11-3-1-4-12(7-11)22-16-21-10-20-15(24-16)13-8-18-9-14(23-13)19-5-2-6-25/h1,3-4,7-10,25H,2,5-6H2,(H,19,23)(H,20,21,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of vascular endothelial growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of Platelet derived growth factor receptor |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of Fibroblast growth factor receptor 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of ERK 2 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50169892
(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)Show InChI InChI=1S/C17H17ClN6O/c18-13-3-1-4-14(10-13)23-17-22-11-21-16(24-17)12-5-7-20-15(9-12)19-6-2-8-25/h1,3-5,7,9-11,25H,2,6,8H2,(H,19,20)(H,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor 1 |
J Med Chem 48: 4535-46 (2005)
Article DOI: 10.1021/jm040214h
BindingDB Entry DOI: 10.7270/Q2833RK0 |
More data for this
Ligand-Target Pair | |
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