new BindingDB logo
myBDB logout

PubMed code 23472886

Compile data set for download or QSAR
Found 21 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50425046
PNG
(CHEMBL2312571 | US9402842, 23)
Show SMILES COC(=O)CC(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1
Show InChI InChI=1S/C23H21N3O5/c1-31-19(28)12-18(27)25-13-7-8-14-17(11-13)23(30)26(10-4-9-24)21-15-5-2-3-6-16(15)22(29)20(14)21/h2-3,5-8,11H,4,9-10,12,24H2,1H3,(H,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>4.45E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427891
PNG
(CHEMBL2323836)
Show SMILES COC(=O)c1ccc2c3C(=O)c4ccccc4-c3n(CCCN(C)C)c(=O)c2c1
Show InChI InChI=1S/C23H22N2O4/c1-24(2)11-6-12-25-20-16-7-4-5-8-17(16)21(26)19(20)15-10-9-14(23(28)29-3)13-18(15)22(25)27/h4-5,7-10,13H,6,11-12H2,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.95E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427898
PNG
(CHEMBL242857)
Show SMILES COc1ccc-2c(c1)C(=O)c1c-2n(CCCN)c(=O)c2ccccc12
Show InChI InChI=1S/C20H18N2O3/c1-25-12-7-8-14-16(11-12)19(23)17-13-5-2-3-6-15(13)20(24)22(18(14)17)10-4-9-21/h2-3,5-8,11H,4,9-10,21H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.84E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50388545
PNG
(CHEMBL1181674 | CHEMBL188130)
Show SMILES NCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C18H14N2O2/c19-9-10-20-16-12-6-2-3-7-13(12)17(21)15(16)11-5-1-4-8-14(11)18(20)22/h1-8H,9-10,19H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.59E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50388546
PNG
(CHEMBL213072 | CHEMBL333363)
Show SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C19H16N2O2/c20-10-5-11-21-17-13-7-2-3-8-14(13)18(22)16(17)12-6-1-4-9-15(12)19(21)23/h1-4,6-9H,5,10-11,20H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 8.66E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427892
PNG
(CHEMBL2322286)
Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccc(Br)cc2c1=O
Show InChI InChI=1S/C21H19BrN2O2/c1-23(2)10-5-11-24-19-15-6-3-4-7-16(15)20(25)18(19)14-9-8-13(22)12-17(14)21(24)26/h3-4,6-9,12H,5,10-11H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.84E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427894
PNG
(CHEMBL425544)
Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C21H20N2O2/c1-22(2)12-7-13-23-19-15-9-4-5-10-16(15)20(24)18(19)14-8-3-6-11-17(14)21(23)25/h3-6,8-11H,7,12-13H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.60E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50396237
PNG
(CHEMBL2172208)
Show SMILES CNc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1
Show InChI InChI=1S/C20H19N3O2/c1-22-12-7-8-13-16(11-12)20(25)23(10-4-9-21)18-14-5-2-3-6-15(14)19(24)17(13)18/h2-3,5-8,11,22H,4,9-10,21H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.22E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50425045
PNG
(CHEMBL2312896 | CHEMBL2322964 | US9402842, 43)
Show SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccc(NCC(O)=O)cc2c1=O
Show InChI InChI=1S/C21H19N3O4/c22-8-3-9-24-19-14-4-1-2-5-15(14)20(27)18(19)13-7-6-12(23-11-17(25)26)10-16(13)21(24)28/h1-2,4-7,10,23H,3,8-9,11,22H2,(H,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 8.40E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50388547
PNG
(CHEMBL1181663 | CHEMBL187863)
Show SMILES NCCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C20H18N2O2/c21-11-5-6-12-22-18-14-8-2-3-9-15(14)19(23)17(18)13-7-1-4-10-16(13)20(22)24/h1-4,7-10H,5-6,11-12,21H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.13E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50396234
PNG
(CHEMBL2172214 | US9402842, 57)
Show SMILES CC(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1
Show InChI InChI=1S/C21H19N3O3/c1-12(25)23-13-7-8-14-17(11-13)21(27)24(10-4-9-22)19-15-5-2-3-6-16(15)20(26)18(14)19/h2-3,5-8,11H,4,9-10,22H2,1H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.47E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50032671
PNG
(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...)
Show SMILES Cc1cc2c(cc1C1(CC1)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
PubMed
n/an/an/an/a 40n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50388549
PNG
(CHEMBL1185123 | CHEMBL390611)
Show SMILES NCCCCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C22H22N2O2/c23-13-7-1-2-8-14-24-20-16-10-4-5-11-17(16)21(25)19(20)15-9-3-6-12-18(15)22(24)26/h3-6,9-12H,1-2,7-8,13-14,23H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.64E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427895
PNG
(CHEMBL2322955)
Show SMILES CNCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C20H18N2O2/c1-21-11-6-12-22-18-14-8-3-4-9-15(14)19(23)17(18)13-7-2-5-10-16(13)20(22)24/h2-5,7-10,21H,6,11-12H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.22E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427896
PNG
(CHEMBL2326683)
Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccc(N)cc2c1=O
Show InChI InChI=1S/C21H21N3O2/c1-23(2)10-5-11-24-19-15-6-3-4-7-16(15)20(25)18(19)14-9-8-13(22)12-17(14)21(24)26/h3-4,6-9,12H,5,10-11,22H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 7.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50396236
PNG
(CHEMBL2172210)
Show SMILES CNCCCn1c2-c3ccccc3C(=O)c2c2ccc(N)cc2c1=O
Show InChI InChI=1S/C20H19N3O2/c1-22-9-4-10-23-18-14-5-2-3-6-15(14)19(24)17(18)13-8-7-12(21)11-16(13)20(23)25/h2-3,5-8,11,22H,4,9-10,21H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.52E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50396238
PNG
(CHEMBL2172212 | US9402842, 62)
Show SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccc(N)cc2c1=O
Show InChI InChI=1S/C19H17N3O2/c20-8-3-9-22-17-13-4-1-2-5-14(13)18(23)16(17)12-7-6-11(21)10-15(12)19(22)24/h1-2,4-7,10H,3,8-9,20-21H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.40E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50388548
PNG
(CHEMBL1182248 | CHEMBL225093)
Show SMILES NCCCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O
Show InChI InChI=1S/C21H20N2O2/c22-12-6-1-7-13-23-19-15-9-3-4-10-16(15)20(24)18(19)14-8-2-5-11-17(14)21(23)25/h2-5,8-11H,1,6-7,12-13,22H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.22E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50425054
PNG
(CHEMBL2312904)
Show SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccc(cc2c1=O)C#N
Show InChI InChI=1S/C22H19N3O2/c1-24(2)10-5-11-25-20-16-6-3-4-7-17(16)21(26)19(20)15-9-8-14(13-23)12-18(15)22(25)27/h3-4,6-9,12H,5,10-11H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>2.07E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427893
PNG
(CHEMBL2322288)
Show SMILES CNCCCn1c2-c3ccccc3C(=O)c2c2ccc(Br)cc2c1=O
Show InChI InChI=1S/C20H17BrN2O2/c1-22-9-4-10-23-18-14-5-2-3-6-15(14)19(24)17(18)13-8-7-12(21)11-16(13)20(23)25/h2-3,5-8,11,22H,4,9-10H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.07E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM50427897
PNG
(CHEMBL2324622)
Show SMILES NCCCn1c2-c3ccccc3Cc2c2ccc(N)cc2c1=O
Show InChI InChI=1S/C19H19N3O/c20-8-3-9-22-18-14-5-2-1-4-12(14)10-16(18)15-7-6-13(21)11-17(15)19(22)23/h1-2,4-7,11H,3,8-10,20-21H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay


J Med Chem 56: 2581-605 (2013)


Article DOI: 10.1021/jm400026k
BindingDB Entry DOI: 10.7270/Q2G44RNG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%