Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337102 ((S)-1-(2-(Diphenylmethyl)benzamido)ethaneboronate ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337101 ((S)-1-(2-(Naphthalen-2-ylcarbonyl)benzamido)ethane...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385268 (CHEMBL2035292) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Binding affinity to Actinomadura sp. R39 PBP | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385267 (CHEMBL2035284) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Binding affinity to Actinomadura sp. R39 PBP | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385263 (CHEMBL2035289) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Binding affinity to Actinomadura sp. R39 PBP | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM39809 (Acylglycineboronic acid, 6) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Binding affinity to Actinomadura sp. R39 PBP | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337101 ((S)-1-(2-(Naphthalen-2-ylcarbonyl)benzamido)ethane...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337094 ((S)-1-(2-Fluoro-6-phenylbenzamido)ethaneboronic ac...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337100 ((S)-1-(2-[(Phenylsulfonyl)amino]benzamido)ethanebo...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337095 ((S)-1-(2,6-Difluorobenzamido)ethaneboronic acid | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385268 (CHEMBL2035292) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385267 (CHEMBL2035284) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337093 ((S)-1-(2-Phenylbenzamido)ethaneboronic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337092 ((S)-1-(2-Benzylbenzamido)ethaneboronic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337091 ((S)-1-(1-Benzothiophene-5-carboxamido)ethaneboroni...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337098 ((R)-1-(2,6-Difluorobenzamido)ethaneboronic acid | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337096 ((S)-1-(2,6-Dichlorobenzamido)ethaneboronic acid | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337099 ((R)-1-(2-Benzylbenzamido)ethaneboronic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50324696 (CHEMBL1221990 | Phenoxyacetyl lactivicin) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Joseph Fourier Curated by ChEMBL | Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x after 60 mins by SDS-PAGE | Nat Chem Biol 3: 565-9 (2007) Article DOI: 10.1038/nchembio.2007.21 BindingDB Entry DOI: 10.7270/Q2JM2BK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337090 ((S)-1-(Naphthalene-2-carboxamido)ethaneboronic aci...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385266 (CHEMBL2035295) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300661 (3-borono-5-(2-methoxybenzamido)benzoic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300664 (3-borono-5-(2-phenoxyacetamido)benzoic acid | CHEM...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300662 (3-borono-5-(thiophene-2-carboxamido)benzoic acid |...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300660 (3-benzamido-5-boronobenzoic acid | CHEMBL575719) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385262 (CHEMBL2035285) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50337097 ((S)-1-(2-(Propan-2-yl)benzamido)ethaneboronic acid...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Actinomadura R39 PBP after 60 mins | ACS Med Chem Lett 2: 219-223 (2011) Article DOI: 10.1021/ml100260x BindingDB Entry DOI: 10.7270/Q25H7GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50300689 (6-chloro-2-(3-(4-chloro-2-methylphenyl)ureido)-3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) Curated by ChEMBL | Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propi... | J Med Chem 52: 5926-36 (2009) Article DOI: 10.1021/jm900625q BindingDB Entry DOI: 10.7270/Q2NV9K68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50300688 (6-chloro-3-(3,4-dichlorophenoxy)-2-(3-(3-(trifluor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) Curated by ChEMBL | Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propi... | J Med Chem 52: 5926-36 (2009) Article DOI: 10.1021/jm900625q BindingDB Entry DOI: 10.7270/Q2NV9K68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300663 (3-borono-5-(2-(thiophen-2-yl)acetamido)benzoic aci...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385263 (CHEMBL2035289) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50300659 (3-borono-5-(2-phenylacetamido)benzoic acid | CHEMB...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385268 (CHEMBL2035292) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.38E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50324697 (CHEMBL1221989 | Lactivicin) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Joseph Fourier Curated by ChEMBL | Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x after 120 mins by SDS-PAGE | Nat Chem Biol 3: 565-9 (2007) Article DOI: 10.1038/nchembio.2007.21 BindingDB Entry DOI: 10.7270/Q2JM2BK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50300687 (2-(5-((4-chlorophenylthio)methyl)-1,3,4-thiadiazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.19E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) Curated by ChEMBL | Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propi... | J Med Chem 52: 5926-36 (2009) Article DOI: 10.1021/jm900625q BindingDB Entry DOI: 10.7270/Q2NV9K68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50300688 (6-chloro-3-(3,4-dichlorophenoxy)-2-(3-(3-(trifluor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propiony... | J Med Chem 52: 5926-36 (2009) Article DOI: 10.1021/jm900625q BindingDB Entry DOI: 10.7270/Q2NV9K68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385263 (CHEMBL2035289) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385267 (CHEMBL2035284) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 2.78E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM39809 (Acylglycineboronic acid, 6) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50300689 (6-chloro-2-(3-(4-chloro-2-methylphenyl)ureido)-3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propiony... | J Med Chem 52: 5926-36 (2009) Article DOI: 10.1021/jm900625q BindingDB Entry DOI: 10.7270/Q2NV9K68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385265 (CHEMBL2035293) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385269 (CHEMBL2035301) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50067893 (3-Carboxyphenylboronicacid | 3-boronobenzoic acid ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385266 (CHEMBL2035295) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.81E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39)) | BDBM50385270 (CHEMBL2035291) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of Actinomadura sp. R39 PBP using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385264 (CHEMBL2035290) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50385262 (CHEMBL2035285) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.06E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Li£ge Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate incubated for 60 mins prior to substrate addition by DTNB... | Bioorg Med Chem 20: 3915-24 (2012) Article DOI: 10.1016/j.bmc.2012.04.018 BindingDB Entry DOI: 10.7270/Q200034N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2X (Streptococcus pneumoniae R6) | BDBM50300687 (2-(5-((4-chlorophenylthio)methyl)-1,3,4-thiadiazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale Jean-Pierre Ebel (CEA/CNRS/UJF) Curated by ChEMBL | Assay Description Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propiony... | J Med Chem 52: 5926-36 (2009) Article DOI: 10.1021/jm900625q BindingDB Entry DOI: 10.7270/Q2NV9K68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50300665 (5-boronothiophene-2-carboxylic acid | CHEMBL573906) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate mixture of (R)-[2-(benzoyl... | J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS | |||||||||||
More data for this Ligand-Target Pair |