The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27657809 |
12 |
Targeting telomerase with radiolabeled inhibitors. |
University of Oxford |
| 27592503 |
4 |
Synthesis and Enantiomeric Separation of a Novel Spiroketal Derivative: A Potent Human Telomerase Inhibitor with High in Vitro Anticancer Activity. |
Istituto Di Farmacologia Traslazionale |
| 26900656 |
44 |
Dihydropyrazole derivatives as telomerase inhibitors: Structure-based design, synthesis, SAR and anticancer evaluation in vitro and in vivo. |
Anhui Medical University |
| 26883149 |
6 |
Identification of human telomerase inhibitors having the core of N-acyl-4,5-dihydropyrazole with anticancer effects. |
Hefei University of Technology |
| 25965778 |
10 |
Novel myricetin derivatives: Design, synthesis and anticancer activity. |
Guizhou University |
| 25812966 |
11 |
Design and synthesis of celastrol derivatives as anticancer agents. |
Anhui Medical University |
| 25554922 |
9 |
Novel pyrazole-5-carboxamide and pyrazole-pyrimidine derivatives: synthesis and anticancer activity. |
Anhui Medical University |
| 25127152 |
20 |
Novel multi-targeting anthra[2,3-b]thiophene-5,10-diones with guanidine-containing side chains: interaction with telomeric G-quadruplex, inhibition of telomerase and topoisomerase I and cytotoxic properties. |
Russian Academy of Sciences |
| 25062468 |
4 |
Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells. |
Indian Institute of Science |
| 25019478 |
13 |
Flavones: an important scaffold for medicinal chemistry. |
Punjabi University |
| 24957878 |
1 |
i-Motif DNA: structure, stability and targeting with ligands. |
University of East Anglia |
| 24119869 |
9 |
Novel coumarin-dihydropyrazole thio-ethanone derivatives: design, synthesis and anticancer activity. |
Anhui Medical University |
| 24053596 |
10 |
Telomere maintenance as a target for drug discovery. |
University of North Carolina At Chapel Hill |
| 24331756 |
9 |
Pyrrolizines: Promising scaffolds for anticancer drugs. |
Beni-Suef University |
| 23974014 |
16 |
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data. |
Universit£ |
| 23454529 |
3 |
New quinazoline derivatives for telomeric G-quadruplex DNA: effects of an added phenyl group on quadruplex binding ability. |
Sun Yat-Sen University |
| 23312949 |
22 |
Synthesis, biological evaluation, 3D-QSAR studies of novel aryl-2H-pyrazole derivatives as telomerase inhibitors. |
Nanjing University |
| 23279865 |
3 |
Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology. |
National Defense Medical Center |
| 23265905 |
9 |
Design and synthesis of novel 2-methyl-4,5-substitutedbenzo[f]-3,3a,4,5-tetrahydro-pyrazolo[1,5-d][1,4]oxazepin-8(7H)-one derivatives as telomerase inhibitors. |
Guizhou University |
| 23279864 |
16 |
Synthesis, molecular modeling and biological evaluation of 2-aminomethyl-5-(quinolin-2-yl)-1,3,4-oxadiazole-2(3H)-thione quinolone derivatives as novel anticancer agent. |
Shandong University of Technology |
| 22104971 |
3 |
Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA. |
Sun Yat-Sen University |
| 22827615 |
2 |
Stabilization and structural alteration of the G-quadruplex DNA made from the human telomeric repeat mediated by Tröger's base based novel benzimidazole derivatives. |
India Institute of Science |
| 22413845 |
17 |
A new strategy for detection and development of tractable telomerase inhibitors. |
University of California |
| 23021342 |
1 |
Improving the affinity of naphthalene diimide ligand to telomeric DNA by incorporating Zn²¿ ions into its dipicolylamine groups. |
Research Center For Bio-Microsensing Technology |
| 23018096 |
16 |
Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors. |
Nanjing University |
| 22044621 |
4 |
ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide. |
University of North Carolina |
| 22405648 |
7 |
Design and synthesis of novel 5-phenyl-N-piperidine ethanone containing 4,5-dihydropyrazole derivatives as potential antitumor agents. |
Anhui Medical University |
| 20538457 |
14 |
Synthesis and molecular docking studies of novel 2-chloro-pyridine derivatives containing flavone moieties as potential antitumor agents. |
Nanjing University |
| 17954919 |
21 |
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. |
Institut National De La Sant£ |
| 17276687 |
11 |
Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents. |
University of London |
| 11741471 |
13 |
Quadruplex-interactive agents as telomerase inhibitors: synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase. |
University of Texas At Austin |
| 10579817 |
10 |
Molecular modeling studies on G-quadruplex complexes of telomerase inhibitors: structure-activity relationships. |
The Institute of Cancer Research |
| 10411488 |
34 |
2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase. |
The Institute of Cancer Research |
| 9703471 |
13 |
1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase. |
The Institute of Cancer Research |
| 11992780 |
1 |
Shikonin derivatives: synthesis and inhibition of human telomerase. |
Chinese Academy of Science |
| 22336246 |
7 |
JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs. |
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics |
| 21962523 |
20 |
Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents. |
Nanjing University |
| 21486698 |
15 |
Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents. |
Nanjing University |
| 21280624 |
4 |
N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage. |
Sapienza University of Rome |
| 20947362 |
3 |
Synthesis, biological evaluation, and molecular docking studies of 2-chloropyridine derivatives possessing 1,3,4-oxadiazole moiety as potential antitumor agents. |
Nanjing University |
| 20800480 |
14 |
Synthesis and molecular docking study of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential antitumor agents. |
Anhui University of Technology |
| 19726112 |
76 |
Prediction of telomerase inhibitory activity for acridinic derivatives based on chemical structure. |
Central University of Las Villas |
| 19467742 |
17 |
Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands. |
Universit£ |
| 19201200 |
8 |
BRACO19 analog dimers with improved inhibition of telomerase and hPot 1. |
University of North Carolina At Chapel Hill |
| 19053833 |
5 |
Rational design of substituted diarylureas: a scaffold for binding to G-quadruplex motifs. |
University of London |
| 18821749 |
8 |
5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation. |
Sun Yat-Sen University |
| 18754611 |
86 |
Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation. |
University of Padova |
| 18571928 |
2 |
Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. |
National Defense Medical Center |
| 11430001 |
72 |
Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. |
Kumamoto University |
| 17035038 |
23 |
Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition. |
University of Padova |
| 16420044 |
12 |
Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation. |
University of London |
| 15588081 |
30 |
Catecholic flavonoids acting as telomerase inhibitors. |
Bu-Nerviano Medical Sciences |
| 15501053 |
25 |
Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding. |
University of London |
| 15261300 |
6 |
Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors. |
University of London School of Pharmacy |
| 14521409 |
38 |
Trisubstituted acridine derivatives as potent and selective telomerase inhibitors. |
University of London |
| 12657276 |
2 |
Inhibition of telomerase by BIBR 1532 and related analogues. |
University of Texas At Dallas |
| 12639541 |
26 |
Synthesis of 6-formyl-pyridine-2-carboxylate derivatives and their telomerase inhibitory activities. |
Seoul National University |
| 11909720 |
8 |
Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase. |
National Museum of Natural History |
| 11806711 |
6 |
Antitumor polycyclic acridines. 8.(1) Synthesis and telomerase-inhibitory activity of methylated pentacyclic acridinium salts. |
University of Nottingham |
| 11591511 |
12 |
Small molecule/nucleic acid affinity chromatography: application for the identification of telomerase inhibitors which target its key RNA/DNA heteroduplex. |
University of Missouri |
| 11551754 |
43 |
Solid-Phase synthesis of a library constructed of aromatic phosphate, long alkyl chains and tryptophane components, and identification of potent dipeptide telomerase inhibitors. |
Kyushu University |
| 11229776 |
24 |
Development of novel telomerase inhibitors based on a bisindole unit. |
Kyushu University |
| 10999471 |
2 |
A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline. |
Reading University |
| 10498189 |
16 |
Human telomerase inhibition by substituted acridine derivatives. |
The Institute of Cancer Research |
| 10340613 |
4 |
Inhibition of human telomerase by PNA-cationic peptide conjugates. |
University of Cambridge |
| 9822556 |
40 |
Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones. |
The Institute of Cancer Research |
| 9216827 |
1 |
Inhibition of human telomerase by a G-quadruplex-interactive compound. |
Institute For Drug Development |
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