195 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28038324	48	Ring-opened tetrahydro-¿-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms.	Taipei Medical University
15149697	10	Thiol-based SAHA analogues as potent histone deacetylase inhibitors.	Nagoya City University
15109664	4	Three new cyclostellettamines, which inhibit histone deacetylase, from a marine sponge of the genus Xestospongia.	The University Of Tokyo
15109636	14	Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2E,4E)-5-arylpenta-2,4-dienoic acid hydroxyamides.	University College London
14643318	23	Novel histone deacetylase inhibitors: design, synthesis, enzyme inhibition, and binding mode study of SAHA-based non-hydroxamates.	Nagoya City University
14592473	35	Heterocyclic ketones as inhibitors of histone deacetylase.	Abbott Laboratories
14552787	28	A novel series of histone deacetylase inhibitors incorporating hetero aromatic ring systems as connection units.	Abbott Laboratories
12951120	32	Alpha-keto amides as inhibitors of histone deacetylase.	Abbott Laboratories
12749893	37	Indole amide hydroxamic acids as potent inhibitors of histone deacetylases.	Abbott Laboratories
12419380	24	Trifluoromethyl ketones as inhibitors of histone deacetylase.	Abbott Laboratories
12270175	13	Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC).	Abbott Laboratories
28337317	30	Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity.	Wayne State University
27541357	58	Design and Synthesis of Janus Kinase 2 (JAK2) and Histone Deacetlyase (HDAC) Bispecific Inhibitors Based on Pacritinib and Evidence of Dual Pathway Inhibition in Hematological Cell Lines.	National University Of Singapore
28057407	76	Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase.	Georgia Institute Of Technology
27344487	16	2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase.	Taipei Medical University
27717544	75	Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.	Integral Biosciences
27665180	14	Design and synthesis of novel HDAC8 inhibitory 2,5-disubstituted-1,3,4-oxadiazoles containing glycine and alanine hybrids with anti cancer activity.	Acharya Nagarjuna University
27650925	15	Synthesis of a selective HDAC6 inhibitor active in neuroblasts.	University Of Geneva
27606546	218	Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease.	University Of Navarra
27597246	17	Design, synthesis and in vitro evaluation of amidoximes as histone deacetylase inhibitors for cancer therapy.	Qilu Normal University
27377864	55	Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.	Broad Institute Of Mit And Harvard
27186676	186	Development of Purine-Based Hydroxamic Acid Derivatives: Potent Histone Deacetylase Inhibitors with Marked in Vitro and in Vivo Antitumor Activities.	West China Hospital Of Sichuan University
27142751	22	Targeting epigenetic reader and eraser: Rational design, synthesis and in vitro evaluation of dimethylisoxazoles derivatives as BRD4/HDAC dual inhibitors.	China Pharmaceutical University
26996372	10	Identification of new quinic acid derivatives as histone deacetylase inhibitors by fluorescence-based cellular assay.	Sungkyunkwan University
26890116	30	Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity.	University Of Milan
27060764	30	Computer-aided identification of new histone deacetylase 6 selective inhibitor with anti-sepsis activity.	Sungkyunkwan University
26443078	108	Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer.	Sichuan University
26907204	34	Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors.	Shandong University
26705137	31	Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors.	Universidade Federal De Alfenas
26629857	44	Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.	Fudan University
26814680	71	Identification of N-(6-mercaptohexyl)-3-(4-pyridyl)-1H-pyrazole-5-carboxamide and its disulfide prodrug as potent histone deacetylase inhibitors with in vitro and in vivo anti-tumor efficacy.	Shenyang Pharmaceutical University
26804233	38	Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.	Massachusetts General Hospital
26706171	138	Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study.	Shenyang Pharmaceutical University
26689485	18	Orally available stilbene derivatives as potent HDAC inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.	Orchid Chemicals & Pharmaceuticals
26741358	56	Design, synthesis and biological evaluation of N-phenylquinazolin-4-amine hybrids as dual inhibitors of VEGFR-2 and HDAC.	China Pharmaceutical University
26629860	58	Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors.	European Institute Of Oncology
26753813	22	Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid.	University Of Minnesota
26639764	17	Synthesis and biological activity of diisothiocyanate-derived mercapturic acids.	Wroclaw University Of Technology
26475519	40	Hybrids from 4-anilinoquinazoline and hydroxamic acid as dual inhibitors of vascular endothelial growth factor receptor-2 and histone deacetylase.	China Pharmaceutical University
26241876	1	Triazine as a promising scaffold for its versatile biological behavior.	Thapar University
26376355	14	Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors.	University Of Milan
26331334	99	Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities.	Guangzhou Institute Of Biomedicine And Health
26264503	46	Discovery of 1-hydroxypyridine-2-thiones as selective histone deacetylase inhibitors and their potential application for treating leukemia.	University Of Minnesota
26287310	87	Potent and Selective Inhibitors of Histone Deacetylase-3 Containing Chiral Oxazoline Capping Groups and a N-(2-Aminophenyl)-benzamide Binding Unit.	University College London
25637120	94	Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).	St. Jude Children'S Research Hospital
22344701	30	Biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589).	Novartis Institutes For Biomedical Research
25147612	25	Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties.	University Of Florida
26054247	48	Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.	Colorado State University
25953722	102	Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents.	Southeast University
26035239	1	Natural Product Primary Sulfonamides and Primary Sulfamates.	Griffith University
25974739	17	Dual-Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release.	University Of California
25815139	18	Discovery of Novel Multiacting Topoisomerase I/II and Histone Deacetylase Inhibitors.	Fujian University Of Traditional Chinese Medicine
25971769	25	Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.	Methylgene
25906087	14	Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor.	Shandong University
25905694	24	Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells.	Istituto Ortopedico Rizzoli (Ior)
25811792	32	Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.	Yonsei University
25874326	60	Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors.	Southeast University
25805446	30	Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors.	East China Normal University
25800646	40	Macrocyclic compounds as anti-cancer agents: design and synthesis of multi-acting inhibitors against HDAC, FLT3 and JAK2.	Central South University
25113875	14	Indole-3-ethylsulfamoylphenylacrylamides: potent histone deacetylase inhibitors with anti-inflammatory activity.	Taipei Medical University
25070421	33	Evaluation of class I HDAC isoform selectivity of largazole analogues.	Duke University
25042254	7	Novel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarines.	H�Pital Kirchberg
24999749	1	A potent HDAC inhibitor, 1-alaninechlamydocin, from a Tolypocladium sp. induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells.	University Of Oklahoma
24864038	112	Design and synthesis of novel and highly-active pan-histone deacetylase (pan-HDAC) inhibitors.	Nippon Pharmaceutical Chemicals
25563890	49	Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.	R&D Sigma-Tau Industrie Farmaceutiche Riunite
25462271	33	Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity.	Shandong University
25455492	22	Aurones as histone deacetylase inhibitors: identification of key features.	University Of Geneva
25454270	82	Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform.	TBA
25380299	61	Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles.	Technical University Of Denmark
25238284	52	Identification of a novel aminotetralin class of HDAC6 and HDAC8 selective inhibitors.	Roche Pharmaceutical Research And Early Development
25233084	247	ST7612AA1, a thioacetate-¿(¿-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors.	R&D Sigma-Tau Industrie Farmaceutiche Riunite
25218912	103	Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors.	Chinese Academy Of Sciences
25176189	7	Design, synthesis and biological evaluation ofß-boswellic acid based HDAC inhibitors as inducers of cancer cell death.	Csir-Indian Institute Of Integrative Medicine
24900838	30	Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor.	Merck Research Laboratories
24766560	16	Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells.	Taipei Medical University
24588105	56	Synthesis and evaluation of new Hsp90 inhibitors based on a 1,4,5-trisubstituted 1,2,3-triazole scaffold.	Universit£
24565573	35	4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors.	Universit£
24742384	90	Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors.	Universit£
24694055	35	Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity.	Shandong University
24015327	42	Development of a chimeric c-Src kinase and HDAC inhibitor.	University Of Michigan
23570542	48	Design and synthesis of dual-action inhibitors targeting histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme A reductase for cancer treatment.	National Taiwan University
23368884	80	Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif.	Broad Institute Of Mit And Harvard
23493449	8	Development of	Shandong University
24900575	31	Biological evaluation of new largazole analogues: alteration of macrocyclic scaffold with click chemistry.	Chinese Academy Of Sciences
23252603	35	Histone deacetylase (HDAC) inhibitors with a novel connecting unit linker region reveal a selectivity profile for HDAC4 and HDAC5 with improved activity against chemoresistant cancer cells.	Heinrich Heine Universit£T
23116147	30	Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries.	Kyoto Prefectural University Of Medicine
23061376	63	Pharmacokinetic optimization of class-selective histone deacetylase inhibitors and identification of associated candidate predictive biomarkers of hepatocellular carcinoma tumor response.	Roche R & D Center China
23009203	39	Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth.	University Of Illinois At Chicago
23010266	24	Novel histone deacetylase 8 ligands without a zinc chelating group: exploring an 'upside-down' binding pose.	University Of Illinois At Chicago
24900543	27	Macrocyclic peptoid-Peptide hybrids as inhibitors of class I histone deacetylases.	TBA
22642300	160	Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors.	Kyoto Prefectural University Of Medicine
24900500	21	Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.	TBA
22771007	64	Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2.	University Of Illinois At Chicago
22705022	32	Synthesis, biological evaluation and molecular docking studies of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-phenylacrylamide derivatives as inhibitors of HDAC activity.	Nanjing University
22439863	21	Synthesis and biological evaluation of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo.	Taipei Medical University
22465091	28	A novel series of l-2-benzyloxycarbonylamino-8-(2-pyridyl)-disulfidyloctanoic acid derivatives as histone deacetylase inhibitors: design, synthesis and molecular modeling study.	Dalian University Of Technology
21984958	83	Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ¿F508-CFTR.	TBA
21874153	54	Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.	Broad Institute Of Harvard And Mit
20472442	25	On the inhibition of histone deacetylase 8.	University Of Notre Dame
20452225	49	Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids.	Mcgill University
18809328	64	Optimization of a series of potent and selective ketone histone deacetylase inhibitors.	Irbm/Merck Research Laboratories
18182289	127	Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).	Merck Research Laboratories
18247554	134	Histone deacetylase inhibitors: from bench to clinic.	Menarini Ricerche
16987657	45	A series of novel, potent, and selective histone deacetylase inhibitors.	Irbm/Merck Research Laboratories
14613312	106	Histone deacetylase inhibitors.	Aton Pharma
11206439	51	Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 2.	Merck Research Laboratories
11206438	48	Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.	Merck Research Laboratories
22321215	16	Anti-tumor activity of new orally bioavailable 2-amino-5-(thiophen-2-yl)benzamide-series histone deacetylase inhibitors, possessing an aqueous soluble functional group as a surface recognition domain.	Kansai University
21721525	8	In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA).	Harvard Medical School
21548582	57	Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes.	University Of Illinois At Chicago
21634430	218	Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.	S*Bio
21723733	12	Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors.	Novartis Institutes For Biomedical Research
21696956	243	A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold.	Broad Institute Of Harvard And Mit
21080647	27	Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor.	Chroma Therapeutics
21334896	18	Discovery of histone deacetylase 8 selective inhibitors.	Howard Hughes Medical Institute
21417297	220	Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation.	Universita` Degli Studi Di Siena
21256006	11	Structure and property based design, synthesis and biological evaluation of¿-lactam based HDAC inhibitors.	Yonsei University
21145737	12	Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapy.	Roche R & D Center China
21073160	143	Non-Natural Macrocyclic Inhibitors of Histone Deacetylases: Design, Synthesis, and Activity	TBA
19966789	40	Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.	The Scripps Research Institute
20637529	15	Design and synthesis of novel isoxazole-based HDAC inhibitors.	Università
20223566	23	Inside HDAC with HDAC inhibitors.	Universit£
20451378	107	Acylurea connected straight chain hydroxamates as novel histone deacetylase inhibitors: Synthesis, SAR, and in vivo antitumor activity.	S*Bio
20392638	40	Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides.	Takeda California
20381359	17	Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222.	Universit£
20205394	44	Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824).	Novartis Institutes For Biomedical Research
20055418	78	Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents.	University Of Illinois At Chicago
20143778	70	Discovery of 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide (CUDc-101) as a potent multi-acting HDAC, EGFR, and HER2 inhibitor for the treatment of cancer.	Curis
19906529	22	Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors.	Ortho-Biotech Oncology Research & Development
19699639	58	Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors.	Methylgene
19359173	51	Exploring bis-(indolyl)methane moiety as an alternative and innovative CAP group in the design of histone deacetylase (HDAC) inhibitors.	Sigma-Tau Research And Development
19084294	19	Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.	Universit£
19441846	35	Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic properties.	Irbm/Merck Research Laboratories
19419863	58	Isoxazole moiety in the linker region of HDAC inhibitors adjacent to the Zn-chelating group: effects on HDAC biology and antiproliferative activity.	University Of Illinois At Chicago
19419205	28	Design, synthesis, and biological activity of boronic acid-based histone deacetylase inhibitors.	Nagoya City University
19410459	33	Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model.	Irbm/Merck Research Laboratories
19285395	66	N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors.	R&D Sigma-Tau
19268585	30	Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).	Merck Research Laboratories
19181524	46	N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: design, synthesis, SAR studies, and in vivo antitumor activity.	S*Bio
19114304	44	SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103).	Methylgene
19111466	42	Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors.	Methylgene
18951790	109	SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2).	Merck Research Laboratories
18672316	41	Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR.	Institute Of Organic Synthesis
18642892	76	Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6.	University Of Illinois At Chicago
18060775	67	Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2).	Merck Research Laboratories
17892933	10	Omega-alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: a study of chain-length and stereochemical dependence.	Université
17761416	53	The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors.	Merck Research Laboratories
17555962	26	Design of novel histone deacetylase inhibitors.	Merck Research Laboratories
17539623	65	Functional differences in epigenetic modulators-superiority of mercaptoacetamide-based histone deacetylase inhibitors relative to hydroxamates in cortical neuron neuroprotection studies.	University Of Illinois At Chicago
16137884	6	Design and synthesis of phthalimide-type histone deacetylase inhibitors.	The University Of Tokyo Yayoi
14698179	58	Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group.	The Scripps Research Institute
14684344	49	(2-amino-phenyl)-amides of omega-substituted alkanoic acids as new histone deacetylase inhibitors.	Methylgene
29499113	77	Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status.	Medical University Of South Carolina
28416100	19	Synthesis and biological evaluation of largazole zinc-binding group analogs.	Duke University
28415009	51	Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.	Shandong University
28395150	30	4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo.	Taipei Medical University (Tmu)
28391133	6	Design, synthesis and biological evaluation of novel hydroxamates and 2-aminobenzamides as potent histone deacetylase inhibitors and antitumor agents.	Beijing University Of Chemical Technology
28885834	80	Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors.	Second Military Medical University
28336407	8	Development of N-hydroxycinnamamide-based HDAC inhibitors with improved HDAC inhibitory activity and in vitro antitumor activity.	Shandong University
28574690	98	Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups.	Heinrich-Heine-Universit£T D£Sseldorf
19558346	15	Synthesis of a novel series of benzylether-containing cinnamoyl derivatives as histone deacetylase inhibitors.	Shandong University
28196613	34	Potent and Selective EphA4 Agonists for the Treatment of ALS.	Sanford Burnham Prebys Medical Discovery Institute
25699604	74	Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases.	University Of Florida College Of Medicine
1501121	12	Biochemical and pharmacological properties of SR 46349B, a new potent and selective 5-hydroxytryptamine2 receptor antagonist.	Sanofi Recherche
282646	50	Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine.	TBA
37098	14	Binding characteristics of 3H-prazosin to rat brain alpha-adrenergic receptors.	TBA
18291323	20	Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites.	University Of Amsterdam
17825569	48	The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.	Polish Academy Of Sciences
15664859	16	Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.	University Of Michigan