Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206092![]() (CHEMBL3917143 | US10336721, Example 32 | US1096819...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206091![]() (CHEMBL3918231 | US10336721, Example 25 | US1096819...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206062![]() (CHEMBL3890541 | US10968198, Example 44) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206083![]() (CHEMBL3927658 | US10968198, Example 43) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206084![]() (CHEMBL3899123) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206030![]() (CHEMBL3957289 | US10336721, Example 22 | US1096819...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206094![]() (CHEMBL3960793) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206089![]() (CHEMBL3906441) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 147 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50167985![]() (CHEMBL3798384 | US10336721, Example 21 | US1096819...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 161 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206085![]() (CHEMBL3924400) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50167986![]() (CHEMBL3798149 | US10336721, Example 2 | US10968198...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206061![]() (CHEMBL3953102 | US10336721, Example 1 | US10968198...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206087![]() (CHEMBL3897449) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206086![]() (CHEMBL3943378) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206090![]() (CHEMBL3915405) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206093![]() (CHEMBL3925522) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50206088![]() (CHEMBL3945050) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50167988![]() (CHEMBL3798703) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50167988![]() (CHEMBL3798703) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Binding affinity to human MIF by fluorescence polarization assay | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair |